Best TWAS P=1.87e-09 · Best GWAS P=1.53e-07 conditioned to 0.0126
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | ZCCHC24 | 0.12 | 0.01 | lasso | 6 | 0.03 | 3.4e-03 | 3.6 | 6.0 | 1.9e-09 | 0.52 | 0.03 | 0.80 | TRUE |
| 2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | ZCCHC24 | 0.06 | 0.00 | blup | 89 | 0.01 | 6.2e-02 | 3.9 | 5.6 | 1.7e-08 | 0.63 | 0.00 | 0.17 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SFTPA2 | 0.06 | 0.03 | enet | 12 | 0.04 | 2.1e-09 | 3.3 | -5.1 | 2.8e-07 | -0.83 | 0.14 | 0.76 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | SFTPA2 | 0.14 | 0.08 | enet | 8 | 0.10 | 7.6e-12 | 4.4 | -5.6 | 2.4e-08 | -0.77 | 0.02 | 0.97 | FALSE |