Best TWAS P=9.15e-08 · Best GWAS P=3.78e-06 conditioned to 0.23
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | CRYL1 | 0.27 | 0.00 | lasso | 11 | 0.00 | 0.34400 | -4.4 | -5.3 | 9.2e-08 | 0.71 | 0.01 | 0.31 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | IFT88 | 0.04 | 0.03 | blup | 83 | 0.03 | 0.00022 | 3.5 | 5.3 | 1.2e-07 | -0.50 | 0.06 | 0.31 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | IFT88 | 0.05 | 0.00 | blup | 85 | 0.02 | 0.00213 | 2.3 | 5.3 | 1.0e-07 | -0.61 | 0.01 | 0.14 | FALSE |