Best TWAS P=1.24e-30 · Best GWAS P=3.16e-48 conditioned to 2.61e-19
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | BCO2 | 0.10 | 0.04 | enet | 34 | 0.08 | 5.1e-06 | 0.48 | -6.1 | 1.3e-09 | -0.25 | 0.30 | 0.14 | FALSE |
| 2 | GTEx | Nerve Tibial | RP11-356J5.12 | 0.24 | 0.12 | lasso | 12 | 0.13 | 1.6e-09 | -10.41 | -11.5 | 1.2e-30 | -0.78 | 0.96 | 0.04 | TRUE |
| 3 | GTEx | Vagina | BCO2 | 0.43 | 0.12 | lasso | 7 | 0.11 | 1.8e-03 | 7.23 | -7.4 | 1.8e-13 | -0.52 | 0.09 | 0.18 | FALSE |