Best TWAS P=8.14e-23 · Best GWAS P=1.84e-22 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | FLRT2 | 0.11 | 0.01 | enet | 45 | 0.06 | 2.6e-05 | 3.0 | 6.4 | 1.3e-10 | -0.58 | 0.02 | 0.93 | FALSE |
| 2 | GTEx | Breast Mammary Tissue (Female) | FLRT2 | 0.06 | 0.02 | lasso | 3 | 0.03 | 4.9e-02 | -9.7 | 9.8 | 8.1e-23 | -0.99 | 0.01 | 0.87 | TRUE |
| 3 | GTEx | Heart Atrial Appendage | FLRT2 | 0.21 | 0.06 | lasso | 3 | 0.05 | 2.3e-03 | -9.7 | 9.7 | 2.0e-22 | -0.99 | 0.01 | 0.97 | FALSE |
| 4 | GTEx | Nerve Tibial | FLRT2 | 0.21 | 0.14 | enet | 12 | 0.15 | 8.4e-11 | -9.7 | 8.8 | 9.4e-19 | -0.92 | 0.01 | 0.99 | FALSE |
| 5 | GTEx | Skin Not Sun Exposed Suprapubic | FLRT2 | 0.21 | 0.05 | lasso | 5 | 0.03 | 1.1e-02 | 2.3 | 5.3 | 1.2e-07 | -0.50 | 0.03 | 0.83 | FALSE |
| 6 | GTEx | Skin Sun Exposed Lower leg | FLRT2 | 0.08 | 0.02 | enet | 22 | 0.00 | 2.0e-01 | -6.4 | 5.7 | 9.2e-09 | -0.40 | 0.14 | 0.26 | FALSE |