[Hub]/) : Traits : Hand grip strength (left) : ← →

chr2:134,513,621-137,435,625

Best TWAS P=1.22e-13 · Best GWAS P=3.35e-12 conditioned to 0.195

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	CommonMind	Brain Pre-frontal Cortex	LOC100129961	0.17	0.14	enet	9	0.14	2.6e-17	-6.9	-7.4	1.2e-13	-0.85	0.02	0.98	TRUE
20	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ACMSD	0.04	0.01	blup	46	0.02	2.2e-03	6.7	7.2	6.6e-13	0.89	0.02	0.87	FALSE
15	NTR	Blood	CCNT2	0.01	0.00	blup	370	0.00	6.7e-02	6.9	6.8	1.1e-11	0.70	0.04	0.86	FALSE
10	GTEx	Testis	CCNT2	0.31	0.26	lasso	6	0.26	9.3e-12	7.0	6.7	2.8e-11	0.99	0.01	0.99	FALSE
12	GTEx	Thyroid	CCNT2	0.09	0.10	lasso	2	0.09	1.8e-07	6.7	6.6	3.3e-11	0.97	0.03	0.97	FALSE
11	GTEx	Testis	AC016725.4	0.18	0.09	lasso	6	0.09	6.3e-05	-6.9	6.6	4.1e-11	0.63	0.03	0.97	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	CCNT2	0.06	0.03	enet	27	0.05	1.6e-06	5.9	6.5	1.0e-10	0.84	0.23	0.76	FALSE
7	GTEx	Nerve Tibial	AC016725.4	0.15	0.06	lasso	6	0.02	8.1e-03	6.7	-6.3	3.4e-10	-0.92	0.08	0.91	FALSE
8	GTEx	Prostate	AC016725.4	0.27	0.03	enet	23	0.13	4.6e-04	-6.3	-6.2	5.0e-10	-0.63	0.04	0.89	FALSE
4	GTEx	Artery Aorta	CCNT2	0.12	0.12	lasso	3	0.11	1.9e-06	5.9	5.9	3.4e-09	0.88	0.12	0.85	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CCNT2	0.12	0.11	lasso	2	0.10	9.8e-13	5.9	5.9	4.2e-09	0.88	0.20	0.80	FALSE
5	GTEx	Brain Cerebellar Hemisphere	AC016725.4	0.27	0.18	lasso	4	0.24	8.3e-07	6.7	-5.7	1.1e-08	-0.91	0.05	0.90	FALSE
14	GTEx	Whole Blood	TMEM163	0.11	0.06	lasso	7	0.06	5.0e-06	4.4	-5.7	1.3e-08	-0.58	0.59	0.36	FALSE
9	GTEx	Skin Not Sun Exposed Suprapubic	DARS	0.15	0.11	enet	4	0.10	3.0e-06	5.0	5.4	7.3e-08	0.36	0.03	0.96	FALSE
18	YFS	Blood	CCNT2	0.01	0.01	blup	363	0.01	6.3e-05	5.9	5.4	7.5e-08	0.67	0.10	0.86	FALSE
3	CommonMind	Brain Pre-frontal Cortex	TMEM163	0.05	0.02	lasso	7	0.01	5.9e-03	3.7	-5.3	1.1e-07	-0.77	0.04	0.87	FALSE
21	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	DARS	0.02	0.02	lasso	2	0.02	3.9e-03	5.3	5.3	1.1e-07	0.38	0.01	0.92	FALSE
22	The Cancer Genome Atlas	Soft Tissue Sarcoma	DARS	0.04	0.04	blup	40	0.04	1.6e-03	5.3	5.3	1.3e-07	0.38	0.02	0.92	FALSE
6	GTEx	Esophagus Muscularis	TMEM163	0.09	0.05	lasso	6	0.05	4.8e-04	4.4	-5.2	1.6e-07	-0.51	0.13	0.84	FALSE
13	GTEx	Thyroid	DARS	0.20	0.13	lasso	3	0.15	1.3e-11	4.9	5.2	1.7e-07	0.36	0.09	0.91	FALSE
16	NTR	Blood	MCM6	0.02	0.02	lasso	2	0.03	1.2e-08	4.0	5.2	1.9e-07	0.41	0.05	0.95	FALSE
19	The Cancer Genome Atlas	Breast Invasive Carcinoma	LCT	0.02	0.02	enet	3	0.03	7.6e-07	4.4	-5.2	1.9e-07	-0.41	0.03	0.96	FALSE