[Hub]/) : Traits : Heel bone mineral density (BMD) T-score, automated (left) : ← →

chr12:123,558,705-125,196,704

Best TWAS P=1.86e-10 · Best GWAS P=3.39e-08 conditioned to 0.0701

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
10	METSIM	Adipose	DNAH10	0.03	0.00	bslmm	475	0.01	3.2e-03	4.8	6.4	1.9e-10	0.65	0.04	0.77	TRUE
6	GTEx	Heart Left Ventricle	CCDC92	0.26	0.19	lasso	4	0.21	1.9e-11	5.2	5.7	9.1e-09	0.91	0.02	0.98	FALSE
1	GTEx	Adipose Subcutaneous	RP11-380L11.3	0.09	0.03	lasso	3	0.03	1.4e-03	5.0	5.7	1.1e-08	0.82	0.03	0.96	FALSE
8	GTEx	Thyroid	ZNF664	0.13	0.06	lasso	11	0.08	6.7e-07	5.3	-5.6	2.7e-08	-0.93	0.02	0.97	FALSE
11	The Cancer Genome Atlas	Thyroid Carcinoma	DNAH10	0.04	0.03	lasso	5	0.02	4.6e-03	5.5	5.5	3.3e-08	0.96	0.01	0.90	FALSE
2	GTEx	Adipose Visceral Omentum	RP11-380L11.3	0.15	0.03	lasso	5	0.01	1.4e-01	3.6	5.5	3.5e-08	0.58	0.06	0.59	FALSE
9	METSIM	Adipose	CCDC92	0.10	0.01	bslmm	435	0.06	5.5e-10	-2.0	5.4	7.8e-08	0.56	0.13	0.86	FALSE
5	GTEx	Esophagus Mucosa	CCDC92	0.11	0.02	lasso	4	0.02	1.9e-02	5.2	5.3	9.7e-08	0.94	0.01	0.97	FALSE
4	GTEx	Breast Mammary Tissue (Female)	CCDC92	0.05	-0.01	enet	2	-0.01	6.2e-01	5.3	5.3	1.3e-07	0.95	0.03	0.44	FALSE
7	GTEx	Nerve Tibial	CCDC92	0.16	0.01	enet	6	0.04	6.7e-04	5.5	5.2	2.0e-07	0.73	0.01	0.92	FALSE
3	GTEx	Breast Mammary Tissue (Male)	CCDC92	0.06	-0.01	lasso	3	0.00	4.3e-01	5.2	5.2	2.4e-07	0.87	0.03	0.34	FALSE