TWAS hub - TMEM106C

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1300	0.0370	2.9e-08	0.061	0.082	0.109	0.091	0.089	5.6e-08	3.7e-10	3.2e-13	3.7e-11	5.1e-11
2	GTEx	Artery Tibial	0.1918	0.0578	5.9e-05	0.121	NA	0.145	NA	0.129	1.1e-09	NA	2.0e-11	NA	2.7e-10
3	GTEx	Brain Caudate basal ganglia	0.4730	0.1050	4.2e-04	0.004	NA	0.026	NA	0.032	2.3e-01	NA	6.0e-02	NA	4.2e-02
4	GTEx	Brain Cortex	0.2050	0.0730	1.6e-03	0.035	NA	0.100	NA	0.078	3.8e-02	NA	1.1e-03	NA	3.6e-03
5	GTEx	Brain Frontal Cortex BA9	0.3456	0.1025	6.1e-04	0.014	NA	-0.010	NA	-0.009	1.4e-01	NA	7.4e-01	NA	6.8e-01
6	GTEx	Cells Transformed fibroblasts	0.3290	0.0620	3.5e-09	0.168	NA	0.125	NA	0.130	1.3e-12	NA	1.2e-09	NA	6.1e-10
7	GTEx	Esophagus Mucosa	0.0880	0.0370	6.2e-03	0.020	NA	0.032	NA	0.026	1.7e-02	NA	3.3e-03	NA	7.0e-03
8	GTEx	Esophagus Muscularis	0.2900	0.0740	5.1e-05	0.011	NA	0.009	NA	0.033	6.7e-02	NA	9.2e-02	NA	4.2e-03
9	GTEx	Heart Left Ventricle	0.1049	0.0458	5.8e-03	-0.002	NA	-0.005	NA	-0.005	4.4e-01	NA	8.1e-01	NA	9.4e-01
10	GTEx	Skin Sun Exposed Lower leg	0.1830	0.0650	6.6e-04	0.100	NA	0.069	NA	0.092	1.2e-08	NA	2.3e-06	NA	4.7e-08
11	NTR	Blood	0.0278	0.0115	1.3e-03	0.009	0.008	0.019	0.016	0.018	5.5e-04	8.1e-04	5.4e-07	6.0e-06	9.0e-07
12	YFS	Blood	0.0637	0.0184	1.5e-08	0.040	0.029	0.033	0.034	0.034	5.2e-13	7.9e-10	3.9e-11	2.4e-11	1.8e-11
13	TCGA	Head and Neck Squamous Cell Carcinoma	0.0518	0.0301	8.0e-03	0.039	0.011	0.024	NA	0.026	3.2e-05	1.9e-02	8.6e-04	NA	5.9e-04
14	TCGA	Lung Adenocarcinoma	0.0443	0.0245	7.6e-03	0.013	0.022	0.021	NA	0.020	9.4e-03	1.3e-03	1.3e-03	NA	2.0e-03
15	TCGA	Ovarian Serous Cystadenocarcinoma	0.0850	0.0480	6.5e-03	0.004	0.037	0.015	NA	-0.003	1.6e-01	1.5e-03	3.0e-02	NA	5.7e-01
16	TCGA	Pheochromocytoma and Paraganglioma	0.2680	0.1070	1.9e-03	0.097	0.039	0.050	NA	0.091	1.1e-04	1.1e-02	4.6e-03	NA	1.7e-04
17	TCGA	Prostate Adenocarcinoma	0.0471	0.0217	8.1e-05	0.011	0.034	0.004	NA	0.014	2.0e-02	1.5e-04	1.1e-01	NA	1.1e-02
18	TCGA	Thyroid Carcinoma	0.0750	0.0340	5.4e-04	0.008	0.040	0.046	NA	0.036	5.4e-02	7.9e-05	2.4e-05	NA	1.9e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
High blood pressure (mother)	5.8	8.1	30.9	3.9	1.7	3.0	5.6	4.4	-3.5	-1.1	2.4	2.1	-2.2	1.7	1.4	-3.7	-0.6	-4.2	0.4	-1.0	1.7
Eye problems/disorders: None of the above	5.1	5.9	17.0	2.0	2.6	2.3	1.3	0.0	-3.1	-2.2	3.2	4.1	-1.0	3.4	3.0	-2.5	2.6	-0.0	0.2	3.0	1.8
Impedance of arm (right)	4.1	19.0	73.9	5.7	4.2	2.6	7.1	8.6	-2.9	0.8	3.7	1.0	3.6	1.7	2.2	-2.7	-2.5	-4.0	6.4	-3.5	5.8
Impedance of leg (right)	3.7	18.0	89.9	5.2	1.8	1.6	5.9	9.5	-1.5	3.2	3.0	-0.5	3.8	0.6	0.9	-1.7	-4.7	-5.4	6.4	-3.4	4.7
Medication: Blood pressure	3.6	6.3	19.0	4.4	1.6	2.3	3.3	3.7	-4.0	-1.6	1.0	0.3	-2.4	1.2	-0.4	-4.0	-1.4	-3.6	-0.3	-1.9	1.4
Knee pain experienced in last month	3.6	5.6	19.5	1.8	-1.2	-0.5	1.9	4.3	-1.8	-0.9	-0.2	-1.8	-2.5	-1.3	-3.6	-2.0	-3.7	-4.4	-1.6	-2.3	-1.0
Illnesses of mother	3.3	4.1	10.2	-2.3	-0.5	-2.0	-3.1	-2.8	2.8	1.6	-1.2	-1.2	3.2	-1.1	0.3	3.0	1.4	2.8	1.6	0.7	-0.0
Impedance of whole body	3.2	16.3	80.7	4.9	2.6	1.7	6.1	9.0	-1.3	2.7	2.7	-0.1	3.8	0.5	1.2	-1.4	-3.4	-4.6	6.4	-3.6	4.6
Impedance of arm (left)	3.1	14.2	59.2	4.8	3.5	2.3	6.4	7.7	-2.2	0.8	2.8	0.7	2.9	1.2	2.0	-2.1	-2.1	-4.0	5.5	-3.1	4.8
Medication for cholesterol, blood pressure or diabetes	2.9	4.7	17.4	-4.0	0.1	-1.2	-2.6	-4.2	2.7	0.1	-1.1	0.5	1.9	0.0	1.1	2.7	2.0	3.7	-0.2	2.3	-0.8
Medication: Aspirin	2.9	3.8	9.6	2.6	1.2	2.1	2.3	1.9	-3.1	-1.3	2.8	2.1	-1.0	2.0	1.0	-3.1	-0.8	-1.8	0.6	0.6	2.1
Blood Red Count	2.8	27.4	192.2	-6.2	0.1	-1.5	-7.2	-13.9	1.8	-3.5	-0.3	2.1	3.1	3.0	3.0	2.4	6.4	10.0	-0.9	3.5	1.5
Overall health rating	2.8	6.1	22.7	2.7	-0.6	0.6	0.9	4.8	-1.0	0.0	-1.0	-2.8	-2.5	-1.6	-3.8	-2.0	-2.6	-4.1	-1.6	-3.6	-1.3
Eye problems/disorders: Cataract	2.7	3.2	8.1	-1.9	-1.6	-1.9	-1.1	-0.6	2.6	1.3	-2.2	-2.9	0.6	-2.5	-2.3	2.2	-0.7	0.5	-0.7	-1.4	-2.0
Age started oral contraceptive pill	2.7	3.4	16.5	1.1	1.4	1.1	2.4	-1.1	-1.9	-3.4	0.9	4.1	-1.4	2.1	1.1	-1.6	1.1	1.0	-0.9	1.9	0.8
Impedance of leg (left)	2.6	12.8	70.2	3.8	1.1	0.9	4.4	8.4	-0.8	3.1	2.0	-0.7	3.6	0.1	0.1	-1.0	-4.6	-4.7	5.5	-2.9	3.6
Medication: Simvastatin	2.5	3.7	13.5	2.1	-1.6	0.3	2.5	3.6	-1.1	1.1	-0.1	-0.7	-1.1	-1.4	-1.6	-1.2	-3.4	-3.7	0.4	-2.0	-0.3
Chronic bronchitis/emphysema (mother)	2.5	2.9	8.4	-0.5	-1.7	0.0	-1.0	0.7	-0.6	-0.9	-2.3	-2.0	-2.4	-1.3	-2.9	-0.7	-2.0	-1.5	-2.9	-1.3	-2.3
Medication: Cholesterol lowering	2.4	3.7	17.6	2.7	-0.9	0.7	2.4	4.2	-2.0	0.9	0.9	-0.4	-1.1	-0.5	-1.1	-2.2	-2.9	-3.4	0.5	-1.2	0.5
Peak expiratory flow (PEF)	2.4	5.7	22.3	-4.7	-0.0	-2.3	-2.3	-4.4	2.9	1.7	-0.3	0.5	1.2	-0.5	1.2	3.1	1.3	2.9	-0.9	3.3	-1.9
Headache pain in last month	2.4	4.2	14.3	3.8	1.0	2.7	2.0	2.5	-2.5	-1.8	0.0	-0.7	-2.8	1.3	0.6	-2.7	2.0	-2.5	-0.9	-1.9	0.8
Medication: Amlodipine	2.4	3.4	11.2	3.3	-0.4	1.2	1.5	3.3	-1.9	0.4	-0.3	-0.6	-2.3	-0.6	-2.2	-2.0	-1.4	-2.8	-0.3	-2.6	0.1
Cardiovascular Disease	2.3	7.6	29.7	4.4	1.3	2.8	3.6	5.4	-3.2	0.0	1.7	0.5	-0.8	1.0	0.8	-3.6	-2.7	-3.8	1.7	-2.4	2.5
Loud music exposure frequency	2.3	2.5	8.9	1.2	-1.5	-1.6	0.5	2.1	1.0	2.0	-0.1	-3.0	1.0	-1.8	-1.7	1.0	-2.0	-1.7	1.2	-2.0	-0.5
Commuting to job workplace: Public transport	2.3	2.7	7.5	1.7	-1.3	1.2	2.0	2.7	-1.0	0.1	-1.0	-1.2	-1.0	-0.9	-2.0	-1.4	-2.4	-2.6	-0.5	-2.7	-0.1
High cholesterol (Self-reported)	2.3	4.0	19.1	2.0	-0.7	1.2	2.5	4.4	-2.1	0.2	1.0	0.2	-0.2	0.2	-0.9	-2.2	-3.8	-3.4	1.2	-0.4	1.3
Bipolar Disorder (2011)	2.2	2.2	12.2	0.4	-0.8	0.2	-0.7	-2.7	-0.4	-2.3	-0.2	0.7	-1.7	0.3	0.9	0.1	3.5	2.4	-1.6	0.4	-0.3
Happiness	2.2	2.6	11.1	0.6	0.6	2.1	0.1	-0.2	-1.6	-2.6	-1.2	-0.9	-3.3	0.9	-0.7	-2.3	1.5	-1.2	-2.9	-0.6	-0.4
