Best TWAS P=4.48e-09 · Best GWAS P=1.94e-09 conditioned to 0.0555
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | ACTN4 | 0.17 | 0.11 | lasso | 5 | 0.13 | 6.0e-10 | -5.7 | -5.9 | 4.5e-09 | 0.85 | 0.02 | 0.98 | TRUE |
| 2 | GTEx | Muscle Skeletal | ACTN4 | 0.08 | 0.06 | lasso | 3 | 0.05 | 5.9e-06 | -5.7 | -5.8 | 7.1e-09 | 0.91 | 0.02 | 0.98 | FALSE |