TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Hand grip strength (right)
:
←
→
chr6:33,856,903-35,362,848
Best TWAS P=7.3e-10 · Best GWAS P=6.56e-07 conditioned to 0.00153
33.8M
34M
34.2M
34.4M
34.6M
34.8M
35M
35.2M
35.4M
0
1
2
3
4
5
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Thyroid Carcinoma
C6orf106
0.08
0.00
enet
15
0.05
2.5e-05
-4.0
6.2
7.3e-10
-0.32
0.00
0.07
TRUE
2
ROSMAP
Brain Pre-frontal Cortex
C6orf106
0.30
0.26
bslmm
372
0.33
9.3e-44
3.9
5.6
2.6e-08
-0.31
0.22
0.53
FALSE
1
GTEx
Skin Sun Exposed Lower leg
C6orf106
0.09
0.04
enet
25
0.02
4.6e-03
-3.8
5.2
1.6e-07
-0.34
0.12
0.32
FALSE