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Traits
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Hand grip strength (left)
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chr10:80,443,273-81,901,722
Best TWAS P=1.87e-09 · Best GWAS P=1.53e-07 conditioned to 0.0126
80.4M
80.6M
80.8M
81M
81.2M
81.4M
81.6M
81.8M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Adipose Subcutaneous
ZCCHC24
0.12
0.01
lasso
6
0.03
3.4e-03
3.6
6.0
1.9e-09
0.52
0.03
0.80
TRUE
2
The Cancer Genome Atlas
Bladder Urothelial Carcinoma
ZCCHC24
0.06
0.00
blup
89
0.01
6.2e-02
3.9
5.6
1.7e-08
0.63
0.00
0.17
FALSE
4
The Cancer Genome Atlas
Brain Lower Grade Glioma
SFTPA2
0.14
0.08
enet
8
0.10
7.6e-12
4.4
-5.6
2.4e-08
-0.77
0.02
0.97
FALSE
3
The Cancer Genome Atlas
Breast Invasive Carcinoma
SFTPA2
0.06
0.03
enet
12
0.04
2.1e-09
3.3
-5.1
2.8e-07
-0.83
0.14
0.76
FALSE