336 significantly associated models · 108 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 207814451 | 208331649 | 1 | 1 | 1.5e-07 | 1.8e-19 | 1.8e-13 | 33 | CD34 |
2 | 2 | 17446185 | 18230779 | 2 | 2 | 3.5e-08 | 1.9e-09 | 1.0e-01 | 93 | RAD51AP2 SMC6 |
3 | 2 | 27467598 | 27949052 | 1 | 1 | 1.8e-10 | 1.1e-09 | 1.0e+00 | 100 | FNDC4 |
4 | 2 | 178362572 | 179939959 | 2 | 2 | 6.3e-10 | 6.3e-41 | 2.1e-29 | 29 | OSBPL6 TTN |
5 | 3 | 48012797 | 51043528 | 22 | 1 | 1.0e-09 | 2.0e-08 | 6.1e-03 | 76 | TRAIP |
6 | 3 | 52565100 | 53985919 | 1 | 1 | 1.4e-07 | 9.2e-08 | 6.8e-03 | 74 | TKT |
7 | 3 | 140350567 | 141867638 | 1 | 1 | 6.7e-08 | 1.8e-08 | 1.0e+00 | 100 | ZBTB38 |
8 | 5 | 122434666 | 123002130 | 1 | 1 | 1.1e-07 | 4.3e-07 | 7.2e-02 | 87 | CEP120 |
9 | 5 | 136386984 | 138474788 | 5 | 2 | 7.8e-11 | 7.8e-11 | 1.0e+00 | 100 | REEP2 RP11-381K20.5 |
10 | 6 | 118089396 | 119949791 | 3 | 2 | 1.8e-19 | 2.9e-25 | 7.5e-04 | 90 | C6orf204 MCM9 |
11 | 6 | 120704438 | 122457698 | 3 | 4 | 2.2e-17 | 5.4e-38 | 1.7e-12 | 70 | C6orf170 GJA1 TBC1D32 |
12 | 6 | 133961374 | 134468561 | 1 | 1 | 3.3e-08 | 1.9e-09 | 7.9e-03 | 80 | TCF21 |
13 | 7 | 99060603 | 101185166 | 19 | 1 | 1.2e-28 | 8.2e-26 | 1.2e-01 | 98 | GIGYF1 |
14 | 9 | 35213538 | 36597142 | 2 | 1 | 1.5e-09 | 6.7e-09 | 1.0e+00 | 100 | LOC158376 |
15 | 11 | 13288698 | 14975818 | 1 | 1 | 1.3e-07 | 6.7e-08 | 1.3e-01 | 92 | SPON1 |
16 | 11 | 60839578 | 62346131 | 6 | 1 | 1.0e-13 | 1.1e-13 | 3.4e-02 | 92 | FADS1 |
17 | 11 | 64700767 | 65226187 | 1 | 1 | 1.3e-07 | 4.3e-06 | 2.1e-01 | 93 | CAPN1 |
18 | 12 | 33480976 | 34826574 | 1 | 2 | 4.3e-13 | 4.5e-24 | 7.1e-11 | 58 | ALG10 |
19 | 12 | 38353816 | 39998144 | 1 | 1 | 9.1e-08 | 1.0e-07 | 1.9e-01 | 94 | CPNE8 |
20 | 13 | 41092698 | 42640341 | 2 | 1 | 3.2e-09 | 9.0e-07 | 7.0e-01 | 99 | NAA16 |
21 | 14 | 20843889 | 22255090 | 1 | 1 | 1.2e-08 | 1.9e-15 | 1.2e-09 | 41 | ARHGEF40 |
22 | 14 | 22670975 | 24501100 | 8 | 6 | 2.3e-24 | 1.5e-61 | 2.0e-21 | 67 | CMTM5 HOMEZ NGDN RBM23 SLC22A17 THTPA |
23 | 14 | 85303548 | 86791228 | 1 | 1 | 8.1e-23 | 1.8e-22 | 1.0e+00 | 100 | FLRT2 |
24 | 15 | 72287856 | 74291976 | 3 | 3 | 2.4e-17 | 3.5e-19 | 1.1e-05 | 76 | BBS4 HCN4 NEO1 |
25 | 17 | 14714000 | 16109675 | 1 | 1 | 1.2e-07 | 8.1e-07 | 3.1e-06 | 11 | AC005517.3 |
26 | 19 | 38444944 | 39914308 | 1 | 1 | 4.5e-09 | 1.9e-09 | 5.6e-02 | 90 | ACTN4 |
27 | 20 | 35835657 | 37586842 | 2 | 3 | 1.2e-22 | 3.7e-51 | 5.8e-16 | 71 | KIAA1755 VSTM2L |
28 | 22 | 38192452 | 39859169 | 9 | 1 | 2.6e-08 | 4.4e-08 | 1.0e+00 | 100 | RP3-508I15.9 |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Heart Atrial Appendage | 8 | 0.507 | 2.1 |
GTEx | Brain Putamen basal ganglia | 5 | 0.801 | 2.0 |
GTEx | Ovary | 3 | 0.330 | 2.0 |
GTEx | Heart Left Ventricle | 6 | 0.392 | 1.9 |
GTEx | Skin Not Sun Exposed Suprapubic | 9 | 0.366 | 1.9 |
GTEx | Artery Aorta | 7 | 0.235 | 1.8 |
GTEx | Artery Coronary | 3 | 0.254 | 1.8 |
GTEx | Artery Tibial | 11 | 0.292 | 1.8 |
GTEx | Colon Transverse | 6 | 0.291 | 1.8 |
GTEx | Esophagus Gastroesophageal Junction | 5 | 0.346 | 1.8 |
GTEx | Esophagus Mucosa | 13 | 0.392 | 1.8 |
GTEx | Liver | 2 | 0.279 | 1.8 |
GTEx | Muscle Skeletal | 9 | 0.311 | 1.8 |
GTEx | Nerve Tibial | 18 | 0.417 | 1.8 |
