[Hub]/) : Traits : Heel bone mineral density (BMD) T-score, automated (left) : ←

chr22:40,789,606-42,301,748

Best TWAS P=4.7e-10 · Best GWAS P=2.62e-10 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Cells EBV-transformed lymphocytes	L3MBTL2	0.12	0.08	lasso	6	0.05	1.0e-02	-6.3	-6.2	4.7e-10	0.98	0.01	0.93	TRUE
2	GTEx	Artery Tibial	L3MBTL2	0.05	0.06	lasso	3	0.05	1.0e-04	-6.2	6.2	7.3e-10	-0.99	0.01	0.98	FALSE
4	YFS	Blood	EP300	0.05	0.04	blup	284	0.05	5.2e-15	-6.3	6.0	1.6e-09	-0.79	0.01	0.99	FALSE
1	GTEx	Artery Aorta	L3MBTL2	0.14	0.01	lasso	6	0.04	1.8e-03	-5.1	5.5	3.1e-08	-0.66	0.03	0.88	FALSE
5	The Cancer Genome Atlas	Thyroid Carcinoma	L3MBTL2	0.05	0.03	enet	9	0.04	1.8e-04	4.7	5.4	7.8e-08	-0.58	0.24	0.27	FALSE