Best TWAS P=9.46e-09 · Best GWAS P=2.7e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | HABP4 | 0.19 | 0.22 | lasso | 9 | 0.21 | 1.1e-09 | 5.3 | 5.3 | 1.2e-07 | 0.99 | 0.03 | 0.97 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CDC14B | 0.02 | 0.01 | lasso | 1 | 0.01 | 3.0e-03 | 5.3 | -5.3 | 1.1e-07 | -0.98 | 0.02 | 0.74 | FALSE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | HABP4 | 0.02 | 0.02 | blup | 44 | 0.02 | 7.1e-03 | 5.3 | 5.5 | 4.0e-08 | 0.98 | 0.02 | 0.79 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CDC14B | 0.03 | 0.02 | blup | 42 | 0.02 | 2.1e-03 | 5.3 | -5.7 | 9.5e-09 | -0.96 | 0.01 | 0.85 | TRUE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CDC14B | 0.05 | 0.06 | lasso | 5 | 0.06 | 6.5e-07 | 5.5 | -5.2 | 1.7e-07 | -0.98 | 0.01 | 0.99 | FALSE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | HABP4 | 0.05 | 0.08 | lasso | 5 | 0.08 | 6.9e-09 | 5.1 | -5.3 | 1.4e-07 | -0.97 | 0.03 | 0.97 | FALSE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | CDC14B | 0.05 | 0.07 | blup | 42 | 0.08 | 4.8e-08 | 5.3 | -5.6 | 2.1e-08 | -0.97 | 0.02 | 0.98 | FALSE |