Best TWAS P=8.14e-08 · Best GWAS P=1.02e-09 conditioned to 0.522
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Skin Not Sun Exposed Suprapubic | RP11-104N10.1 | 0.11 | 0.04 | lasso | 4 | 0.03 | 5.2e-03 | -4.9 | -5.2 | 2.4e-07 | -0.86 | 0.12 | 0.54 | FALSE |
2 | GTEx | Whole Blood | ANKRD11 | 0.07 | 0.05 | lasso | 2 | 0.04 | 2.4e-04 | 5.4 | -5.4 | 8.1e-08 | -0.83 | 0.05 | 0.94 | TRUE |
3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | ZNF276 | 0.09 | 0.02 | enet | 12 | 0.05 | 2.3e-05 | 4.1 | -5.1 | 3.1e-07 | -0.26 | 0.00 | 0.05 | TRUE |