Health satisfaction	2.2	2.8	9.3	1.2	-0.8	0.0	-0.5	3.0	-0.2	0.2	-1.0	-2.9	-1.5	-1.4	-2.6	-0.8	-2.0	-2.0	-1.0	-3.0	-0.9
Medication for cholesterol	2.2	3.4	11.6	-2.2	-0.5	-2.4	-2.3	-3.4	2.7	1.0	0.6	-0.4	2.2	-0.3	1.3	2.6	1.8	2.4	1.0	0.8	-0.1
Type 2 Diabetes (T2D) (2012)	2.1	2.5	6.6	1.5	-1.6	-0.3	1.2	2.3	0.7	1.4	-1.3	-1.9	-1.3	-2.1	-2.1	0.4	0.1	-2.3	-0.4	-2.6	-1.6
Fasting Glucose	2.0	2.4	7.3	-0.1	-1.3	-2.7	0.6	0.2	1.8	2.1	1.8	-0.9	2.2	-1.7	-0.5	1.9	-0.3	0.4	2.3	-2.2	0.7
HbA1C	2.0	2.2	8.2	0.2	-0.9	-1.0	-0.6	2.0	1.6	2.9	-0.4	-2.3	0.5	-1.6	-0.9	1.8	-2.0	-2.1	0.4	-0.1	-1.5
Hand grip strength (right)	2.0	5.5	32.9	-2.2	-0.6	-0.4	-2.4	-5.7	1.5	-0.6	0.2	2.2	0.2	1.0	2.4	1.7	3.8	4.2	-0.6	2.3	0.0
Illnesses of siblings	2.0	2.8	7.8	-2.1	-1.2	-2.0	-2.2	-1.9	2.6	1.4	-1.1	-1.6	2.1	-1.2	-0.7	2.8	0.0	1.6	0.5	-1.2	-0.3
Heart disease (mother)	2.0	2.4	7.0	1.4	0.7	1.3	2.6	1.1	-2.2	-1.7	0.5	2.2	-2.6	0.4	-0.3	-2.2	-1.8	-1.1	-1.3	0.3	-0.3
Medication: Aspirin	2.0	2.6	7.4	1.9	1.4	1.7	1.5	1.3	-2.7	-1.4	2.1	1.6	-0.9	1.7	0.6	-2.7	-1.0	-1.7	0.2	0.9	1.6
Miserableness	2.0	3.4	12.8	3.6	0.7	1.8	1.5	2.7	-2.9	-2.4	0.7	-0.2	-1.8	1.1	0.1	-2.9	-0.2	-2.6	-0.3	-0.5	0.7
Vascular/heart problems diagnosed by doctor	2.0	5.5	17.6	-4.2	-0.4	-2.9	-2.2	-3.4	3.4	0.9	-0.0	0.4	3.1	-0.2	0.5	3.5	1.0	3.2	0.8	3.2	-0.6
Major Depression (MDD)	1.9	2.3	6.4	-2.1	-2.5	-1.8	-0.9	-1.5	2.4	0.9	-1.6	-0.7	0.4	-1.9	-1.0	2.1	0.5	1.2	-0.6	-1.3	-1.6
Schizophrenia (2014)	1.9	4.2	9.6	-2.5	-2.3	-2.7	-2.5	-2.2	2.0	0.1	-2.0	-1.2	-0.4	-2.4	-2.0	2.5	1.3	1.3	-1.9	1.7	-3.1
Hand grip strength (left)	1.9	5.1	29.1	-2.5	-0.6	-0.4	-3.0	-5.4	1.0	-1.2	-0.1	2.6	-0.2	1.3	1.6	1.2	2.1	3.7	-1.2	3.5	-0.2
Medication: Co-codamol	1.9	2.2	5.7	1.6	1.8	1.1	2.0	1.1	-1.6	-0.8	2.4	1.9	0.3	1.7	1.7	-1.7	0.0	-0.0	1.1	1.6	1.6
Pulse wave reflection index	1.9	2.3	8.9	-1.4	1.0	0.7	-0.7	-2.4	-0.3	-0.8	1.4	1.9	1.4	2.0	2.2	-0.2	-0.4	3.0	0.7	1.6	1.7
Leg pain on walking	1.9	2.4	8.3	2.2	0.5	1.2	2.4	2.9	-2.3	-0.7	0.7	-0.2	-1.3	0.1	-0.6	-2.2	-1.7	-2.0	-0.1	-1.6	0.4
Smoking Status	1.8	4.4	11.5	-3.4	-3.0	-2.5	0.0	-0.1	1.8	0.9	-2.3	-1.3	0.1	-2.5	-3.2	1.6	-3.4	-0.3	-1.7	0.7	-2.6
Heart attack	1.8	2.3	7.9	1.2	1.1	1.9	-0.6	-0.0	-2.8	-1.9	1.4	1.6	-0.5	2.3	1.4	-2.5	-0.3	0.4	0.0	1.2	1.9
Schizophrenia vs Biploar Disorder	1.7	2.2	7.3	-1.9	-0.8	-1.3	-1.2	-0.4	1.2	1.1	-2.4	-0.9	-0.4	-1.9	-2.7	1.3	-1.6	0.2	-1.3	1.1	-2.4
Heel T-Score	1.7	13.2	82.3	-5.4	-1.9	-0.5	-4.7	-9.1	-0.8	-2.8	-0.7	2.4	-1.6	1.5	-0.1	0.1	0.3	6.1	-4.7	4.1	-2.0
Other serious medical condition/disability diagnosed by doctor	1.7	2.2	6.9	-2.6	-1.3	-1.2	-0.8	-1.0	1.2	0.4	-2.2	0.2	-1.4	-1.6	-1.5	1.4	0.2	1.4	-1.8	1.0	-2.4
High blood pressure	1.7	4.8	14.9	3.9	0.7	2.5	2.0	3.1	-3.2	-1.1	0.2	-0.1	-2.8	0.2	-0.6	-3.4	-1.3	-2.8	-0.7	-2.9	0.7
Medication: Ramipril	1.7	2.2	6.2	2.5	0.6	2.2	0.7	1.3	-2.2	-0.2	-0.0	-1.5	-0.3	1.2	0.3	-2.5	-0.6	-2.5	0.2	-1.2	1.6
Falls in the last year	1.7	2.3	11.6	0.9	-0.6	0.5	0.1	2.9	0.4	1.1	-1.7	-2.8	0.4	-1.7	-1.2	-0.3	-0.5	-1.6	1.0	-3.4	0.1
Shortness of breath walking on level ground	1.7	2.1	8.8	1.9	-0.4	1.0	-0.2	3.0	-0.7	0.3	-0.8	-2.3	0.8	-0.2	-1.3	-1.3	-1.6	-1.5	1.0	-2.3	1.2
Hypertension (Self-reported)	1.7	4.6	13.3	3.6	1.0	2.4	2.0	3.4	-3.1	-0.8	0.1	-0.6	-2.5	0.0	-0.4	-3.3	-1.2	-2.9	-0.5	-3.0	0.6
Guilty feelings	1.7	2.6	6.6	0.6	-1.7	-0.6	0.9	2.5	0.4	-0.3	-1.8	-1.9	-1.0	-2.2	-2.6	-0.1	-2.4	-1.6	-1.1	-2.5	-1.3
Wears glasses or contact lenses	1.7	2.0	4.7	1.8	1.5	1.7	0.7	0.3	-2.2	-1.6	1.6	1.3	0.1	2.1	1.4	-2.1	-0.0	-0.4	0.9	0.6	2.0
Basal cell carcinoma (self-reported)	1.7	2.0	13.8	-0.1	0.3	1.6	-0.0	-2.0	0.1	-0.6	0.1	1.4	0.7	0.6	2.2	0.3	2.6	3.7	0.8	0.5	0.9
Angina (self-reported)	1.6	2.2	10.1	2.2	-0.2	1.0	2.1	3.2	-2.1	-0.6	0.5	0.7	-1.9	-0.1	-0.4	-1.9	-0.8	-1.9	-0.7	-0.8	-0.3
Mood swings	1.6	2.9	8.2	2.9	-0.0	1.1	2.1	2.3	-2.2	-1.9	0.1	0.6	-2.8	0.3	-1.0	-2.5	-0.6	-2.6	-0.9	-0.7	-0.1
Medication: Lisinopril	1.6	2.1	5.9	2.0	2.0	1.6	1.9	1.8	-2.0	-1.4	1.1	1.3	-1.5	1.0	0.7	-2.4	0.5	-1.1	-0.4	-0.1	0.4
Depression (Nagel 2018)	1.5	2.2	6.8	1.4	0.4	1.2	1.2	1.7	-2.3	-2.1	0.9	0.1	-1.3	1.4	-0.7	-2.6	-1.8	-2.4	-0.9	0.5	0.3
Schizophrenia (2018)	1.5	3.2	7.1	-2.1	-1.6	-2.5	-2.1	-1.3	2.1	1.0	-1.6	-1.1	0.3	-2.6	-2.2	2.4	0.2	1.5	-1.1	1.2	-2.7
Primary Biliary Cirrhosis	1.5	2.1	8.5	0.1	-0.8	-0.9	1.5	1.4	0.0	-0.3	-1.0	0.3	-2.9	-1.1	-1.6	0.1	-1.3	-2.2	-2.5	-0.2	-2.3
Medication: Atenolol	1.5	1.8	5.1	1.8	2.1	1.9	2.3	1.7	-1.7	-0.8	-0.1	1.5	-1.3	0.7	1.1	-1.6	0.5	-0.5	0.2	-0.7	0.9
Number of incorrect matches in round	1.5	2.5	5.7	-1.2	-1.2	-1.4	-1.4	-1.3	2.2	1.6	-2.2	-1.8	1.7	-2.4	-0.8	2.0	0.6	1.7	1.0	-1.9	-0.8
Exposure to tobacco smoke at home	1.5	1.7	5.8	1.1	-0.9	0.2	0.5	1.9	-1.1	-1.0	-0.6	-2.1	-0.6	-0.3	-2.4	-1.2	-2.2	-1.2	-0.6	-2.0	0.0
Number of children fathered	1.5	1.7	5.7	-1.3	-0.6	-1.5	-2.2	-1.0	1.6	1.7	-0.4	-2.4	0.9	-1.0	-0.4	1.6	1.0	1.4	-0.3	-0.1	-1.3
Medication for pain relief, constipation, heartburn	1.5	2.5	5.8	-2.3	-0.1	-1.5	-2.3	-2.4	2.2	1.1	-0.8	0.2	2.0	-0.6	1.0	2.3	0.0	2.3	0.4	1.7	-0.8
Number of full sisters	1.5	1.9	6.9	2.5	-0.6	0.6	-0.9	-0.3	-2.3	-2.6	0.6	1.4	-1.2	1.4	-1.0	-2.3	-0.5	-0.0	-0.5	-0.1	1.4
Suffer from ‘nerves’	1.5	2.4	9.3	1.8	-0.7	-0.3	0.3	2.8	-0.4	-0.2	-1.4	-1.7	-1.5	-0.9	-2.7	-0.7	-1.8	-3.0	-0.8	-1.3	-0.8
Chest pain or discomfort	1.5	2.1	8.8	2.3	0.2	0.9	1.8	3.0	-1.2	0.0	0.3	-0.8	-1.7	-0.6	-1.0	-1.3	0.2	-2.2	-0.3	-2.6	0.0
Heart attack/myocardial infarction (self-reported)	1.5	1.9	5.0	0.7	0.9	1.5	-0.9	-0.5	-2.2	-1.5	1.5	1.7	-0.3	2.2	1.7	-1.9	-0.1	0.8	0.1	1.5	1.7
Systolic Blood Pressure	1.4	7.0	27.6	5.2	0.6	2.0	3.9	4.9	-2.8	0.4	1.4	1.7	-1.2	0.2	0.4	-2.8	-2.7	-3.1	1.9	-2.9	1.9
