Hub : Genes

PROCR

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0480 0.0250 1.2e-03 0.044 0.023 0.020 0.030 0.032 4.3e-06 7.4e-04 1.7e-03 0.00014 8.0e-05
2 GTEx Adipose Subcutaneous 0.1290 0.0570 2.7e-04 0.047 NA 0.048 NA 0.042 9.3e-05 NA 8.2e-05 NA 2.1e-04
3 GTEx Brain Cerebellar Hemisphere 0.4590 0.1230 8.2e-03 0.014 NA -0.011 NA -0.009 1.4e-01 NA 8.9e-01 NA 6.6e-01
4 GTEx Brain Cerebellum 0.2900 0.0950 2.6e-03 0.008 NA 0.131 NA 0.002 1.8e-01 NA 1.1e-04 NA 2.7e-01
5 GTEx Cells EBV-transformed lymphocytes 0.1890 0.0720 1.7e-03 0.052 NA 0.090 NA 0.067 8.4e-03 NA 7.3e-04 NA 3.2e-03
6 GTEx Cells Transformed fibroblasts 0.1360 0.0460 2.5e-05 0.127 NA 0.101 NA 0.108 9.0e-10 NA 5.5e-08 NA 1.9e-08
7 GTEx Heart Left Ventricle 0.0996 0.0514 4.0e-03 0.036 NA 0.047 NA 0.035 5.2e-03 NA 1.7e-03 NA 5.9e-03
8 GTEx Pancreas 0.4020 0.0960 3.5e-07 0.134 NA 0.151 NA 0.178 2.8e-06 NA 6.1e-07 NA 5.4e-08
9 GTEx Skin Sun Exposed Lower leg 0.0500 0.0290 6.6e-03 0.058 NA 0.023 NA 0.044 1.5e-05 NA 4.9e-03 NA 1.4e-04
10 GTEx Spleen 0.3510 0.0950 1.2e-04 0.311 NA 0.251 NA 0.286 1.0e-08 NA 3.9e-07 NA 4.8e-08
11 METSIM Adipose 0.0395 0.0196 1.2e-03 0.004 0.005 0.003 0.007 0.002 8.1e-02 5.8e-02 1.0e-01 0.02400 1.6e-01
12 YFS Blood 0.0112 0.0061 2.8e-03 0.001 0.006 0.003 0.005 0.003 9.5e-02 3.3e-03 2.3e-02 0.00590 3.9e-02
13 TCGA Breast Invasive Carcinoma 0.0458 0.0211 1.3e-08 0.022 0.045 0.044 NA 0.040 2.2e-05 1.3e-09 1.9e-09 NA 1.0e-08
14 TCGA Colon Adenocarcinoma 0.0890 0.0470 6.5e-04 0.070 0.044 0.043 NA 0.061 7.1e-05 1.5e-03 1.7e-03 NA 2.0e-04
15 TCGA Head and Neck Squamous Cell Carcinoma 0.0299 0.0162 5.3e-04 0.016 0.035 0.019 NA 0.032 5.2e-03 8.3e-05 2.8e-03 NA 1.6e-04
16 TCGA Brain Lower Grade Glioma 0.1001 0.0401 5.7e-11 0.114 0.111 0.112 NA 0.115 7.5e-13 1.5e-12 1.2e-12 NA 5.5e-13
17 TCGA Lung Adenocarcinoma 0.0332 0.0165 5.2e-05 0.029 0.034 0.034 NA 0.029 2.4e-04 6.2e-05 6.1e-05 NA 2.0e-04
18 TCGA Lung Squamous Cell Carcinoma 0.0428 0.0224 4.7e-05 0.014 0.041 0.047 NA 0.038 8.1e-03 1.7e-05 4.5e-06 NA 3.1e-05
19 TCGA Prostate Adenocarcinoma 0.0417 0.0219 6.0e-04 0.046 0.028 0.026 NA 0.030 1.3e-05 5.7e-04 8.7e-04 NA 3.6e-04
20 TCGA Skin Cutaneous Melanoma 0.2020 0.0910 4.4e-04 0.076 0.153 0.139 NA 0.141 4.5e-03 6.9e-05 1.5e-04 NA 1.3e-04
21 TCGA Stomach Adenocarcinoma 0.0980 0.0560 1.7e-04 0.061 0.042 0.041 NA 0.062 3.1e-05 5.4e-04 5.7e-04 NA 2.8e-05
22 TCGA Testicular Germ Cell Tumors 0.1840 0.0870 9.9e-05 0.005 0.135 0.109 NA 0.060 2.1e-01 1.7e-05 1.1e-04 NA 3.6e-03
23 TCGA Thyroid Carcinoma 0.0900 0.0410 2.9e-08 0.061 0.080 0.065 NA 0.063 1.5e-06 3.0e-08 6.0e-07 NA 9.7e-07

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bipolar Disorder (2018) 2.2 3.5 13.7 -0.2 -3.2 -3.7 0.6 1.4 -0.4 -3.7 2.7 -1.8 3.0 -2.1 -1.7 -1.2 -0.2 -0.4 0.0 -0.7 -0.3 -0.3 -1.2 0.0 -3.4 -0.5
Bipolar Disorder or Schizophrenia 2.7 6.5 25.9 0.2 -4.9 -2.3 1.5 1.6 1.0 -5.1 4.6 -3.6 4.8 -2.5 -2.0 -1.0 1.0 -0.1 1.0 -1.0 -0.4 0.7 -0.9 1.4 -3.7 0.0
Depressed Affect (Nagel 2018) 0.5 1.0 2.8 1.4 -0.0 1.3 1.7 -1.1 0.9 -0.1 0.4 -1.1 0.1 1.5 1.0 1.1 1.2 0.6 1.0 -0.0 0.6 0.9 0.9 1.2 1.0 1.0
Depression (Nagel 2018) 0.7 1.0 3.5 1.3 -0.0 0.2 1.2 -0.1 1.2 -0.6 0.4 -1.9 0.6 1.6 -0.2 1.0 1.6 0.2 1.1 -0.7 0.1 1.0 0.6 1.7 1.3 0.8
Intelligence (Savage-Jansen 2018) 1.2 3.7 14.5 -0.8 -3.6 -2.4 2.7 0.8 0.5 -3.0 3.3 -2.1 3.8 -2.4 -1.7 -1.1 0.3 -0.6 0.2 -1.1 -0.7 0.4 -0.7 0.6 -2.6 -0.2
Neuroticism (Nagel 2018) 0.6 1.4 7.0 1.4 0.8 2.6 2.6 -0.5 0.8 0.5 -0.4 -2.1 -0.5 1.7 0.3 0.5 0.9 -0.6 0.2 -1.4 -0.7 0.5 -0.3 0.8 1.3 0.1
Schizophrenia (2018) 1.8 3.8 14.5 0.4 -3.7 0.1 1.5 0.9 1.6 -3.6 3.8 -3.1 3.7 -1.5 -1.2 -0.1 1.4 0.2 1.2 -0.8 0.1 1.1 -0.0 1.7 -2.1 0.6
Schizophrenia vs Biploar Disorder 0.2 0.3 2.2 -0.1 0.4 1.5 -1.2 -0.1 0.4 0.5 -0.3 -0.3 -0.4 0.1 0.6 0.2 0.1 -0.2 -0.1 -0.3 -0.3 0.2 0.2 0.1 0.8 -0.1
Worry (Nagel 2018) 1.1 2.3 10.0 -0.2 0.5 2.5 2.1 1.0 -0.2 0.7 0.4 -2.7 -0.3 0.2 -1.2 -1.2 -0.4 -2.4 -1.1 -3.2 -2.3 -0.8 -2.1 -0.4 0.3 -1.7
Alzheimer’s Disease (in mother) 0.4 0.5 3.0 0.8 -0.1 0.9 1.7 0.5 0.2 -0.4 0.4 -1.5 0.2 0.1 -0.1 -0.2 0.2 -0.7 -0.2 -1.2 -1.1 0.1 -0.7 0.1 0.1 -0.3
Alzheimer’s Disease (in father) 1.2 1.3 4.8 -0.4 0.4 -1.5 0.2 0.5 -2.0 0.5 -0.5 1.3 -0.4 -0.7 -0.1 -1.2 -2.1 -0.8 -1.6 -0.1 -0.7 -1.6 -0.9 -2.2 -1.3 -1.1
Alzheimer’s Disease (including proxy) 0.8 1.1 3.2 -0.2 0.9 -0.9 0.2 0.6 -1.6 0.8 -0.6 0.7 -0.9 -0.3 0.1 -1.0 -1.7 -1.2 -1.5 -0.8 -1.3 -1.5 -1.1 -1.8 -0.5 -1.2
Crohns Disease (2017) 0.2 0.5 2.6 -0.8 0.6 0.2 -1.6 -0.0 0.0 0.9 -0.9 1.4 -0.9 0.4 -0.1 0.4 0.1 0.9 0.6 1.3 0.8 0.2 0.6 0.1 0.5 0.5
Irritable Bowel Disease (IBD) 0.8 2.0 5.2 -2.2 -0.7 -0.7 -2.3 2.1 -1.1 -0.2 0.9 -0.2 0.4 -1.4 -2.2 -1.8 -1.4 -1.3 -1.2 -1.1 -1.4 -1.3 -1.6 -1.2 -1.4 -1.6
Ulcerative Colitis (UC) 3.3 6.1 12.4 -2.6 -2.1 -0.9 -1.9 3.3 -1.7 -1.5 2.6 -1.5 1.9 -2.7 -3.5 -3.2 -2.2 -2.8 -2.3 -2.8 -2.8 -2.1 -2.9 -2.0 -2.9 -2.8
Major Depression (MDD) 1.3 1.6 2.8 1.5 -0.7 0.4 1.0 -1.6 1.7 -1.1 1.1 -1.5 1.0 1.0 1.5 1.4 1.6 1.1 1.5 0.5 1.3 1.5 1.2 1.7 0.6 1.4
Reaction Time 0.9 1.6 4.7 2.2 0.1 -0.4 0.3 -1.1 0.8 0.2 -0.4 0.4 -0.2 1.8 1.8 1.6 1.4 1.6 1.3 1.7 2.1 1.2 1.5 1.3 0.7 1.6
Verbal and Numeric Reasoning (VNR) 1.6 3.8 12.4 -0.6 -3.3 -1.6 2.3 1.0 0.8 -3.2 3.2 -3.1 3.5 -2.3 -1.9 -1.0 0.2 -1.0 0.1 -1.9 -1.2 0.5 -1.1 0.4 -2.5 -0.5
Breast Cancer 0.5 1.3 4.2 1.3 -1.2 1.3 0.2 -1.2 0.3 -0.2 1.4 1.8 1.3 -0.6 0.7 0.7 0.2 1.5 0.8 2.0 1.5 0.7 1.6 0.2 -0.9 1.3
Ovarian Cancer 0.2 0.2 0.8 0.6 0.6 0.4 -0.7 -0.1 -0.3 -0.0 -0.9 0.8 -0.7 0.8 0.5 0.2 -0.3 0.4 0.1 0.6 0.2 -0.1 0.2 -0.3 0.0 0.2
Prostate Cancer 2.1 3.0 12.0 1.1 2.2 1.1 -1.0 -2.7 0.7 1.9 -2.2 1.0 -2.1 1.4 3.5 1.8 1.2 1.2 0.8 1.1 1.0 0.7 1.9 1.0 3.1 1.3
Age at First Birth 2.7 3.9 9.3 -0.8 -2.7 1.2 0.9 1.9 0.1 -2.4 3.1 -2.3 2.7 -2.6 -2.5 -2.1 -0.9 -1.8 -1.0 -2.3 -2.3 -1.0 -2.0 -0.7 -2.6 -1.7
Bipolar Disorder (2011) 3.7 3.6 15.4 -1.2 -3.0 -0.5 -0.1 2.1 -0.9 -2.0 3.3 -0.5 2.7 -2.9 -2.3 -1.9 -1.2 -0.9 -0.8 -0.8 -0.8 -1.0 -1.8 -1.0 -3.9 -1.2
Body Mass Index (BMI) (2010) 0.8 1.1 6.1 1.3 -1.2 -1.8 0.9 0.4 1.0 -2.5 0.5 -1.5 1.6 0.3 -0.3 0.5 1.0 0.6 1.1 0.1 0.6 0.9 0.3 1.2 -0.5 0.8
Coronary Artery Disease (CAD) 3.7 4.4 15.4 1.9 -2.2 -2.6 1.4 0.5 3.2 -3.3 1.5 -3.9 2.8 0.6 -0.5 1.5 2.5 0.9 2.5 -0.3 1.3 2.9 0.9 2.7 -0.4 1.7
Crohns Disease (2012) 0.2 0.3 0.8 -0.9 0.3 -0.5 -0.7 0.9 -0.2 0.6 -0.9 0.8 -0.7 -0.0 -0.9 -0.3 -0.6 0.0 -0.1 0.4 -0.2 -0.2 -0.3 -0.6 -0.0 -0.3
Mean Putamen Volume 0.5 0.5 2.3 -1.1 -0.4 -1.4 -1.3 0.6 -0.5 -0.3 0.8 0.1 0.5 -1.5 -0.4 -0.7 -0.5 -0.5 -0.3 -0.4 -0.0 -0.4 -0.7 -0.4 -0.8 -0.6
Fasting Glucose 1.0 1.2 3.6 -0.8 -0.7 0.8 0.7 0.7 -0.9 0.4 1.0 -0.1 0.5 -1.9 -1.6 -1.6 -0.9 -1.1 -1.0 -1.0 -1.1 -0.8 -1.4 -0.8 -1.7 -1.3
