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chr17:36,211,659-37,644,854

Best TWAS P=4.95e-17 · Best GWAS P=1.02e-13 conditioned to 0.105

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Artery Tibial	PIP4K2B	0.37	0.16	enet	49	0.22	2.1e-17	-7.4	-8.4	4.9e-17	0.76	0.00	1.00	TRUE
5	GTEx	Testis	PSMB3	0.30	0.24	lasso	4	0.21	8.9e-10	-7.4	-7.6	3.9e-14	1.00	0.00	1.00	FALSE
14	The Cancer Genome Atlas	Thyroid Carcinoma	PSMB3	0.05	0.06	lasso	1	0.05	2.4e-05	-7.4	-7.4	1.0e-13	1.00	0.00	1.00	FALSE
1	GTEx	Adipose Subcutaneous	PIP4K2B	0.15	0.07	lasso	5	0.07	2.2e-06	-7.4	-7.3	2.6e-13	0.95	0.00	1.00	FALSE
13	The Cancer Genome Atlas	Testicular Germ Cell Tumors	PSMB3	0.12	0.09	lasso	3	0.06	3.0e-03	-7.3	-7.2	4.5e-13	0.97	0.00	0.94	FALSE
6	NTR	Blood	PIP4K2B	0.02	0.01	lasso	3	0.01	6.4e-04	-7.4	7.1	1.3e-12	-0.97	0.00	0.99	FALSE
11	The Cancer Genome Atlas	Prostate Adenocarcinoma	PIP4K2B	0.05	0.04	blup	56	0.05	5.3e-06	-6.2	-7.1	1.4e-12	0.86	0.00	0.99	FALSE
7	YFS	Blood	PSMB3	0.14	0.11	enet	31	0.16	7.2e-49	-7.3	-6.3	3.6e-10	0.81	0.00	1.00	FALSE
2	GTEx	Artery Aorta	PSMB3	0.23	0.17	enet	26	0.22	2.1e-12	-7.4	-6.2	4.7e-10	0.84	0.00	1.00	FALSE
12	The Cancer Genome Atlas	Prostate Adenocarcinoma	PSMB3	0.11	0.07	blup	42	0.07	9.4e-08	-7.4	-6.0	1.5e-09	0.77	0.00	1.00	FALSE
3	GTEx	Artery Tibial	PSMB3	0.10	0.02	enet	12	0.03	1.2e-03	-7.4	-6.0	2.4e-09	0.73	0.00	0.99	FALSE
10	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PSMB3	0.12	0.02	enet	14	0.05	1.3e-03	-6.2	-5.8	6.5e-09	0.63	0.00	0.80	FALSE
8	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PSMB3	0.04	0.00	blup	37	0.02	6.7e-03	-2.9	-5.6	2.1e-08	0.72	0.01	0.69	FALSE
9	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PSMB3	0.14	0.05	blup	42	0.05	8.9e-07	-7.3	-5.5	3.2e-08	0.70	0.00	1.00	FALSE