Number of treatments/medications taken	1.4	2.5	7.1	1.0	0.3	1.9	2.3	2.0	-2.2	-1.4	-0.9	-0.1	-2.7	-0.1	-1.4	-2.6	-0.5	-1.4	-1.8	-1.6	-0.3
Angina	1.4	1.9	9.0	2.1	-0.4	0.8	2.2	3.0	-1.9	-0.5	0.5	0.6	-1.7	-0.3	-0.4	-1.6	-0.7	-1.7	-0.5	-1.0	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	1.4	1.9	6.6	0.6	-0.3	0.3	0.1	2.0	-1.5	-1.2	-0.3	-1.1	-1.5	0.3	-2.1	-1.9	-2.2	-2.6	-1.6	-0.2	-0.7
Age at first live birth	1.4	2.4	9.9	1.9	2.3	0.7	-0.1	0.2	-0.8	-0.7	3.1	1.5	0.4	1.8	2.2	-0.8	2.2	0.3	1.2	2.0	1.2
Emphysema/chronic bronchitis	1.4	1.6	5.4	0.9	-1.8	-0.7	0.6	1.5	0.4	0.8	-0.5	-1.1	-1.1	-1.7	-2.2	0.1	-1.2	-0.9	-0.9	-2.3	-1.1
Ever had bowel cancer screening	1.4	1.6	5.1	0.5	-1.6	-0.2	1.5	0.8	-0.4	-0.7	-1.4	-0.3	-2.3	-1.8	-1.2	-0.1	0.2	-0.4	-1.7	-2.2	-1.8
Osteoarthritis (self-reported)	1.4	1.8	4.5	1.0	0.4	0.1	1.0	0.6	-2.1	-2.1	1.5	1.5	-1.1	1.2	-0.6	-2.1	-2.0	-1.6	-0.3	1.5	0.8
Number of self-reported non-cancer illnesses	1.4	2.5	9.3	2.3	0.2	1.2	2.1	3.0	-2.2	-0.7	-0.2	-0.4	-1.3	0.3	-1.2	-2.3	-1.3	-2.5	-0.0	-1.4	0.6
Heart disease (siblings)	1.4	1.7	4.7	1.8	1.3	1.7	1.9	1.4	-2.1	-1.2	0.9	1.1	-0.9	1.1	0.9	-2.2	0.1	-0.4	0.6	0.4	1.1
Alzheimer’s Disease (in father)	1.3	1.4	5.1	-0.1	0.6	1.3	-0.9	-1.0	-0.9	-1.6	0.5	1.5	-0.3	1.2	1.9	-0.4	2.3	1.4	-0.2	1.6	0.2
Type 2 Diabetes (T2D) (2018)	1.3	2.5	7.1	-0.4	-0.5	-1.4	0.7	2.4	1.6	2.7	-0.3	-2.3	0.6	-2.2	-2.0	1.4	-2.0	-1.7	0.3	-0.9	-1.6
Lung FVC	1.3	6.8	24.4	-4.6	-1.0	-1.5	-1.5	-4.9	1.2	-1.7	-1.0	3.5	-1.5	0.1	-0.3	1.7	1.3	3.3	-3.3	4.2	-2.9
Neuroticism	1.3	3.2	10.5	2.4	-1.6	-0.3	0.7	3.2	-0.7	-0.1	-0.3	-2.5	-0.4	-1.5	-1.9	-1.1	-2.7	-2.8	0.7	-2.8	0.2
Chronotype (morning person)	1.3	3.0	7.6	1.6	2.6	1.3	1.5	0.9	-1.8	-0.5	2.2	2.5	0.5	2.1	2.8	-1.4	-0.4	-0.4	1.7	1.7	2.0
Medication: Metformin	1.3	1.8	5.0	-0.3	-1.2	-1.1	-0.5	1.4	1.0	1.8	-0.9	-2.2	-0.0	-1.6	-1.9	0.7	-2.0	-2.2	-0.4	0.2	-1.4
Townsend deprivation index at recruitment	1.3	1.8	8.1	0.2	-1.6	-0.7	1.3	1.8	0.5	1.1	-1.8	0.1	-0.6	-1.9	-2.8	0.4	-1.9	-1.5	-0.3	-0.6	-1.2
Average weekly fortified wine intake	1.3	1.6	4.5	0.7	0.8	1.9	0.9	-1.2	-2.0	-2.0	-0.9	1.4	-1.2	1.2	0.7	-2.1	0.5	0.6	-0.8	0.3	0.9
Taking other prescription medications	1.3	2.1	6.8	0.8	0.8	1.1	1.1	1.4	-2.5	-2.1	-0.1	0.5	-2.1	1.1	-1.5	-2.6	-1.4	-1.4	-1.6	0.3	0.1
Body mass index (BMI)	1.3	5.5	22.5	-2.5	-2.3	-1.6	-2.9	-2.0	0.7	-0.8	-2.1	-1.3	-3.4	-1.8	-2.8	0.5	-1.2	-0.3	-4.7	0.1	-4.2
Alcohol usually taken with meals	1.3	2.1	7.6	-1.5	0.0	-1.6	-2.7	-2.0	2.2	1.4	0.7	-1.6	1.6	-0.6	1.4	1.9	1.0	0.7	0.5	0.5	-0.7
Pulse wave peak to peak time	1.3	1.5	4.2	0.6	0.1	-0.6	0.5	1.8	1.6	1.9	-0.7	-1.7	-0.3	-1.7	-0.1	1.3	0.8	-2.0	-0.1	-1.2	-1.6
Neck or shoulder pain in last month	1.3	1.8	6.3	1.0	0.2	2.5	0.5	2.3	-1.4	-0.5	-1.8	-1.5	-0.4	0.4	-0.6	-1.9	-2.3	-1.5	-0.0	0.1	0.6
Migraine (self-reported)	1.3	1.6	8.2	1.2	1.8	-0.1	1.5	2.9	-0.0	1.3	0.9	-1.0	0.1	0.2	-0.1	-0.4	0.8	-2.3	0.6	-1.8	0.2
Friendships satisfaction	1.3	1.6	4.8	1.7	1.7	2.2	0.7	0.6	-1.8	-1.1	0.4	0.3	-0.6	1.6	0.6	-2.0	0.8	-1.1	0.2	-0.5	1.8
Qualifications: nursing, teaching	1.3	2.0	8.2	1.3	2.0	1.0	0.9	0.2	0.1	0.5	1.4	0.3	0.9	1.3	2.9	0.4	2.9	1.0	1.6	1.5	0.9
Breast cancer (self-reported)	1.3	1.6	5.7	0.2	0.7	1.6	0.1	-0.5	-1.7	-2.4	-0.4	1.9	-1.2	1.8	0.3	-1.9	-0.2	0.3	-1.3	1.3	0.6
Smoking status: Current	1.3	2.0	5.1	-2.1	-2.2	-1.5	-1.3	0.2	1.7	0.5	-1.8	-1.4	0.5	-1.9	-2.1	1.0	-1.6	0.5	-0.9	-0.5	-1.5
Tinnitus: Yes, now most or all of the time	1.3	1.6	8.9	-1.0	-1.3	-0.6	-2.6	-3.0	0.5	-1.2	-0.5	-0.2	0.1	0.4	-0.2	0.5	1.4	1.7	-0.9	0.8	-0.6
Cholesterol lowering medication	1.3	2.0	7.9	1.2	-0.9	1.6	1.8	2.8	-1.3	-0.0	-1.0	-0.3	-0.6	-0.4	-1.1	-1.4	-2.6	-2.1	0.3	-1.4	0.5
Bipolar Disorder or Schizophrenia	1.2	2.9	8.7	-1.1	-2.9	-2.0	-1.5	-1.3	1.5	0.1	-1.8	-1.5	-0.4	-2.6	-2.3	1.9	1.2	1.2	-1.4	-0.3	-2.4
Lupus	1.2	1.8	6.7	-0.7	2.6	1.3	-1.4	-1.2	-0.6	-0.7	0.0	1.1	1.0	1.5	2.1	-0.5	-0.1	2.1	0.9	1.4	1.5
Rheumatoid Arthritis	1.2	1.7	9.3	0.0	0.9	-1.1	-3.0	-1.0	1.4	1.2	-0.4	-1.6	2.2	0.0	0.7	1.6	-0.4	0.7	1.5	1.1	0.0
Vitamin and mineral supplements	1.2	1.6	6.1	-0.1	-0.3	-0.1	-0.2	0.4	-0.1	-0.1	-1.9	-1.7	-1.8	-0.7	-1.3	-0.6	-2.5	-2.0	-1.9	-0.6	-1.6
Current tobacco smoking	1.2	2.0	5.2	-2.1	-2.3	-1.6	-0.8	0.2	1.5	0.5	-1.5	-1.4	0.2	-1.9	-2.2	0.9	-1.8	0.2	-1.0	-0.6	-1.5
Heel bone mineral density (BMD) T-score, automated (left)	1.2	2.6	13.0	-2.7	0.8	-0.9	-2.6	-3.6	0.0	0.5	1.0	0.7	0.6	1.1	0.5	0.9	0.8	2.3	-1.0	2.8	-0.4
Alcohol intake versus 10 years previously	1.2	1.9	6.1	1.1	2.0	1.5	2.4	1.6	-1.4	0.2	1.3	2.5	-0.4	1.4	-0.3	-1.2	0.2	-1.5	0.5	0.1	1.3
Length of working week for main job	1.2	1.4	5.2	2.1	-1.2	-0.4	0.5	2.3	-0.1	1.0	0.7	-1.3	0.2	-1.3	-0.9	-0.3	-1.1	-0.9	1.2	-1.9	0.3
High blood pressure (siblings)	1.2	1.7	3.3	1.7	1.1	1.5	1.0	1.5	-1.8	-1.1	1.3	1.4	-1.8	1.4	0.9	-1.8	0.8	-1.7	-0.6	1.1	0.1
Comparative body size at age 10	1.2	3.4	13.8	-3.0	-1.1	-1.6	-2.9	-3.7	0.1	-2.1	-0.8	0.6	-1.3	0.1	-1.5	0.6	-0.9	2.1	-3.0	1.4	-1.3
Diabetes diagnosed by doctor	1.2	2.0	5.8	-0.2	-0.9	-0.9	0.3	2.1	1.0	2.1	-0.9	-2.0	0.3	-1.9	-2.4	0.7	-2.0	-1.8	-0.2	-0.6	-1.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.4	5.4	0.8	-1.8	-0.0	-0.2	1.4	-0.3	1.1	-0.6	-1.5	-0.0	-0.9	-2.3	-0.4	-1.9	-1.1	-0.1	-1.9	-0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.5	8.5	-2.5	1.1	0.1	0.1	-2.2	-0.5	-1.7	0.4	2.9	-1.6	1.1	0.9	-0.1	1.0	1.5	-2.1	2.7	-0.9
Pain type(s) experienced in last month: Hip pain	1.2	1.5	4.5	-1.4	-1.7	-0.8	-1.3	-0.6	-0.5	-1.1	-0.8	-0.1	-1.4	-0.6	-2.1	-0.5	-1.2	-0.2	-2.1	0.9	-1.7
Supplements: Fish oil (including cod liver oil)	1.2	1.5	5.8	-1.8	0.5	-0.7	-1.1	-2.2	0.5	-0.3	0.1	0.4	1.3	-0.2	0.8	1.1	2.2	2.4	0.4	1.4	-0.1