HbA1C 0.4 0.4 1.7 0.6 0.1 -1.2 0.3 -0.6 -0.7 0.5 -0.2 1.3 -0.3 0.0 1.2 0.3 -0.1 0.6 -0.1 0.9 0.8 -0.2 0.4 -0.2 -0.6 0.5
HDL Cholesterol 2.4 3.9 10.1 0.7 2.3 3.2 -1.7 -2.2 0.5 2.8 -2.0 2.9 -2.3 2.1 2.0 1.9 0.4 2.0 1.0 2.7 2.1 0.5 2.2 0.2 2.1 1.6
LDL Cholesterol 0.2 0.4 3.1 0.5 0.0 0.7 -0.1 -1.0 -0.4 0.1 -0.5 0.9 -0.4 -0.5 1.8 0.3 0.2 0.5 0.0 0.7 0.7 0.3 0.6 0.1 0.2 0.5
Lupus 2.2 3.3 6.2 -2.5 -0.2 -0.2 -1.1 2.4 -1.7 -0.1 -0.2 0.1 -0.2 -2.5 -2.0 -2.3 -2.3 -2.4 -2.1 -2.1 -2.0 -1.9 -2.3 -2.2 -1.2 -2.4
Neuroticism (2016) 0.4 0.6 2.4 0.7 0.7 0.8 0.9 -0.6 1.0 0.2 -0.7 -1.0 -0.5 1.5 0.2 0.6 1.0 0.0 0.5 -0.4 0.2 0.7 0.3 1.0 1.4 0.3
Primary Biliary Cirrhosis 1.1 1.6 5.2 -0.8 0.8 -2.3 -2.1 1.1 -1.6 0.8 -0.4 1.3 -0.9 -0.2 -0.1 -1.3 -1.7 -1.2 -1.6 -0.5 -1.1 -1.5 -1.1 -1.6 -0.5 -1.4
Rheumatoid Arthritis 2.0 2.7 9.7 -1.0 3.1 -0.2 -2.9 -0.5 -0.3 3.1 -2.8 2.1 -2.9 1.1 1.5 0.9 0.0 0.0 -0.3 0.7 1.3 -0.2 0.7 -0.2 2.5 0.1
Schizophrenia (2014) 1.2 2.5 10.4 -0.1 -3.1 -0.9 0.6 1.3 0.6 -2.9 3.2 -2.0 3.1 -1.7 -1.4 -0.7 0.5 -0.2 0.4 -0.6 -0.1 0.3 -0.5 0.7 -2.5 -0.0
Triglycerides 0.6 1.0 2.9 -0.1 -0.6 -1.7 -0.9 1.0 -1.7 -1.4 0.4 0.4 0.8 -1.7 -0.0 -1.1 -0.9 -0.5 -1.0 -0.2 -0.8 -0.9 -0.9 -0.9 -1.7 -0.8
Type 2 Diabetes (T2D) (2012) 2.4 2.8 10.5 -1.2 -1.5 -3.2 1.1 1.8 -1.1 -1.1 1.0 -1.2 0.9 -2.3 -1.9 -2.1 -1.4 -1.7 -1.5 -1.7 -1.4 -1.6 -1.8 -1.2 -2.3 -1.5
Ulcerative Colitis 3.3 4.8 10.7 -2.8 -1.2 -1.7 -2.5 3.3 -1.8 -0.5 1.7 -0.5 0.9 -2.1 -3.2 -2.9 -2.2 -2.4 -2.1 -2.2 -2.3 -2.2 -2.5 -1.9 -2.3 -2.5
Blood Eosinophil Count 0.3 2.2 8.6 0.3 -1.0 -2.9 0.8 -0.5 1.8 -1.8 0.4 -0.7 1.0 1.3 0.8 1.5 1.7 1.7 2.0 1.3 2.0 1.7 1.6 1.8 0.1 1.8
Blood Platelet Count 0.1 1.6 4.5 -2.1 -1.2 -0.5 1.8 0.8 -0.6 0.4 2.1 -1.1 1.1 -1.5 -1.8 -1.2 -1.0 -1.1 -0.8 -1.2 -0.2 -0.7 -1.3 -0.9 -2.0 -0.8
Blood Red Count 0.5 5.1 30.4 0.4 -2.3 1.9 5.5 1.9 -0.2 -2.2 2.4 -3.8 2.4 -1.4 -2.7 -1.7 -0.1 -2.2 -1.0 -3.3 -1.5 -0.9 -2.2 -0.1 -1.8 -1.4
Blood White Count 0.3 1.9 14.3 1.5 -1.3 -0.9 1.2 1.0 0.9 -2.3 1.6 -3.8 1.7 -0.3 -0.9 -0.2 1.1 -0.7 0.6 -1.9 -0.9 0.6 -0.9 1.3 -0.5 -0.2
Heel T-Score 3.6 28.3 96.8 1.6 -9.3 -0.9 7.9 1.7 2.5 -9.8 9.3 -9.8 9.4 -4.2 -2.6 -2.0 1.7 -1.7 1.3 -4.4 -2.1 1.6 -2.6 2.3 -6.9 -0.3
BMI 1.9 11.1 20.3 3.3 -3.1 -3.6 1.6 -2.1 4.2 -4.4 2.2 -2.2 3.8 1.2 1.4 3.3 4.1 3.7 4.5 2.9 3.8 4.3 3.2 4.4 -0.6 4.0
Height 16.8 323.0 1062.8 -18.9 -12.8 -13.1 -8.4 30.8 -11.8 -10.9 13.1 -10.0 11.3 -20.3 -32.6 -21.5 -14.8 -20.5 -15.8 -21.3 -20.3 -14.3 -19.9 -12.5 -15.2 -19.5
Waist Hip Ratio (WHR) 3.6 16.3 53.8 1.3 7.3 2.0 -1.3 -5.2 0.5 6.3 -6.4 3.4 -6.8 4.2 7.0 3.5 1.2 1.6 0.7 2.2 2.5 0.7 2.6 0.5 6.4 1.7
Systolic Blood Pressure 1.0 4.9 19.9 -2.6 -2.1 -2.8 -0.5 3.6 -1.7 -1.5 2.5 0.4 2.0 -2.4 -4.5 -2.3 -2.2 -1.2 -1.4 -0.7 -1.0 -1.6 -1.8 -1.9 -3.6 -1.6
Smoking Status 1.6 3.9 12.2 0.8 3.4 1.3 -0.8 -1.8 0.5 3.2 -3.5 1.6 -3.4 2.6 2.2 1.8 0.7 1.2 0.7 1.4 1.0 0.8 1.6 0.4 3.4 1.0
Allergy or Eczema 1.2 3.2 7.2 -1.0 -1.3 0.5 0.5 1.6 -1.8 -1.0 2.2 -0.9 1.6 -2.7 -1.9 -2.2 -1.7 -2.2 -2.0 -2.2 -1.7 -1.9 -2.3 -1.6 -2.3 -2.0
Cardiovascular Disease 1.8 5.9 11.5 2.5 0.2 -2.2 0.9 -2.5 3.4 -1.6 -0.6 -0.8 0.4 2.3 2.4 3.1 3.4 2.6 3.2 1.9 2.6 3.3 2.8 3.4 2.2 2.8
Hypothyroidism (self reported) 0.4 1.0 9.7 -0.7 0.1 -3.1 -1.9 1.0 -1.2 0.1 0.2 0.9 0.2 -0.5 -1.0 -0.4 -1.0 0.0 -0.6 0.5 0.2 -0.9 0.1 -0.9 -0.8 -0.2
Respiratory disease 0.9 1.9 4.3 -1.7 0.1 -1.0 -0.8 1.6 -1.3 0.4 0.6 -0.7 0.1 -1.1 -1.8 -1.7 -1.4 -1.8 -1.4 -1.6 -2.0 -1.3 -2.1 -1.3 -1.2 -1.9
Type 2 Diabetes (T2D) (2018) 0.1 0.2 1.3 0.0 -0.5 -1.1 -0.1 -0.5 0.2 -0.5 0.6 0.4 0.8 -0.7 0.3 0.1 0.1 0.5 0.4 0.5 0.3 0.3 0.0 0.2 -0.7 0.2
Lung FEV1/FVC ratio 3.0 15.3 27.8 -4.2 -1.7 -3.0 -2.0 5.0 -3.5 -1.6 1.7 -2.0 1.4 -5.3 -4.7 -4.8 -4.1 -5.0 -4.4 -5.1 -4.9 -4.2 -4.6 -3.8 -3.1 -4.7
Lung FVC 5.6 28.4 98.8 4.7 8.2 3.8 -1.7 -7.7 1.5 5.9 -7.9 2.6 -7.9 7.2 9.9 5.0 2.6 2.9 1.8 3.0 2.4 1.8 4.2 1.8 8.8 3.1
Neuroticism 0.6 1.4 7.7 1.3 -0.1 1.2 2.5 -0.2 1.1 -0.5 0.2 -2.8 0.4 1.7 -0.3 0.5 1.4 -0.6 0.6 -1.6 -0.7 0.7 -0.1 1.4 1.1 0.3
Chronotype (morning person) 2.6 6.1 12.3 -3.1 0.8 -0.5 -1.3 3.5 -2.9 1.2 0.2 -0.6 -1.0 -1.8 -3.0 -2.8 -3.0 -3.1 -2.9 -3.0 -2.8 -2.9 -3.3 -3.0 -1.3 -3.1
Hair Pigment 9.0 257.5 990.2 12.1 17.5 28.8 31.5 -5.3 12.2 9.9 -18.6 -23.4 -16.6 23.4 9.4 8.3 13.0 -6.3 4.4 -16.6 -8.3 7.0 -1.7 11.0 27.5 0.7
Tanning 19.1 233.3 961.0 -14.3 -15.4 -24.4 -31.0 6.8 -13.4 -7.1 18.1 21.6 14.2 -23.2 -10.3 -9.7 -13.8 3.7 -5.9 13.2 5.8 -8.8 -0.7 -12.0 -26.1 -2.8
Hand grip strength (left) 9.1 24.1 84.1 -4.5 -4.1 -2.2 -1.4 8.4 -3.1 -4.1 3.6 -3.6 3.7 -5.8 -9.2 -5.7 -3.9 -5.0 -3.7 -5.6 -5.6 -3.7 -5.5 -3.3 -5.1 -4.9
Number of treatments/medications taken 0.3 0.6 3.3 1.7 0.5 -1.2 0.4 -0.1 0.5 -0.4 0.3 -1.8 0.0 1.1 0.5 0.5 0.6 -0.4 0.2 -0.9 -0.3 0.4 0.2 0.5 0.9 0.2
Average weekly spirits intake 0.4 0.5 2.2 1.1 0.4 -0.4 -0.3 0.1 0.7 -1.0 -0.9 -1.5 -0.2 0.9 0.3 0.6 0.7 0.3 0.7 -0.4 -0.5 0.7 0.1 0.8 0.7 0.3
Sensitivity / hurt feelings 1.0 1.8 6.6 2.0 2.0 2.6 0.0 -0.9 0.5 1.4 -1.6 -1.2 -1.9 1.8 1.8 0.9 0.7 -0.4 0.0 -0.8 -0.3 0.2 0.4 0.5 2.5 0.3
Frequency of depressed mood in last 2 weeks 1.7 2.3 8.6 2.2 1.5 -0.5 0.6 -1.2 1.3 0.3 -1.3 -0.9 -0.7 2.9 1.3 2.2 1.9 1.1 1.5 0.5 1.2 1.3 1.6 1.9 2.4 1.6
Hearing difficulty/problems: Yes 1.3 2.0 6.5 -0.6 -0.3 2.6 2.4 0.3 -1.3 0.7 0.9 -1.1 0.2 -1.7 -0.6 -1.4 -1.3 -1.6 -1.6 -1.9 -1.8 -1.5 -1.5 -1.3 -0.7 -1.4
Relative age of first facial hair 2.6 5.4 14.9 0.4 3.7 2.5 -1.0 -2.7 0.4 3.4 -3.9 2.9 -3.6 2.2 3.0 2.1 0.7 1.6 0.6 2.1 1.8 0.5 1.9 0.3 3.4 1.3
Other serious medical condition/disability diagnosed by doctor 0.9 1.2 4.9 0.9 1.6 -0.2 0.4 -0.0 0.4 0.7 -1.5 -2.1 -1.5 1.3 1.2 0.4 0.7 -0.9 -0.2 -1.7 -1.1 0.1 -0.2 0.5 2.2 -0.3
Ever used hormone-replacement therapy (HRT) 0.4 0.5 1.8 0.2 -0.1 0.4 0.1 0.8 -0.6 -0.2 0.6 -1.3 0.3 0.1 -0.4 -0.7 -0.4 -0.9 -0.5 -1.2 -1.0 -0.7 -1.1 -0.4 -0.7 -0.8
Ever had hysterectomy (womb removed) 0.3 0.4 0.8 0.2 0.8 0.2 -0.8 -0.5 0.1 0.8 -0.5 0.5 -0.9 0.5 0.8 0.6 0.4 0.6 0.5 0.7 0.8 0.1 0.6 0.3 0.9 0.5
Systolic blood pressure, automated reading 2.4 7.1 20.2 -1.8 -3.0 -1.6 0.8 3.6 -1.8 -2.4 3.6 -1.7 2.9 -3.2 -4.3 -3.1 -2.2 -2.2 -1.8 -2.2 -2.2 -1.9 -3.0 -1.9 -4.5 -2.3
Eye problems/disorders: Diabetes related eye disease 0.5 0.6 2.4 0.2 1.6 -0.1 -0.1 -0.7 0.2 1.2 -1.3 0.7 -1.3 0.7 0.8 0.7 0.5 0.3 0.4 0.4 0.4 0.3 0.4 0.4 1.4 0.4
Angina 1.5 2.0 4.6 1.9 -0.6 0.2 1.0 -0.8 2.1 -1.1 0.8 -1.6 0.9 0.7 1.0 1.7 2.0 1.3 2.0 0.7 1.6 2.1 1.4 2.1 0.7 1.8
Medication for hormone replacement therapy 0.4 0.4 3.2 -0.4 1.1 0.7 -1.8 0.1 -0.8 1.1 -0.6 0.6 -1.0 0.5 0.2 -0.0 -0.2 -0.1 -0.3 0.1 -0.0 -0.5 -0.4 -0.3 0.1 -0.3
