[Hub]/) : Traits : Hand grip strength (left) :

chr17:36,211,659-37,644,854

Best TWAS P=6.66e-15 · Best GWAS P=9.56e-15 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PSMB3 0.11 0.01 enet 8 0.03 2.7e-03 -5.7 -5.9 4.8e-09 0.68 0.01 0.94 FALSE
2 GTEx Adipose Subcutaneous PIP4K2B 0.15 0.07 lasso 5 0.07 2.2e-06 -7.7 -7.3 2.3e-13 0.92 0.00 1.00 FALSE
3 GTEx Artery Aorta PSMB3 0.23 0.17 enet 26 0.22 2.1e-12 -7.7 -6.4 1.2e-10 0.83 0.00 1.00 FALSE
4 GTEx Artery Tibial PSMB3 0.10 0.02 enet 12 0.03 1.2e-03 -7.7 -6.3 3.3e-10 0.73 0.01 0.99 FALSE
5 GTEx Artery Tibial PIP4K2B 0.37 0.16 enet 49 0.22 2.1e-17 -7.7 -7.5 7.1e-14 0.73 0.00 1.00 FALSE
6 GTEx Testis PSMB3 0.30 0.24 lasso 4 0.21 8.9e-10 -7.7 -7.8 6.7e-15 0.97 0.00 1.00 TRUE
7 METSIM Adipose PIP4K2B 0.06 0.01 blup 360 0.02 7.0e-04 -4.3 -5.6 1.8e-08 0.49 0.01 0.98 FALSE
8 NTR Blood PIP4K2B 0.02 0.01 lasso 3 0.01 6.4e-04 -7.7 7.2 5.6e-13 -0.94 0.00 0.99 FALSE
9 YFS Blood PSMB3 0.14 0.11 enet 31 0.16 7.2e-49 -7.7 -6.2 4.4e-10 0.82 0.00 1.00 FALSE
10 The Cancer Genome Atlas Bladder Urothelial Carcinoma PSMB3 0.04 0.00 blup 37 0.02 6.7e-03 -4.3 -6.3 2.2e-10 0.73 0.01 0.73 FALSE
11 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PIP4K2B 0.04 0.01 blup 56 0.03 6.3e-04 -7.7 -5.8 6.3e-09 0.84 0.00 0.95 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PSMB3 0.14 0.05 blup 42 0.05 8.9e-07 -7.7 -6.0 2.1e-09 0.69 0.00 1.00 FALSE
13 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PSMB3 0.12 0.02 enet 14 0.05 1.3e-03 -6.6 -6.1 1.1e-09 0.64 0.00 0.83 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma PIP4K2B 0.05 0.04 blup 56 0.05 5.3e-06 -6.6 -7.4 1.2e-13 0.85 0.00 0.99 FALSE
15 The Cancer Genome Atlas Prostate Adenocarcinoma PSMB3 0.11 0.07 blup 42 0.07 9.4e-08 -7.7 -6.8 1.3e-11 0.76 0.00 1.00 FALSE
16 The Cancer Genome Atlas Testicular Germ Cell Tumors PSMB3 0.12 0.09 lasso 3 0.06 3.0e-03 -7.7 -7.7 1.8e-14 0.99 0.00 0.94 FALSE
17 The Cancer Genome Atlas Thyroid Carcinoma PSMB3 0.05 0.06 lasso 1 0.05 2.4e-05 -7.7 -7.7 1.7e-14 0.97 0.00 1.00 FALSE