Best TWAS P=1.58e-07 · Best GWAS P=2.28e-08 conditioned to 0.0296
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CAPZB | 0.13 | 0.16 | lasso | 4 | 0.16 | 1.8e-19 | -5.2 | 5.1 | 2.9e-07 | -0.88 | 0.03 | 0.97 | FALSE |
| 2 | GTEx | Nerve Tibial | CAPZB | 0.07 | 0.03 | enet | 14 | 0.01 | 3.5e-02 | -4.8 | 5.2 | 1.6e-07 | -0.84 | 0.06 | 0.90 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | CAPZB | 0.28 | 0.39 | lasso | 4 | 0.38 | 9.4e-52 | -5.2 | 5.2 | 1.7e-07 | -0.90 | 0.02 | 0.98 | FALSE |