TWAS
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Traits
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Traits
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Hand grip strength (right)
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chr2:47,979,687-49,429,109
Best TWAS P=1.64e-08 · Best GWAS P=3.61e-09 conditioned to 1
48M
48.2M
48.4M
48.6M
48.8M
49M
49.2M
49.4M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Cells Transformed fibroblasts
PPP1R21
0.08
0.09
lasso
3
0.08
2.8e-06
5.8
5.7
1.6e-08
0.98
0.00
1.00
TRUE
1
GTEx
Artery Aorta
PPP1R21
0.19
0.06
lasso
4
0.07
6.3e-05
5.4
5.2
1.7e-07
0.81
0.03
0.97
FALSE
3
The Cancer Genome Atlas
Thyroid Carcinoma
FOXN2
0.04
0.01
blup
52
0.02
2.1e-03
5.8
-5.2
2.3e-07
-0.89
0.01
0.95
FALSE