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chr16:69,062,879-70,473,934

Best TWAS P=5.32e-11 · Best GWAS P=9.61e-11 conditioned to 0.0256

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Thyroid	NOB1	0.03	0.01	enet	6	0.02	7.7e-03	-5.6	6.6	5.3e-11	0.77	0.04	0.86	TRUE
13	The Cancer Genome Atlas	Skin Cutaneous Melanoma	CLEC18A	0.17	0.09	enet	8	0.11	8.5e-04	5.0	6.2	7.3e-10	0.63	0.01	0.82	FALSE
12	The Cancer Genome Atlas	Soft Tissue Sarcoma	PDXDC2	0.05	0.01	blup	26	0.03	9.5e-03	4.9	6.1	1.1e-09	0.55	0.02	0.54	FALSE
14	The Cancer Genome Atlas	Testicular Germ Cell Tumors	CLEC18A	0.20	0.09	lasso	5	0.08	8.8e-04	6.0	6.1	1.1e-09	0.70	0.01	0.90	FALSE
2	GTEx	Thyroid	CTD-2033A16.3	0.03	0.02	enet	7	0.02	6.7e-03	-4.2	6.0	1.9e-09	0.69	0.10	0.65	FALSE
5	The Cancer Genome Atlas	Colon Adenocarcinoma	CLEC18A	0.14	0.18	lasso	5	0.15	4.5e-09	5.6	5.9	3.6e-09	0.56	0.05	0.95	FALSE
11	The Cancer Genome Atlas	Soft Tissue Sarcoma	CLEC18A	0.12	0.11	lasso	2	0.11	3.4e-07	5.8	5.9	4.6e-09	0.56	0.04	0.96	FALSE
10	The Cancer Genome Atlas	Rectum Adenocarcinoma	CLEC18A	0.15	0.03	blup	23	0.09	4.3e-03	5.0	5.8	5.0e-09	0.63	0.01	0.47	FALSE
3	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	CLEC18A	0.10	0.06	lasso	2	0.04	6.3e-03	5.6	5.6	1.8e-08	0.53	0.03	0.42	FALSE
6	The Cancer Genome Atlas	Glioblastoma Multiforme	PDXDC2	0.10	0.12	lasso	3	0.10	4.7e-04	5.6	5.6	1.8e-08	0.53	0.01	0.85	FALSE
8	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CLEC18A	0.06	0.10	lasso	1	0.09	6.9e-11	5.6	5.6	2.1e-08	0.53	0.08	0.92	FALSE
9	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	PDXDC2	0.09	0.01	blup	26	0.06	4.7e-05	4.8	5.5	3.0e-08	0.47	0.02	0.87	FALSE
7	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PDXDC2	0.14	0.05	enet	6	0.05	3.2e-06	4.9	5.5	3.3e-08	0.42	0.12	0.85	FALSE
4	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	PDXDC2	0.20	0.02	blup	26	0.07	1.8e-04	5.0	5.4	8.0e-08	0.46	0.06	0.37	FALSE