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Hand grip strength (right)
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chr6:80,120,201-81,763,771
Best TWAS P=1.96e-09 · Best GWAS P=2.17e-06 conditioned to 0.856
80.2M
80.4M
80.6M
80.8M
81M
81.2M
81.4M
81.6M
81.8M
0
1
2
3
4
5
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Artery Coronary
BCKDHB
0.29
0.05
lasso
27
0.11
1.7e-04
4.5
6.0
2.0e-09
0.62
0.04
0.80
TRUE
2
GTEx
Cells EBV-transformed lymphocytes
RP11-250B2.6
0.21
0.03
enet
37
0.13
4.7e-05
4.5
-5.5
3.8e-08
-0.57
0.03
0.60
TRUE
3
GTEx
Skin Not Sun Exposed Suprapubic
RP11-250B2.6
0.08
0.05
lasso
4
0.01
8.1e-02
4.7
-5.5
3.2e-08
-0.94
0.02
0.79
FALSE