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Traits
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Traits
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Heel bone mineral density (BMD) T-score, automated (left)
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chr12:52,990,150-54,388,473
Best TWAS P=3.46e-08 · Best GWAS P=2.48e-08 conditioned to 1
53M
53.2M
53.4M
53.6M
53.8M
54M
54.2M
54.4M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
ESPL1
0.05
0.08
lasso
2
0.07
5.5e-08
5.5
-5.5
3.5e-08
-0.97
0.01
0.99
TRUE
1
GTEx
Cells Transformed fibroblasts
PFDN5
0.19
0.14
lasso
5
0.16
7.8e-12
5.4
5.2
1.7e-07
0.95
0.02
0.98
FALSE
3
The Cancer Genome Atlas
Liver Hepatocellular Carcinoma
ESPL1
0.10
0.12
blup
43
0.13
1.6e-06
5.5
-5.2
2.5e-07
-0.94
0.01
0.99
FALSE