[Hub]/) : Traits : Hand grip strength (right) :

chr9:126,844,856-128,680,148

Best TWAS P=4.08e-09 · Best GWAS P=1.68e-08 conditioned to 0.443

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SCAI 0.04 0.00 enet 8 0.02 4.2e-03 1.9 -5.2 2.1e-07 -0.61 0.07 0.67 FALSE
2 GTEx Adipose Subcutaneous GOLGA1 0.04 0.05 lasso 1 0.05 8.6e-05 5.2 5.2 2.5e-07 0.85 0.06 0.91 FALSE
3 GTEx Adipose Subcutaneous SCAI 0.07 0.05 lasso 4 0.02 7.4e-03 5.5 -5.9 4.1e-09 -0.90 0.04 0.95 TRUE
4 GTEx Brain Caudate basal ganglia OLFML2A 0.12 0.10 lasso 4 0.03 3.7e-02 5.4 5.3 9.5e-08 0.82 0.04 0.82 FALSE
5 GTEx Brain Cerebellar Hemisphere ARPC5L 0.21 0.34 lasso 2 0.32 6.1e-09 5.2 -5.2 1.7e-07 -0.84 0.06 0.94 FALSE
6 GTEx Brain Cerebellum ARPC5L 0.31 0.37 enet 7 0.27 1.5e-08 5.3 5.3 9.8e-08 0.84 0.05 0.95 FALSE
7 GTEx Cells EBV-transformed lymphocytes GOLGA1 0.13 0.00 enet 8 0.06 3.8e-03 3.7 5.1 3.1e-07 0.74 0.26 0.40 FALSE
8 GTEx Colon Transverse GOLGA1 0.10 0.13 lasso 1 0.09 5.9e-05 5.2 5.2 2.0e-07 0.84 0.07 0.92 FALSE
9 GTEx Esophagus Muscularis PPP6C 0.05 0.03 lasso 3 0.01 1.2e-01 5.4 -5.4 7.0e-08 -0.80 0.06 0.59 FALSE
10 GTEx Esophagus Muscularis RABEPK 0.12 0.01 enet 19 0.08 1.3e-05 -4.1 -5.2 1.8e-07 -0.61 0.10 0.70 FALSE
11 GTEx Muscle Skeletal GOLGA1 0.07 0.02 lasso 4 0.02 2.2e-03 5.4 5.6 1.7e-08 0.87 0.06 0.91 FALSE
12 GTEx Nerve Tibial GOLGA1 0.07 0.04 lasso 2 0.03 5.6e-03 5.6 5.5 4.8e-08 0.75 0.03 0.85 FALSE
13 GTEx Skin Sun Exposed Lower leg PPP6C 0.11 0.10 lasso 5 0.09 9.1e-08 5.0 -5.1 3.0e-07 -0.83 0.21 0.79 FALSE
14 GTEx Spleen PRPS1P2 0.18 0.02 lasso 4 0.04 3.9e-02 4.9 5.6 1.9e-08 0.79 0.09 0.26 FALSE
15 GTEx Thyroid ARPC5L 0.18 0.12 enet 17 0.16 1.5e-12 5.5 5.5 4.4e-08 0.84 0.04 0.96 FALSE
16 METSIM Adipose ARPC5L 0.02 0.01 blup 270 0.02 1.5e-03 4.9 5.3 1.2e-07 0.90 0.06 0.88 FALSE
17 ROSMAP Brain Pre-frontal Cortex PPP6C 0.11 0.19 lasso 5 0.20 8.6e-26 5.0 -5.2 1.7e-07 -0.85 0.21 0.78 FALSE
18 ROSMAP Brain Pre-frontal Cortex GOLGA1 0.08 0.07 bslmm 281 0.07 2.3e-09 5.2 5.3 1.2e-07 0.82 0.06 0.94 FALSE
19 The Cancer Genome Atlas Brain Lower Grade Glioma OLFML2A 0.06 0.03 blup 33 0.03 1.6e-04 5.4 -5.4 7.6e-08 -0.71 0.00 0.99 FALSE
20 The Cancer Genome Atlas Brain Lower Grade Glioma SCAI 0.02 0.02 blup 94 0.01 2.1e-02 5.2 -5.6 1.8e-08 -0.90 0.03 0.82 FALSE