Best TWAS P=1.22e-07 · Best GWAS P=8.14e-07 conditioned to 3.1e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | AC005517.3 | 0.11 | 0.07 | lasso | 6 | 0.06 | 6.2e-06 | -4.8 | 5.3 | 1.2e-07 | 0.05 | 0.01 | 0.98 | TRUE |
| 2 | GTEx | Breast Mammary Tissue | AC005517.3 | 0.20 | 0.12 | lasso | 4 | 0.06 | 3.3e-04 | -4.8 | 5.3 | 1.4e-07 | 0.04 | 0.01 | 0.98 | FALSE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | AC005517.3 | 0.16 | 0.12 | lasso | 5 | 0.13 | 9.4e-08 | -4.8 | 5.2 | 2.3e-07 | 0.04 | 0.01 | 0.99 | FALSE |
| 4 | GTEx | Skin Sun Exposed Lower leg | AC005517.3 | 0.17 | 0.19 | lasso | 7 | 0.21 | 6.9e-17 | -4.8 | 5.3 | 1.4e-07 | 0.04 | 0.01 | 0.98 | FALSE |