[Hub]/) : Traits : Hand grip strength (right) : ← →

chr2:43,417,083-44,920,960

Best TWAS P=1.03e-08 · Best GWAS P=5.64e-09 conditioned to 0.0372

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Brain Cerebellar Hemisphere	LRPPRC	0.34	0.15	enet	13	0.10	1.5e-03	-5.8	5.7	1.0e-08	-0.80	0.02	0.90	TRUE
12	GTEx	Testis	LRPPRC	0.30	0.20	enet	16	0.19	5.3e-09	5.6	5.6	1.7e-08	-0.79	0.05	0.95	FALSE
16	The Cancer Genome Atlas	Rectum Adenocarcinoma	LRPPRC	0.27	0.12	blup	109	0.13	7.3e-04	4.0	5.6	1.7e-08	-0.80	0.06	0.72	FALSE
18	The Cancer Genome Atlas	Thyroid Carcinoma	LRPPRC	0.15	0.14	lasso	6	0.15	1.6e-14	5.4	5.6	2.3e-08	-0.72	0.05	0.94	FALSE
13	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	LRPPRC	0.06	0.04	lasso	2	0.05	2.8e-03	5.6	5.6	2.6e-08	-0.80	0.04	0.55	FALSE
5	GTEx	Brain Cortex	LRPPRC	0.17	0.10	lasso	3	0.11	4.9e-04	5.2	5.6	2.7e-08	-0.91	0.03	0.83	FALSE
7	GTEx	Colon Sigmoid	LRPPRC	0.18	0.06	lasso	3	0.04	1.3e-02	5.0	5.6	2.8e-08	-0.70	0.08	0.56	FALSE
8	GTEx	Nerve Tibial	LRPPRC	0.25	0.07	lasso	6	0.04	6.4e-04	5.2	5.5	3.9e-08	-0.84	0.08	0.92	FALSE
17	The Cancer Genome Atlas	Testicular Germ Cell Tumors	LRPPRC	0.17	0.14	lasso	6	0.13	2.3e-05	5.2	5.5	4.4e-08	-0.76	0.11	0.88	FALSE
11	GTEx	Stomach	LRPPRC	0.13	0.05	lasso	3	0.07	4.8e-04	5.1	5.5	4.5e-08	-0.78	0.10	0.86	FALSE
9	GTEx	Pancreas	LRPPRC	0.25	0.24	lasso	3	0.20	6.8e-09	5.6	5.4	7.1e-08	-0.76	0.04	0.96	FALSE
10	GTEx	Skin Sun Exposed Lower leg	LRPPRC	0.16	0.08	lasso	5	0.12	4.5e-10	5.2	5.4	8.0e-08	-0.75	0.16	0.84	FALSE
14	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	LRPPRC	0.09	0.03	blup	109	0.04	6.5e-03	5.0	5.3	9.1e-08	-0.76	0.09	0.40	FALSE
1	CommonMind	Brain Pre-frontal Cortex	LRPPRC	0.33	0.32	lasso	11	0.33	1.6e-41	5.1	5.3	9.9e-08	-0.71	0.06	0.94	FALSE
2	GTEx	Adipose Subcutaneous	LRPPRC	0.18	0.09	lasso	5	0.10	1.7e-08	5.2	5.3	1.1e-07	-0.74	0.11	0.89	FALSE
3	GTEx	Adipose Visceral Omentum	LRPPRC	0.14	0.05	enet	7	0.07	1.9e-04	5.2	5.2	1.7e-07	-0.78	0.11	0.83	FALSE
15	The Cancer Genome Atlas	Lung Adenocarcinoma	LRPPRC	0.09	0.11	lasso	3	0.10	5.6e-12	5.1	5.2	1.9e-07	-0.79	0.12	0.88	FALSE
6	GTEx	Cells EBV-transformed lymphocytes	LRPPRC	0.63	0.33	lasso	13	0.26	4.2e-09	5.2	5.2	2.1e-07	-0.72	0.13	0.87	FALSE