Vitamin and mineral supplements 2.0 2.7 5.6 1.7 0.4 0.5 2.2 -2.2 1.6 0.6 -1.0 1.2 -0.4 1.4 1.7 2.0 1.7 2.1 1.7 2.4 2.1 1.8 2.0 1.6 1.1 2.1
Supplements: Zinc 1.6 1.7 5.7 -1.5 -1.6 -1.4 -1.0 2.0 -1.2 -1.0 2.2 0.6 1.4 -1.5 -2.0 -1.3 -1.1 -0.2 -0.6 0.2 -0.2 -0.9 -0.7 -1.0 -2.4 -0.6
Medication: Co-codamol 1.6 1.9 6.8 2.0 1.8 -0.8 -0.0 -1.3 0.8 1.2 -1.8 -0.5 -1.8 2.5 1.8 1.4 1.4 0.4 0.7 0.1 0.5 0.8 1.0 1.2 2.6 0.9
Medication: Metformin 0.1 0.2 2.1 -0.4 -0.2 -1.4 0.1 0.1 -0.1 -0.3 0.2 0.3 0.4 -0.1 -0.3 0.1 0.2 0.5 0.4 0.5 0.4 0.1 0.2 0.2 -0.5 0.3
Diabetes (father) 0.5 0.7 4.6 -0.8 -0.8 -2.1 -0.3 0.5 -0.2 -0.7 0.6 0.9 0.9 -0.3 -1.1 0.0 -0.2 0.7 0.4 1.1 1.2 0.1 0.4 -0.1 -1.3 0.5
Diabetes (mother) 2.0 2.5 7.8 -0.8 -1.0 -2.0 0.6 2.8 -1.2 -1.5 1.3 -1.7 1.2 -0.8 -2.8 -1.7 -1.1 -1.7 -1.2 -1.8 -1.2 -1.2 -2.1 -1.0 -2.1 -1.5
Severe depression (siblings) 1.6 1.8 3.5 0.0 -1.3 -1.3 -0.0 1.1 -1.0 -1.5 1.7 -1.7 1.3 -1.8 -0.7 -1.5 -1.0 -1.6 -1.2 -1.8 -1.9 -1.1 -1.6 -0.9 -1.7 -1.3
Pack years adult smoking proportion 1.5 2.3 6.7 -1.1 0.4 -1.7 -1.8 2.2 -1.1 0.3 0.0 -1.2 -0.5 -0.9 -1.2 -1.5 -1.3 -2.6 -1.9 -2.6 -1.6 -1.4 -1.9 -1.3 -0.1 -2.0
Impedance of leg (right) 1.9 9.4 33.0 3.4 2.4 5.7 2.2 -5.5 2.4 2.2 -2.2 0.7 -2.2 3.4 5.7 3.1 2.4 2.2 1.9 1.8 1.8 2.2 2.7 2.0 3.7 2.3
Leg fat-free mass (left) 9.6 50.9 187.7 -6.8 -6.8 -8.6 -3.0 12.7 -3.8 -6.9 6.3 -4.5 6.6 -8.2 -13.7 -7.6 -4.9 -6.6 -4.7 -7.0 -6.3 -4.5 -6.8 -3.8 -7.7 -6.2
Trunk fat percentage 1.4 5.6 13.4 3.3 -1.5 -0.7 2.2 -0.6 3.5 -2.8 1.2 -3.5 2.1 2.0 0.6 2.4 3.5 1.5 3.0 0.2 1.8 3.1 2.1 3.7 1.3 2.5
Hand grip strength (right) 10.7 29.0 100.0 -5.2 -4.8 -3.4 -1.6 9.1 -3.2 -4.6 4.2 -3.7 4.2 -6.6 -10.0 -6.3 -4.1 -5.4 -3.9 -5.9 -6.1 -3.8 -6.0 -3.4 -5.7 -5.3
Townsend deprivation index at recruitment 4.4 6.2 16.1 1.2 3.7 0.0 -1.3 -2.8 1.0 3.1 -3.9 2.0 -3.4 3.1 3.8 2.6 1.8 1.9 1.4 2.3 2.1 1.2 2.3 1.5 4.0 1.8
Current tobacco smoking 1.6 2.5 8.2 0.9 2.5 0.5 -2.1 -0.6 0.6 2.2 -2.4 1.2 -2.4 2.8 1.5 1.6 0.9 1.0 0.7 1.1 0.9 0.6 1.5 0.7 2.9 0.9
Average weekly fortified wine intake 2.1 2.4 5.8 -1.3 -0.2 1.3 0.2 1.8 -2.0 0.2 0.3 0.3 0.2 -1.2 -2.4 -2.2 -1.9 -1.5 -1.7 -1.1 -1.8 -1.9 -2.2 -1.8 -1.9 -1.9
Maternal smoking around birth 2.3 3.3 12.5 -0.5 3.3 -0.9 -1.9 -1.5 0.4 2.6 -3.5 1.4 -3.1 2.1 2.8 1.4 0.3 0.2 0.1 0.5 1.3 0.2 1.1 0.1 3.2 0.4
Fed-up feelings 2.1 3.8 6.6 2.5 -0.5 0.3 1.8 -2.1 2.2 -0.7 0.7 -1.0 0.7 2.3 2.2 2.6 2.4 2.0 2.3 1.4 2.4 2.3 2.5 2.4 1.3 2.6
Frequency of unenthusiasm / disinterest in last 2 weeks 1.1 1.5 5.8 1.4 0.9 -0.0 1.2 -0.7 1.1 -0.2 -0.6 -2.0 -0.3 2.3 0.8 1.2 1.9 0.1 1.1 -0.7 0.1 1.0 0.7 1.9 2.4 0.8
Relative age voice broke 1.6 2.4 7.8 0.4 2.6 2.8 1.0 -2.3 0.0 2.2 -2.8 0.6 -2.6 1.0 2.6 1.0 0.5 0.3 0.1 0.3 0.3 -0.0 0.5 0.2 2.4 0.4
Taking other prescription medications 0.3 0.4 1.8 0.4 1.3 -1.0 -0.2 0.2 -0.9 1.3 -0.5 0.4 -1.0 0.3 0.1 -0.2 -0.7 -0.6 -0.7 -0.3 -0.1 -0.7 -0.4 -0.8 0.3 -0.4
Age when periods started (menarche) 2.4 5.7 15.1 -3.6 1.5 3.9 -1.2 0.5 -3.1 3.1 -0.6 2.5 -1.8 -2.4 -0.4 -2.2 -2.8 -2.2 -3.0 -1.3 -2.1 -3.0 -2.2 -3.0 -0.5 -2.7
Bilateral oophorectomy (both ovaries removed) 0.3 0.3 1.1 -0.1 -0.1 0.4 -0.7 -0.6 -0.4 0.9 1.0 0.8 -0.2 -0.0 1.0 0.1 -0.0 0.6 0.2 1.0 0.7 -0.1 0.3 -0.0 -0.4 0.4
Heel bone mineral density (BMD) T-score, automated (left) 4.2 9.4 37.0 1.1 -5.7 -0.8 5.3 0.4 2.0 -5.6 5.4 -4.0 6.1 -2.4 -1.3 -0.6 1.0 0.1 1.3 -0.9 -0.2 1.7 -0.7 1.4 -4.4 0.5
Tinnitus: Yes, but not now, but have in the past 0.6 0.7 2.5 -0.8 -0.2 1.1 0.2 0.9 -0.5 -0.2 0.0 -1.3 0.1 -0.3 -0.5 -1.1 -0.3 -1.4 -0.6 -1.6 -1.1 -0.8 -1.2 -0.2 0.0 -1.1
Qualifications: CSEs or equivalent 2.2 2.8 7.6 0.5 2.5 1.4 -2.1 -1.6 0.7 1.7 -2.8 2.0 -2.3 2.3 2.3 1.5 0.5 1.4 0.8 1.8 1.1 0.8 1.4 0.4 2.5 0.9
Serious illness, injury or assault to yourself 1.0 1.2 2.7 1.5 0.8 -0.4 -0.0 -1.1 1.4 -0.0 -0.8 -0.8 -0.2 1.3 1.6 1.3 1.6 0.8 1.3 0.4 0.6 1.3 0.9 1.6 1.5 1.0
High blood pressure 0.9 2.6 6.4 1.4 0.1 -2.5 0.3 -1.8 1.8 -0.7 0.2 0.3 0.4 1.7 1.7 2.0 1.7 1.7 1.8 1.8 2.3 1.8 2.2 1.7 1.1 1.9
Hayfever, allergic rhinitis or eczema 0.7 1.6 3.8 -0.4 -1.0 1.3 -0.2 1.4 -1.1 -0.9 1.7 -0.3 1.3 -1.9 -1.7 -1.3 -1.3 -1.4 -1.3 -1.3 -1.0 -1.2 -1.3 -1.1 -1.7 -1.2
Multivitamins +/- minerals 2.5 3.2 7.6 -1.2 -2.0 -0.3 -1.0 2.6 -1.4 -1.3 2.6 -1.2 1.8 -2.2 -2.3 -2.0 -1.8 -1.6 -1.4 -1.7 -1.4 -1.5 -1.7 -1.6 -2.8 -1.5
Stomach or abdominal pain in last month 0.5 0.7 3.6 1.4 0.0 0.1 1.9 -0.4 0.9 -0.2 -0.5 -1.4 -0.2 0.9 0.4 0.6 1.0 0.3 0.7 -0.1 0.3 0.8 0.4 1.0 0.8 0.7
Supplements: Glucosamine 2.3 3.1 14.9 1.4 -2.7 0.7 1.5 0.7 0.7 -2.9 2.7 -3.9 2.8 -1.5 -0.9 -0.8 0.5 -0.9 0.2 -2.0 -1.7 0.4 -1.2 0.7 -2.0 -0.4
Diverticular disease/diverticulitis (self-reported) 0.7 0.9 2.9 1.7 -0.2 -0.5 0.2 -1.3 1.5 -0.5 -0.0 -1.3 0.3 1.1 1.1 1.0 1.1 0.5 0.9 0.2 0.5 1.2 0.9 1.2 0.9 0.9
Medication: Atenolol 1.6 1.9 5.0 1.3 -0.2 -0.6 0.0 -0.2 2.2 -0.5 0.3 -0.3 0.4 1.1 0.4 1.9 2.0 1.7 2.1 1.4 2.0 2.2 1.5 2.0 0.5 1.9
Medication: Levothyroxine sodium 0.2 0.4 3.7 0.1 -0.2 -1.9 -0.3 0.6 -0.5 -0.3 0.3 -0.5 0.4 -0.4 -1.0 -0.3 -0.5 -0.4 -0.5 -0.5 -0.7 -0.3 -0.1 -0.4 -0.2 -0.4
Sitting height 23.2 164.8 533.6 -12.5 -13.2 -9.8 -4.2 21.0 -7.5 -11.3 13.4 -7.0 12.5 -16.3 -23.1 -14.7 -9.8 -12.3 -9.3 -12.8 -12.4 -8.7 -12.9 -7.9 -14.9 -11.9
Chronic bronchitis/emphysema (father) 0.3 0.4 1.1 0.3 0.8 0.3 -0.8 0.1 -1.0 1.0 -0.1 0.9 -0.6 0.4 0.3 -0.3 -0.9 -0.5 -0.9 -0.0 -0.3 -0.8 -0.1 -1.0 0.2 -0.5
High blood pressure (mother) 0.5 0.7 3.9 -0.7 -0.9 -2.0 -0.2 0.6 0.0 -1.1 0.9 0.1 1.1 -1.4 -1.5 -0.3 -0.2 -0.0 -0.1 0.3 0.6 -0.1 -0.2 -0.0 -1.3 -0.1
Body mass index (BMI) 2.1 9.1 16.3 3.6 -2.4 -2.9 2.3 -1.8 3.8 -3.5 1.8 -2.4 3.0 1.7 1.5 3.1 3.9 3.2 4.0 2.3 3.3 3.9 3.1 4.0 -0.0 3.7
Impedance of leg (left) 2.2 10.6 37.8 3.4 2.6 5.9 2.0 -5.8 2.3 2.8 -2.1 0.9 -2.5 3.5 6.1 3.3 2.6 2.4 2.1 2.1 2.0 2.3 2.9 2.2 4.1 2.5
Leg predicted mass (left) 9.7 51.2 187.7 -6.9 -6.7 -8.5 -3.1 12.8 -3.8 -6.8 6.3 -4.5 6.5 -8.2 -13.7 -7.6 -5.0 -6.7 -4.7 -7.0 -6.3 -4.5 -6.9 -3.9 -7.7 -6.2
Trunk fat mass 1.3 5.8 19.7 0.5 -3.4 -3.4 1.0 3.4 1.7 -4.4 3.1 -4.4 3.9 -1.1 -3.7 -0.5 1.3 -1.0 0.9 -2.2 -0.7 1.1 -0.6 1.7 -1.4 0.0
Waist circumference 0.6 2.2 12.7 1.1 -0.8 -3.6 0.6 0.6 2.0 -2.1 0.7 -2.1 1.5 0.5 -0.5 1.2 1.9 0.6 1.7 -0.0 1.1 1.8 0.9 2.1 0.4 1.3
Number of incorrect matches in round 0.6 1.1 3.0 -0.4 0.6 0.7 0.3 0.2 -1.7 0.8 -0.6 0.5 -0.7 -0.6 -0.4 -1.3 -1.4 -1.1 -1.5 -0.8 -1.3 -1.6 -1.2 -1.5 -0.3 -1.3
Past tobacco smoking 3.4 6.3 18.1 -1.4 -4.2 -1.5 0.7 2.9 -0.5 -3.7 4.2 -2.4 4.0 -3.3 -3.0 -2.4 -1.0 -1.5 -0.7 -1.9 -1.5 -0.8 -2.1 -0.6 -4.2 -1.4
Alcohol usually taken with meals 0.5 0.8 2.9 0.5 -1.5 -0.8 1.3 0.1 0.8 -1.5 1.4 0.1 1.7 -0.7 -0.8 0.3 0.3 0.8 0.7 0.6 0.2 0.8 0.4 0.3 -1.3 0.7
