[Hub]/) : Traits : Hand grip strength (left) : ← →

chr9:126,844,856-128,643,415

Best TWAS P=2.05e-10 · Best GWAS P=9.54e-10 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	GTEx	Nerve Tibial	GOLGA1	0.07	0.04	lasso	2	0.03	5.6e-03	6.1	6.4	2.0e-10	0.95	0.01	0.97	TRUE
11	GTEx	Muscle Skeletal	GOLGA1	0.07	0.02	lasso	4	0.02	2.2e-03	5.7	6.1	1.3e-09	0.88	0.02	0.97	FALSE
14	GTEx	Thyroid	GOLGA1	0.07	0.01	lasso	5	0.01	1.0e-01	5.3	5.8	8.7e-09	0.86	0.06	0.82	FALSE
3	GTEx	Artery Tibial	GOLGA1	0.09	0.09	lasso	4	0.09	7.0e-08	5.4	5.7	9.7e-09	0.85	0.05	0.95	FALSE
2	GTEx	Adipose Subcutaneous	SCAI	0.07	0.05	lasso	4	0.02	7.4e-03	5.6	-5.7	1.2e-08	-0.89	0.03	0.97	FALSE
4	GTEx	Brain Caudate basal ganglia	OLFML2A	0.12	0.10	lasso	4	0.03	3.7e-02	5.7	5.6	1.9e-08	0.88	0.03	0.87	FALSE
6	GTEx	Brain Cerebellum	ARPC5L	0.31	0.37	enet	7	0.27	1.5e-08	5.5	5.6	1.9e-08	0.92	0.04	0.96	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	GOLGA1	0.08	0.07	bslmm	281	0.07	2.3e-09	5.5	5.6	2.4e-08	0.84	0.06	0.94	FALSE
10	GTEx	Lung	GOLGA1	0.10	0.07	lasso	5	0.08	5.7e-07	-4.7	5.5	2.9e-08	0.72	0.11	0.89	FALSE
20	The Cancer Genome Atlas	Brain Lower Grade Glioma	SCAI	0.02	0.02	blup	94	0.01	2.1e-02	5.5	-5.5	2.9e-08	-0.88	0.02	0.90	FALSE
8	GTEx	Esophagus Muscularis	PPP6C	0.05	0.03	lasso	3	0.01	1.2e-01	5.7	-5.5	3.6e-08	-0.83	0.05	0.67	FALSE
9	GTEx	Esophagus Muscularis	GOLGA1	0.12	0.05	lasso	9	0.06	2.4e-04	5.5	5.5	3.6e-08	0.88	0.04	0.95	FALSE
5	GTEx	Brain Cerebellar Hemisphere	ARPC5L	0.21	0.34	lasso	2	0.32	6.1e-09	5.5	-5.5	4.0e-08	-0.91	0.05	0.95	FALSE
7	GTEx	Colon Transverse	GOLGA1	0.10	0.13	lasso	1	0.09	5.9e-05	5.5	5.5	4.5e-08	0.91	0.05	0.95	FALSE
19	The Cancer Genome Atlas	Brain Lower Grade Glioma	OLFML2A	0.06	0.03	blup	33	0.03	1.6e-04	5.7	-5.5	5.2e-08	-0.74	0.00	0.99	FALSE
21	The Cancer Genome Atlas	Thyroid Carcinoma	WDR38	0.02	0.02	blup	33	0.02	5.0e-03	4.7	-5.4	8.0e-08	-0.88	0.01	0.81	FALSE
1	GTEx	Adipose Subcutaneous	GOLGA1	0.04	0.05	lasso	1	0.05	8.6e-05	5.4	5.4	8.2e-08	0.92	0.05	0.93	FALSE
18	The Cancer Genome Atlas	Brain Lower Grade Glioma	GOLGA1	0.04	0.04	enet	11	0.02	7.2e-04	5.3	5.3	1.4e-07	0.78	0.03	0.82	FALSE
16	METSIM	Adipose	ARPC5L	0.02	0.01	blup	270	0.02	1.5e-03	4.3	5.2	2.2e-07	0.83	0.08	0.84	FALSE
13	GTEx	Skin Sun Exposed Lower leg	ARPC5L	0.11	0.02	lasso	5	0.02	8.8e-03	5.8	5.2	2.4e-07	0.85	0.04	0.92	FALSE
15	GTEx	Thyroid	ARPC5L	0.18	0.12	enet	17	0.16	1.5e-12	5.6	5.2	2.6e-07	0.85	0.05	0.95	FALSE