[Hub]/) : Traits : Heel bone mineral density (BMD) T-score, automated (right) : ← →

chr20:32,819,871-34,556,216

Best TWAS P=6.96e-10 · Best GWAS P=1.07e-09 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	TRPC4AP	0.06	0.01	lasso	6	0.01	3.8e-02	-3.5	-5.5	4.1e-08	-0.80	0.02	0.90	FALSE
2	GTEx	Adipose Subcutaneous	PROCR	0.13	0.05	enet	4	0.05	8.2e-05	5.2	-5.2	2.5e-07	-0.81	0.09	0.91	FALSE
3	GTEx	Artery Aorta	MYH7B	0.22	0.08	lasso	6	0.09	1.3e-05	6.0	5.4	5.3e-08	0.92	0.01	0.99	FALSE
4	GTEx	Artery Aorta	EDEM2	0.13	0.08	enet	10	0.07	6.3e-05	5.1	-5.3	1.4e-07	-0.92	0.02	0.98	FALSE
5	GTEx	Artery Tibial	MYH7B	0.14	0.10	lasso	10	0.12	2.9e-09	6.0	5.6	2.3e-08	0.92	0.01	0.99	FALSE
6	GTEx	Artery Tibial	EDEM2	0.14	0.10	lasso	6	0.08	1.1e-06	5.2	-5.2	1.9e-07	-0.85	0.03	0.97	FALSE
7	GTEx	Brain Caudate basal ganglia	GSS	0.20	0.16	lasso	8	0.11	4.3e-04	6.0	6.0	1.7e-09	0.97	0.02	0.83	FALSE
8	GTEx	Brain Cerebellar Hemisphere	MYH7B	0.18	0.10	lasso	5	0.08	3.7e-03	6.0	6.0	1.8e-09	0.97	0.02	0.96	FALSE
9	GTEx	Brain Cerebellum	MYH7B	0.26	0.30	lasso	4	0.26	2.2e-08	6.0	6.2	7.0e-10	0.98	0.01	0.99	TRUE
10	GTEx	Brain Cerebellum	GSS	0.19	0.12	enet	15	0.19	2.9e-06	6.0	5.5	4.9e-08	0.90	0.02	0.94	FALSE
11	GTEx	Cells EBV-transformed lymphocytes	EDEM2	0.15	0.17	lasso	4	0.15	1.3e-05	5.4	-5.4	8.5e-08	-0.82	0.03	0.94	FALSE
12	GTEx	Esophagus Mucosa	MYH7B	0.11	0.03	enet	20	0.03	2.2e-03	6.0	5.2	2.0e-07	0.85	0.01	0.97	FALSE
13	GTEx	Nerve Tibial	MYH7B	0.21	0.12	lasso	8	0.12	9.7e-09	6.0	5.5	4.1e-08	0.92	0.01	0.99	FALSE
14	GTEx	Spleen	PROCR	0.35	0.31	lasso	6	0.29	4.8e-08	5.2	5.2	1.9e-07	0.80	0.28	0.63	FALSE
15	GTEx	Thyroid	MYH7B	0.06	0.03	enet	15	0.06	3.6e-05	4.4	5.3	9.8e-08	0.77	0.05	0.94	FALSE
16	GTEx	Thyroid	EDEM2	0.13	0.04	enet	13	0.08	4.9e-07	6.1	-5.5	4.5e-08	-0.92	0.01	0.99	FALSE
17	METSIM	Adipose	EDEM2	0.04	0.05	lasso	2	0.04	3.9e-07	5.2	-5.2	1.6e-07	-0.82	0.12	0.88	FALSE
18	METSIM	Adipose	TRPC4AP	0.04	0.03	lasso	5	0.04	1.1e-06	6.0	-5.6	2.7e-08	-0.92	0.01	0.99	FALSE
19	ROSMAP	Brain Pre-frontal Cortex	EDEM2	0.10	0.08	lasso	5	0.07	2.0e-09	5.4	-5.6	2.5e-08	-0.87	0.09	0.91	FALSE
20	YFS	Blood	EDEM2	0.08	0.09	lasso	4	0.10	1.2e-29	5.4	-5.1	3.0e-07	-0.88	0.36	0.64	FALSE