Nervous feelings 0.8 1.5 6.4 0.6 1.2 1.4 1.5 -0.2 0.4 0.9 -1.2 -2.5 -1.3 1.2 0.3 -0.3 0.4 -1.6 -0.5 -2.4 -1.9 -0.1 -1.2 0.3 1.5 -0.9
Frequency of tenseness / restlessness in last 2 weeks 2.6 4.0 12.7 2.7 1.6 -1.4 1.4 -1.8 1.9 -0.3 -2.2 -2.3 -1.1 3.6 2.1 2.3 2.8 1.0 1.9 -0.1 0.5 1.7 1.4 2.7 3.2 1.6
Hearing difficulty/problems with background noise 2.7 4.3 11.6 -1.5 0.4 1.0 0.9 1.7 -2.4 0.6 -0.0 -1.6 -0.7 -1.8 -1.5 -2.5 -2.0 -3.1 -2.8 -3.4 -3.4 -2.7 -2.8 -2.1 -0.4 -2.8
Hair/balding pattern: Pattern 2 1.9 2.4 5.8 2.4 0.6 2.4 2.0 -2.2 1.8 -0.0 -1.0 -1.2 -0.6 2.1 1.7 1.6 1.7 1.0 1.2 0.3 0.3 1.5 1.5 1.6 2.3 1.4
Had menopause 1.3 1.6 3.9 -1.8 -0.9 0.9 0.0 1.4 -0.4 -0.3 1.8 -1.7 1.1 -1.4 -1.7 -1.4 -0.7 -1.5 -0.7 -2.0 -1.6 -0.7 -1.5 -0.5 -0.8 -1.4
Had other major operations 0.5 0.7 3.0 0.6 0.2 0.6 -0.1 -0.3 1.1 -0.6 0.1 -1.7 -0.1 0.7 0.9 0.7 1.2 -0.1 0.8 -0.7 0.5 0.9 0.4 1.3 1.4 0.5
Forced vital capacity (FVC) 1.6 6.0 15.4 -2.4 1.2 -1.9 -3.9 3.5 -2.1 0.2 -1.1 -0.3 -1.5 -1.3 -2.9 -2.5 -2.5 -3.2 -2.9 -3.2 -3.6 -2.6 -2.3 -2.4 0.9 -3.0
Heel bone mineral density (BMD) T-score, automated (right) 3.4 7.9 27.1 0.3 -5.2 -0.7 4.3 1.4 1.0 -4.9 4.9 -4.0 5.2 -2.5 -2.3 -1.5 0.3 -0.6 0.6 -1.6 -1.4 0.8 -1.6 0.6 -4.4 -0.4
Ever unenthusiastic/disinterested for a whole week 1.1 1.3 4.1 0.8 0.5 0.9 -0.5 -0.1 1.5 -0.2 -0.8 -1.6 -0.5 1.5 0.2 1.3 2.0 0.6 1.5 -0.1 1.0 1.3 0.9 2.0 2.0 1.1
Qualifications: None of the above 2.6 5.6 16.5 1.6 2.5 1.4 -1.5 -3.2 1.5 2.1 -2.2 1.6 -2.2 2.9 4.1 2.8 1.9 2.4 1.9 2.7 2.9 1.7 2.6 1.7 2.8 2.3
Financial difficulties in last 2 years 1.5 2.1 7.0 1.9 1.0 -0.8 -0.7 -0.8 0.9 0.3 -0.9 -0.2 -0.7 2.6 1.4 2.0 1.8 1.4 1.4 0.9 1.7 1.1 2.0 1.7 1.9 1.9
Mouth/teeth dental problems 2.1 3.2 8.6 -2.4 -2.2 -0.5 1.5 2.1 -1.6 -1.6 1.6 -0.7 1.8 -2.1 -2.9 -2.2 -1.6 -1.4 -1.4 -1.5 -1.5 -1.7 -1.8 -1.4 -2.5 -1.5
Heart attack 2.6 3.3 10.0 2.7 -1.4 0.5 3.2 -1.1 2.6 -1.4 1.6 -3.1 1.6 0.6 1.0 1.6 2.5 0.9 2.0 -0.2 0.9 2.3 1.3 2.5 0.8 1.8
Allergy 2.4 5.4 9.8 1.9 1.4 -0.3 0.6 -2.5 2.8 0.6 -2.1 0.3 -1.4 3.1 2.9 3.0 2.8 2.7 2.8 2.3 2.5 2.8 2.7 2.6 2.8 2.7
Pain all over the body in last month 0.6 0.6 2.1 0.3 1.2 -0.2 -1.0 0.9 0.2 0.2 -0.8 -1.4 -1.1 0.8 0.8 0.0 0.4 -0.8 -0.2 -1.3 -0.6 -0.2 -0.5 0.4 1.4 -0.4
Diabetes (self-reported) 0.2 0.4 3.2 -0.1 -0.9 -1.8 0.1 0.3 0.2 -0.8 0.8 -0.2 1.1 -0.3 -0.7 0.0 0.2 0.2 0.3 0.0 0.2 0.2 0.2 0.3 -0.5 0.2
Hayfever/allergic rhinitis (self-reported) 1.9 2.5 7.1 -2.1 -1.5 0.9 -0.9 1.4 -1.4 -0.3 2.6 0.7 1.4 -2.7 -1.6 -1.8 -1.8 -1.2 -1.4 -0.6 -0.6 -1.5 -1.2 -1.7 -2.5 -1.4
Medication: Ramipril 1.1 1.5 3.2 1.5 0.1 1.2 1.4 -1.2 1.4 0.1 0.3 0.2 0.3 0.8 0.8 1.7 1.5 1.2 1.4 0.9 1.6 1.3 1.8 1.5 1.2 1.7
Medication: Simvastatin 0.2 0.2 1.0 0.8 0.8 1.0 0.5 0.1 -0.3 0.9 -0.3 1.0 -0.7 -0.2 0.0 0.0 -0.2 -0.1 -0.3 0.2 0.5 -0.2 0.1 -0.2 0.3 0.0
Fluid intelligence score 2.2 4.5 15.7 0.7 -3.6 -1.4 2.9 -0.1 2.4 -3.4 3.4 -3.4 4.0 -1.0 -1.4 0.4 1.9 0.5 1.7 -0.7 0.2 2.1 0.3 2.1 -1.8 1.1
Illnesses of siblings 1.4 2.0 12.0 -1.0 1.9 3.5 -1.8 -0.3 -0.2 3.1 -1.5 2.1 -2.1 0.8 0.5 0.3 -0.2 0.1 -0.1 0.6 0.7 -0.1 0.3 -0.3 1.6 -0.0
Neuroticism score 0.9 2.0 8.2 1.6 1.5 1.5 1.6 -1.2 1.3 0.8 -1.2 -1.7 -1.2 2.9 1.2 1.3 1.7 0.0 0.9 -0.7 0.1 1.0 0.6 1.7 2.5 0.7
Weight 4.6 22.7 81.4 -3.1 -6.1 -6.8 -0.7 8.1 -0.7 -6.5 5.7 -4.9 6.3 -5.2 -9.0 -4.1 -1.5 -3.6 -1.6 -4.5 -3.4 -1.3 -3.5 -0.6 -5.1 -2.8
Impedance of arm (right) 1.2 5.4 24.8 0.7 3.9 5.0 -0.1 -0.4 -0.6 3.8 -3.6 0.4 -4.1 3.1 1.3 -0.1 -0.4 -1.6 -1.3 -1.6 -1.3 -1.1 -0.6 -0.7 3.9 -1.2
Arm fat percentage (right) 1.9 7.7 18.2 4.3 -0.8 -0.9 2.3 -2.1 3.8 -2.1 0.6 -2.9 1.4 3.1 2.4 3.3 3.8 2.4 3.5 1.3 2.7 3.5 2.8 3.9 1.7 3.3
Trunk fat-free mass 14.2 81.4 269.0 -9.3 -8.3 -9.2 -3.6 15.1 -5.6 -7.6 8.2 -4.8 7.9 -11.4 -16.4 -10.1 -7.0 -8.7 -6.7 -8.9 -8.7 -6.3 -9.1 -5.7 -10.0 -8.4
Hip circumference 2.8 12.1 38.9 -0.8 -5.6 -5.2 0.7 4.9 1.3 -6.2 4.9 -4.6 5.9 -2.8 -5.9 -1.6 0.8 -1.1 0.9 -2.2 -1.0 0.9 -1.3 1.5 -3.7 -0.4
Time employed in main current job 0.1 0.2 0.8 -0.2 -0.7 0.5 -0.4 0.3 0.2 -0.9 0.4 -0.5 0.5 -0.2 -0.6 -0.3 0.3 -0.1 0.2 -0.3 -0.1 0.2 -0.2 0.3 -0.2 -0.2
Alcohol intake versus 10 years previously 0.9 1.3 4.1 -1.1 1.9 -1.5 -2.0 1.5 -0.7 1.9 -1.4 0.8 -1.8 0.7 -1.0 -0.2 -1.0 -0.7 -0.8 -0.4 -0.2 -0.7 -0.7 -1.0 0.5 -0.8
Father’s age at death 1.0 1.4 3.9 -1.6 -0.3 -0.1 1.1 0.9 -2.0 0.0 -0.2 0.9 0.3 -1.4 -1.8 -1.4 -1.6 -0.5 -1.3 -0.2 -0.8 -1.7 -1.1 -1.6 -1.6 -1.0
Worrier / anxious feelings 1.2 2.3 8.3 -1.3 0.7 2.2 1.0 1.1 -1.1 1.2 0.2 -1.6 -0.7 -0.4 -1.0 -1.5 -1.1 -2.4 -1.6 -2.9 -2.2 -1.5 -2.1 -1.2 0.2 -1.9
Frequency of tiredness / lethargy in last 2 weeks 1.8 2.9 14.2 2.0 -1.6 -1.3 2.0 -0.2 2.0 -3.2 1.6 -3.8 2.2 1.0 0.2 0.9 2.1 0.1 1.6 -1.1 0.2 1.7 0.2 2.4 0.1 0.8
Falls in the last year 0.1 0.1 1.0 0.4 0.2 -0.3 1.0 -0.3 0.0 0.1 -0.1 -0.2 0.1 0.0 0.0 0.1 -0.0 -0.1 -0.1 -0.2 -0.2 0.0 -0.1 -0.1 -0.0 -0.1
Hair/balding pattern: Pattern 3 4.6 6.8 17.2 -2.0 -3.3 -1.8 1.4 3.0 -1.9 -2.1 3.3 -1.2 3.1 -4.1 -3.7 -3.0 -2.3 -2.1 -2.0 -1.9 -2.1 -1.8 -2.6 -2.0 -4.2 -2.2
Number of live births 0.4 0.6 2.4 0.1 0.7 0.3 -1.6 -0.3 0.9 0.4 -0.7 0.3 -0.6 1.2 0.9 0.8 0.6 0.8 0.8 0.8 0.7 0.8 0.7 0.6 0.9 0.5
Forced expiratory volume in 1-second (FEV1) 1.5 5.0 11.9 -2.2 1.0 -2.3 -3.4 3.0 -1.7 -0.2 -1.0 -0.6 -1.1 -1.5 -2.4 -2.2 -2.1 -3.1 -2.7 -3.2 -3.3 -2.3 -2.1 -2.0 1.0 -2.7
Pulse rate 2.2 3.8 14.1 -0.8 3.3 -0.2 -3.6 -0.5 -1.4 3.5 -2.7 2.1 -3.8 1.1 2.5 -0.0 -1.1 -0.7 -1.4 0.1 -0.1 -1.3 -0.0 -1.4 2.5 -0.8
Happiness 1.5 1.8 4.6 2.1 0.2 1.1 1.5 -1.0 1.6 0.5 -0.0 -0.2 -0.3 2.1 0.6 1.8 1.6 1.1 1.4 0.9 1.9 1.5 1.6 1.6 1.2 1.7
Noisy workplace 0.5 0.6 2.6 0.3 1.4 0.6 0.4 0.2 -0.5 0.8 -1.6 -1.0 -1.5 1.0 0.3 -0.1 -0.3 -0.7 -0.5 -1.0 -0.7 -0.5 -0.7 -0.4 0.9 -0.5
Qualifications: A levels/AS levels or equivalent 2.3 5.2 14.5 -0.1 -3.7 -2.0 0.8 3.0 0.1 -3.8 3.0 -2.7 3.7 -2.6 -3.8 -1.9 -0.4 -1.5 -0.6 -1.9 -1.9 -0.3 -1.6 -0.1 -3.0 -1.1
Serious illness, injury or assault of a close relative in last 2 years 0.1 0.1 0.5 -0.3 0.4 0.4 0.6 -0.1 -0.2 0.7 -0.1 0.5 -0.1 0.1 -0.4 -0.0 -0.0 -0.1 -0.1 0.1 0.2 -0.2 -0.2 -0.0 -0.0 -0.1
Mouth/teeth dental problems: Dentures 0.7 1.2 6.7 -1.2 1.1 -0.9 -2.6 1.2 -1.2 1.5 -0.5 1.4 -1.3 -0.9 -0.1 -0.8 -1.0 -0.8 -1.0 -0.0 -0.2 -1.0 -0.8 -1.0 0.0 -1.0
Asthma 0.3 0.6 1.8 -1.1 0.3 -0.8 0.4 0.5 -0.7 0.7 0.4 -0.1 -0.1 -0.5 -1.3 -1.0 -0.8 -1.0 -0.8 -0.8 -1.2 -0.7 -1.1 -0.7 -0.4 -1.0
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.4 2.5 1.3 0.3 1.6 0.8 -0.4 0.5 -0.4 -0.1 -0.4 -0.1 0.6 0.4 0.6 0.7 0.1 0.3 -0.2 -0.1 0.4 0.3 0.6 0.8 0.4
Medication: Cholesterol lowering 0.6 0.9 4.7 2.2 0.9 0.1 0.6 -1.1 1.0 0.2 -1.1 0.4 -0.7 0.8 1.0 1.2 1.0 0.8 0.7 0.9 0.8 1.0 1.1 0.9 1.2 1.0
