[Hub]/) : Traits : Hand grip strength (right) : ← →

chr9:126,844,856-128,680,148

Best TWAS P=4.08e-09 · Best GWAS P=1.68e-08 conditioned to 0.443

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Adipose Subcutaneous	SCAI	0.07	0.05	lasso	4	0.02	7.4e-03	5.5	-5.9	4.1e-09	-0.90	0.04	0.95	TRUE
11	GTEx	Muscle Skeletal	GOLGA1	0.07	0.02	lasso	4	0.02	2.2e-03	5.4	5.6	1.7e-08	0.87	0.06	0.91	FALSE
20	The Cancer Genome Atlas	Brain Lower Grade Glioma	SCAI	0.02	0.02	blup	94	0.01	2.1e-02	5.2	-5.6	1.8e-08	-0.90	0.03	0.82	FALSE
14	GTEx	Spleen	PRPS1P2	0.18	0.02	lasso	4	0.04	3.9e-02	4.9	5.6	1.9e-08	0.79	0.09	0.26	FALSE
15	GTEx	Thyroid	ARPC5L	0.18	0.12	enet	17	0.16	1.5e-12	5.5	5.5	4.4e-08	0.84	0.04	0.96	FALSE
12	GTEx	Nerve Tibial	GOLGA1	0.07	0.04	lasso	2	0.03	5.6e-03	5.6	5.5	4.8e-08	0.75	0.03	0.85	FALSE
9	GTEx	Esophagus Muscularis	PPP6C	0.05	0.03	lasso	3	0.01	1.2e-01	5.4	-5.4	7.0e-08	-0.80	0.06	0.59	FALSE
19	The Cancer Genome Atlas	Brain Lower Grade Glioma	OLFML2A	0.06	0.03	blup	33	0.03	1.6e-04	5.4	-5.4	7.6e-08	-0.71	0.00	0.99	FALSE
4	GTEx	Brain Caudate basal ganglia	OLFML2A	0.12	0.10	lasso	4	0.03	3.7e-02	5.4	5.3	9.5e-08	0.82	0.04	0.82	FALSE
6	GTEx	Brain Cerebellum	ARPC5L	0.31	0.37	enet	7	0.27	1.5e-08	5.3	5.3	9.8e-08	0.84	0.05	0.95	FALSE
16	METSIM	Adipose	ARPC5L	0.02	0.01	blup	270	0.02	1.5e-03	4.9	5.3	1.2e-07	0.90	0.06	0.88	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	GOLGA1	0.08	0.07	bslmm	281	0.07	2.3e-09	5.2	5.3	1.2e-07	0.82	0.06	0.94	FALSE
5	GTEx	Brain Cerebellar Hemisphere	ARPC5L	0.21	0.34	lasso	2	0.32	6.1e-09	5.2	-5.2	1.7e-07	-0.84	0.06	0.94	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	PPP6C	0.11	0.19	lasso	5	0.20	8.6e-26	5.0	-5.2	1.7e-07	-0.85	0.21	0.78	FALSE
10	GTEx	Esophagus Muscularis	RABEPK	0.12	0.01	enet	19	0.08	1.3e-05	-4.1	-5.2	1.8e-07	-0.61	0.10	0.70	FALSE
8	GTEx	Colon Transverse	GOLGA1	0.10	0.13	lasso	1	0.09	5.9e-05	5.2	5.2	2.0e-07	0.84	0.07	0.92	FALSE
1	CommonMind	Brain Pre-frontal Cortex	SCAI	0.04	0.00	enet	8	0.02	4.2e-03	1.9	-5.2	2.1e-07	-0.61	0.07	0.67	FALSE
2	GTEx	Adipose Subcutaneous	GOLGA1	0.04	0.05	lasso	1	0.05	8.6e-05	5.2	5.2	2.5e-07	0.85	0.06	0.91	FALSE
13	GTEx	Skin Sun Exposed Lower leg	PPP6C	0.11	0.10	lasso	5	0.09	9.1e-08	5.0	-5.1	3.0e-07	-0.83	0.21	0.79	FALSE
7	GTEx	Cells EBV-transformed lymphocytes	GOLGA1	0.13	0.00	enet	8	0.06	3.8e-03	3.7	5.1	3.1e-07	0.74	0.26	0.40	FALSE