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chr15:72,287,856-74,291,976
Best TWAS P=2.41e-17 · Best GWAS P=3.52e-19 conditioned to 1.08e-05
72.5M
73M
73.5M
74M
0
5
10
15
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Thyroid Carcinoma
HCN4
0.03
0.00
blup
52
0.02
2.0e-03
1.5
8.5
2.4e-17
-0.52
0.01
0.45
TRUE
5
The Cancer Genome Atlas
Thyroid Carcinoma
NEO1
0.03
0.02
lasso
3
0.02
6.2e-03
7.6
-7.0
3.0e-12
0.29
0.05
0.52
TRUE
1
GTEx
Pituitary
BBS4
0.27
0.02
enet
21
0.05
2.1e-02
-4.4
-5.6
2.0e-08
0.07
0.08
0.16
TRUE
3
NTR
Blood
NEO1
0.04
0.01
lasso
4
0.02
4.1e-06
5.7
-6.4
1.7e-10
0.33
0.92
0.02
FALSE
2
GTEx
Spleen
NEO1
0.39
0.00
lasso
9
0.01
2.0e-01
7.8
-6.0
1.8e-09
0.22
0.06
0.06
FALSE