Depression (self-reported) 5.5 6.6 12.5 3.0 2.0 1.5 -0.0 -2.9 1.6 1.5 -1.8 1.7 -1.4 3.5 2.9 3.3 2.8 3.1 2.5 3.1 2.8 2.0 3.3 2.6 3.2 3.0
Medication: Lansoprazole 1.4 1.5 5.6 1.5 1.3 1.2 1.5 -1.7 0.8 0.7 -1.2 -1.0 -1.1 1.5 2.4 1.4 1.2 0.4 0.6 -0.2 0.4 0.6 1.0 1.0 2.4 0.9
Prospective memory result 0.4 0.5 1.9 -0.4 0.9 0.5 -1.4 0.6 -1.2 0.8 -0.3 0.5 -0.7 -0.4 0.5 -0.1 -0.7 -0.7 -1.0 -0.4 0.1 -1.1 -0.0 -0.7 0.6 -0.5
Lung cancer (father) 2.3 2.7 7.3 -1.5 0.0 0.4 -1.2 2.4 -1.9 0.2 0.4 -0.5 -0.1 -1.7 -2.7 -1.9 -1.8 -2.1 -1.9 -1.9 -1.8 -2.0 -2.0 -1.8 -1.0 -2.0
Illnesses of mother 0.6 0.7 5.3 -1.7 0.7 0.4 -2.3 0.3 -0.6 1.6 -0.4 1.1 -1.2 0.1 0.0 -0.4 -0.5 -0.2 -0.4 -0.0 -0.4 -0.6 -0.0 -0.5 0.7 -0.5
Forced expiratory volume in 1-second (FEV1), Best measure 2.1 6.6 18.2 -2.6 1.4 -2.0 -4.3 3.4 -2.1 0.4 -1.1 -0.4 -1.4 -2.1 -2.7 -2.6 -2.6 -3.6 -3.1 -3.5 -3.4 -2.7 -2.7 -2.5 0.5 -3.3
Pulse wave Arterial Stiffness index 1.1 1.3 5.2 0.2 -2.0 0.6 1.3 0.9 0.7 -1.5 2.2 -1.6 2.3 -1.3 -1.3 -0.3 0.3 -0.3 0.3 -0.6 0.2 0.5 -0.3 0.5 -1.5 0.1
Impedance of arm (left) 1.2 5.4 20.2 0.7 4.1 4.5 -0.0 -0.9 -0.3 3.9 -3.9 0.7 -4.3 3.0 1.8 0.3 -0.2 -1.3 -1.1 -1.3 -1.0 -0.8 -0.3 -0.6 4.1 -0.9
Arm fat mass (right) 1.3 5.2 18.4 1.6 -3.3 -3.5 1.1 1.9 2.3 -4.3 3.0 -3.8 3.8 -0.2 -2.1 0.6 2.0 0.4 1.9 -0.7 0.7 2.0 0.6 2.4 -1.3 1.3
Trunk predicted mass 14.1 80.7 269.0 -9.3 -8.2 -9.2 -3.7 15.0 -5.6 -7.5 8.1 -4.7 7.8 -11.3 -16.4 -10.1 -7.0 -8.6 -6.7 -8.8 -8.7 -6.4 -9.0 -5.8 -9.9 -8.4
Standing height 17.9 177.4 574.4 -14.5 -9.3 -9.3 -6.2 22.6 -9.3 -7.8 9.6 -6.4 8.3 -15.8 -24.0 -15.9 -11.6 -15.0 -11.9 -15.2 -14.8 -10.9 -14.6 -9.9 -11.9 -14.3
Length of working week for main job 0.2 0.3 2.0 -0.8 -0.5 -1.4 0.3 0.4 -0.2 0.0 0.4 0.5 0.7 -0.6 -0.6 -0.4 -0.2 0.0 0.1 0.3 0.2 0.0 -0.3 -0.1 -0.9 -0.1
Exposure to tobacco smoke at home 0.9 1.0 4.3 -0.3 2.1 -0.2 0.1 -0.6 -0.7 1.9 -1.4 0.7 -1.9 1.6 1.0 0.2 -0.4 -0.4 -0.6 -0.2 -0.0 -0.7 -0.0 -0.6 1.4 -0.3
Breastfed as a baby 1.2 1.4 8.3 -0.1 1.9 2.1 0.7 -1.2 -0.4 2.9 -1.0 1.4 -2.0 0.9 1.6 0.6 -0.2 -0.1 -0.5 0.2 0.2 -0.4 0.4 -0.4 1.7 0.1
Tense / ‘highly strung’ 0.9 1.4 6.9 0.8 2.1 1.2 0.5 -0.2 0.7 1.5 -1.8 -1.2 -1.8 2.6 0.2 0.4 0.7 -0.8 0.0 -1.2 -0.6 0.3 -0.5 0.7 2.1 -0.3
Seen doctor (GP) for nerves, anxiety, tension or depression 0.9 1.3 3.8 1.7 -0.9 -0.4 1.2 -0.9 1.6 -1.2 1.1 -1.8 1.1 1.0 0.5 0.9 1.8 0.4 1.2 -0.2 0.4 1.4 0.8 2.0 0.5 0.9
Hair/balding pattern: Pattern 4 3.4 8.2 19.0 -0.8 -4.1 -0.2 1.9 3.4 -0.6 -4.2 3.9 -4.4 3.9 -3.5 -2.9 -2.8 -0.9 -2.5 -1.0 -3.6 -2.6 -1.0 -3.2 -0.6 -4.1 -2.1
Birth weight of first child 0.5 1.0 5.8 0.6 1.5 1.5 -0.5 0.0 0.9 0.5 -1.5 -0.9 -1.3 1.2 -0.1 0.6 0.9 -0.5 0.1 -1.0 -0.4 0.5 0.1 0.9 2.4 -0.1
Peak expiratory flow (PEF) 4.4 10.2 32.6 -3.1 -1.4 -2.2 -2.0 5.5 -1.8 -2.0 1.5 -2.3 1.3 -3.2 -5.7 -3.7 -2.3 -4.1 -3.0 -4.6 -4.4 -2.7 -3.5 -1.9 -1.2 -3.7
Pulse wave reflection index 1.5 1.9 7.9 -0.1 -2.5 -1.1 1.8 0.8 0.1 -1.8 2.3 -1.1 2.8 -1.6 -2.1 -0.5 -0.0 0.0 0.3 -0.2 0.2 0.2 -0.3 0.2 -2.4 0.1
Ever highly irritable/argumentative for 2 days 0.8 1.0 6.3 0.5 1.7 -0.1 0.5 -0.7 0.7 0.7 -2.3 -0.5 -1.3 1.1 0.6 0.9 0.7 -0.1 0.2 -0.4 0.3 0.3 0.8 0.7 2.5 0.3
Loud music exposure frequency 1.3 1.4 5.2 0.7 2.1 1.8 -1.1 0.3 -0.1 1.6 -1.2 -0.9 -2.1 1.8 1.0 0.2 0.2 -0.8 -0.4 -1.2 -1.0 -0.4 -0.3 0.0 2.3 -0.4
Qualifications: O levels/GCSEs or equivalent 0.6 0.9 3.2 0.1 -1.3 -1.3 0.8 1.4 0.6 -1.8 1.1 -1.6 1.4 -0.4 -1.5 -0.2 0.5 -0.0 0.5 -0.6 -0.8 0.5 -0.4 0.7 -0.6 0.0
Mouth/teeth dental problems: Bleeding gums 4.5 5.8 12.8 3.6 0.6 0.3 1.4 -2.9 3.0 -0.2 -1.1 -0.5 -0.3 3.0 2.8 3.2 2.9 2.6 2.7 2.0 2.1 2.9 3.1 2.8 2.7 2.9
Blood clot in the leg (DVT) 13.8 17.8 31.5 -4.9 -1.7 -1.0 -3.1 4.5 -5.6 0.1 2.7 0.2 1.1 -5.6 -3.9 -5.5 -5.2 -4.7 -5.3 -3.9 -4.6 -5.6 -4.7 -5.0 -4.3 -5.0
Medication: Paracetamol 1.0 1.6 4.7 2.2 0.0 -0.3 1.0 -1.4 1.5 -0.3 0.1 -0.3 0.3 1.2 1.5 1.8 1.4 1.5 1.5 1.2 1.5 1.6 1.7 1.3 0.8 1.7
Headache pain in last month 0.2 0.4 1.9 -0.3 0.7 -1.4 -0.7 -0.5 -0.1 0.7 -0.6 1.3 -0.5 0.1 0.4 0.4 0.1 0.2 0.0 0.6 0.9 -0.0 0.5 0.1 0.5 0.3
Medication for cholesterol, blood pressure or diabetes 0.7 1.1 2.1 -1.3 -0.8 1.3 -0.4 1.3 -1.1 -0.1 1.1 -0.7 0.5 -0.8 -1.2 -1.4 -0.9 -1.1 -0.9 -1.2 -1.4 -1.1 -1.4 -0.8 -1.1 -1.2
Glaucoma (self-reported) 0.4 0.4 2.6 0.0 -0.2 -1.0 -1.5 -0.7 -0.3 -0.2 -0.5 1.6 0.1 -0.4 0.5 0.1 -0.4 0.7 0.0 1.1 0.2 -0.0 0.6 -0.4 -0.5 0.3
Gout (self-reported) 0.3 0.4 1.1 -0.3 0.3 0.7 0.3 0.1 -0.4 0.3 -0.2 -0.1 -0.3 -0.6 -0.1 -0.8 -0.9 -0.9 -0.8 -0.8 -1.1 -0.6 -1.0 -0.9 -0.3 -1.0
Hypothyroidism/myxoedema (self-reported) 0.2 0.4 6.5 0.2 0.5 -2.5 -1.0 0.5 -0.4 0.3 -0.2 0.2 -0.1 0.3 -0.8 0.2 -0.2 0.2 -0.1 0.3 0.1 -0.1 0.3 -0.2 0.0 0.1
Medication: Amlodipine 0.5 0.7 2.6 -0.2 1.6 0.6 -0.7 -0.4 -0.4 1.6 -1.0 1.5 -1.3 1.1 0.5 0.4 -0.5 0.4 -0.1 0.7 0.2 -0.2 0.5 -0.5 1.1 0.1
Medication: Ventolin 100micrograms inhaler 0.3 0.4 1.7 -0.5 1.2 -1.3 0.3 -0.0 -0.6 1.1 -0.3 0.4 -1.0 0.5 -0.1 -0.2 -0.5 -0.5 -0.6 -0.3 -0.4 -0.6 -0.4 -0.6 0.5 -0.4
Birth weight 2.7 5.8 12.4 -2.3 0.6 -1.1 -1.6 3.2 -2.3 0.8 -0.6 -0.3 -0.9 -2.6 -3.1 -2.7 -2.7 -3.5 -3.3 -3.3 -3.2 -2.8 -2.3 -2.7 0.4 -3.2
Chronic bronchitis/emphysema (mother) 1.2 1.4 4.8 1.1 1.6 0.0 -1.5 -1.5 0.1 1.5 -1.6 1.3 -1.7 0.9 2.2 1.2 0.4 0.4 0.1 0.9 1.4 0.2 1.2 0.2 1.7 0.7
High blood pressure (siblings) 1.8 2.6 12.7 0.7 -2.9 -3.6 1.6 -0.2 0.5 -3.0 2.3 -1.1 2.8 -1.6 -0.4 -0.1 0.3 0.7 0.7 0.6 0.2 0.7 0.2 0.5 -2.6 0.6
Forced vital capacity (FVC), Best measure 2.0 7.3 18.7 -2.5 1.4 -1.8 -4.3 3.9 -2.2 0.4 -1.2 -0.4 -1.6 -1.9 -3.3 -2.8 -2.7 -3.7 -3.2 -3.6 -3.6 -2.8 -2.8 -2.6 0.7 -3.4
Body fat percentage 2.3 9.2 19.2 4.3 -1.1 -0.2 2.6 -2.5 4.3 -2.4 0.8 -3.0 1.8 2.8 2.6 3.5 4.3 2.7 3.9 1.5 3.0 4.0 3.2 4.4 1.8 3.6
Leg fat percentage (right) 5.1 18.6 36.2 6.0 -1.2 0.4 4.0 -5.4 5.4 -2.6 0.8 -2.3 2.1 3.7 5.1 5.2 5.6 4.7 5.4 3.5 4.8 5.4 4.8 5.5 1.9 5.4
Arm fat-free mass (right) 10.5 53.8 174.2 -7.4 -7.6 -8.6 -2.9 12.0 -3.7 -7.2 7.5 -4.6 7.5 -9.8 -13.2 -7.8 -4.9 -6.5 -4.6 -6.8 -6.4 -4.4 -6.9 -3.8 -8.6 -6.2
Exposure to tobacco smoke outside home 0.6 0.8 4.0 1.0 1.1 -0.4 1.1 -0.5 0.8 0.7 -1.0 -0.7 -0.8 2.0 0.7 1.1 1.0 0.3 0.7 0.0 0.6 0.7 0.6 0.9 1.4 0.7
Comparative body size at age 10 0.7 2.0 14.3 2.6 -0.8 -3.8 0.4 -1.1 1.3 -2.0 0.1 -1.2 1.1 0.5 1.7 1.2 1.1 1.0 1.0 0.6 0.5 1.2 1.2 1.2 0.1 1.2
Number of full brothers 3.1 3.9 10.0 -2.6 1.2 -0.6 -3.2 1.8 -2.5 1.2 -0.6 0.8 -1.2 -1.2 -0.4 -2.1 -2.7 -2.2 -2.5 -1.8 -2.1 -2.6 -2.3 -2.7 -0.6 -2.6
Worry too long after embarrassment 0.7 1.2 4.5 1.9 0.6 1.7 2.1 -0.4 1.2 0.1 -0.9 -1.8 -0.5 1.7 0.2 0.6 1.3 -0.3 0.6 -0.9 -0.7 0.9 -0.1 1.2 1.4 0.3
