Best TWAS P=1.64e-08 · Best GWAS P=3.61e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | PPP1R21 | 0.19 | 0.06 | lasso | 4 | 0.07 | 6.3e-05 | 5.4 | 5.2 | 1.7e-07 | 0.81 | 0.03 | 0.97 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | PPP1R21 | 0.08 | 0.09 | lasso | 3 | 0.08 | 2.8e-06 | 5.8 | 5.7 | 1.6e-08 | 0.98 | 0.00 | 1.00 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | FOXN2 | 0.04 | 0.01 | blup | 52 | 0.02 | 2.1e-03 | 5.8 | -5.2 | 2.3e-07 | -0.89 | 0.01 | 0.95 | FALSE |