Commuting to job workplace: Cycle	1.2	1.4	5.2	2.3	-0.4	1.7	0.5	-0.5	-1.4	-1.1	0.3	1.4	-0.2	1.1	1.2	-1.7	0.7	1.1	1.1	0.3	1.7
Pain experienced in last month	1.2	1.9	9.6	-1.9	-0.8	-1.1	-1.5	-3.1	1.5	0.4	0.3	1.1	-0.1	-0.2	0.9	1.7	0.8	2.6	-0.8	1.2	-0.9
Depressed Affect (Nagel 2018)	1.1	2.4	11.6	2.5	0.3	0.5	1.6	2.4	-1.9	-1.4	0.8	-0.9	-1.7	0.1	-0.7	-2.0	-1.0	-3.4	-0.2	-0.8	0.2
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	3.0	-0.4	0.8	1.2	1.1	0.2	-1.6	-1.7	-0.4	1.1	-1.5	0.8	0.6	-1.5	-0.4	0.2	-1.3	1.7	-0.2
Sitting height	1.1	7.7	21.2	4.5	3.9	2.0	3.0	2.0	0.3	3.1	2.2	0.2	1.6	0.3	4.6	0.0	4.0	-0.2	4.3	-2.4	2.9
Had other major operations	1.1	1.4	5.8	-0.4	1.0	1.3	0.8	-0.7	-1.3	-2.4	-1.2	1.7	-1.1	1.4	-0.6	-0.9	-0.1	0.4	-1.5	1.4	0.1
Diabetes (self-reported)	1.1	1.7	5.5	0.3	-0.5	-0.6	0.4	2.3	0.6	1.4	-1.0	-2.1	0.3	-1.7	-2.0	0.3	-1.8	-2.1	0.2	-0.5	-1.1
Glaucoma (self-reported)	1.1	1.3	5.2	0.5	-0.9	-0.9	-0.0	1.7	0.6	0.8	-0.1	-2.3	-0.2	-1.2	-1.4	0.6	-0.5	-2.2	0.2	-1.3	-0.8
Wheeze or whistling in the chest in last year	1.1	1.9	8.7	1.1	-0.2	-0.4	0.7	2.7	0.4	0.3	-0.3	-2.9	0.6	-1.1	-1.3	-0.1	-0.9	-1.5	1.0	-3.0	0.9
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	4.1	-0.4	-0.2	-0.7	-1.0	-1.6	1.4	1.2	0.5	-0.0	2.0	-0.1	0.3	1.0	1.2	1.8	1.5	0.6	0.5
Mother’s age at death	1.1	1.4	5.7	1.3	1.5	1.0	-0.0	-0.4	-1.1	-0.8	2.4	1.1	0.3	2.2	1.0	-1.1	-0.3	-0.2	0.7	0.6	1.8
Medication: Bendroflumethiazide	1.1	1.7	4.5	1.0	0.9	1.6	1.8	0.3	-1.9	-2.1	-0.1	1.0	-2.1	1.2	-0.1	-2.0	0.4	-0.6	-1.4	0.4	0.5
Illnesses of father: High blood pressure	1.1	1.4	6.4	2.1	0.9	-0.0	2.5	1.7	-0.8	0.0	0.8	-0.1	-0.8	-0.3	-0.5	-0.6	-0.1	-2.2	0.3	-1.8	0.3
Leg fat percentage (left)	1.1	4.0	11.2	-0.7	-1.9	-1.1	-1.2	1.8	-0.1	0.2	-1.1	-1.9	-2.6	-1.8	-3.1	-0.6	-3.4	-2.7	-2.9	-1.3	-2.9
Neuroticism (Nagel 2018)	1.0	2.4	8.8	2.8	-0.3	0.0	1.4	3.0	-1.2	-0.8	0.7	-1.5	-0.3	-0.5	-1.0	-1.4	-1.6	-2.9	1.0	-2.0	0.8
Age at First Birth	1.0	1.5	7.0	0.1	-0.7	-0.2	-0.7	-1.2	1.0	0.7	-0.0	1.3	2.7	0.4	0.4	0.9	0.3	1.9	2.3	1.7	1.2
Neuroticism (2016)	1.0	1.4	4.3	0.7	-1.0	-1.3	0.1	1.6	0.9	0.2	-0.8	-1.5	-1.3	-1.7	-1.6	0.8	0.4	-1.0	-1.0	-1.3	-2.1
Medication for hormone replacement therapy	1.0	1.1	3.4	0.8	0.0	0.4	1.2	1.4	-1.0	-0.4	0.6	1.4	-1.5	0.6	-1.2	-1.0	-1.9	-1.2	-1.0	0.3	-0.6
Trunk fat percentage	1.0	3.9	15.5	1.0	-0.5	-0.4	1.3	3.9	-0.3	0.9	-0.3	-1.4	-2.0	-2.0	-2.4	-0.7	-3.1	-3.5	-1.3	-2.9	-1.8
Maternal smoking around birth	1.0	1.5	4.0	0.2	-0.1	1.3	0.4	1.9	-1.9	-1.7	-0.4	0.3	-0.9	0.8	-0.8	-2.0	-2.0	-1.8	-0.4	-0.2	0.9
Fed-up feelings	1.0	1.9	8.6	1.5	-0.7	-0.2	0.4	2.2	-0.4	-0.9	-0.1	-1.0	-2.4	-0.5	-1.5	-0.9	-1.0	-2.9	-1.7	-0.2	-1.5
Chronic bronchitis/emphysema (father)	1.0	1.2	4.8	-0.8	-0.1	0.5	-1.2	-1.4	-1.1	-2.2	0.8	0.5	0.0	2.0	0.5	-1.3	0.5	0.8	-0.7	1.2	0.9
Nervous feelings	1.0	1.8	6.2	2.0	-1.3	-0.0	0.9	1.3	-0.5	-0.8	-1.8	-1.7	-1.3	-1.4	-1.7	-0.5	0.2	-1.8	-0.3	-2.5	-0.7
Frequency of tenseness / restlessness in last 2 weeks	1.0	1.6	8.9	1.2	-0.8	-0.1	-0.1	1.6	-0.5	-0.4	-0.3	-2.0	-1.2	-0.1	-1.9	-0.9	-1.5	-3.0	-1.1	-1.1	-0.5
Hearing difficulty/problems with background noise	1.0	1.6	6.8	0.4	1.1	1.2	1.2	-0.7	-1.7	-2.6	-0.8	1.1	-1.8	0.6	0.2	-1.4	2.2	1.0	-1.1	0.1	0.2
Qualifications: None of the above	1.0	2.1	8.8	-0.9	-2.5	-1.8	-0.1	0.9	0.1	-0.1	-0.7	0.1	-1.0	-1.6	-2.9	-0.1	-3.0	-0.6	-1.0	-1.7	-0.9
Neuroticism score	1.0	2.1	6.7	2.4	-1.1	0.2	0.9	2.3	-1.1	-1.0	-0.9	-1.7	-1.6	-0.9	-1.5	-1.4	-0.8	-2.6	-0.5	-2.0	-0.3
Worrier / anxious feelings	1.0	1.9	6.7	2.1	-0.9	0.2	0.8	1.4	-1.4	-2.2	-0.6	-0.6	-1.6	-0.8	-2.2	-1.6	-0.7	-0.7	-0.6	-2.6	0.2
Number of live births	1.0	1.4	8.9	-0.4	0.3	1.3	-1.9	-3.0	-0.5	-0.9	-0.0	-0.3	0.4	1.8	1.0	-0.6	0.4	1.1	0.1	0.3	1.7
Prospective memory result	1.0	1.2	6.5	-1.0	-2.5	-1.1	0.1	-0.2	0.7	0.3	-0.8	0.7	-0.9	-1.4	-1.4	0.9	-0.3	1.0	-1.3	-0.6	-1.8
Breastfed as a baby	1.0	1.2	4.9	-1.3	1.0	1.1	-0.2	-1.0	-1.4	-1.5	-0.1	0.8	-0.7	1.0	1.2	-1.3	-0.8	0.5	-1.2	2.2	-0.2
Leg fat percentage (right)	1.0	3.7	12.2	0.3	-1.5	-0.7	-0.3	2.7	-0.4	0.3	-0.5	-1.9	-2.4	-1.4	-2.7	-1.0	-3.5	-3.4	-2.3	-1.8	-2.2
Arm fat-free mass (right)	1.0	5.1	14.4	-1.8	-1.1	-1.5	-3.8	-3.4	2.5	1.6	-1.8	-1.9	-2.0	-2.0	-0.2	2.0	2.4	0.8	-2.9	1.4	-3.7
Worry too long after embarrassment	1.0	1.7	8.3	1.9	-0.8	0.5	1.8	2.9	-1.2	-0.7	0.7	-0.1	-0.7	-0.6	-0.4	-1.1	-1.0	-1.3	0.4	-2.6	0.9
Mouth/teeth dental problems: Loose teeth	1.0	1.1	4.0	-1.2	-1.2	-0.4	-1.2	-0.0	0.8	0.8	-0.5	-0.7	-1.0	-1.0	-2.0	0.3	-1.5	0.2	-1.8	-0.2	-1.6
Medication: Blood pressure	1.0	1.9	6.2	1.3	0.6	2.2	1.1	1.3	-2.2	-1.4	-0.2	-0.1	-2.5	0.2	-0.4	-2.3	0.1	-1.3	-1.6	-1.4	-0.1
Ever smoked	1.0	1.7	5.6	-1.2	-1.5	-1.8	0.3	0.4	1.8	2.1	-0.5	-1.2	2.4	-1.6	-1.0	1.8	-0.7	0.2	1.2	0.0	-0.5
Worry (Nagel 2018)	0.9	1.9	5.4	2.3	-0.6	0.1	0.9	2.3	-1.2	-1.3	-0.4	-1.5	-1.0	-0.4	-1.5	-1.5	-1.5	-2.3	0.1	-1.8	0.5
Mean Putamen Volume	0.9	1.1	3.2	-0.1	-0.7	-1.4	-0.5	0.1	1.7	1.5	-0.5	-0.5	0.6	-1.8	-0.5	1.7	1.2	0.8	0.4	-1.1	-0.8
HDL Cholesterol	0.9	1.5	5.0	-0.7	-0.8	-1.0	-0.6	0.6	1.6	1.2	-1.9	-1.8	-0.8	-2.0	-0.7	1.3	-0.1	-0.0	-1.0	-0.6	-2.2
Qualifications: CSEs or equivalent	0.9	1.2	4.0	-0.2	-0.9	-1.3	1.1	2.0	1.3	1.5	0.2	0.2	0.4	-1.1	-1.4	1.5	-0.6	-1.6	0.5	-0.6	-0.9
Waist circumference	0.9	3.1	9.7	-1.1	-1.2	-1.7	-2.0	0.6	1.2	1.0	-1.0	-2.6	-1.6	-2.1	-2.2	0.7	-1.8	-2.1	-2.3	-0.7	-3.1
Past tobacco smoking	0.9	1.7	3.7	0.3	1.2	1.4	-1.1	-1.3	-1.3	-1.6	1.3	1.5	-1.9	1.9	1.4	-1.2	1.6	0.5	-1.4	0.9	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.1	8.5	-2.1	1.2	-0.2	-2.2	-2.9	-0.9	-0.2	1.4	1.4	0.3	1.4	0.6	-0.1	-0.0	2.0	-0.8	2.7	0.2