Seen a psychiatrist for nerves, anxiety, tension or depression 1.2 1.6 3.9 1.8 1.6 -0.8 -1.2 -0.9 0.6 0.5 -1.6 0.9 -1.2 2.0 1.3 1.6 0.9 1.2 0.8 1.3 0.9 0.8 1.6 0.8 1.9 1.2
Wheeze or whistling in the chest in last year 0.3 0.6 3.0 -1.2 1.0 -0.6 -0.3 0.3 -0.9 1.7 -0.2 1.1 -1.0 -0.1 -0.8 -0.4 -0.9 -0.4 -0.6 0.2 0.1 -0.7 -0.5 -0.9 -0.2 -0.5
Number of children fathered 0.3 0.4 2.5 0.8 -0.6 0.7 1.6 -0.2 0.6 -0.9 0.3 -0.9 0.8 -0.5 -0.7 -0.0 0.4 -0.1 0.3 -0.5 -0.3 0.4 -0.0 0.5 0.0 0.1
Reason for reducing amount of alcohol drunk: Health precaution 3.1 3.6 8.4 -0.5 -2.1 -0.1 1.6 1.7 -1.7 -1.2 2.9 -2.1 1.8 -2.2 -2.1 -2.3 -1.4 -2.1 -1.8 -2.3 -2.2 -1.8 -2.2 -1.3 -2.4 -1.8
Age at first live birth 0.8 1.5 6.5 0.3 -2.6 -0.4 1.7 0.4 1.0 -2.1 2.0 -1.3 2.2 -1.6 -1.2 -0.3 0.3 0.1 0.4 -0.3 -0.4 0.9 -0.0 0.5 -1.6 0.2
Pulse wave peak to peak time 0.7 0.8 2.3 -0.8 1.1 -1.1 -1.4 0.5 -1.0 0.8 -1.4 0.9 -1.5 0.4 -0.3 -0.6 -0.8 -0.6 -0.9 -0.4 -1.0 -1.0 -0.5 -0.9 0.7 -0.8
Health satisfaction 0.7 0.8 4.5 0.9 -1.3 -0.0 1.6 0.3 0.8 -0.9 1.6 -2.1 1.4 -0.1 -0.5 0.2 0.7 -0.5 0.5 -0.9 0.7 0.5 0.2 0.9 -0.3 0.5
Shortness of breath walking on level ground 1.8 2.2 5.0 1.6 1.0 -1.2 -0.3 -1.3 1.8 0.4 -1.0 -0.5 -0.7 2.2 1.5 2.0 1.7 1.3 1.6 1.2 2.2 1.8 1.6 1.6 1.6 1.7
Qualifications: College or University degree 4.1 12.9 34.4 -2.5 -4.5 -1.7 0.8 4.1 -2.6 -2.8 4.5 -1.1 4.0 -5.3 -5.5 -4.3 -3.3 -2.9 -2.9 -2.7 -3.5 -2.7 -3.7 -2.9 -5.9 -3.1
Eye problems/disorders: None of the above 0.3 0.4 1.9 -0.8 0.5 1.4 -0.4 1.0 -0.7 0.9 -0.3 -0.1 -0.4 0.1 -0.8 -0.5 -0.3 -0.4 -0.3 -0.4 -0.3 -0.6 -0.7 -0.3 0.0 -0.5
Mouth/teeth dental problems: Loose teeth 0.5 0.6 2.1 0.1 -1.4 0.9 0.1 0.7 -0.1 -0.8 1.5 -0.7 1.2 -1.0 -1.4 -0.5 -0.2 -0.1 -0.0 -0.1 -0.2 -0.0 -0.4 -0.0 -1.3 -0.1
Emphysema/chronic bronchitis 0.5 0.6 2.6 0.2 1.6 0.5 -0.7 -0.1 -0.8 0.9 -1.5 0.4 -1.6 0.7 0.9 0.2 -0.3 -0.2 -0.5 -0.1 -0.1 -0.6 -0.1 -0.4 1.0 -0.2
Medication for pain relief, constipation, heartburn 1.5 2.6 10.8 -3.3 -1.0 -0.4 -1.0 1.7 -1.8 -0.2 0.8 0.5 0.6 -2.0 -2.0 -2.1 -1.8 -1.4 -1.6 -1.0 -1.4 -1.8 -1.6 -1.7 -1.6 -1.8
Neck or shoulder pain in last month 1.1 1.5 5.5 -0.0 -1.7 -0.2 1.5 1.3 0.5 -2.0 2.0 -2.3 1.9 -0.8 -1.5 -0.7 0.1 -1.0 -0.1 -1.6 -0.9 0.2 -1.0 0.3 -1.3 -0.6
Medication: Blood pressure 0.9 1.5 4.9 1.2 -0.3 -2.2 0.8 -1.2 1.3 -0.7 0.2 0.5 0.7 1.0 0.7 1.5 1.2 1.5 1.3 1.5 1.8 1.5 1.7 1.2 0.4 1.6
Angina (self-reported) 1.7 2.2 4.9 1.8 -1.1 -0.1 1.3 -0.7 2.2 -1.6 1.2 -1.9 1.3 0.5 0.6 1.6 2.1 1.3 2.1 0.6 1.6 2.1 1.3 2.2 0.3 1.8
Migraine (self-reported) 0.9 1.1 3.1 0.1 0.9 -1.4 -0.9 -1.5 0.6 0.7 -0.9 1.6 -0.8 1.1 1.2 1.2 0.7 1.5 1.0 1.8 1.1 0.8 1.2 0.6 0.9 1.0
Medication: Ibuprofen 0.1 0.1 1.0 0.7 -0.1 1.0 0.7 0.1 0.2 -0.5 0.2 -0.4 0.0 0.3 -0.0 0.1 0.4 -0.1 0.1 -0.4 -0.3 0.1 0.1 0.4 0.4 0.1
Medication: Allopurinol 0.1 0.1 0.3 0.6 0.2 -0.1 0.1 -0.2 0.3 -0.1 -0.2 -0.5 -0.1 -0.0 0.3 -0.2 -0.3 -0.4 -0.2 -0.5 -0.5 0.1 -0.4 -0.2 0.0 -0.4
Medication: Omeprazole 0.1 0.1 0.7 0.6 -0.1 -0.3 0.8 -0.8 0.2 0.6 0.2 0.1 -0.1 -0.5 0.1 -0.2 -0.1 -0.3 -0.1 0.0 0.2 0.1 -0.2 -0.1 -0.1 -0.0
Medication: Seretide 50 evohaler 0.6 0.6 1.8 -1.3 -0.1 -0.1 0.5 0.3 -1.3 1.0 1.2 0.7 0.1 -0.9 -0.8 -0.9 -0.9 -0.5 -0.9 -0.2 -0.4 -1.1 -0.7 -0.9 -0.8 -0.8
Mean time to correctly identify matches 0.6 1.2 3.8 2.0 -0.5 0.6 0.6 -0.7 0.7 -0.2 0.4 -0.2 0.3 1.2 1.0 1.2 1.3 1.4 1.3 1.4 1.7 1.1 1.2 1.2 0.0 1.5
Heart disease (mother) 1.1 1.3 6.2 2.5 -0.8 -2.2 1.3 0.1 1.0 -2.1 0.2 -2.1 1.0 0.6 0.6 0.5 1.1 0.1 0.7 -0.5 -0.1 0.8 0.4 1.2 0.2 0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.2 0.3 2.9 -0.6 0.2 -0.1 -1.7 0.4 -0.4 0.4 0.2 0.6 -0.4 -0.5 0.3 -0.4 -0.5 -0.2 -0.4 0.1 -0.2 -0.4 -0.3 -0.5 -0.3 -0.4
Whole body fat mass 1.2 4.9 17.5 1.2 -3.2 -3.0 1.0 2.2 2.2 -4.2 2.9 -3.9 3.8 -0.7 -2.5 0.3 1.8 -0.0 1.6 -1.1 0.3 1.8 0.2 2.2 -1.2 0.9
Leg fat mass (right) 1.8 6.8 20.1 2.8 -3.3 -2.7 2.2 -0.0 3.3 -4.5 2.8 -3.5 4.0 0.3 -0.5 1.8 3.0 1.7 3.0 0.6 1.8 3.1 1.7 3.3 -1.0 2.4
Arm predicted mass (right) 10.2 52.0 170.0 -7.3 -7.5 -8.6 -2.9 11.9 -3.7 -7.1 7.4 -4.3 7.4 -9.5 -13.0 -7.6 -4.9 -6.3 -4.5 -6.6 -6.3 -4.3 -6.7 -3.8 -8.5 -6.0
Pulse rate, automated reading 1.7 5.6 22.1 -1.6 4.4 -0.6 -3.0 -0.8 -1.6 4.7 -3.6 2.9 -4.7 1.8 2.4 0.0 -1.2 -0.7 -1.5 0.5 0.3 -1.5 0.0 -1.5 3.2 -0.9
Alcohol intake frequency. 0.5 1.1 3.9 0.5 2.0 -0.0 0.9 -0.9 0.5 1.5 -1.6 0.1 -1.8 1.9 1.2 1.1 0.6 0.1 0.2 0.0 0.6 0.4 0.5 0.4 2.0 0.4
Comparative height size at age 10 11.0 60.7 234.1 -6.9 -6.1 -7.0 -3.0 14.9 -4.0 -6.2 5.8 -6.2 5.6 -7.8 -15.3 -8.6 -5.3 -8.8 -6.0 -9.7 -8.5 -5.2 -7.8 -4.2 -5.7 -7.7
Number of full sisters 0.9 1.1 2.9 1.6 0.2 -1.5 1.1 -1.3 0.8 -0.7 -0.2 -0.4 0.1 1.6 1.7 1.3 1.1 1.0 0.8 0.8 1.1 0.8 1.2 1.0 0.6 1.2
Suffer from ‘nerves’ 0.2 0.3 0.9 0.0 0.7 0.8 0.6 -0.1 0.1 0.7 0.1 -0.6 -0.4 0.8 0.1 -0.1 0.2 -0.7 -0.2 -0.9 -0.5 -0.2 -0.5 0.1 0.8 -0.4
Overall health rating 0.9 2.0 7.1 2.7 0.2 -0.3 1.7 -0.9 1.8 -0.2 0.2 -2.2 0.1 1.9 1.7 1.6 1.8 0.5 1.4 -0.1 1.2 1.6 1.0 1.8 1.2 1.4
Chest pain or discomfort 0.4 0.5 2.4 0.3 -0.8 -0.5 1.4 0.4 0.2 -0.5 1.5 -1.6 0.8 -0.2 -0.5 -0.5 0.5 -0.7 -0.0 -1.0 -0.5 0.0 -0.5 0.6 -0.2 -0.2
Had major operations 1.0 1.1 3.5 0.7 1.7 -1.3 -0.6 -1.2 0.3 1.4 -1.7 0.9 -1.9 0.9 1.9 0.8 0.5 0.2 0.1 0.5 0.7 0.2 0.6 0.3 1.9 0.4
Age at last live birth 0.5 0.8 3.4 -0.2 -1.8 -0.8 0.3 1.1 0.2 -1.3 1.5 -0.6 1.5 -1.1 -1.5 -0.6 0.0 0.0 0.1 -0.0 -0.4 0.3 -0.3 0.1 -1.6 -0.1
Family relationship satisfaction 0.8 1.0 2.8 1.2 -1.7 -0.5 1.2 0.3 0.3 -1.3 1.4 -0.7 1.5 0.3 -0.9 0.6 1.1 1.0 0.9 0.8 1.1 0.6 0.9 1.1 -1.0 1.3
Leg pain on walking 0.8 1.0 4.9 0.8 2.1 0.4 -1.0 -0.8 -0.1 1.5 -2.2 0.2 -1.8 1.1 0.7 0.7 -0.0 -0.3 -0.4 -0.2 0.2 -0.2 0.3 -0.2 1.9 0.0
Qualifications: NVQ or HND or HNC or equivalent 1.1 1.4 7.9 0.3 2.2 -1.4 -0.6 -0.1 -0.0 1.1 -2.8 0.2 -2.4 1.7 1.0 0.5 0.1 -0.4 -0.3 -0.3 0.1 -0.1 0.2 -0.0 2.3 -0.1
Commuting to job workplace: Car/motor vehicle 0.9 1.0 3.0 1.4 -1.0 1.5 0.8 -0.8 1.1 -1.1 1.1 -1.7 1.1 0.4 0.8 0.7 1.3 0.7 1.3 0.0 0.2 1.1 0.6 1.4 0.3 0.9
Illness, injury, bereavement, stress in last 2 years 0.9 1.0 4.3 0.5 -1.9 0.4 1.2 0.1 -0.3 -1.1 2.1 -0.1 1.6 -1.7 -0.8 -0.7 -0.9 -0.2 -0.6 0.1 -0.2 -0.2 -0.3 -0.8 -2.1 -0.2
Medication: Aspirin 1.9 2.5 11.4 3.4 -1.3 -0.1 1.8 -1.0 1.8 -1.7 1.3 -1.0 1.6 1.1 0.6 1.5 1.7 1.4 1.7 1.1 1.7 1.9 1.4 1.7 -0.6 1.9
Supplements: Vitamin C 0.5 0.6 4.1 -0.8 0.4 -1.4 -2.0 0.9 -0.6 -0.1 -0.0 -0.1 -0.2 -0.2 -0.6 -0.7 -0.5 -1.0 -0.7 -1.0 -0.8 -0.7 -0.7 -0.4 0.3 -1.0
Knee pain experienced in last month 5.6 8.6 31.9 3.8 3.7 3.1 0.3 -4.2 2.3 2.3 -3.5 -0.8 -3.1 4.0 5.7 3.2 2.6 1.4 2.0 0.8 1.6 2.1 1.9 2.3 4.2 2.0
