Best TWAS P=2.04e-07 · Best GWAS P=1.59e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cortex | LUZP1 | 0.23 | 0.14 | lasso | 5 | 0.10 | 7.8e-04 | -5.2 | 5.2 | 2.2e-07 | -0.98 | 0.02 | 0.79 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | LUZP1 | 0.09 | 0.09 | lasso | 4 | 0.08 | 2.8e-06 | -5.2 | 5.2 | 2.0e-07 | -0.98 | 0.01 | 0.99 | TRUE |
| 3 | GTEx | Skin Sun Exposed Lower leg | LUZP1 | 0.07 | 0.03 | enet | 13 | 0.07 | 1.2e-06 | -3.3 | 5.2 | 2.7e-07 | -0.62 | 0.01 | 0.95 | FALSE |