Best TWAS P=1.41e-07 · Best GWAS P=1.66e-07 conditioned to 0.341
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | DNAJC11 | 0.03 | 0.03 | lasso | 5 | 0.04 | 3.1e-05 | 5.1 | 5.1 | 2.7e-07 | 0.87 | 0.02 | 0.97 | FALSE |
2 | GTEx | Breast Mammary Tissue | GPR153 | 0.13 | 0.03 | lasso | 5 | 0.01 | 1.3e-01 | 5.0 | -5.3 | 1.4e-07 | -0.93 | 0.03 | 0.75 | TRUE |
3 | GTEx | Testis | THAP3 | 0.22 | 0.19 | lasso | 5 | 0.22 | 3.1e-10 | 5.0 | 5.1 | 2.9e-07 | 0.94 | 0.01 | 0.99 | FALSE |