Hypertension (Self-reported) 1.3 3.7 7.0 1.7 0.3 -2.4 0.4 -2.0 2.4 -0.7 -0.2 0.3 0.2 2.2 1.8 2.4 2.2 2.1 2.2 2.0 2.6 2.4 2.5 2.2 1.6 2.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.6 0.7 4.3 -0.1 0.9 1.0 0.4 0.2 -1.2 2.1 -0.4 0.6 -1.2 0.3 -0.1 -0.6 -1.0 -0.8 -1.1 -0.4 -0.4 -1.1 -0.6 -1.1 0.2 -0.6
Illnesses of father: Heart disease 2.3 3.2 10.7 3.3 -1.5 -0.3 2.2 -1.1 2.7 -2.8 1.1 -2.7 1.8 1.1 0.7 1.4 2.1 1.0 2.1 -0.0 0.3 2.3 1.0 2.3 0.2 1.5
Illnesses of siblings: Diabetes 1.3 1.6 6.7 0.4 -1.8 -2.1 1.6 0.6 0.5 -2.5 1.7 -2.6 1.9 -0.4 -1.0 -0.3 0.6 -0.1 0.5 -0.9 -0.9 0.3 -0.4 0.7 -1.0 0.0
Smoking status: Previous 2.4 3.7 12.8 0.9 3.6 1.6 -0.4 -2.2 -0.1 3.1 -3.5 2.0 -3.4 2.2 2.2 1.5 0.3 0.8 0.2 1.3 0.9 0.3 1.1 -0.0 2.9 0.7
Forced expiratory volume in 1-second (FEV1), predicted 8.1 16.9 51.9 -4.0 -2.7 -3.0 -3.8 7.2 -3.1 -2.7 3.4 -1.7 2.5 -4.5 -6.7 -4.8 -3.7 -4.7 -3.9 -4.6 -4.1 -3.6 -4.4 -3.1 -3.7 -4.4
Whole body fat-free mass 12.3 70.3 243.4 -8.5 -7.9 -9.1 -3.5 14.3 -4.9 -7.5 7.7 -4.8 7.6 -10.3 -15.6 -9.2 -6.2 -7.9 -5.9 -8.2 -7.8 -5.6 -8.2 -5.0 -9.2 -7.5
Leg fat-free mass (right) 10.1 53.7 193.2 -7.3 -6.6 -8.7 -3.6 13.1 -4.3 -6.4 6.3 -4.2 6.3 -8.4 -13.9 -8.0 -5.3 -6.9 -5.1 -7.1 -6.6 -5.0 -7.1 -4.2 -7.8 -6.5
Arm fat percentage (left) 2.1 8.5 18.6 4.3 -0.5 -1.2 2.3 -2.6 3.9 -2.0 0.1 -2.6 1.2 3.2 2.9 3.6 4.0 2.7 3.7 1.6 3.0 3.7 3.1 4.0 1.9 3.5
Average weekly red wine intake 1.0 1.5 5.2 0.7 -1.6 0.8 0.6 1.6 0.5 -2.2 1.9 -1.7 2.0 -1.2 -2.3 -0.5 -0.1 -0.6 -0.1 -1.4 -1.6 0.1 -0.5 0.1 -0.9 -0.4
Handedness (chirality/laterality): Left-handed 2.3 2.8 7.2 -1.4 0.6 0.8 0.3 1.3 -2.2 0.9 0.3 -0.7 -0.8 -1.3 -0.8 -1.9 -1.9 -2.5 -2.4 -2.7 -2.2 -2.4 -2.0 -1.9 -0.0 -2.2
Mood swings 1.1 1.9 7.4 0.4 1.7 -0.2 0.2 -1.2 1.1 1.0 -1.7 -0.4 -1.7 2.7 1.5 1.7 1.5 0.9 1.2 0.5 1.3 1.1 1.3 1.4 2.4 1.2
Loneliness, isolation 2.1 2.9 12.8 2.6 1.6 -0.6 0.1 -1.3 1.4 0.8 -1.7 -0.1 -1.4 3.6 1.8 2.1 1.6 1.4 1.5 1.3 1.8 1.5 1.8 1.6 2.2 1.7
Long-standing illness, disability or infirmity 0.3 0.5 3.0 1.2 -0.7 -0.9 1.0 0.5 0.4 -0.6 1.2 -1.7 0.9 -0.5 -0.3 0.0 0.2 -0.6 0.0 -1.0 -0.4 0.4 -0.3 0.3 -0.4 0.0
Ever had bowel cancer screening 0.5 0.6 2.4 0.2 0.3 -1.1 -0.1 1.3 -0.3 -0.4 -0.4 -1.5 -0.5 0.7 -0.4 -0.5 -0.3 -1.0 -0.5 -1.3 -0.9 -0.3 -1.2 -0.3 -0.3 -0.7
Diabetes diagnosed by doctor 0.2 0.3 3.9 0.0 -0.5 -2.0 -0.1 0.1 0.2 -0.5 0.6 -0.1 0.7 -0.4 -0.2 0.2 0.3 0.1 0.3 0.1 0.3 0.3 0.2 0.3 -0.3 0.3
Ever had stillbirth, spontaneous miscarriage or termination 1.6 1.7 5.0 2.2 0.1 -0.6 0.8 -1.0 1.3 -0.4 -0.5 -0.1 0.2 1.7 0.8 1.7 1.4 1.8 1.7 1.7 1.8 1.6 1.3 1.4 -0.2 1.8
Friendships satisfaction 1.8 2.2 5.6 2.4 -1.9 -0.5 1.2 -0.9 1.3 -1.7 1.5 -0.6 1.7 1.2 0.3 1.3 1.6 1.8 1.6 1.6 1.6 1.5 1.8 1.6 -0.6 1.9
Qualifications: nursing, teaching 0.9 1.4 5.6 1.0 -2.3 -0.3 1.0 0.0 0.8 -2.0 2.3 -1.0 2.4 -0.6 -0.6 0.2 0.7 0.9 0.9 0.5 0.2 0.9 0.3 0.8 -1.8 0.8
Commuting to job workplace: Walk 1.3 1.5 5.5 -2.3 0.3 -1.3 -0.5 1.1 -1.4 0.8 -0.2 1.3 -0.5 -1.8 -1.4 -1.3 -1.6 -0.9 -1.3 -0.4 -0.9 -1.3 -1.1 -1.6 -0.9 -1.3
Eye problems/disorders: Cataract 0.7 0.8 3.4 0.2 -1.6 -1.8 0.7 0.4 0.3 -1.4 1.6 -0.1 1.6 -0.9 -0.8 -0.4 -0.3 -0.1 -0.0 0.1 0.2 0.3 -0.2 -0.2 -1.8 -0.0
Mouth/teeth dental problems: Mouth ulcers 0.9 1.5 6.3 1.4 1.9 -0.1 -0.4 -2.3 0.5 1.2 -1.4 1.0 -1.5 1.5 2.5 1.3 0.6 0.5 0.3 0.6 0.8 0.6 0.9 0.4 1.8 0.6
Medication for cholesterol 1.2 1.8 3.5 -1.4 -0.1 -1.5 -1.3 1.7 -1.8 0.1 -0.6 0.9 -0.4 -1.0 -1.5 -1.6 -1.9 -1.2 -1.8 -0.7 -1.5 -1.7 -1.1 -1.9 -0.8 -1.5
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.3 0.8 0.2 0.2 -0.1 -0.1 0.7 -0.9 0.4 -0.2 0.2 -0.1 0.0 -0.8 -0.6 -0.8 -0.5 -0.7 -0.3 -0.4 -0.7 -0.5 -0.7 -0.4 -0.5
Back pain experienced in last month 2.3 3.4 9.1 -0.7 3.0 1.8 -2.9 1.0 -1.0 2.1 -3.0 -0.1 -3.0 0.5 -0.2 -0.8 -1.0 -2.2 -1.7 -2.1 -1.7 -1.5 -1.2 -1.0 2.7 -1.8
Mineral and other dietary supplements 0.4 0.6 3.1 -1.0 0.4 -1.7 -0.7 0.1 -0.1 0.7 -1.1 1.6 -0.6 0.3 -0.2 0.2 -0.0 0.4 0.1 1.0 1.0 0.1 0.8 -0.0 0.7 0.3
Breast cancer (self-reported) 1.1 1.3 3.4 1.2 0.7 0.4 1.0 -0.7 1.8 0.1 -0.9 -1.6 -0.4 1.2 1.3 1.3 1.6 0.7 1.6 0.1 0.5 1.7 0.4 1.6 1.1 1.0
Asthma (self-reported) 0.2 0.5 1.1 -1.0 0.6 -0.9 0.1 0.4 -0.6 0.9 -0.0 0.2 -0.4 -0.2 -1.1 -0.8 -0.8 -0.7 -0.7 -0.5 -1.0 -0.6 -0.9 -0.7 -0.0 -0.9
Osteoporosis (self-reported) 0.7 0.9 4.6 0.0 1.9 -0.8 -1.2 -0.8 0.2 1.4 -2.1 0.9 -1.7 0.9 1.0 0.4 0.1 0.1 -0.0 0.4 0.1 0.2 0.2 0.0 1.4 -0.1
Osteoarthritis (self-reported) 2.1 2.7 7.2 2.7 1.1 0.9 0.3 -2.1 1.8 0.2 -1.2 -1.3 -0.8 2.2 2.4 2.1 2.1 1.2 1.7 0.6 1.5 1.7 1.5 2.0 2.0 1.7
Medication: Aspirin 1.4 1.9 9.9 3.1 -0.8 -0.5 1.4 -0.7 1.8 -1.4 0.8 -1.1 1.2 1.1 0.4 1.4 1.5 1.1 1.5 0.9 1.5 1.7 1.2 1.5 -0.2 1.6
Medication: Gliclazide 1.2 1.4 4.5 -0.7 -1.7 -2.1 -0.2 1.9 -0.3 -2.1 1.0 -1.2 1.6 -0.7 -1.9 -1.0 -0.3 -0.4 -0.0 -0.7 -0.7 -0.2 -1.0 -0.1 -2.0 -0.5
Illnesses of father: None of the above (group 1) 1.5 1.8 4.9 -2.2 0.1 1.2 -0.8 0.7 -1.6 1.4 0.2 0.4 -0.5 -2.1 -1.0 -1.7 -1.4 -1.6 -1.7 -1.3 -1.4 -1.8 -1.3 -1.4 -0.3 -1.6
Smoking status: Current 1.4 2.3 7.8 0.6 2.6 0.6 -1.7 -0.6 0.3 2.5 -2.4 1.3 -2.5 2.5 1.5 1.3 0.5 0.7 0.3 0.9 0.5 0.3 1.2 0.4 2.8 0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.1 2.3 8.7 1.7 2.7 1.5 0.1 -2.1 0.5 1.3 -2.4 -0.5 -2.5 1.4 2.9 1.1 0.7 -0.4 -0.1 -0.7 -0.2 0.2 0.4 0.5 2.9 0.2
Whole body water mass 12.0 68.7 234.1 -8.4 -7.8 -9.3 -3.5 14.1 -4.8 -7.4 7.6 -4.7 7.5 -10.3 -15.3 -9.1 -6.1 -7.8 -5.8 -8.0 -7.7 -5.5 -8.1 -4.9 -9.2 -7.4
Leg predicted mass (right) 10.0 53.4 193.2 -7.3 -6.6 -8.8 -3.6 13.0 -4.3 -6.5 6.3 -4.2 6.3 -8.4 -13.9 -7.9 -5.2 -6.9 -5.1 -7.1 -6.6 -5.0 -7.1 -4.1 -7.7 -6.5
Arm fat mass (left) 1.2 4.8 16.9 1.3 -3.2 -3.7 1.0 1.8 2.3 -4.1 2.8 -3.7 3.7 -0.5 -2.1 0.6 1.9 0.3 1.8 -0.7 0.6 2.0 0.5 2.3 -1.3 1.1
Number of self-reported non-cancer illnesses 0.3 0.4 3.3 1.3 0.5 -1.8 -0.9 0.1 0.4 -0.0 0.0 -0.9 -0.1 1.1 0.2 0.5 0.4 -0.3 0.1 -0.3 0.3 0.3 0.3 0.4 0.7 0.2
Average weekly champagne plus white wine intake 0.9 1.3 4.8 -0.8 -0.9 -1.4 0.9 1.1 -1.3 -0.4 0.5 0.1 1.0 -1.4 -2.2 -1.4 -1.2 -0.9 -1.1 -0.6 -1.1 -1.2 -1.0 -1.1 -1.3 -1.0
Miserableness 2.0 3.5 8.1 2.1 1.5 0.9 0.0 -1.9 1.9 0.5 -1.7 0.1 -1.1 2.9 2.1 2.5 2.2 1.9 2.0 1.5 1.6 1.9 2.3 2.2 2.8 2.1
Guilty feelings 0.8 1.3 6.0 0.9 2.4 0.5 0.4 -1.2 -0.4 2.0 -1.9 1.0 -2.1 1.5 0.8 0.7 0.0 0.1 -0.4 0.3 -0.1 -0.3 0.4 -0.2 1.7 0.1
Wears glasses or contact lenses 0.8 0.9 6.1 -0.7 0.0 2.5 2.1 0.3 0.6 -0.1 0.2 -1.8 0.3 -1.0 -0.3 -0.1 0.1 -0.8 0.1 -1.5 -0.8 0.3 -1.0 0.0 -0.2 -0.5
Ever taken oral contraceptive pill 0.7 0.7 2.8 1.7 -0.2 1.3 1.7 -1.2 1.0 -0.3 -0.4 -0.1 0.2 0.6 0.8 0.8 0.7 0.8 0.8 0.8 0.2 1.0 0.8 0.6 0.4 0.8
Hearing aid user 1.8 2.0 4.2 -1.9 0.9 0.7 -0.1 1.5 -1.9 0.7 -0.7 -0.3 -1.1 -1.4 -1.0 -1.7 -1.3 -2.0 -1.7 -2.0 -1.2 -2.0 -1.9 -1.3 -0.2 -1.8
