Best TWAS P=9.22e-08 · Best GWAS P=1.59e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | BRD3 | 0.21 | 0.01 | lasso | 5 | 0.00 | 1.8e-01 | 5.1 | -5.1 | 3.0e-07 | -0.91 | 0.01 | 0.82 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | BRD3 | 0.29 | 0.23 | lasso | 4 | 0.27 | 3.7e-20 | 5.2 | -5.3 | 9.2e-08 | -0.96 | 0.00 | 1.00 | TRUE |
| 3 | GTEx | Skin Sun Exposed Lower leg | BRD3 | 0.18 | 0.12 | lasso | 7 | 0.11 | 1.2e-09 | 3.9 | -5.1 | 2.9e-07 | -0.73 | 0.09 | 0.88 | FALSE |