[Hub]/) : Traits : Hand grip strength (right) :

chr17:36,211,659-37,644,854

Best TWAS P=4.95e-17 · Best GWAS P=1.02e-13 conditioned to 0.105

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PIP4K2B 0.15 0.07 lasso 5 0.07 2.2e-06 -7.4 -7.3 2.6e-13 0.95 0.00 1.00 FALSE
2 GTEx Artery Aorta PSMB3 0.23 0.17 enet 26 0.22 2.1e-12 -7.4 -6.2 4.7e-10 0.84 0.00 1.00 FALSE
3 GTEx Artery Tibial PSMB3 0.10 0.02 enet 12 0.03 1.2e-03 -7.4 -6.0 2.4e-09 0.73 0.00 0.99 FALSE
4 GTEx Artery Tibial PIP4K2B 0.37 0.16 enet 49 0.22 2.1e-17 -7.4 -8.4 4.9e-17 0.76 0.00 1.00 TRUE
5 GTEx Testis PSMB3 0.30 0.24 lasso 4 0.21 8.9e-10 -7.4 -7.6 3.9e-14 1.00 0.00 1.00 FALSE
6 NTR Blood PIP4K2B 0.02 0.01 lasso 3 0.01 6.4e-04 -7.4 7.1 1.3e-12 -0.97 0.00 0.99 FALSE
7 YFS Blood PSMB3 0.14 0.11 enet 31 0.16 7.2e-49 -7.3 -6.3 3.6e-10 0.81 0.00 1.00 FALSE
8 The Cancer Genome Atlas Bladder Urothelial Carcinoma PSMB3 0.04 0.00 blup 37 0.02 6.7e-03 -2.9 -5.6 2.1e-08 0.72 0.01 0.69 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PSMB3 0.14 0.05 blup 42 0.05 8.9e-07 -7.3 -5.5 3.2e-08 0.70 0.00 1.00 FALSE
10 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PSMB3 0.12 0.02 enet 14 0.05 1.3e-03 -6.2 -5.8 6.5e-09 0.63 0.00 0.80 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma PIP4K2B 0.05 0.04 blup 56 0.05 5.3e-06 -6.2 -7.1 1.4e-12 0.86 0.00 0.99 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma PSMB3 0.11 0.07 blup 42 0.07 9.4e-08 -7.4 -6.0 1.5e-09 0.77 0.00 1.00 FALSE
13 The Cancer Genome Atlas Testicular Germ Cell Tumors PSMB3 0.12 0.09 lasso 3 0.06 3.0e-03 -7.3 -7.2 4.5e-13 0.97 0.00 0.94 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma PSMB3 0.05 0.06 lasso 1 0.05 2.4e-05 -7.4 -7.4 1.0e-13 1.00 0.00 1.00 FALSE