GTEx | Pituitary | 4 | 0.359 | 1.8 |
GTEx | Skin Sun Exposed Lower leg | 15 | 0.412 | 1.8 |
GTEx | Vagina | 2 | 0.315 | 1.8 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 2 | 0.182 | 1.8 |
GTEx | Adipose Subcutaneous | 8 | 0.229 | 1.7 |
GTEx | Adipose Visceral Omentum | 5 | 0.246 | 1.7 |
GTEx | Adrenal Gland | 1 | 0.069 | 1.7 |
GTEx | Brain Cerebellar Hemisphere | 2 | 0.134 | 1.7 |
GTEx | Brain Cerebellum | 4 | 0.202 | 1.7 |
GTEx | Breast Mammary Tissue (Female) | 4 | 0.243 | 1.7 |
GTEx | Cells Transformed fibroblasts | 9 | 0.214 | 1.7 |
GTEx | Colon Sigmoid | 2 | 0.137 | 1.7 |
GTEx | Esophagus Muscularis | 5 | 0.155 | 1.7 |
GTEx | Lung | 5 | 0.174 | 1.7 |
GTEx | Pancreas | 3 | 0.184 | 1.7 |
GTEx | Prostate | 2 | 0.240 | 1.7 |
GTEx | Spleen | 3 | 0.213 | 1.7 |
GTEx | Stomach | 5 | 0.344 | 1.7 |
GTEx | Testis | 11 | 0.349 | 1.7 |
GTEx | Thyroid | 10 | 0.250 | 1.7 |
GTEx | Uterus | 3 | 0.529 | 1.7 |
NTR | Blood | 3 | 0.125 | 1.7 |
ROSMAP | Brain Pre-frontal Cortex | 13 | 0.296 | 1.7 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 8 | 0.182 | 1.7 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 3 | 0.110 | 1.7 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 7 | 0.238 | 1.7 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 2 | 0.126 | 1.7 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 2 | 0.120 | 1.7 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 0 | 0.000 | 1.7 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 0 | 0.000 | 1.7 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 4 | 0.313 | 1.7 |
The Cancer Genome Atlas | Thyroid Carcinoma | 15 | 0.291 | 1.7 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 0 | 0.000 | 1.7 |
GTEx | Brain Caudate basal ganglia | 1 | 0.109 | 1.6 |
GTEx | Brain Cortex | 0 | 0.000 | 1.6 |
GTEx | Brain Frontal Cortex BA9 | 0 | 0.000 | 1.6 |
GTEx | Brain Hypothalamus | 1 | 0.169 | 1.6 |
GTEx | Brain Nucleus accumbens basal ganglia | 3 | 0.347 | 1.6 |
GTEx | Breast Mammary Tissue | 5 | 0.253 | 1.6 |
GTEx | Cells EBV-transformed lymphocytes | 0 | 0.000 | 1.6 |
GTEx | Small Intestine Terminal Ileum | 1 | 0.217 | 1.6 |
GTEx | Whole Blood | 6 | 0.301 | 1.6 |
METSIM | Adipose | 10 | 0.217 | 1.6 |
YFS | Blood | 4 | 0.087 | 1.6 |
CommonMind | Brain Pre-frontal Cortex | 10 | 0.186 | 1.6 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 1 | 0.060 | 1.6 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 5 | 0.242 | 1.6 |
The Cancer Genome Atlas | Esophageal Carcinoma | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 1 | 0.024 | 1.6 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 6 | 0.293 | 1.6 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 3 | 0.070 | 1.6 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 2 | 0.181 | 1.6 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 3 | 0.120 | 1.6 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 1 | 0.075 | 1.6 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 4 | 0.087 | 1.6 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 0 | 0.000 | 1.6 |
GTEx | Brain Hippocampus | 0 | 0.000 | 1.5 |
GTEx | Breast Mammary Tissue (Male) | 1 | 0.084 | 1.5 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 1 | 0.098 | 1.5 |