Best TWAS P=3.73e-09 · Best GWAS P=1.03e-06 conditioned to 0.166
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | RP11-380L11.3 | 0.09 | 0.03 | lasso | 3 | 0.03 | 1.4e-03 | 4.7 | 5.5 | 2.9e-08 | 0.82 | 0.03 | 0.95 | FALSE |
| 2 | GTEx | Adipose Visceral Omentum | RP11-380L11.3 | 0.15 | 0.03 | lasso | 5 | 0.01 | 1.4e-01 | 3.6 | 5.5 | 4.0e-08 | 0.58 | 0.04 | 0.64 | FALSE |
| 3 | GTEx | Heart Left Ventricle | CCDC92 | 0.26 | 0.19 | lasso | 4 | 0.21 | 1.9e-11 | 4.9 | 5.5 | 3.3e-08 | 0.91 | 0.02 | 0.98 | FALSE |
| 4 | METSIM | Adipose | DNAH10 | 0.03 | 0.00 | bslmm | 475 | 0.01 | 3.2e-03 | 4.7 | 5.9 | 3.7e-09 | 0.65 | 0.03 | 0.77 | TRUE |