[Hub]/) : Traits : Hand grip strength (right) :

chr16:69,062,879-70,473,934

Best TWAS P=5.32e-11 · Best GWAS P=9.61e-11 conditioned to 0.0256

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Thyroid NOB1 0.03 0.01 enet 6 0.02 7.7e-03 -5.6 6.6 5.3e-11 0.77 0.04 0.86 TRUE
2 GTEx Thyroid CTD-2033A16.3 0.03 0.02 enet 7 0.02 6.7e-03 -4.2 6.0 1.9e-09 0.69 0.10 0.65 FALSE
3 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma CLEC18A 0.10 0.06 lasso 2 0.04 6.3e-03 5.6 5.6 1.8e-08 0.53 0.03 0.42 FALSE
4 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma PDXDC2 0.20 0.02 blup 26 0.07 1.8e-04 5.0 5.4 8.0e-08 0.46 0.06 0.37 FALSE
5 The Cancer Genome Atlas Colon Adenocarcinoma CLEC18A 0.14 0.18 lasso 5 0.15 4.5e-09 5.6 5.9 3.6e-09 0.56 0.05 0.95 FALSE
6 The Cancer Genome Atlas Glioblastoma Multiforme PDXDC2 0.10 0.12 lasso 3 0.10 4.7e-04 5.6 5.6 1.8e-08 0.53 0.01 0.85 FALSE
7 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PDXDC2 0.14 0.05 enet 6 0.05 3.2e-06 4.9 5.5 3.3e-08 0.42 0.12 0.85 FALSE
8 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CLEC18A 0.06 0.10 lasso 1 0.09 6.9e-11 5.6 5.6 2.1e-08 0.53 0.08 0.92 FALSE
9 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma PDXDC2 0.09 0.01 blup 26 0.06 4.7e-05 4.8 5.5 3.0e-08 0.47 0.02 0.87 FALSE
10 The Cancer Genome Atlas Rectum Adenocarcinoma CLEC18A 0.15 0.03 blup 23 0.09 4.3e-03 5.0 5.8 5.0e-09 0.63 0.01 0.47 FALSE
11 The Cancer Genome Atlas Soft Tissue Sarcoma CLEC18A 0.12 0.11 lasso 2 0.11 3.4e-07 5.8 5.9 4.6e-09 0.56 0.04 0.96 FALSE
12 The Cancer Genome Atlas Soft Tissue Sarcoma PDXDC2 0.05 0.01 blup 26 0.03 9.5e-03 4.9 6.1 1.1e-09 0.55 0.02 0.54 FALSE
13 The Cancer Genome Atlas Skin Cutaneous Melanoma CLEC18A 0.17 0.09 enet 8 0.11 8.5e-04 5.0 6.2 7.3e-10 0.63 0.01 0.82 FALSE
14 The Cancer Genome Atlas Testicular Germ Cell Tumors CLEC18A 0.20 0.09 lasso 5 0.08 8.8e-04 6.0 6.1 1.1e-09 0.70 0.01 0.90 FALSE