[Hub]/) : Traits : Waist circumference : →

chr1:752,566-2,573,199

Best TWAS P=4.13e-11 · Best GWAS P=1.23e-08 conditioned to 0.145

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	RP1-283E3.4	0.65	0.14	lasso	9	0.33	5.1e-28	-3.1	-5.5	2.9e-08	-0.09	0.98	0.00	FALSE
2	GTEx	Adipose Visceral Omentum	CALML6	0.13	0.03	lasso	5	0.03	1.6e-02	-5.3	-5.3	1.4e-07	0.50	0.05	0.77	FALSE
3	GTEx	Adipose Visceral Omentum	RP1-283E3.4	0.26	0.05	enet	25	0.16	1.5e-08	-3.1	-5.9	4.4e-09	0.17	0.15	0.08	FALSE
4	GTEx	Artery Aorta	RP1-283E3.4	0.60	0.12	lasso	9	0.27	3.2e-15	-3.1	-5.2	2.4e-07	-0.07	0.52	0.06	FALSE
5	GTEx	Artery Coronary	AL645728.2	0.18	0.03	lasso	3	0.00	4.2e-01	-4.6	-5.3	1.4e-07	0.51	0.03	0.27	FALSE
6	GTEx	Brain Cerebellar Hemisphere	NADK	0.18	0.11	lasso	7	0.09	3.1e-03	-5.3	-5.3	8.7e-08	0.94	0.03	0.64	FALSE
7	GTEx	Brain Cerebellar Hemisphere	RP5-890O3.9	0.24	0.02	lasso	9	0.02	1.3e-01	-5.4	6.1	9.3e-10	-0.81	0.02	0.54	TRUE
8	GTEx	Cells Transformed fibroblasts	RP1-283E3.4	0.59	0.13	lasso	8	0.29	3.0e-22	2.4	-5.7	1.4e-08	0.01	0.98	0.00	FALSE
9	GTEx	Esophagus Mucosa	TMEM52	0.17	0.18	lasso	2	0.20	2.9e-13	-5.5	5.5	4.8e-08	-0.81	0.02	0.98	FALSE
10	GTEx	Esophagus Mucosa	RP1-283E3.4	0.53	0.12	enet	20	0.22	4.1e-15	-3.1	-6.1	1.0e-09	0.03	0.98	0.00	FALSE
11	GTEx	Esophagus Muscularis	RP1-283E3.4	0.46	0.14	enet	23	0.24	1.6e-14	-3.1	-6.6	4.1e-11	-0.01	0.94	0.00	TRUE
12	GTEx	Lung	NADK	0.07	0.03	lasso	3	0.02	8.5e-03	4.9	-5.3	1.2e-07	0.85	0.07	0.80	FALSE
13	GTEx	Muscle Skeletal	NADK	0.06	0.00	enet	9	0.00	1.3e-01	-5.3	-5.5	4.7e-08	0.84	0.03	0.89	FALSE
14	GTEx	Muscle Skeletal	TMEM52	0.11	0.08	lasso	6	0.10	7.2e-10	-5.5	6.0	1.6e-09	-0.89	0.02	0.98	FALSE
15	GTEx	Muscle Skeletal	SLC35E2B	0.35	0.06	lasso	4	0.19	3.2e-18	-2.9	5.5	4.1e-08	0.13	0.97	0.00	FALSE
16	GTEx	Nerve Tibial	CALML6	0.13	0.12	lasso	2	0.11	4.4e-08	-5.3	-5.3	9.3e-08	0.57	0.04	0.96	FALSE
17	GTEx	Pancreas	CALML6	0.21	0.08	lasso	4	0.06	2.2e-03	-5.3	-5.3	1.2e-07	0.52	0.05	0.89	FALSE
18	GTEx	Skin Not Sun Exposed Suprapubic	TMEM52	0.19	0.18	lasso	4	0.14	2.6e-08	4.9	5.2	1.9e-07	-0.79	0.09	0.91	FALSE
19	GTEx	Skin Not Sun Exposed Suprapubic	RP1-283E3.4	0.48	0.12	lasso	5	0.31	1.1e-17	-3.1	-5.7	1.0e-08	-0.07	0.43	0.15	FALSE
20	GTEx	Skin Sun Exposed Lower leg	TMEM52	0.17	0.14	lasso	7	0.15	2.0e-12	5.2	5.5	3.9e-08	-0.81	0.07	0.93	FALSE
21	GTEx	Spleen	TMEM52	0.47	0.21	lasso	5	0.22	2.3e-06	-4.6	-5.4	7.9e-08	0.46	0.08	0.78	FALSE
22	GTEx	Thyroid	RP1-283E3.4	0.59	0.04	lasso	10	0.22	3.8e-17	-3.1	-5.9	3.8e-09	-0.06	0.71	0.04	FALSE
23	ROSMAP	Brain Pre-frontal Cortex	C1orf222	0.11	0.14	enet	18	0.14	1.8e-17	-5.1	5.6	2.7e-08	-0.74	0.04	0.96	FALSE
24	ROSMAP	Brain Pre-frontal Cortex	MMP23B	0.05	0.04	lasso	2	0.03	1.9e-04	-5.7	-5.7	1.3e-08	1.00	0.01	0.99	FALSE
25	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TMEM52	0.02	0.01	blup	37	0.02	6.6e-03	-5.4	5.3	8.8e-08	-0.77	0.01	0.72	FALSE