[Hub]/) : Traits : Hand grip strength (left) :

chr2:134,513,621-137,435,625

Best TWAS P=1.22e-13 · Best GWAS P=3.35e-12 conditioned to 0.195

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CCNT2 0.12 0.11 lasso 2 0.10 9.8e-13 5.9 5.9 4.2e-09 0.88 0.20 0.80 FALSE
2 CommonMind Brain Pre-frontal Cortex LOC100129961 0.17 0.14 enet 9 0.14 2.6e-17 -6.9 -7.4 1.2e-13 -0.85 0.02 0.98 TRUE
3 CommonMind Brain Pre-frontal Cortex TMEM163 0.05 0.02 lasso 7 0.01 5.9e-03 3.7 -5.3 1.1e-07 -0.77 0.04 0.87 FALSE
4 GTEx Artery Aorta CCNT2 0.12 0.12 lasso 3 0.11 1.9e-06 5.9 5.9 3.4e-09 0.88 0.12 0.85 FALSE
5 GTEx Brain Cerebellar Hemisphere AC016725.4 0.27 0.18 lasso 4 0.24 8.3e-07 6.7 -5.7 1.1e-08 -0.91 0.05 0.90 FALSE
6 GTEx Esophagus Muscularis TMEM163 0.09 0.05 lasso 6 0.05 4.8e-04 4.4 -5.2 1.6e-07 -0.51 0.13 0.84 FALSE
7 GTEx Nerve Tibial AC016725.4 0.15 0.06 lasso 6 0.02 8.1e-03 6.7 -6.3 3.4e-10 -0.92 0.08 0.91 FALSE
8 GTEx Prostate AC016725.4 0.27 0.03 enet 23 0.13 4.6e-04 -6.3 -6.2 5.0e-10 -0.63 0.04 0.89 FALSE
9 GTEx Skin Not Sun Exposed Suprapubic DARS 0.15 0.11 enet 4 0.10 3.0e-06 5.0 5.4 7.3e-08 0.36 0.03 0.96 FALSE
10 GTEx Testis CCNT2 0.31 0.26 lasso 6 0.26 9.3e-12 7.0 6.7 2.8e-11 0.99 0.01 0.99 FALSE
11 GTEx Testis AC016725.4 0.18 0.09 lasso 6 0.09 6.3e-05 -6.9 6.6 4.1e-11 0.63 0.03 0.97 FALSE
12 GTEx Thyroid CCNT2 0.09 0.10 lasso 2 0.09 1.8e-07 6.7 6.6 3.3e-11 0.97 0.03 0.97 FALSE
13 GTEx Thyroid DARS 0.20 0.13 lasso 3 0.15 1.3e-11 4.9 5.2 1.7e-07 0.36 0.09 0.91 FALSE
14 GTEx Whole Blood TMEM163 0.11 0.06 lasso 7 0.06 5.0e-06 4.4 -5.7 1.3e-08 -0.58 0.59 0.36 FALSE
15 NTR Blood CCNT2 0.01 0.00 blup 370 0.00 6.7e-02 6.9 6.8 1.1e-11 0.70 0.04 0.86 FALSE
16 NTR Blood MCM6 0.02 0.02 lasso 2 0.03 1.2e-08 4.0 5.2 1.9e-07 0.41 0.05 0.95 FALSE
17 ROSMAP Brain Pre-frontal Cortex CCNT2 0.06 0.03 enet 27 0.05 1.6e-06 5.9 6.5 1.0e-10 0.84 0.23 0.76 FALSE
18 YFS Blood CCNT2 0.01 0.01 blup 363 0.01 6.3e-05 5.9 5.4 7.5e-08 0.67 0.10 0.86 FALSE
19 The Cancer Genome Atlas Breast Invasive Carcinoma LCT 0.02 0.02 enet 3 0.03 7.6e-07 4.4 -5.2 1.9e-07 -0.41 0.03 0.96 FALSE
20 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ACMSD 0.04 0.01 blup 46 0.02 2.2e-03 6.7 7.2 6.6e-13 0.89 0.02 0.87 FALSE
21 The Cancer Genome Atlas Lung Squamous Cell Carcinoma DARS 0.02 0.02 lasso 2 0.02 3.9e-03 5.3 5.3 1.1e-07 0.38 0.01 0.92 FALSE
22 The Cancer Genome Atlas Soft Tissue Sarcoma DARS 0.04 0.04 blup 40 0.04 1.6e-03 5.3 5.3 1.3e-07 0.38 0.02 0.92 FALSE