[Hub]/) : Traits : Heel bone mineral density (BMD) T-score, automated (right) : ← →

chr1:15,123,100-16,844,848

Best TWAS P=5.98e-11 · Best GWAS P=4e-10 conditioned to 0.687

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum RSG1 0.10 0.10 enet 6 0.10 1.1e-05 5.6 5.2 2.3e-07 0.06 0.12 0.76 FALSE
2 GTEx Adipose Visceral Omentum CASP9 0.10 0.05 lasso 11 0.05 8.9e-04 6.1 6.5 6.0e-11 0.90 0.00 0.99 TRUE
3 GTEx Colon Transverse C1orf134 0.19 0.12 lasso 4 0.11 8.6e-06 5.6 5.6 2.3e-08 0.03 0.07 0.92 TRUE
4 GTEx Nerve Tibial RSG1 0.10 0.09 lasso 5 0.10 2.3e-07 5.6 5.3 9.0e-08 0.03 0.11 0.89 FALSE
5 GTEx Whole Blood ARHGEF19-AS1 0.05 0.01 lasso 6 0.01 1.0e-01 5.6 -5.1 2.9e-07 -0.09 0.15 0.39 FALSE
6 ROSMAP Brain Pre-frontal Cortex EPHA2 0.04 0.03 lasso 4 0.02 6.4e-04 5.6 -5.2 2.0e-07 -0.02 0.09 0.89 FALSE
7 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C1orf89 0.03 0.03 enet 6 0.03 2.2e-04 5.6 5.2 1.8e-07 0.02 0.00 0.98 FALSE