Best TWAS P=1.58e-11 · Best GWAS P=2.08e-36 conditioned to 2.27e-18
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | EYA4 | 0.15 | 0.07 | blup | 567 | 0.12 | 2.0e-14 | -4.9 | -6.3 | 2.5e-10 | -0.49 | 1.00 | 0.00 | FALSE |
| 2 | METSIM | Adipose | VNN2 | 0.08 | 0.06 | lasso | 5 | 0.05 | 3.5e-08 | 4.1 | -5.1 | 2.9e-07 | -0.09 | 1.00 | 0.00 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | EYA4 | 0.03 | 0.03 | enet | 8 | 0.02 | 5.5e-05 | -5.3 | 6.7 | 1.6e-11 | 0.22 | 0.97 | 0.00 | TRUE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | VNN2 | 0.07 | 0.06 | blup | 85 | 0.07 | 7.9e-14 | 4.1 | -5.2 | 2.6e-07 | -0.10 | 0.00 | 0.87 | FALSE |
| 5 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | C6orf192 | 0.05 | 0.02 | enet | 11 | 0.02 | 2.5e-03 | 3.4 | -5.4 | 8.3e-08 | -0.04 | 0.00 | 0.02 | TRUE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | EYA4 | 0.03 | 0.03 | lasso | 2 | 0.02 | 1.1e-03 | -4.9 | -5.1 | 3.1e-07 | -0.32 | 0.27 | 0.02 | TRUE |