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	7.1	-0.1	2.7	0.7	-0.2	-0.5	-1.2	-0.7	0.4	-0.2	0.6	1.6	1.7	-1.1	0.9	-0.3	0.3	1.2	1.1
Pulse wave Arterial Stiffness index	0.9	1.0	3.0	-0.2	0.1	0.7	-0.2	-1.2	-1.5	-1.4	0.6	1.2	0.5	1.4	0.2	-1.2	-0.7	1.6	0.5	0.8	1.7
Mouth/teeth dental problems: Bleeding gums	0.9	1.2	4.2	1.3	1.2	1.3	0.2	2.0	-0.3	0.5	0.2	-0.7	0.8	0.6	0.8	-0.7	-0.5	-0.3	1.4	-1.9	1.6
Body fat percentage	0.9	3.7	10.9	0.3	-1.0	-0.7	0.5	3.1	-0.2	0.5	-0.5	-1.5	-2.2	-1.9	-2.7	-0.7	-3.3	-3.2	-2.0	-2.4	-2.2
Exposure to tobacco smoke outside home	0.9	1.2	6.2	0.3	-1.5	-0.6	1.0	1.3	-0.3	-1.0	-0.7	-0.2	-1.8	-0.5	-2.5	-0.2	-0.8	-0.6	-1.6	-0.6	-1.2
Average weekly red wine intake	0.9	1.4	6.6	-0.2	0.5	-0.6	-2.6	-1.4	0.7	1.0	-0.3	-0.9	2.0	0.1	1.1	0.6	-0.4	0.5	0.9	2.5	-0.0
Loneliness, isolation	0.9	1.2	9.2	-0.2	-0.8	-0.2	-0.6	1.0	0.0	0.9	-0.4	-3.0	-0.5	-0.9	-1.0	-0.5	-1.1	-2.4	-0.4	-0.2	-0.5
Mineral and other dietary supplements	0.9	1.2	6.0	1.4	-0.1	1.1	0.1	1.7	-0.7	0.1	-0.8	-0.6	-0.9	0.5	-0.5	-1.2	-2.4	-1.8	-0.4	-1.1	0.4
Ever taken oral contraceptive pill	0.9	1.0	3.3	-0.5	0.5	0.6	1.0	-0.6	-0.7	-0.5	1.8	1.4	0.5	1.5	1.2	-0.6	0.6	1.1	0.4	-0.5	1.7
Ever depressed for a whole week	0.9	1.1	3.8	-0.4	-0.7	-0.7	-1.2	0.5	1.2	0.6	-1.2	-1.9	-1.1	-1.5	-0.5	1.0	1.0	-0.9	-1.0	-1.0	-1.5
Unable to work because of sickness or disability	0.9	1.1	4.0	-1.4	-1.5	-0.9	-1.0	0.4	-0.2	-0.4	-0.1	-1.9	-0.5	-0.4	-2.0	-0.1	-1.0	-1.2	-1.4	0.2	-1.1
Myopia	0.9	1.3	4.6	1.0	-0.7	0.5	1.4	2.1	-0.6	0.2	-0.6	-0.3	-1.8	-0.7	-1.4	-0.8	-1.1	-2.1	-1.0	-1.0	-1.1
Leg fat mass (left)	0.9	3.5	10.4	-0.8	-1.2	-1.4	-1.4	1.1	0.4	0.7	-1.0	-2.1	-2.6	-2.0	-2.5	-0.0	-2.4	-2.5	-3.0	-0.9	-3.2
Bipolar Disorder (2018)	0.8	1.2	8.0	0.8	-2.8	-0.0	0.1	-0.5	-0.1	-0.9	-1.0	-1.1	-0.9	-0.9	-1.0	0.1	1.6	0.1	-0.8	-2.0	-0.5
Ulcerative Colitis	0.8	1.1	5.7	1.0	1.0	0.4	1.4	-0.4	-1.5	-0.5	0.4	2.4	-0.3	1.1	0.7	-1.1	-0.7	0.7	0.1	1.8	0.7
Blood Platelet Count	0.8	9.0	43.7	4.1	3.5	1.5	6.0	6.6	-2.8	0.6	2.2	4.0	-1.5	0.8	0.7	-1.8	-1.4	-3.3	1.3	1.2	0.3
Average weekly spirits intake	0.8	1.0	4.3	0.0	-2.1	-1.1	1.6	1.3	-0.5	0.5	-0.0	0.6	0.3	-1.3	-1.2	0.5	-1.1	-0.5	0.9	-1.1	-0.4
Frequency of depressed mood in last 2 weeks	0.8	1.1	3.3	0.7	-0.4	0.9	0.9	1.4	-1.2	-1.3	-0.0	-0.3	-1.0	0.6	-1.2	-1.6	-1.5	-1.8	-0.8	0.2	-0.2
Multivitamins +/- minerals	0.8	1.0	5.6	-0.1	0.5	0.4	0.2	-0.7	-0.5	-0.8	1.2	1.8	0.6	1.0	0.9	0.1	2.4	1.1	0.5	1.3	0.9
Trunk fat mass	0.8	3.2	10.0	0.7	-0.5	-0.6	0.2	2.8	0.0	0.9	-0.5	-2.0	-2.5	-2.1	-2.1	-0.5	-2.0	-3.2	-2.0	-2.3	-2.4
Mouth/teeth dental problems	0.8	1.2	5.6	0.2	0.7	0.2	0.8	-0.7	-0.2	-0.3	1.4	1.9	-1.1	1.0	1.8	-0.2	1.4	-0.6	-0.5	2.4	-0.4
Arm fat percentage (right)	0.8	3.2	8.7	-0.3	-1.1	-0.7	0.2	1.8	-0.7	-0.7	-0.9	-1.3	-2.8	-1.6	-2.7	-0.9	-2.6	-2.3	-2.9	-1.9	-2.5
Lung cancer (father)	0.8	0.9	3.9	1.5	0.3	1.3	2.0	1.0	-1.3	-0.9	-0.1	0.4	-0.8	0.6	0.3	-1.2	0.2	-0.8	0.1	-1.1	0.8
Birth weight of first child	0.8	1.5	4.3	1.4	-0.9	-0.0	-0.6	2.1	0.9	1.8	-0.9	-1.7	-0.2	-1.7	-0.9	0.3	-1.0	-1.5	-0.1	-1.9	-1.0
Medication: Allopurinol	0.8	1.0	4.1	-0.4	0.7	-0.2	1.6	-0.5	-2.0	-1.4	1.2	0.9	-2.0	0.2	-0.1	-1.2	0.2	-0.3	-1.1	0.2	-0.1
Leg fat mass (right)	0.8	3.2	8.0	-0.2	-1.1	-1.0	-0.8	1.6	0.1	0.6	-0.6	-2.0	-2.6	-1.7	-2.4	-0.4	-2.4	-2.8	-2.7	-1.2	-2.8
Arm predicted mass (right)	0.8	4.3	13.1	-1.4	-1.0	-1.2	-3.6	-3.0	2.2	1.4	-1.7	-1.8	-2.2	-1.8	-0.3	1.6	2.2	0.4	-3.0	1.3	-3.6
Commuting to job workplace: Car/motor vehicle	0.8	0.9	4.8	-0.8	1.0	-0.5	-1.2	-2.2	-0.3	-0.8	0.8	0.4	0.1	1.2	1.0	-0.0	1.6	1.4	-0.5	0.4	0.3
Leg fat-free mass (right)	0.8	4.2	13.1	-1.6	0.1	-0.9	-3.0	-3.6	1.4	-0.1	-1.3	-0.9	-2.7	-1.1	0.2	1.1	3.1	1.1	-3.4	1.6	-3.3
Arm fat percentage (left)	0.8	3.3	10.9	-0.7	-1.2	-0.8	-0.2	1.4	-0.4	-0.7	-1.2	-1.4	-3.0	-1.7	-2.7	-0.6	-2.1	-2.2	-3.3	-1.7	-2.8
Long-standing illness, disability or infirmity	0.8	1.2	5.4	-0.3	-0.4	0.6	0.9	1.3	-0.8	-0.4	-1.9	-0.6	-1.2	-0.9	-2.3	-1.1	-1.2	-0.9	-1.1	-0.3	-1.1
Leg predicted mass (right)	0.8	4.2	12.9	-1.6	0.2	-0.9	-3.1	-3.6	1.4	-0.1	-1.3	-0.9	-2.6	-1.1	0.2	1.1	3.1	1.1	-3.4	1.6	-3.2
Arm fat mass (left)	0.8	3.2	12.0	-0.8	-1.2	-0.9	-0.9	0.6	0.3	-0.1	-1.5	-1.7	-3.1	-2.0	-2.2	-0.0	-1.1	-1.9	-3.5	-1.2	-3.4
Eye problems/disorders: Glaucoma	0.8	0.9	4.2	0.8	-0.1	-0.6	-0.4	1.5	-0.1	0.1	0.7	-1.9	-0.2	-0.4	-1.2	-0.4	-1.1	-2.1	0.2	-1.2	-0.0
Medication: Atorvastatin	0.8	1.0	3.2	0.7	1.3	1.8	0.3	1.5	-1.0	-0.3	0.0	0.2	0.7	1.1	0.7	-1.4	-0.4	-0.5	0.8	1.1	1.4
Arm fat-free mass (left)	0.8	4.0	13.0	-1.2	-1.0	-1.4	-3.2	-2.5	2.2	1.8	-1.5	-2.0	-1.8	-2.0	-0.3	1.8	2.2	0.3	-2.6	0.9	-3.6
Risk taking	0.8	1.2	5.0	-1.0	0.6	-0.1	-0.9	-1.8	0.4	0.3	1.6	0.5	0.6	1.0	1.7	0.4	0.7	1.6	-0.1	2.2	0.2
BMI	0.7	3.8	17.7	-1.6	-1.8	-1.6	-1.9	-2.1	-0.2	-1.6	-0.7	-1.1	-3.2	-1.2	-2.5	-0.3	-1.3	-0.4	-4.2	-0.4	-3.0
Supplements: Zinc	0.7	0.7	3.8	0.8	0.9	1.2	1.3	-0.1	-0.7	-0.6	0.4	1.0	-0.9	0.7	0.6	-0.9	1.9	0.2	-0.4	0.2	0.3
Diabetes (mother)	0.7	0.9	4.9	0.3	-0.2	1.2	0.4	0.9	-0.9	0.4	-1.5	0.3	-0.1	-0.5	-1.3	-1.1	-2.2	-1.2	0.2	-0.9	0.2
Age when periods started (menarche)	0.7	1.7	10.0	1.7	-0.7	0.1	1.7	2.1	0.3	2.0	-0.6	-0.4	-0.1	-1.3	-0.5	0.2	0.5	-1.4	0.9	-3.2	0.2
Father’s age at death	0.7	1.0	2.6	-0.8	1.3	0.6	-0.7	-1.6	0.0	-0.6	0.7	0.7	0.6	1.5	1.4	0.1	1.2	1.2	0.2	1.3	1.1
Forced expiratory volume in 1-second (FEV1)	0.7	2.2	10.2	-2.2	0.9	-1.0	-0.7	-2.5	1.2	0.7	-0.1	1.6	-0.2	0.1	1.6	1.4	1.3	1.3	-0.9	3.2	-1.6
Arm fat mass (right)	0.7	3.1	10.5	-0.7	-1.2	-1.0	-0.9	0.8	0.2	-0.0	-1.3	-1.7	-2.8	-2.0	-2.4	-0.1	-1.7	-1.9	-3.2	-1.3	-3.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	5.2	-0.8	-1.1	-1.1	0.2	0.8	0.1	-0.5	-1.6	-1.2	-0.6	-1.5	-2.3	0.3	-0.6	-0.5	-1.0	-0.8	-1.5
