[Hub]/) : Traits : Waist circumference : ← →

chr16:3,301,360-5,706,977

Best TWAS P=7.72e-15 · Best GWAS P=3.14e-21 conditioned to 4.28e-09

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Aorta	UBN1	0.18	0.15	lasso	4	0.14	6.8e-08	6.3	-5.5	3.8e-08	-0.04	0.17	0.82	FALSE
2	GTEx	Artery Tibial	UBN1	0.20	0.06	lasso	7	0.07	4.8e-06	5.7	-5.1	2.9e-07	-0.02	0.67	0.32	FALSE
3	GTEx	Brain Cerebellar Hemisphere	ZNF500	0.27	0.13	enet	13	0.12	4.4e-04	1.9	5.4	5.7e-08	0.00	0.15	0.60	TRUE
4	GTEx	Brain Putamen basal ganglia	ROGDI	0.41	0.38	lasso	7	0.30	7.9e-08	4.9	-5.4	8.4e-08	-0.06	0.09	0.89	FALSE
5	GTEx	Esophagus Mucosa	UBN1	0.12	0.06	lasso	3	0.08	5.1e-06	5.9	-6.0	1.5e-09	-0.05	0.12	0.87	FALSE
6	GTEx	Esophagus Muscularis	UBN1	0.18	0.19	lasso	4	0.19	9.1e-12	6.3	-6.1	9.4e-10	-0.04	0.54	0.46	FALSE
7	GTEx	Nerve Tibial	UBN1	0.14	0.12	lasso	4	0.11	5.6e-08	6.2	-6.2	4.4e-10	-0.04	0.43	0.56	TRUE
8	GTEx	Skin Not Sun Exposed Suprapubic	UBN1	0.22	0.16	lasso	4	0.14	2.5e-08	5.9	-5.2	1.8e-07	-0.04	0.57	0.43	FALSE
9	GTEx	Skin Sun Exposed Lower leg	PPL	0.10	0.04	lasso	6	0.02	5.7e-03	5.9	5.7	1.6e-08	0.05	0.10	0.66	FALSE
10	GTEx	Skin Sun Exposed Lower leg	UBN1	0.16	0.15	lasso	5	0.17	9.5e-14	6.3	-5.7	9.2e-09	-0.05	0.46	0.54	FALSE
11	ROSMAP	Brain Pre-frontal Cortex	ROGDI	0.26	0.30	enet	27	0.30	5.2e-39	-4.7	-5.2	2.2e-07	-0.03	1.00	0.00	FALSE
12	ROSMAP	Brain Pre-frontal Cortex	RP11-462G12.1	0.11	0.07	enet	18	0.06	1.1e-08	-9.2	-7.8	7.7e-15	0.86	0.00	1.00	TRUE
13	The Cancer Genome Atlas	Colon Adenocarcinoma	UBN1	0.05	0.04	enet	7	0.05	4.2e-04	-6.2	5.7	9.7e-09	0.06	0.02	0.74	FALSE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ROGDI	0.03	0.04	lasso	3	0.03	1.6e-04	5.7	-5.6	2.5e-08	0.01	0.04	0.91	FALSE
15	The Cancer Genome Atlas	Brain Lower Grade Glioma	ROGDI	0.05	0.02	lasso	2	0.03	6.0e-04	-4.5	-5.8	7.5e-09	-0.05	0.06	0.08	FALSE