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Hand grip strength (right)
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chr12:47,671,905-49,133,725
Best TWAS P=9.56e-09 · Best GWAS P=1.27e-06 conditioned to 0.217
47.6M
47.8M
48M
48.2M
48.4M
48.6M
48.8M
49M
49.2M
0
1
2
3
4
5
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Brain Frontal Cortex BA9
TMEM106C
0.35
0.01
lasso
8
-0.01
0.6790
4.2
-5.7
9.6e-09
0.69
0.02
0.51
TRUE
2
GTEx
Liver
RP1-228P16.1
0.19
0.08
lasso
7
0.06
0.0071
-4.6
5.2
1.6e-07
-0.48
0.04
0.63
FALSE