Ever highly irritable/argumentative for 2 days	0.7	0.9	5.0	0.1	-0.9	-0.4	-0.9	0.2	0.9	0.7	-1.6	-2.2	-0.6	-0.9	-0.6	0.4	-0.4	-1.1	-0.9	-0.4	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	2.9	-0.6	-0.7	-0.2	0.8	0.6	1.2	1.0	-1.2	-0.7	1.1	-1.1	-0.9	0.9	0.8	1.0	1.0	-1.7	0.1
Qualifications: College or University degree	0.7	2.1	8.0	1.4	1.5	1.2	-0.5	-1.0	-0.5	-0.2	2.4	-0.2	0.5	1.7	2.6	-0.4	2.8	1.0	1.2	1.0	1.7
Whole body fat mass	0.7	2.8	7.3	0.2	-0.7	-0.7	-0.3	2.1	0.1	0.7	-0.8	-1.8	-2.5	-2.0	-2.0	-0.4	-1.9	-2.7	-2.4	-1.7	-2.7
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	6.6	-0.8	0.7	1.1	-0.7	-0.9	-0.5	-0.6	-0.6	0.7	-0.7	1.0	0.3	-0.3	0.8	0.1	-1.2	2.6	-0.6
Illnesses of father: Heart disease	0.7	1.0	3.1	-1.1	-1.3	-1.2	0.2	-0.3	1.1	0.9	-0.7	0.0	-1.3	-1.5	-0.5	0.9	-0.5	0.0	-1.4	1.1	-1.8
Whole body fat-free mass	0.7	3.8	11.3	-1.1	-0.1	-0.9	-3.3	-3.4	1.6	0.6	-1.2	-1.5	-2.1	-1.2	0.5	1.2	3.2	0.9	-2.7	1.6	-3.0
Osteoporosis (self-reported)	0.7	0.8	5.7	0.1	-2.4	-1.0	-1.0	0.3	1.1	0.0	-0.5	-1.1	0.3	-0.7	-1.3	0.8	-0.8	-0.1	-0.0	-0.2	-0.6
Medication: Gliclazide	0.7	0.8	2.8	0.2	-0.2	0.1	-1.3	1.5	0.0	1.0	0.3	-1.7	0.5	0.0	-1.2	-0.3	-1.4	-1.7	0.2	-0.0	0.3
Whole body water mass	0.7	3.8	11.2	-1.1	-0.1	-0.9	-3.1	-3.3	1.5	0.6	-1.1	-1.4	-2.2	-1.2	0.5	1.1	3.3	0.8	-2.8	1.5	-3.0
Average weekly beer plus cider intake	0.7	1.0	3.4	-0.1	-0.7	-0.8	1.8	1.2	0.3	1.0	0.8	1.3	0.7	-0.8	-1.8	0.5	-1.4	0.3	0.9	-1.0	0.3
Fractured/broken bones in last 5 years	0.7	0.9	4.3	0.6	-0.0	-0.8	0.1	2.1	0.4	0.4	0.9	-1.8	1.1	-0.4	-0.5	0.2	-0.5	-0.7	1.1	-1.7	0.4
Arm predicted mass (left)	0.7	3.7	11.1	-1.2	-0.9	-1.2	-3.3	-2.6	2.1	1.6	-1.4	-1.8	-1.7	-1.8	-0.1	1.7	2.3	0.5	-2.5	1.0	-3.3
Body Mass Index (BMI) (2010)	0.6	0.8	2.6	-1.6	-0.2	-0.3	-0.5	-1.5	0.3	-0.4	-1.1	-0.5	-1.2	-0.6	-0.5	0.5	1.1	0.3	-1.5	0.2	-1.4
Triglycerides	0.6	1.1	3.0	0.8	0.9	0.6	1.2	0.2	-1.7	-0.5	1.1	0.8	1.1	1.0	0.2	-1.4	-1.2	0.2	1.3	0.2	1.7
Hypothyroidism (self reported)	0.6	1.4	4.3	-0.7	-0.5	-0.0	-0.8	1.7	1.1	1.8	-2.1	-0.9	0.3	-1.8	-0.9	0.7	-1.7	-0.4	-0.2	-1.6	-1.4
Relative age voice broke	0.6	0.9	4.2	0.0	2.1	1.5	1.0	-0.3	-0.4	0.3	0.0	1.0	0.6	0.6	1.4	-0.5	1.0	0.9	1.0	0.1	1.1
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	2.8	-0.0	0.3	1.5	0.7	-0.3	-0.5	-0.9	-1.7	-0.8	-0.9	0.0	0.1	-0.7	1.3	0.5	-1.0	-0.9	-0.4
Serious illness, injury or assault to yourself	0.6	0.7	2.8	0.8	0.8	0.4	0.7	1.5	-0.5	0.2	0.4	-1.5	-0.4	0.6	0.1	-0.8	1.0	-1.7	-0.1	-0.7	0.3
Hair/balding pattern: Pattern 2	0.6	0.8	3.6	-0.8	-0.3	-0.1	-0.6	-1.5	0.3	0.5	0.0	0.4	1.7	0.3	0.4	0.4	-0.8	1.9	0.9	1.2	0.9
Ever unenthusiastic/disinterested for a whole week	0.6	0.8	3.4	0.3	-0.6	0.4	-0.4	0.5	0.5	0.4	-1.8	-1.3	-0.5	-1.0	-1.2	0.1	0.9	-0.5	-0.5	-1.6	-0.4
Pain all over the body in last month	0.6	0.7	2.9	-1.0	1.7	-0.7	0.4	-0.6	-0.3	-0.6	0.9	0.8	-0.8	0.4	-0.1	-0.2	0.5	0.5	-0.9	1.6	-0.7
Weight	0.6	2.8	11.3	-0.3	-0.8	-1.0	-2.2	-0.2	1.0	0.9	-1.5	-2.4	-2.5	-2.1	-1.4	0.5	0.1	-1.5	-2.8	-0.4	-3.4
Trunk fat-free mass	0.6	3.7	12.5	-0.8	0.0	-0.9	-3.5	-3.3	1.6	0.8	-1.1	-1.8	-1.6	-1.1	0.9	1.2	3.5	0.8	-2.2	1.7	-2.7
Hip circumference	0.6	2.7	10.8	-0.0	-0.7	-1.5	-1.3	0.5	1.3	1.2	-1.1	-2.0	-2.2	-2.5	-2.0	0.9	-0.3	-1.6	-2.2	-1.1	-3.3
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	2.5	1.1	0.9	0.5	1.1	1.1	-0.5	0.4	1.2	-0.4	-0.4	0.8	0.7	-0.4	1.6	-1.3	0.3	-0.6	0.5
Depression (self-reported)	0.6	0.7	3.3	0.3	-0.2	-0.1	1.5	1.8	0.1	-0.2	-0.8	-0.4	-0.4	-0.8	-1.0	0.0	-0.4	-1.3	-0.3	-1.1	-0.7
Trunk predicted mass	0.6	3.6	12.9	-0.7	0.1	-0.8	-3.4	-3.3	1.5	0.8	-1.1	-1.7	-1.6	-1.1	0.9	1.2	3.6	0.8	-2.2	1.7	-2.7
Standing height	0.6	5.9	17.6	4.2	2.8	0.9	1.4	3.4	1.0	3.9	0.8	-2.4	1.7	-1.1	3.0	0.5	2.7	-2.5	3.7	-1.3	1.2
Tense / ‘highly strung’	0.6	1.1	5.5	1.1	-1.3	-1.2	-0.2	0.9	0.3	0.2	-1.1	-2.4	-0.4	-1.4	-1.2	0.4	-0.2	-1.4	-0.1	-0.9	-0.9
Blood clot in the leg (DVT)	0.6	0.7	1.9	0.3	-1.1	-0.8	-0.3	0.6	1.0	1.3	-0.9	-1.1	0.6	-1.4	-0.4	0.9	0.2	0.1	0.7	-1.3	-0.3
Medication: Ventolin 100micrograms inhaler	0.6	0.8	2.4	0.9	-0.1	-1.0	0.6	-0.7	0.8	0.8	-0.2	0.2	0.8	-1.1	-0.6	0.7	1.4	1.5	1.4	-1.3	0.3
Number of full brothers	0.6	0.7	2.4	-0.6	0.6	0.2	1.2	0.6	0.5	1.0	-0.8	-1.1	1.5	-0.4	-0.4	0.5	-1.3	-1.0	1.3	-0.6	0.5
Medication: Omeprazole	0.6	0.7	3.7	-0.1	-0.9	-0.2	0.1	-0.2	-0.9	-1.9	-0.6	0.4	-1.4	-0.1	-1.5	-0.5	-0.6	0.2	-1.1	0.2	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	1.5	-0.3	0.7	0.1	-1.2	-1.0	-0.7	-1.2	-0.3	0.5	1.2	1.0	0.1	-0.4	0.6	0.9	0.9	1.2	1.0
Illnesses of siblings: Diabetes	0.6	0.7	2.1	0.4	0.7	0.1	0.9	1.2	-0.5	0.1	-1.0	-0.4	-0.9	-1.0	-1.0	-0.6	-1.2	-1.5	-0.5	0.7	-1.2
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	4.5	1.3	0.9	0.2	0.3	2.1	0.7	2.0	0.6	-0.7	1.6	0.3	1.0	0.2	0.3	-1.5	1.9	0.1	0.9
Basal metabolic rate	0.6	3.3	10.5	-1.0	-0.3	-1.0	-2.9	-2.6	1.5	0.8	-1.3	-1.7	-2.3	-1.5	0.0	1.1	2.5	0.2	-2.9	1.1	-3.2
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	4.4	-0.1	-0.6	0.1	-0.2	-0.2	-1.1	-2.1	-0.6	-0.1	-1.1	0.0	-1.5	-0.9	-0.9	-0.0	-0.9	-0.0	-0.1
Alcohol drinker status: Previous	0.6	0.6	2.0	-0.7	0.4	0.1	1.4	-0.8	-0.6	-0.7	0.5	1.0	-1.4	0.3	0.2	-0.5	0.7	-0.6	-1.2	0.7	-1.0
Ovarian Cancer	0.5	0.6	2.5	1.3	0.3	0.4	0.9	0.7	-0.8	-0.5	1.4	-0.7	-0.3	0.4	-0.2	-0.9	-0.0	-0.5	0.2	-1.6	0.7
Crohns Disease (2012)	0.5	0.7	2.4	0.5	1.1	0.7	0.7	0.7	-1.2	-0.7	0.2	0.6	0.8	1.1	0.4	-1.1	-1.6	-0.0	0.7	0.5	1.2
Height	0.5	9.9	41.5	6.4	3.3	3.1	1.7	4.4	-0.5	3.5	-0.1	-3.3	0.6	-0.3	3.2	-1.3	3.6	-4.8	3.8	-1.8	2.1
Lung FEV1/FVC ratio	0.5	2.4	11.0	-2.7	0.0	0.2	-2.2	-3.3	-0.1	-1.4	-0.6	0.5	0.5	1.5	1.2	0.3	0.6	2.7	-1.1	2.0	0.2
Hearing difficulty/problems: Yes	0.5	0.8	3.5	1.1	0.3	-0.3	0.6	1.4	-1.3	-0.8	1.9	-0.5	0.4	0.5	0.3	-1.2	0.0	-0.9	1.0	0.1	1.0
