Best TWAS P=9.56e-09 · Best GWAS P=1.27e-06 conditioned to 0.217
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Frontal Cortex BA9 | TMEM106C | 0.35 | 0.01 | lasso | 8 | -0.01 | 0.6790 | 4.2 | -5.7 | 9.6e-09 | 0.69 | 0.02 | 0.51 | TRUE |
2 | GTEx | Liver | RP1-228P16.1 | 0.19 | 0.08 | lasso | 7 | 0.06 | 0.0071 | -4.6 | 5.2 | 1.6e-07 | -0.48 | 0.04 | 0.63 | FALSE |