Best TWAS P=2.24e-10 · Best GWAS P=2.54e-12 conditioned to 0.0198
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adrenal Gland | DYM | 0.30 | 0.01 | enet | 15 | 0.01 | 1.2e-01 | 6.6 | 5.9 | 4.3e-09 | 0.80 | 0.03 | 0.81 | FALSE |
2 | GTEx | Esophagus Mucosa | DYM | 0.12 | 0.01 | enet | 12 | 0.04 | 1.0e-03 | 6.6 | 5.7 | 1.4e-08 | 0.67 | 0.03 | 0.93 | FALSE |
3 | YFS | Blood | DYM | 0.05 | 0.05 | lasso | 4 | 0.04 | 1.5e-13 | -5.3 | 6.3 | 2.2e-10 | 0.74 | 0.84 | 0.16 | TRUE |
4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | C18orf32 | 0.04 | 0.03 | blup | 48 | 0.04 | 6.5e-05 | 3.9 | 5.2 | 2.1e-07 | 0.57 | 0.10 | 0.75 | TRUE |