[Hub]/) : Traits : Heel bone mineral density (BMD) T-score, automated (left) : ← →

chr12:123,558,705-125,196,704

Best TWAS P=1.86e-10 · Best GWAS P=3.39e-08 conditioned to 0.0701

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RP11-380L11.3 0.09 0.03 lasso 3 0.03 1.4e-03 5.0 5.7 1.1e-08 0.82 0.03 0.96 FALSE
2 GTEx Adipose Visceral Omentum RP11-380L11.3 0.15 0.03 lasso 5 0.01 1.4e-01 3.6 5.5 3.5e-08 0.58 0.06 0.59 FALSE
3 GTEx Breast Mammary Tissue (Male) CCDC92 0.06 -0.01 lasso 3 0.00 4.3e-01 5.2 5.2 2.4e-07 0.87 0.03 0.34 FALSE
4 GTEx Breast Mammary Tissue (Female) CCDC92 0.05 -0.01 enet 2 -0.01 6.2e-01 5.3 5.3 1.3e-07 0.95 0.03 0.44 FALSE
5 GTEx Esophagus Mucosa CCDC92 0.11 0.02 lasso 4 0.02 1.9e-02 5.2 5.3 9.7e-08 0.94 0.01 0.97 FALSE
6 GTEx Heart Left Ventricle CCDC92 0.26 0.19 lasso 4 0.21 1.9e-11 5.2 5.7 9.1e-09 0.91 0.02 0.98 FALSE
7 GTEx Nerve Tibial CCDC92 0.16 0.01 enet 6 0.04 6.7e-04 5.5 5.2 2.0e-07 0.73 0.01 0.92 FALSE
8 GTEx Thyroid ZNF664 0.13 0.06 lasso 11 0.08 6.7e-07 5.3 -5.6 2.7e-08 -0.93 0.02 0.97 FALSE
9 METSIM Adipose CCDC92 0.10 0.01 bslmm 435 0.06 5.5e-10 -2.0 5.4 7.8e-08 0.56 0.13 0.86 FALSE
10 METSIM Adipose DNAH10 0.03 0.00 bslmm 475 0.01 3.2e-03 4.8 6.4 1.9e-10 0.65 0.04 0.77 TRUE
11 The Cancer Genome Atlas Thyroid Carcinoma DNAH10 0.04 0.03 lasso 5 0.02 4.6e-03 5.5 5.5 3.3e-08 0.96 0.01 0.90 FALSE