[Hub]/) : Traits : Waist circumference : ← →

chr20:24,485,525-26,182,690

Best TWAS P=4.64e-12 · Best GWAS P=2.6e-09 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ABHD12	0.10	0.17	blup	405	0.17	1.7e-20	5.4	6.3	2.4e-10	-0.19	0.11	0.89	FALSE
2	CommonMind	Brain Pre-frontal Cortex	NINL	0.19	0.17	lasso	20	0.23	1.2e-27	5.5	6.4	1.3e-10	-0.16	0.08	0.92	FALSE
3	GTEx	Adipose Visceral Omentum	ABHD12	0.06	0.00	lasso	8	0.00	4.6e-01	5.5	5.7	1.3e-08	-0.14	0.09	0.62	FALSE
4	GTEx	Artery Aorta	NINL	0.17	0.18	lasso	6	0.19	1.5e-10	5.5	6.1	1.1e-09	-0.15	0.08	0.92	FALSE
5	GTEx	Artery Tibial	ABHD12	0.12	0.12	enet	25	0.15	7.1e-12	5.1	5.1	3.0e-07	-0.07	0.16	0.83	TRUE
6	GTEx	Brain Caudate basal ganglia	ABHD12	0.09	0.05	enet	13	0.04	2.9e-02	5.5	5.5	3.4e-08	-0.15	0.09	0.73	FALSE
7	GTEx	Brain Cerebellar Hemisphere	PYGB	0.20	0.16	lasso	5	0.12	5.8e-04	5.1	-5.1	2.7e-07	0.14	0.10	0.68	TRUE
8	GTEx	Brain Cerebellar Hemisphere	NINL	0.17	0.07	enet	18	0.11	1.1e-03	5.3	5.3	1.1e-07	-0.31	0.09	0.64	FALSE
9	GTEx	Breast Mammary Tissue	ABHD12	0.08	0.09	lasso	5	0.09	3.3e-05	5.5	5.9	4.9e-09	-0.14	0.09	0.88	FALSE
10	GTEx	Breast Mammary Tissue (Male)	ABHD12	0.06	0.01	lasso	3	0.02	1.3e-01	5.0	5.6	1.7e-08	-0.13	0.04	0.23	FALSE
11	GTEx	Cells Transformed fibroblasts	ABHD12	0.24	0.33	lasso	4	0.35	6.3e-27	5.6	5.6	2.3e-08	-0.16	0.06	0.94	FALSE
12	GTEx	Heart Atrial Appendage	ABHD12	0.07	0.06	enet	16	0.06	1.0e-03	5.4	5.2	1.5e-07	-0.15	0.10	0.88	FALSE
13	GTEx	Heart Left Ventricle	ABHD12	0.15	0.14	lasso	10	0.12	4.0e-07	5.4	5.8	8.6e-09	-0.18	0.09	0.91	FALSE
14	GTEx	Liver	ABHD12	0.20	0.20	lasso	19	0.15	7.3e-05	5.2	5.2	2.0e-07	-0.15	0.12	0.87	FALSE
15	GTEx	Lung	ABHD12	0.06	0.00	lasso	6	0.00	2.7e-01	5.5	5.9	3.2e-09	-0.12	0.06	0.82	FALSE
16	GTEx	Nerve Tibial	PYGB	0.26	0.15	enet	11	0.14	5.7e-10	4.9	-5.3	1.2e-07	0.09	0.57	0.43	TRUE
17	GTEx	Nerve Tibial	ABHD12	0.24	0.44	lasso	11	0.44	5.1e-34	5.4	-5.2	2.3e-07	0.16	0.14	0.86	FALSE
18	GTEx	Pancreas	ENTPD6	0.11	0.05	enet	23	0.05	5.0e-03	5.6	-5.7	1.0e-08	0.15	0.08	0.86	TRUE
19	GTEx	Pituitary	ABHD12	0.27	0.31	enet	25	0.31	1.8e-08	5.2	5.9	3.6e-09	-0.14	0.12	0.88	FALSE
20	GTEx	Skin Sun Exposed Lower leg	ABHD12	0.07	0.03	lasso	10	0.05	7.3e-05	4.7	5.9	4.5e-09	-0.19	0.13	0.85	FALSE
21	GTEx	Testis	ABHD12	0.21	0.18	enet	25	0.23	1.1e-10	5.4	5.7	1.2e-08	-0.14	0.10	0.90	FALSE
22	GTEx	Thyroid	ABHD12	0.05	0.04	lasso	5	0.03	3.9e-03	5.2	-5.4	6.2e-08	0.16	0.12	0.85	FALSE
23	ROSMAP	Brain Pre-frontal Cortex	PYGB	0.20	0.10	bslmm	414	0.11	3.2e-14	5.3	-5.4	5.3e-08	0.07	0.14	0.86	FALSE
24	ROSMAP	Brain Pre-frontal Cortex	ABHD12	0.26	0.35	enet	35	0.42	7.9e-58	5.0	5.6	1.8e-08	-0.14	0.13	0.87	FALSE
25	ROSMAP	Brain Pre-frontal Cortex	ENTPD6	0.32	0.10	bslmm	432	0.12	1.8e-15	5.5	6.9	4.6e-12	-0.70	0.03	0.97	TRUE
26	YFS	Blood	ABHD12	0.15	0.35	bslmm	390	0.34	2.2e-118	5.5	5.6	1.9e-08	-0.16	0.08	0.92	TRUE
27	YFS	Blood	NINL	0.04	0.03	lasso	8	0.03	2.8e-10	5.4	5.2	1.9e-07	-0.07	0.17	0.83	FALSE
28	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	PYGB	0.08	0.04	blup	74	0.06	1.0e-03	5.2	-5.7	1.3e-08	0.14	0.07	0.75	TRUE
29	The Cancer Genome Atlas	Glioblastoma Multiforme	ABHD12	0.14	0.10	lasso	5	0.13	1.1e-04	4.8	5.1	3.1e-07	-0.15	0.06	0.89	FALSE
30	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ABHD12	0.03	0.01	blup	77	0.01	8.7e-03	4.3	5.6	1.9e-08	-0.14	0.06	0.77	FALSE
31	The Cancer Genome Atlas	Brain Lower Grade Glioma	ABHD12	0.04	0.06	blup	77	0.06	2.2e-07	5.4	5.5	3.9e-08	-0.15	0.06	0.94	FALSE
32	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ABHD12	0.07	0.05	blup	77	0.05	2.4e-03	5.2	5.2	1.9e-07	-0.15	0.05	0.84	FALSE
33	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	ABHD12	0.08	0.09	blup	80	0.09	1.7e-06	5.3	5.2	2.5e-07	-0.12	0.06	0.94	FALSE
34	The Cancer Genome Atlas	Thyroid Carcinoma	NINL	0.08	0.14	lasso	11	0.13	2.9e-12	5.5	-5.3	1.0e-07	0.16	0.02	0.98	FALSE
35	The Cancer Genome Atlas	Thyroid Carcinoma	PYGB	0.10	0.08	lasso	7	0.07	1.4e-07	4.8	-5.5	3.1e-08	0.10	0.21	0.78	FALSE