[Hub]/) : Traits : Heel bone mineral density (BMD) T-score, automated (left) : ← →

chr6:126,892,049-128,359,362

Best TWAS P=5.83e-74 · Best GWAS P=1.49e-89 conditioned to 2.68e-13

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	RSPO3	0.02	0.03	blup	60	0.02	1.3e-03	19.298	18.2	5.8e-74	0.92	0.02	0.96	TRUE
1	ROSMAP	Brain Pre-frontal Cortex	ECHDC1	0.22	0.11	enet	54	0.12	1.5e-14	-2.877	-5.4	6.2e-08	-0.10	1.00	0.00	TRUE
3	The Cancer Genome Atlas	Breast Invasive Carcinoma	RSPO3	0.02	0.02	blup	60	0.02	2.8e-04	15.735	16.9	2.5e-64	0.86	0.10	0.70	FALSE
5	The Cancer Genome Atlas	Prostate Adenocarcinoma	RSPO3	0.06	0.02	blup	60	0.04	9.3e-05	19.298	15.8	1.6e-56	0.82	0.01	0.97	FALSE
2	YFS	Blood	RNF146	0.01	0.00	bslmm	323	0.00	4.8e-02	0.014	-7.9	2.7e-15	-0.40	0.05	0.11	FALSE