[Hub]/) : Traits : Hand grip strength (left) : ← →

chr11:73,024,914-75,075,866

Best TWAS P=2.21e-15 · Best GWAS P=2.52e-17 conditioned to 0.699

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	The Cancer Genome Atlas	Breast Invasive Carcinoma	POLD3	0.02	0.01	lasso	3	0.01	0.0018	6.8	-7.9	2.2e-15	-0.65	0.08	0.17	TRUE
2	GTEx	Testis	POLD3	0.18	-0.01	enet	48	0.00	0.2900	1.8	-6.3	3.4e-10	-0.58	0.02	0.73	TRUE
3	ROSMAP	Brain Pre-frontal Cortex	C2CD3	0.04	0.01	blup	446	0.02	0.0021	2.2	5.2	1.8e-07	0.33	0.21	0.28	TRUE
1	GTEx	Cells Transformed fibroblasts	AP001372.2	0.10	0.02	enet	13	0.05	0.0002	-1.2	5.7	1.0e-08	0.48	0.14	0.34	FALSE
5	The Cancer Genome Atlas	Thyroid Carcinoma	POLD3	0.03	0.00	blup	77	0.01	0.0133	7.0	-5.2	1.9e-07	-0.32	0.04	0.07	FALSE