Best TWAS P=3.46e-08 · Best GWAS P=2.48e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | PFDN5 | 0.19 | 0.14 | lasso | 5 | 0.16 | 7.8e-12 | 5.4 | 5.2 | 1.7e-07 | 0.95 | 0.02 | 0.98 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ESPL1 | 0.05 | 0.08 | lasso | 2 | 0.07 | 5.5e-08 | 5.5 | -5.5 | 3.5e-08 | -0.97 | 0.01 | 0.99 | TRUE |
| 3 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | ESPL1 | 0.10 | 0.12 | blup | 43 | 0.13 | 1.6e-06 | 5.5 | -5.2 | 2.5e-07 | -0.94 | 0.01 | 0.99 | FALSE |