Systolic blood pressure, automated reading	0.5	1.4	7.9	2.8	-0.3	0.9	1.2	1.5	-1.5	-0.0	0.2	0.7	-1.4	-0.4	0.4	-1.4	-0.3	-0.8	0.4	-2.2	0.3
Severe depression (siblings)	0.5	0.6	2.0	1.0	1.4	0.2	1.0	1.1	-0.8	-0.4	0.6	-0.2	-0.1	0.4	-0.4	-1.0	-0.2	-0.5	0.3	-1.3	0.9
Leg fat-free mass (left)	0.5	2.6	8.2	-0.9	0.3	-0.7	-2.2	-2.6	1.0	0.2	-0.7	-1.0	-2.5	-1.0	0.3	0.7	2.6	0.4	-2.9	1.0	-2.8
Leg predicted mass (left)	0.5	2.7	8.3	-0.9	0.2	-0.7	-2.2	-2.5	1.1	0.3	-0.8	-1.1	-2.5	-1.1	0.3	0.8	2.5	0.3	-2.9	0.9	-2.9
Allergy	0.5	1.0	5.0	0.6	-0.5	1.5	0.9	0.3	-1.6	-1.2	-0.3	2.2	-1.5	0.6	0.2	-1.2	-0.4	0.5	-1.1	0.1	-0.4
Time employed in main current job	0.5	0.5	4.2	0.3	-0.4	1.2	2.0	0.3	-0.5	0.1	-1.0	0.8	0.0	-0.1	0.4	-0.4	0.8	0.1	0.4	-0.7	0.0
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.9	3.5	0.8	0.7	0.6	1.9	1.5	-0.9	-0.6	0.5	0.0	-1.4	0.0	-0.7	-1.3	0.3	-1.1	-0.7	-1.1	-0.1
Hair/balding pattern: Pattern 3	0.5	0.7	3.6	0.7	-0.4	-0.6	0.6	0.5	0.0	-0.1	0.3	-1.4	-1.1	-0.4	-0.6	-0.0	1.3	-1.9	-0.9	-0.9	-1.0
Noisy workplace	0.5	0.6	2.2	-0.2	-0.0	-0.4	0.5	0.6	0.7	1.2	0.2	0.3	1.5	-0.0	1.0	0.5	-0.8	0.2	1.4	0.9	0.8
Medication: Paracetamol	0.5	0.8	4.0	0.8	0.4	0.6	1.9	1.4	-0.1	0.2	-0.5	0.1	-0.5	-0.1	-0.3	-0.0	1.1	-0.8	0.2	-2.0	0.5
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	5.2	-0.5	0.2	-0.2	0.2	1.8	0.3	1.6	-0.6	-0.8	0.7	-1.1	-0.3	0.3	-2.3	-0.7	0.6	-1.1	-0.4
Medication: Seretide 50 evohaler	0.5	0.5	1.6	0.8	-0.7	0.3	-1.0	0.5	0.5	1.0	-1.3	-0.3	1.0	-0.4	-0.3	0.4	-0.1	-0.4	1.2	-0.1	0.9
Mean time to correctly identify matches	0.5	0.9	3.1	-0.7	1.2	1.0	0.9	-1.5	-0.7	-0.7	-1.4	0.4	0.7	0.3	0.7	-0.6	1.1	1.8	0.5	-0.5	1.2
Had major operations	0.5	0.6	2.5	1.1	0.6	0.6	1.0	1.6	-0.8	-1.2	0.4	1.2	-0.7	0.6	0.3	-0.9	-0.2	-0.7	-0.1	-0.1	0.2
Smoking status: Previous	0.5	0.7	2.6	-0.4	-0.5	-0.7	1.5	0.9	0.4	0.8	-1.0	-0.8	0.7	-1.2	-0.7	0.6	-1.6	-0.7	0.6	-0.0	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.5	0.7	3.1	-0.4	-0.7	-0.4	0.6	-0.1	0.1	-0.1	-1.7	-0.8	-0.3	-1.1	-1.8	0.5	0.1	0.6	-0.7	-1.7	-0.7
Illnesses of father: None of the above (group 1)	0.5	0.6	3.6	-0.1	0.4	0.2	-0.4	-0.3	0.4	0.5	-0.4	-0.2	1.9	0.6	0.7	0.6	0.2	0.6	1.7	-0.3	1.3
Financial situation satisfaction	0.5	0.7	3.1	-0.2	0.3	-0.3	0.0	1.4	0.6	1.8	0.4	-1.5	0.0	-0.9	-0.3	0.4	-0.0	-1.0	0.1	-1.2	-0.4
Diastolic blood pressure, automated reading	0.5	1.5	7.1	0.3	-1.0	0.3	-1.1	-0.9	-0.7	-0.7	-1.7	-1.3	-2.0	-0.9	-1.0	-1.0	-0.3	0.1	-1.9	-2.7	-0.8
Pack years of smoking	0.5	0.7	3.0	-0.9	-0.8	0.3	-0.1	0.3	-0.9	-1.1	-0.7	-0.6	-1.2	0.1	-1.7	-0.9	-0.4	-0.3	-1.6	-0.1	-0.6
Intelligence (Savage-Jansen 2018)	0.4	1.1	4.1	0.8	1.6	0.6	0.1	-1.7	-0.4	-1.2	1.3	0.5	-0.6	1.1	1.8	-0.6	2.0	1.0	-0.3	0.2	0.8
Alzheimer’s Disease (in mother)	0.4	0.5	2.4	-0.3	-0.2	-0.3	-1.1	-0.7	-0.5	-1.3	-0.5	-1.6	-0.2	0.1	-1.0	-0.3	-0.3	0.4	-0.7	-0.4	0.1
Crohns Disease (2017)	0.4	0.9	2.4	0.0	1.1	-0.1	1.4	0.7	-1.2	-0.5	1.6	0.3	1.0	0.7	0.3	-1.2	-1.5	0.0	1.3	0.1	1.2
Irritable Bowel Disease (IBD)	0.4	1.0	2.9	0.2	0.9	0.3	1.2	-0.9	-1.7	-1.3	1.1	1.3	0.0	1.2	0.8	-1.5	-0.9	1.0	0.3	1.0	1.0
Ulcerative Colitis (UC)	0.4	0.7	1.8	0.5	-0.1	0.3	0.8	-1.3	-1.3	-1.3	-0.0	1.2	-0.8	0.8	0.2	-1.1	-0.4	1.0	-0.6	1.0	0.3
LDL Cholesterol	0.4	0.7	3.5	0.0	0.2	0.3	1.1	1.5	-0.1	0.8	0.9	0.8	0.5	0.7	0.3	-0.3	-1.9	-1.3	0.5	0.8	0.5
Blood White Count	0.4	3.0	23.5	-1.1	-0.3	-1.2	-1.1	2.8	0.5	0.7	0.1	-1.2	0.6	-0.6	-2.6	0.6	-4.8	-2.6	-0.1	1.0	-1.0
Waist Hip Ratio (WHR)	0.4	2.0	8.8	-0.2	0.1	-0.5	0.9	3.0	0.2	1.3	0.8	-1.3	1.9	0.1	-0.4	-0.1	-2.8	-2.4	1.9	-0.5	1.1
Sensitivity / hurt feelings	0.4	0.7	2.1	1.1	-0.3	-1.1	0.7	1.4	0.4	0.3	1.2	-0.8	0.8	-0.3	-0.6	0.1	-0.9	-1.2	1.0	-1.0	0.2
Relative age of first facial hair	0.4	0.8	3.8	-0.7	0.9	0.6	0.7	-0.4	0.9	1.1	-1.9	0.8	0.7	-0.7	0.7	1.0	1.1	1.0	0.9	-0.7	-0.2
Ever had hysterectomy (womb removed)	0.4	0.5	1.8	0.9	0.7	1.1	0.8	0.6	-1.3	-0.4	0.6	0.5	-0.7	0.5	0.3	-1.3	-0.2	-0.4	-0.2	-0.2	0.4
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.5	-0.8	0.3	-0.8	0.1	-0.1	1.0	0.6	-0.8	0.2	-0.0	-0.6	0.3	1.2	0.6	0.1	-0.3	1.2	-0.9
Pack years adult smoking proportion	0.4	0.6	3.4	-0.9	-1.0	0.1	-0.0	0.7	-0.7	-0.6	-0.6	-0.5	-0.8	-0.1	-1.8	-0.7	-1.0	-0.7	-1.1	-0.3	-0.5
Hayfever, allergic rhinitis or eczema	0.4	0.8	2.9	-0.9	1.2	-0.9	-0.3	-0.7	0.8	0.8	1.2	-1.7	1.0	0.4	1.0	0.7	0.8	-0.9	0.7	0.2	0.6
Supplements: Glucosamine	0.4	0.6	2.4	-0.7	-0.3	-1.6	-1.0	-0.4	0.6	0.6	0.4	-0.7	0.1	-0.9	-0.6	0.7	-0.5	0.5	-0.2	1.2	-1.1
Medication: Levothyroxine sodium	0.4	0.7	2.5	0.9	1.5	0.9	1.1	1.6	-0.8	0.8	0.1	-0.2	-0.4	0.1	0.5	-0.9	-0.8	-1.2	0.2	-0.7	-0.0
Had menopause	0.4	0.5	1.6	0.2	-0.4	0.7	0.8	0.3	-1.0	-1.2	-0.8	0.4	-0.6	0.0	-0.7	-0.8	-1.3	0.2	-0.7	-1.1	0.1
Financial difficulties in last 2 years	0.4	0.6	2.1	-0.3	0.4	0.4	0.2	1.4	-0.4	-0.1	-0.3	-0.2	-1.1	-0.2	-0.9	-0.6	-1.4	-1.4	-1.0	0.0	-0.7
Fluid intelligence score	0.4	0.8	1.9	0.9	0.7	1.3	-0.2	-0.8	-0.8	-1.1	0.8	0.7	-0.2	1.2	1.0	-1.2	0.9	0.5	0.2	-0.4	1.4
Pulse rate	0.4	0.6	2.2	0.1	-0.7	0.1	-0.9	0.5	-0.0	-0.7	-1.0	-1.4	-0.7	-0.3	-1.5	-0.4	0.0	-0.8	-0.9	-1.4	-0.2
Qualifications: A levels/AS levels or equivalent	0.4	0.9	8.8	0.6	0.6	-0.0	-0.5	-0.7	0.4	0.8	0.0	-1.7	0.5	0.2	1.1	0.6	3.0	0.4	0.7	-0.1	0.5
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	2.9	0.8	0.8	0.2	0.5	0.7	-0.5	-0.5	1.7	0.4	-0.0	0.9	0.1	-0.8	-0.7	-0.1	0.2	0.5	0.6
Mouth/teeth dental problems: Dentures	0.4	0.7	3.8	-0.4	-0.9	-0.3	-1.2	-0.1	0.0	-0.3	-1.1	-2.0	0.7	-0.9	-1.0	-0.0	-1.0	-0.3	0.3	-1.2	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.3	5.6	-2.0	0.8	-0.3	-0.1	-1.4	0.9	0.8	-0.6	1.3	-0.6	-0.1	1.2	0.9	1.0	0.8	-1.1	2.4	-1.5
