[Hub]/) : Traits : Hand grip strength (right) : ← →

chr6:129,638,583-131,163,098

Best TWAS P=2.73e-20 · Best GWAS P=9.41e-18 conditioned to 0.85

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	L3MBTL3	0.20	0.08	lasso	4	0.09	1.1e-07	8.6	9.2	2.7e-20	0.94	0.00	1.00	TRUE
31	GTEx	Whole Blood	RP11-73O6.3	0.15	0.06	lasso	8	0.04	1.1e-04	8.6	9.2	4.2e-20	0.97	0.00	1.00	FALSE
28	GTEx	Thyroid	L3MBTL3	0.40	0.39	enet	9	0.43	2.8e-35	8.6	9.0	2.3e-19	0.95	0.00	1.00	FALSE
3	GTEx	Breast Mammary Tissue	L3MBTL3	0.31	0.25	lasso	7	0.23	2.8e-12	8.6	9.0	2.5e-19	0.97	0.00	1.00	FALSE
2	GTEx	Adipose Visceral Omentum	L3MBTL3	0.14	0.12	lasso	2	0.15	2.8e-08	8.6	9.0	2.7e-19	0.94	0.00	1.00	FALSE
13	GTEx	Lung	L3MBTL3	0.37	0.34	lasso	4	0.38	4.1e-30	8.6	9.0	2.8e-19	0.96	0.00	1.00	FALSE
7	GTEx	Breast Mammary Tissue (Female)	L3MBTL3	0.30	0.13	lasso	5	0.14	4.5e-05	7.4	8.9	3.6e-19	0.93	0.01	0.98	FALSE
14	GTEx	Lung	RP11-73O6.3	0.15	0.08	lasso	5	0.12	2.2e-09	8.6	8.9	4.0e-19	0.93	0.00	1.00	FALSE
16	GTEx	Pancreas	L3MBTL3	0.32	0.17	lasso	4	0.23	4.4e-10	8.6	8.9	4.2e-19	0.98	0.00	1.00	FALSE
29	GTEx	Thyroid	RP11-73O6.3	0.18	0.15	lasso	3	0.20	2.3e-15	7.8	8.9	4.6e-19	0.91	0.00	1.00	FALSE
15	GTEx	Nerve Tibial	L3MBTL3	0.30	0.23	lasso	4	0.22	2.3e-15	8.6	8.9	6.4e-19	0.99	0.00	1.00	FALSE
9	GTEx	Cells EBV-transformed lymphocytes	L3MBTL3	0.28	0.08	lasso	10	0.03	4.4e-02	8.6	8.8	1.1e-18	0.85	0.01	0.97	FALSE
4	GTEx	Breast Mammary Tissue	RP11-73O6.3	0.27	0.22	lasso	9	0.22	1.5e-11	8.6	8.8	1.8e-18	0.97	0.00	1.00	FALSE
6	GTEx	Breast Mammary Tissue (Male)	RP11-73O6.3	0.33	0.17	lasso	4	0.12	1.3e-03	8.6	8.8	1.8e-18	0.94	0.01	0.96	FALSE
21	GTEx	Skin Sun Exposed Lower leg	L3MBTL3	0.25	0.25	lasso	9	0.24	1.4e-19	8.6	8.7	2.3e-18	0.97	0.00	1.00	FALSE
19	GTEx	Prostate	L3MBTL3	0.35	0.27	lasso	5	0.17	5.9e-05	8.6	8.7	2.7e-18	0.97	0.00	0.99	FALSE
11	GTEx	Colon Transverse	RP11-73O6.3	0.19	0.09	lasso	2	0.06	1.2e-03	8.6	8.7	3.2e-18	0.99	0.00	1.00	FALSE
30	GTEx	Whole Blood	L3MBTL3	0.22	0.20	lasso	9	0.20	5.1e-18	8.6	8.7	3.2e-18	0.98	0.00	1.00	FALSE
23	GTEx	Spleen	L3MBTL3	0.64	0.34	enet	14	0.48	6.4e-14	7.3	8.7	3.4e-18	0.87	0.02	0.98	FALSE
8	GTEx	Breast Mammary Tissue (Female)	RP11-73O6.3	0.29	0.08	lasso	5	0.10	5.7e-04	7.3	8.7	3.6e-18	0.90	0.01	0.97	FALSE
5	GTEx	Breast Mammary Tissue (Male)	L3MBTL3	0.31	0.24	lasso	6	0.23	5.5e-06	8.6	8.6	5.7e-18	0.94	0.00	0.98	FALSE
24	GTEx	Spleen	RP11-73O6.3	0.45	0.43	enet	21	0.42	7.7e-12	7.3	8.6	6.3e-18	0.82	0.05	0.95	FALSE
12	GTEx	Esophagus Mucosa	L3MBTL3	0.26	0.18	lasso	2	0.23	2.7e-15	7.3	8.5	1.3e-17	0.93	0.00	1.00	FALSE
22	GTEx	Small Intestine Terminal Ileum	L3MBTL3	0.37	0.20	lasso	4	0.17	1.3e-04	8.6	8.4	5.1e-17	0.98	0.00	0.98	FALSE
20	GTEx	Skin Not Sun Exposed Suprapubic	L3MBTL3	0.26	0.12	lasso	4	0.12	4.0e-07	6.5	8.2	2.1e-16	0.92	0.00	1.00	FALSE
25	GTEx	Stomach	L3MBTL3	0.36	0.18	enet	27	0.20	1.1e-09	8.1	8.2	2.1e-16	0.77	0.02	0.98	FALSE
17	GTEx	Pituitary	L3MBTL3	0.45	0.31	lasso	8	0.29	5.1e-08	7.4	8.1	3.9e-16	0.85	0.01	0.99	FALSE
10	GTEx	Colon Transverse	L3MBTL3	0.27	0.13	lasso	8	0.20	8.0e-10	8.6	8.1	7.8e-16	0.88	0.00	1.00	FALSE
34	YFS	Blood	L3MBTL3	0.28	0.22	blup	614	0.27	1.2e-88	7.3	8.0	1.4e-15	0.74	0.97	0.03	FALSE
33	ROSMAP	Brain Pre-frontal Cortex	L3MBTL3	0.14	0.07	blup	609	0.08	3.8e-10	8.6	8.0	1.5e-15	0.72	0.00	1.00	FALSE
27	GTEx	Testis	L3MBTL3	0.41	0.22	lasso	8	0.30	9.2e-14	8.6	7.5	6.1e-14	0.90	0.00	1.00	FALSE
18	GTEx	Pituitary	RP11-73O6.3	0.48	0.07	lasso	7	0.16	8.2e-05	7.4	7.5	7.3e-14	0.78	0.01	0.98	FALSE
26	GTEx	Stomach	RP11-73O6.3	0.21	0.12	lasso	6	0.06	5.9e-04	8.1	7.2	7.3e-13	0.73	0.06	0.80	FALSE
32	METSIM	Adipose	L3MBTL3	0.13	0.12	enet	22	0.12	4.8e-18	7.3	7.0	3.3e-12	0.72	0.94	0.06	FALSE
35	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	L3MBTL3	0.06	0.01	blup	114	0.04	4.0e-03	7.3	6.2	6.5e-10	0.77	0.02	0.86	FALSE