Best TWAS P=9.35e-12 · Best GWAS P=9.36e-16 conditioned to 1.92e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Thyroid | CADM1 | 0.55 | 0.53 | lasso | 3 | 0.53 | 2.9e-47 | 6.9 | -6.8 | 9.4e-12 | -0.82 | 0.88 | 0.12 | TRUE |
| 2 | YFS | Blood | CADM1 | 0.11 | 0.11 | bslmm | 631 | 0.12 | 1.1e-35 | 8.0 | -6.8 | 1.2e-11 | -0.94 | 0.00 | 1.00 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | CADM1 | 0.10 | 0.05 | blup | 191 | 0.09 | 2.7e-09 | -6.9 | -5.4 | 8.4e-08 | -0.71 | 0.16 | 0.84 | FALSE |