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	5.5	0.4	0.3	0.0	-0.5	0.3	0.3	0.4	-1.1	-2.4	0.0	-0.1	-0.4	0.4	1.5	-0.8	-0.3	-0.5	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	2.6	0.6	-0.7	1.1	-0.4	0.5	-0.7	-0.1	-1.6	-0.6	-0.3	-0.5	-0.2	-0.7	-0.6	0.3	-0.4	-1.3	-0.2
Alcohol intake frequency.	0.4	0.8	4.5	-0.4	-0.0	-0.1	0.2	-0.3	-0.5	-0.3	0.1	-0.5	-2.1	0.0	-1.2	-0.5	0.3	-1.8	-1.6	0.4	-1.1
Comparative height size at age 10	0.4	2.1	11.2	2.0	0.7	0.3	-1.1	1.4	0.3	2.1	-1.7	-3.4	1.0	-1.6	0.7	0.2	0.8	-1.9	1.6	0.1	-0.4
Age at last live birth	0.4	0.6	2.4	1.1	0.5	0.3	-0.5	-0.4	-0.2	-0.2	1.5	0.8	0.4	0.8	0.6	-0.2	1.5	0.2	1.0	0.6	0.9
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.9	-0.5	-1.3	0.2	-1.2	-0.7	-0.1	-0.9	0.1	-0.1	-1.3	-0.0	0.1	-0.3	-0.5	-0.3	-1.4	-0.3	-0.9
Commuting to job workplace: Walk	0.4	0.5	2.4	0.4	-0.0	1.2	1.6	0.1	-1.0	-0.4	-1.2	-0.6	-0.2	-0.3	0.1	-0.8	-0.6	0.2	0.0	-0.7	0.2
Average weekly champagne plus white wine intake	0.4	0.6	2.4	0.3	-0.1	-0.2	-0.3	-0.3	1.1	0.9	0.5	0.5	1.5	0.2	0.7	1.0	-0.0	0.9	1.4	-0.5	0.6
Alcohol drinker status: Never	0.4	0.5	1.6	0.5	-0.2	0.3	-1.2	-0.8	-1.2	-1.3	-0.1	-0.2	-0.3	0.7	-0.9	-1.1	0.1	0.0	-0.4	0.4	0.4
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	1.4	0.2	-0.9	-0.7	-0.3	0.5	0.8	1.1	-0.8	-0.9	0.9	-1.2	-0.2	0.8	0.2	0.5	0.9	-0.9	-0.1
Alzheimer’s Disease (including proxy)	0.3	0.5	1.3	-0.6	-0.8	-0.1	-1.1	-0.8	-0.5	-1.1	-0.8	-0.9	-0.4	-0.3	-0.7	0.0	0.2	0.8	-0.9	-0.2	-0.6
Verbal and Numeric Reasoning (VNR)	0.3	0.7	1.7	0.5	1.2	0.2	1.3	-0.7	-0.8	-1.1	1.3	1.1	-1.2	0.5	0.6	-1.0	1.0	0.4	-0.7	0.0	0.2
Blood Eosinophil Count	0.3	2.6	15.4	0.4	-0.7	-1.4	-0.1	2.1	0.2	0.8	0.0	-0.9	-0.4	-1.1	-2.1	0.2	-3.9	-3.9	-0.3	0.3	-1.3
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.6	-1.1	0.6	0.4	-0.4	0.1	-0.0	-0.6	-1.3	0.6	-0.5	-0.2	0.2	-0.3	-0.7	0.9	-1.1	0.1	-0.7
Diabetes (father)	0.3	0.4	2.7	-0.3	1.6	-0.6	-0.5	0.2	0.7	1.0	0.4	-0.7	0.5	-0.2	0.4	0.6	-0.1	-0.8	0.1	0.5	-0.4
Stomach or abdominal pain in last month	0.3	0.4	1.4	-0.6	-0.1	-0.5	0.5	0.9	0.8	1.2	-0.1	-0.2	0.5	-0.5	0.3	0.7	-1.1	-0.1	0.3	-0.3	-0.1
Forced vital capacity (FVC)	0.3	1.2	5.1	-1.2	0.7	-0.8	0.1	-1.4	1.2	1.0	0.1	1.5	-0.3	-0.4	1.0	1.1	1.2	0.9	-0.5	2.3	-1.3
Medication: Lansoprazole	0.3	0.4	1.3	0.1	0.7	0.1	0.9	0.8	-1.0	-0.8	0.4	-0.0	0.2	0.3	-0.3	-0.9	-1.1	-0.7	0.3	-0.2	0.4
Hair/balding pattern: Pattern 4	0.3	0.8	2.8	1.3	1.4	0.7	1.7	1.5	-0.9	-0.3	0.2	1.2	-0.4	0.1	1.0	-0.8	0.2	0.3	0.6	-0.7	0.7
Gout (self-reported)	0.3	0.4	2.8	-0.5	0.4	-0.4	0.9	-0.5	-0.4	-0.2	-0.6	0.5	-1.7	-0.6	-0.3	0.1	0.3	-0.3	-0.9	0.3	-0.9
Medication: Ibuprofen	0.3	0.4	1.6	0.5	0.9	0.2	0.5	0.8	-0.4	0.0	1.3	-0.5	-0.5	0.7	0.4	-0.3	1.1	-1.1	-0.2	-0.3	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	1.6	-1.3	-0.1	-0.6	-0.1	0.0	0.3	0.2	-0.9	-0.8	0.4	-0.3	-0.8	0.1	-0.9	-1.1	-0.1	0.4	-0.8
Pulse rate, automated reading	0.3	0.9	6.1	-0.6	-1.3	-0.7	0.3	-0.1	-0.2	-0.7	0.1	-0.7	-0.7	-0.4	-2.5	-0.1	-0.5	0.1	-1.3	-1.9	-0.2
Family relationship satisfaction	0.3	0.3	3.1	-0.2	0.4	0.3	-1.8	-0.0	-0.0	-0.1	-0.4	-1.3	0.1	0.3	0.5	-0.3	-0.3	-0.3	-0.2	0.4	0.1
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.2	0.9	-0.5	-0.2	0.6	-0.3	0.2	0.1	0.3	1.1	-0.1	-0.7	0.6	0.6	1.0	0.8	0.5	-0.6	0.1
Back pain experienced in last month	0.3	0.5	2.4	0.4	-1.0	0.3	-0.3	0.2	-0.9	-1.6	-0.8	0.1	-0.4	-0.2	-1.0	-1.1	-0.1	-0.1	-0.5	0.4	-0.4
Hearing aid user	0.3	0.4	2.1	0.6	0.1	0.0	-1.2	0.4	0.0	-0.3	-0.8	-0.9	-0.5	-0.1	-0.2	0.0	0.6	-1.5	-0.1	-0.4	-0.2
Medication: Paracetamol	0.3	0.5	2.5	0.3	0.4	0.4	1.4	0.7	-0.4	-0.7	-0.3	0.3	-0.6	0.1	-0.4	-0.0	1.3	-0.0	-0.2	-1.6	0.5
Reaction Time	0.2	0.4	1.8	-0.4	0.9	0.4	1.3	-0.5	-0.6	-0.3	-1.2	0.3	0.6	0.1	0.1	-0.4	0.0	0.6	0.5	-0.3	0.8
Coronary Artery Disease (CAD)	0.2	0.2	1.2	0.2	-0.2	-0.3	-0.2	0.7	0.3	1.1	-0.6	0.1	0.3	-0.7	-0.3	0.4	-0.2	0.1	0.4	0.1	-0.4
Allergy or Eczema	0.2	0.5	2.9	-0.5	0.3	-0.4	-0.1	-1.3	0.4	0.4	0.8	-1.1	0.4	-0.0	1.2	0.0	1.7	0.4	0.5	-0.3	0.6
Respiratory disease	0.2	0.5	4.7	2.2	-0.4	-0.3	0.1	0.9	-0.3	-0.2	0.0	0.2	-0.4	-0.5	-0.9	-0.7	-0.5	-0.3	0.7	-0.9	0.5
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.9	0.7	0.9	0.1	0.7	-0.7	-0.5	-0.6	0.2	0.1	-0.2	-0.2	0.1	-0.3	0.7	0.1	0.2	-0.3	0.0
Asthma	0.2	0.4	1.9	0.5	0.1	-1.2	-0.4	-0.1	0.2	-0.3	-0.0	-0.8	1.0	-0.5	-1.4	0.1	-0.5	0.6	0.8	0.3	0.4
Birth weight	0.2	0.4	1.1	0.2	1.0	-0.4	-0.4	0.6	0.5	-0.2	-0.8	-1.1	-0.6	-0.7	-0.2	0.5	-0.1	0.1	-0.9	0.3	-0.9
Forced vital capacity (FVC), Best measure	0.2	0.7	3.2	-0.6	1.1	-0.2	0.5	-0.5	0.8	0.9	-0.1	1.1	-0.4	-0.1	1.1	0.7	1.2	0.3	-0.2	1.8	-0.8
Supplements: Vitamin C	0.2	0.2	1.3	0.0	-0.8	-0.6	-0.5	-0.3	0.4	0.1	0.5	-0.7	0.2	-0.3	0.3	0.4	1.1	-0.0	0.3	0.2	-0.0
Asthma (self-reported)	0.2	0.4	2.1	0.6	0.1	-1.3	-0.3	-0.1	0.3	-0.1	0.0	-0.9	0.7	-0.8	-1.5	0.2	-0.2	0.7	0.7	0.1	0.1
Number of operations (self-reported)	0.2	0.4	1.4	-0.4	0.4	-0.4	0.9	-0.6	-0.2	-0.2	-0.2	1.2	0.3	0.2	-0.3	0.6	1.1	1.0	0.2	0.8	0.1
Ever had prostate specific antigen (PSA) test	0.2	0.3	0.8	0.7	-0.4	0.3	-0.1	0.2	-0.6	-0.5	0.4	-0.6	-0.2	0.6	0.1	-0.7	0.9	-0.6	-0.2	-0.9	0.3
Supplements: Calcium	0.2	0.2	1.2	-0.4	0.3	-0.7	1.1	-0.1	0.3	0.1	0.9	0.1	0.1	-0.5	-0.0	0.6	0.0	0.5	0.0	0.6	-0.5
Hair Pigment	0.1	3.6	11.0	1.6	2.3	2.4	-0.6	-0.6	-2.2	-1.4	2.1	2.0	0.1	3.3	2.5	-2.3	0.8	-0.6	1.2	1.1	2.9
Irritability	0.1	0.1	0.6	0.2	-0.0	-0.5	-0.4	-0.2	-0.2	-0.4	-0.4	-0.0	-0.3	-0.3	-0.3	-0.3	-0.6	-0.8	-0.2	0.6	-0.3
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Tanning	0.0	0.4	2.5	-0.9	-0.3	-0.5	1.6	-0.0	0.5	0.3	0.1	-0.6	-0.3	-0.2	0.1	0.3	-0.3	0.4	-0.3	-1.2	0.1

Hub : Genes

TMEM106C

Models

Trait associations