Best TWAS P=4.44e-16 · Best GWAS P=5.07e-14 conditioned to 0.0368
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TGFA | 0.11 | 0.10 | enet | 7 | 0.12 | 5.5e-14 | -7.5 | 7.8 | 6.3e-15 | -0.94 | 0.00 | 1.00 | TRUE |
| 2 | GTEx | Nerve Tibial | TGFA | 0.09 | 0.05 | lasso | 3 | 0.03 | 6.2e-03 | 5.9 | 6.2 | 4.1e-10 | -0.45 | 0.39 | 0.19 | FALSE |
| 3 | GTEx | Testis | TGFA | 0.62 | 0.62 | enet | 67 | 0.64 | 3.2e-36 | 5.9 | -5.9 | 3.4e-09 | 0.64 | 0.99 | 0.01 | FALSE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | TGFA | 0.09 | 0.03 | bslmm | 191 | 0.04 | 7.4e-06 | 6.3 | 8.1 | 4.4e-16 | -0.48 | 0.00 | 1.00 | TRUE |