Mother’s age at death 0.9 1.2 2.6 -0.6 -0.8 0.3 1.6 1.1 -0.8 -0.3 0.8 -0.8 0.5 -1.0 -1.3 -1.5 -1.0 -1.3 -1.0 -1.3 -1.3 -0.9 -1.5 -0.9 -1.3 -1.2
Financial situation satisfaction 1.5 1.9 6.7 1.2 2.4 -0.2 -1.2 -0.6 -0.1 2.1 -2.2 0.6 -2.3 2.4 1.3 1.2 0.7 0.5 0.2 0.5 0.9 -0.0 1.1 0.5 2.6 0.8
Tinnitus: Yes, now most or all of the time 0.9 1.1 3.1 -0.8 0.8 -0.0 0.5 1.3 -0.8 0.5 -0.9 -0.8 -1.0 -0.5 -1.5 -1.1 -0.8 -1.6 -1.1 -1.8 -1.2 -1.1 -1.5 -0.8 0.1 -1.2
Commuting to job workplace: Public transport 1.9 2.2 5.2 -2.3 -0.2 -0.9 0.1 1.2 -1.9 0.9 0.5 1.2 -0.3 -1.7 -1.4 -1.9 -2.1 -1.4 -2.0 -0.8 -1.6 -1.9 -1.5 -2.2 -1.2 -1.7
Eye problems/disorders: Glaucoma 0.6 0.7 2.6 1.0 -0.1 -0.0 -0.8 -1.4 0.1 -0.1 -0.3 1.6 0.1 0.3 1.5 0.7 0.1 1.2 0.4 1.5 0.7 0.3 1.2 0.1 0.1 0.8
Medication: Blood pressure 1.2 2.3 4.8 0.9 -0.6 -0.0 1.5 -1.7 2.2 -0.3 1.2 -0.0 1.1 0.8 0.9 1.8 1.8 1.8 2.1 1.6 2.0 2.1 1.9 1.9 0.6 1.9
Pain type(s) experienced in last month: Hip pain 1.9 2.3 6.9 2.6 -1.8 0.0 2.6 0.1 1.6 -2.6 1.3 -2.5 2.0 0.9 -0.6 0.8 1.7 0.9 1.6 0.2 0.2 1.5 0.6 1.8 -0.6 1.3
Supplements: Fish oil (including cod liver oil) 0.7 1.0 2.7 -0.1 -1.1 0.6 1.3 0.2 -0.8 -1.1 1.6 -1.1 1.2 -1.1 -0.3 -1.0 -0.7 -0.6 -0.5 -1.0 -1.3 -0.7 -1.1 -0.7 -1.6 -0.7
High cholesterol (Self-reported) 0.5 0.9 2.4 1.6 -0.1 1.3 1.3 -1.5 0.8 -0.2 0.5 0.5 0.2 0.0 1.3 1.0 0.7 1.1 0.9 1.1 1.2 0.9 1.0 0.7 0.2 1.1
Medication: Bendroflumethiazide 0.4 0.5 2.3 -1.1 -0.1 -1.3 0.5 -1.0 0.6 -0.1 0.6 0.8 0.4 0.1 0.7 0.6 0.4 0.6 0.7 0.8 1.5 0.5 0.9 0.4 0.3 0.6
Medication: Paracetamol 0.6 0.9 3.7 1.9 -0.4 -0.4 1.1 -0.6 1.0 -0.6 0.4 -0.3 0.5 0.9 0.7 1.1 0.9 1.2 1.2 1.0 1.0 1.2 1.1 0.9 -0.1 1.3
Medication: Lisinopril 1.3 1.6 6.8 1.6 0.3 -2.6 1.1 -1.5 1.5 -0.7 -0.6 -0.5 -0.0 1.0 1.2 1.4 1.4 1.1 1.4 1.1 1.6 1.6 1.0 1.4 0.5 1.4
Medication: Atorvastatin 0.1 0.2 1.5 1.2 -0.2 -0.2 0.5 -0.4 0.2 -0.3 0.5 -0.4 0.6 -0.1 0.7 0.3 0.1 0.1 0.1 0.1 0.1 0.2 0.3 0.1 -0.0 0.2
Illnesses of father: High blood pressure 0.6 0.8 6.6 1.1 -0.2 -2.6 0.9 -0.5 0.2 -0.5 -0.3 0.8 0.4 0.7 0.3 0.7 0.3 1.0 0.6 1.2 1.1 0.5 0.9 0.3 -0.4 0.9
Alcohol drinker status: Never 0.9 1.1 4.5 -0.7 2.1 0.3 -0.9 -0.2 -0.8 1.8 -1.7 1.5 -2.1 0.5 0.8 -0.1 -1.0 -0.6 -1.0 -0.0 0.1 -0.8 -0.3 -1.1 1.0 -0.6
Ever smoked 1.7 3.0 9.7 0.7 3.1 0.9 -1.2 -1.3 0.2 2.8 -3.1 1.8 -3.1 2.4 1.7 1.5 0.5 1.0 0.4 1.3 0.8 0.4 1.3 0.2 2.9 0.8
Basal metabolic rate 10.4 57.7 201.6 -7.3 -7.6 -8.8 -3.0 13.1 -3.9 -7.4 7.4 -5.0 7.4 -9.2 -14.2 -8.1 -5.1 -7.0 -4.9 -7.4 -6.8 -4.6 -7.2 -4.0 -8.4 -6.5
Leg fat percentage (left) 4.9 17.8 33.2 5.8 -1.1 0.3 3.8 -5.3 5.2 -2.3 1.0 -2.3 2.0 3.6 5.1 5.1 5.5 4.6 5.3 3.4 4.7 5.3 4.7 5.5 2.0 5.3
Arm fat-free mass (left) 10.2 51.5 172.7 -7.0 -7.6 -8.1 -2.7 12.0 -3.5 -7.2 7.6 -4.8 7.5 -9.2 -13.1 -7.5 -4.6 -6.3 -4.3 -6.9 -6.3 -4.1 -6.7 -3.5 -8.3 -5.9
Number of operations (self-reported) 1.2 1.8 6.9 1.2 0.7 -0.3 0.7 -2.0 1.4 0.3 -0.3 -0.7 -0.6 1.7 2.6 1.4 1.9 0.7 1.2 0.3 1.3 1.2 1.4 1.8 2.2 1.2
Average weekly beer plus cider intake 1.0 1.4 4.2 1.0 1.3 0.8 -0.7 -1.9 0.8 1.1 -1.6 0.7 -1.5 1.4 2.0 1.2 0.6 0.9 0.6 1.1 0.9 0.9 1.3 0.5 1.9 0.9
Irritability 3.2 5.4 11.7 2.2 0.2 3.2 3.2 -2.4 3.4 -0.4 -0.9 -2.1 0.1 2.6 1.3 2.8 3.4 1.7 2.8 0.6 1.8 3.0 1.9 3.3 2.2 2.4
Risk taking 0.9 1.3 3.3 -0.4 -0.9 -1.7 -1.8 1.4 -0.6 -1.6 0.7 -1.5 1.0 -0.8 -1.5 -1.0 -0.6 -0.9 -0.5 -1.2 -1.0 -0.5 -1.4 -0.4 -1.5 -0.9
Ever had prostate specific antigen (PSA) test 1.0 1.2 3.6 -0.1 -1.6 0.5 1.9 0.7 -0.5 -1.4 1.6 -1.2 1.5 -1.0 -1.6 -1.0 -0.1 -1.0 -0.6 -1.3 -1.0 -0.6 -1.0 -0.1 -1.4 -0.6
Fractured/broken bones in last 5 years 0.5 0.6 3.2 -0.2 1.3 0.2 -1.0 -0.0 -0.7 1.2 -1.5 1.8 -1.1 0.7 0.2 0.0 -0.6 0.3 -0.4 0.7 0.1 -0.5 0.2 -0.7 0.6 -0.1
Age started oral contraceptive pill 2.7 3.4 8.9 -2.1 0.6 2.7 -0.2 1.7 -1.2 1.1 0.4 -1.5 -0.7 -1.7 -0.9 -2.1 -1.7 -2.6 -1.8 -3.0 -2.7 -1.6 -2.9 -1.7 -0.6 -2.5
Diastolic blood pressure, automated reading 0.7 2.1 6.0 1.6 0.0 -2.5 0.4 -0.9 1.9 -1.5 -0.3 -1.5 0.4 1.9 1.3 1.7 2.0 1.2 1.8 0.5 1.2 1.8 1.2 2.0 1.1 1.5
Ever depressed for a whole week 0.2 0.3 1.1 0.8 0.5 0.7 -0.6 0.0 0.5 -0.1 -0.7 -0.9 -0.6 0.8 -0.0 0.1 0.6 -0.2 0.2 -0.4 -0.2 0.3 0.0 0.7 1.0 0.0
Unable to work because of sickness or disability 3.3 4.3 11.6 2.2 2.0 -0.4 -1.0 -1.5 2.1 1.0 -2.6 -0.1 -1.9 3.0 2.7 2.6 2.3 1.6 1.8 1.4 2.1 2.0 2.3 2.3 3.4 2.0
Commuting to job workplace: Cycle 0.8 1.0 3.0 -1.2 0.6 -1.3 -1.7 1.6 -0.9 0.5 -1.2 1.3 -0.8 0.1 -1.7 -0.6 -1.1 -0.5 -0.9 0.0 -0.2 -0.8 -0.4 -1.1 -0.2 -0.7
Myopia 0.8 1.1 4.3 -2.1 0.6 -0.8 0.6 0.7 -1.6 0.9 -0.2 1.0 -0.2 -1.0 -1.8 -1.0 -1.3 -0.8 -1.2 -0.6 -0.6 -1.4 -1.0 -1.3 -0.6 -1.1
Vascular/heart problems diagnosed by doctor 2.2 6.0 10.9 -2.6 0.9 2.7 -1.2 2.5 -3.3 1.7 -0.9 0.6 -1.5 -2.0 -2.3 -2.9 -3.0 -2.6 -3.0 -2.3 -3.3 -3.3 -3.1 -3.1 -1.1 -3.1
Cholesterol lowering medication 0.4 0.6 2.7 1.4 -0.6 1.6 1.3 -0.8 0.5 -0.5 1.4 -0.2 0.9 -0.5 0.7 0.5 0.2 0.3 0.4 0.3 0.8 0.5 0.5 0.3 -0.5 0.6
Medication: Omeprazole (e.g. Zanprol) 0.1 0.2 1.3 1.1 -0.4 0.1 1.2 -0.5 0.4 0.2 0.4 -0.3 0.2 -0.1 0.1 -0.1 0.2 0.0 0.2 0.1 0.1 0.3 0.1 0.2 -0.0 0.3
Pain experienced in last month 0.9 1.4 6.0 -1.0 -2.1 -0.1 0.4 0.9 -0.7 -0.8 2.3 0.8 1.8 -1.7 -1.8 -1.1 -1.1 -0.1 -0.6 0.4 -0.2 -0.6 -0.4 -0.9 -2.5 -0.4
Supplements: Calcium 0.3 0.3 1.9 0.8 0.7 -1.4 -0.5 0.2 0.4 -0.2 -0.5 -0.6 -0.6 1.0 0.5 0.4 0.4 -0.0 0.3 -0.2 0.2 0.5 0.0 0.5 0.6 0.2
Basal cell carcinoma (self-reported) 2.1 2.5 14.6 1.2 -0.4 1.6 3.8 1.2 0.8 -1.2 0.1 -3.6 0.5 0.9 -1.7 -0.6 1.0 -1.6 -0.1 -2.7 -1.9 0.2 -1.4 1.0 0.7 -0.7
Heart attack/myocardial infarction (self-reported) 1.8 2.3 8.2 2.3 -1.1 0.4 2.8 -0.8 2.2 -1.1 1.2 -2.9 1.2 0.5 0.8 1.3 2.1 0.5 1.5 -0.4 0.6 1.8 1.0 2.1 0.8 1.4
Deep venous thrombosis (DVT) (self-reported) 15.3 19.7 34.3 -5.2 -1.8 -1.0 -3.1 4.8 -5.9 0.1 2.7 0.1 1.1 -5.9 -4.1 -5.8 -5.4 -5.0 -5.5 -4.2 -4.8 -5.8 -5.0 -5.2 -4.4 -5.3
Heart disease (siblings) 1.1 1.3 7.8 1.7 0.6 -1.5 0.5 0.1 1.3 -1.4 -1.1 -2.8 -0.3 0.9 1.1 0.7 1.2 -0.4 0.6 -1.4 -1.0 0.8 -0.2 1.2 1.5 0.1
Alcohol drinker status: Previous 0.8 1.0 1.9 -1.2 -0.0 0.5 -0.0 0.9 -1.4 0.9 0.8 0.4 -0.0 -1.3 -1.3 -1.1 -1.4 -0.9 -1.3 -0.6 -1.0 -1.3 -0.9 -1.3 -0.8 -1.1
Pack years of smoking 1.7 2.5 8.3 -1.2 0.1 -1.3 -1.2 2.4 -1.0 0.1 0.3 -1.7 -0.3 -1.1 -1.6 -1.7 -1.2 -2.7 -1.9 -2.9 -1.7 -1.4 -2.1 -1.2 -0.3 -2.1
Impedance of whole body 1.3 6.8 34.0 2.0 3.7 5.8 1.1 -3.1 0.9 3.7 -3.3 0.6 -3.7 3.5 3.9 1.6 1.1 0.2 0.3 0.0 0.2 0.6 1.1 0.7 4.5 0.5
Leg fat mass (left) 1.7 6.6 19.2 2.5 -3.4 -2.9 2.2 0.1 3.2 -4.4 3.0 -3.6 4.0 0.1 -0.6 1.6 3.0 1.5 2.9 0.4 1.6 3.0 1.5 3.3 -1.1 2.3
Arm predicted mass (left) 10.4 52.7 174.2 -7.1 -7.8 -8.2 -2.8 12.2 -3.5 -7.4 7.8 -4.8 7.6 -9.3 -13.2 -7.6 -4.7 -6.3 -4.3 -6.8 -6.3 -4.2 -6.7 -3.6 -8.5 -5.9