[Hub]/) : Traits : Hand grip strength (left) :

chr9:126,844,856-128,643,415

Best TWAS P=2.05e-10 · Best GWAS P=9.54e-10 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous GOLGA1 0.04 0.05 lasso 1 0.05 8.6e-05 5.4 5.4 8.2e-08 0.92 0.05 0.93 FALSE
2 GTEx Adipose Subcutaneous SCAI 0.07 0.05 lasso 4 0.02 7.4e-03 5.6 -5.7 1.2e-08 -0.89 0.03 0.97 FALSE
3 GTEx Artery Tibial GOLGA1 0.09 0.09 lasso 4 0.09 7.0e-08 5.4 5.7 9.7e-09 0.85 0.05 0.95 FALSE
4 GTEx Brain Caudate basal ganglia OLFML2A 0.12 0.10 lasso 4 0.03 3.7e-02 5.7 5.6 1.9e-08 0.88 0.03 0.87 FALSE
5 GTEx Brain Cerebellar Hemisphere ARPC5L 0.21 0.34 lasso 2 0.32 6.1e-09 5.5 -5.5 4.0e-08 -0.91 0.05 0.95 FALSE
6 GTEx Brain Cerebellum ARPC5L 0.31 0.37 enet 7 0.27 1.5e-08 5.5 5.6 1.9e-08 0.92 0.04 0.96 FALSE
7 GTEx Colon Transverse GOLGA1 0.10 0.13 lasso 1 0.09 5.9e-05 5.5 5.5 4.5e-08 0.91 0.05 0.95 FALSE
8 GTEx Esophagus Muscularis PPP6C 0.05 0.03 lasso 3 0.01 1.2e-01 5.7 -5.5 3.6e-08 -0.83 0.05 0.67 FALSE
9 GTEx Esophagus Muscularis GOLGA1 0.12 0.05 lasso 9 0.06 2.4e-04 5.5 5.5 3.6e-08 0.88 0.04 0.95 FALSE
10 GTEx Lung GOLGA1 0.10 0.07 lasso 5 0.08 5.7e-07 -4.7 5.5 2.9e-08 0.72 0.11 0.89 FALSE
11 GTEx Muscle Skeletal GOLGA1 0.07 0.02 lasso 4 0.02 2.2e-03 5.7 6.1 1.3e-09 0.88 0.02 0.97 FALSE
12 GTEx Nerve Tibial GOLGA1 0.07 0.04 lasso 2 0.03 5.6e-03 6.1 6.4 2.0e-10 0.95 0.01 0.97 TRUE
13 GTEx Skin Sun Exposed Lower leg ARPC5L 0.11 0.02 lasso 5 0.02 8.8e-03 5.8 5.2 2.4e-07 0.85 0.04 0.92 FALSE
14 GTEx Thyroid GOLGA1 0.07 0.01 lasso 5 0.01 1.0e-01 5.3 5.8 8.7e-09 0.86 0.06 0.82 FALSE
15 GTEx Thyroid ARPC5L 0.18 0.12 enet 17 0.16 1.5e-12 5.6 5.2 2.6e-07 0.85 0.05 0.95 FALSE
16 METSIM Adipose ARPC5L 0.02 0.01 blup 270 0.02 1.5e-03 4.3 5.2 2.2e-07 0.83 0.08 0.84 FALSE
17 ROSMAP Brain Pre-frontal Cortex GOLGA1 0.08 0.07 bslmm 281 0.07 2.3e-09 5.5 5.6 2.4e-08 0.84 0.06 0.94 FALSE
18 The Cancer Genome Atlas Brain Lower Grade Glioma GOLGA1 0.04 0.04 enet 11 0.02 7.2e-04 5.3 5.3 1.4e-07 0.78 0.03 0.82 FALSE
19 The Cancer Genome Atlas Brain Lower Grade Glioma OLFML2A 0.06 0.03 blup 33 0.03 1.6e-04 5.7 -5.5 5.2e-08 -0.74 0.00 0.99 FALSE
20 The Cancer Genome Atlas Brain Lower Grade Glioma SCAI 0.02 0.02 blup 94 0.01 2.1e-02 5.5 -5.5 2.9e-08 -0.88 0.02 0.90 FALSE
21 The Cancer Genome Atlas Thyroid Carcinoma WDR38 0.02 0.02 blup 33 0.02 5.0e-03 4.7 -5.4 8.0e-08 -0.88 0.01 0.81 FALSE