[Hub]/) : Traits : Hand grip strength (left) : ← →

chr11:76,602,665-78,216,992

Best TWAS P=6.47e-13 · Best GWAS P=1.15e-10 conditioned to 0.463

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	ROSMAP	Brain Pre-frontal Cortex	AQP11	0.07	0.02	blup	320	0.05	1.5e-06	5.8	-7.2	6.5e-13	0.84	0.04	0.96	TRUE
11	The Cancer Genome Atlas	Brain Lower Grade Glioma	AQP11	0.07	0.01	blup	39	0.03	9.7e-05	-6.3	-6.9	5.0e-12	0.75	0.01	0.94	FALSE
8	GTEx	Thyroid	AP000580.1	0.08	0.04	lasso	3	0.05	1.2e-04	6.3	-6.5	6.8e-11	0.50	0.04	0.90	FALSE
1	CommonMind	Brain Pre-frontal Cortex	AQP11	0.14	0.11	lasso	7	0.13	1.0e-15	-4.7	-6.5	6.9e-11	0.72	0.82	0.18	FALSE
13	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C11orf67	0.08	0.09	lasso	9	0.07	1.0e-03	-6.4	6.4	2.0e-10	-1.00	0.00	0.92	FALSE
7	GTEx	Skin Sun Exposed Lower leg	AP000580.1	0.09	0.09	lasso	4	0.07	1.1e-06	6.1	-6.4	2.1e-10	0.46	0.03	0.97	FALSE
4	GTEx	Breast Mammary Tissue (Male)	AP000580.1	0.31	0.04	lasso	4	0.09	3.6e-03	-5.6	-6.3	3.9e-10	0.84	0.04	0.50	FALSE
3	GTEx	Artery Tibial	AP000580.1	0.12	0.08	lasso	7	0.09	1.1e-07	5.7	-6.1	8.1e-10	0.49	0.08	0.92	FALSE
10	YFS	Blood	AQP11	0.01	0.02	lasso	2	0.02	2.0e-06	-6.1	-6.1	1.1e-09	0.83	0.03	0.97	FALSE
12	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	AQP11	0.04	0.04	lasso	1	0.02	9.5e-03	-6.1	-6.1	1.3e-09	0.82	0.01	0.85	FALSE
14	The Cancer Genome Atlas	Testicular Germ Cell Tumors	AQP11	0.11	0.04	lasso	3	0.06	3.3e-03	-6.3	-5.8	8.6e-09	0.82	0.01	0.90	FALSE
5	GTEx	Cells Transformed fibroblasts	AP000580.1	0.12	0.02	enet	18	0.08	1.1e-06	6.3	-5.7	1.3e-08	0.52	0.02	0.98	FALSE
6	GTEx	Muscle Skeletal	AQP11	0.10	0.08	lasso	4	0.09	4.7e-09	-4.7	-5.4	6.2e-08	0.67	0.96	0.04	FALSE
2	GTEx	Adipose Subcutaneous	AP000580.1	0.06	0.05	lasso	4	0.06	1.4e-05	5.7	-5.1	2.9e-07	0.42	0.19	0.78	FALSE