Best TWAS P=7.11e-09 · Best GWAS P=1.74e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Caudate basal ganglia | KIF1B | 0.25 | 0.00 | lasso | 5 | 0.02 | 1.1e-01 | 4.0 | 5.4 | 8.3e-08 | -0.57 | 0.03 | 0.49 | FALSE |
| 2 | NTR | Blood | KIF1B | 0.11 | 0.08 | enet | 11 | 0.09 | 3.7e-28 | -5.2 | -5.8 | 7.1e-09 | 0.95 | 0.00 | 1.00 | TRUE |
| 3 | YFS | Blood | KIF1B | 0.30 | 0.26 | enet | 49 | 0.29 | 7.8e-97 | -5.2 | -5.7 | 1.1e-08 | 0.91 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Stomach Adenocarcinoma | CORT | 0.06 | 0.03 | enet | 5 | 0.04 | 7.1e-04 | 4.1 | -5.2 | 1.7e-07 | 0.24 | 0.01 | 0.58 | TRUE |