TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Hand grip strength (left)
:
→
chr1:9,576,675-11,137,778
Best TWAS P=7.11e-09 · Best GWAS P=1.74e-08 conditioned to 1
9.6M
9.8M
10M
10.2M
10.4M
10.6M
10.8M
11M
11.2M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
NTR
Blood
KIF1B
0.11
0.08
enet
11
0.09
3.7e-28
-5.2
-5.8
7.1e-09
0.95
0.00
1.00
TRUE
4
The Cancer Genome Atlas
Stomach Adenocarcinoma
CORT
0.06
0.03
enet
5
0.04
7.1e-04
4.1
-5.2
1.7e-07
0.24
0.01
0.58
TRUE
3
YFS
Blood
KIF1B
0.30
0.26
enet
49
0.29
7.8e-97
-5.2
-5.7
1.1e-08
0.91
0.01
0.99
FALSE
1
GTEx
Brain Caudate basal ganglia
KIF1B
0.25
0.00
lasso
5
0.02
1.1e-01
4.0
5.4
8.3e-08
-0.57
0.03
0.49
FALSE