Best TWAS P=1.96e-09 · Best GWAS P=2.17e-06 conditioned to 0.856
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Coronary | BCKDHB | 0.29 | 0.05 | lasso | 27 | 0.11 | 1.7e-04 | 4.5 | 6.0 | 2.0e-09 | 0.62 | 0.04 | 0.80 | TRUE |
| 2 | GTEx | Cells EBV-transformed lymphocytes | RP11-250B2.6 | 0.21 | 0.03 | enet | 37 | 0.13 | 4.7e-05 | 4.5 | -5.5 | 3.8e-08 | -0.57 | 0.03 | 0.60 | TRUE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | RP11-250B2.6 | 0.08 | 0.05 | lasso | 4 | 0.01 | 8.1e-02 | 4.7 | -5.5 | 3.2e-08 | -0.94 | 0.02 | 0.79 | FALSE |