[Hub]/) : Traits : Hand grip strength (left) : ← →

chr11:76,602,665-78,216,992

Best TWAS P=6.47e-13 · Best GWAS P=1.15e-10 conditioned to 0.463

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex AQP11 0.14 0.11 lasso 7 0.13 1.0e-15 -4.7 -6.5 6.9e-11 0.72 0.82 0.18 FALSE
2 GTEx Adipose Subcutaneous AP000580.1 0.06 0.05 lasso 4 0.06 1.4e-05 5.7 -5.1 2.9e-07 0.42 0.19 0.78 FALSE
3 GTEx Artery Tibial AP000580.1 0.12 0.08 lasso 7 0.09 1.1e-07 5.7 -6.1 8.1e-10 0.49 0.08 0.92 FALSE
4 GTEx Breast Mammary Tissue (Male) AP000580.1 0.31 0.04 lasso 4 0.09 3.6e-03 -5.6 -6.3 3.9e-10 0.84 0.04 0.50 FALSE
5 GTEx Cells Transformed fibroblasts AP000580.1 0.12 0.02 enet 18 0.08 1.1e-06 6.3 -5.7 1.3e-08 0.52 0.02 0.98 FALSE
6 GTEx Muscle Skeletal AQP11 0.10 0.08 lasso 4 0.09 4.7e-09 -4.7 -5.4 6.2e-08 0.67 0.96 0.04 FALSE
7 GTEx Skin Sun Exposed Lower leg AP000580.1 0.09 0.09 lasso 4 0.07 1.1e-06 6.1 -6.4 2.1e-10 0.46 0.03 0.97 FALSE
8 GTEx Thyroid AP000580.1 0.08 0.04 lasso 3 0.05 1.2e-04 6.3 -6.5 6.8e-11 0.50 0.04 0.90 FALSE
9 ROSMAP Brain Pre-frontal Cortex AQP11 0.07 0.02 blup 320 0.05 1.5e-06 5.8 -7.2 6.5e-13 0.84 0.04 0.96 TRUE
10 YFS Blood AQP11 0.01 0.02 lasso 2 0.02 2.0e-06 -6.1 -6.1 1.1e-09 0.83 0.03 0.97 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma AQP11 0.07 0.01 blup 39 0.03 9.7e-05 -6.3 -6.9 5.0e-12 0.75 0.01 0.94 FALSE
12 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma AQP11 0.04 0.04 lasso 1 0.02 9.5e-03 -6.1 -6.1 1.3e-09 0.82 0.01 0.85 FALSE
13 The Cancer Genome Atlas Pancreatic Adenocarcinoma C11orf67 0.08 0.09 lasso 9 0.07 1.0e-03 -6.4 6.4 2.0e-10 -1.00 0.00 0.92 FALSE
14 The Cancer Genome Atlas Testicular Germ Cell Tumors AQP11 0.11 0.04 lasso 3 0.06 3.3e-03 -6.3 -5.8 8.6e-09 0.82 0.01 0.90 FALSE