Best TWAS P=7.3e-10 · Best GWAS P=6.56e-07 conditioned to 0.00153
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | C6orf106 | 0.09 | 0.04 | enet | 25 | 0.02 | 4.6e-03 | -3.8 | 5.2 | 1.6e-07 | -0.34 | 0.12 | 0.32 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | C6orf106 | 0.30 | 0.26 | bslmm | 372 | 0.33 | 9.3e-44 | 3.9 | 5.6 | 2.6e-08 | -0.31 | 0.22 | 0.53 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | C6orf106 | 0.08 | 0.00 | enet | 15 | 0.05 | 2.5e-05 | -4.0 | 6.2 | 7.3e-10 | -0.32 | 0.00 | 0.07 | TRUE |