Hub : Genes

NINL

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1950	0.0470	0.0e+00	0.172	0.228	0.225	0.229	0.230	2.2e-20	2.1e-27	6.4e-27	1.9e-27	1.2e-27
2	GTEx	Adipose Subcutaneous	0.1120	0.0520	7.2e-04	0.013	NA	0.023	NA	0.017	2.9e-02	NA	5.2e-03	NA	1.5e-02
3	GTEx	Artery Aorta	0.1660	0.0510	4.8e-11	0.177	NA	0.170	NA	0.187	5.2e-10	NA	1.2e-09	NA	1.5e-10
4	GTEx	Artery Tibial	0.5841	0.0943	8.6e-07	0.050	NA	0.086	NA	0.110	7.9e-05	NA	2.9e-07	NA	6.0e-09
5	GTEx	Brain Cerebellar Hemisphere	0.1700	0.0740	5.9e-04	0.068	NA	0.107	NA	0.058	8.2e-03	NA	1.1e-03	NA	1.3e-02
6	GTEx	Cells Transformed fibroblasts	0.0670	0.0420	7.5e-03	-0.003	NA	0.013	NA	-0.001	6.2e-01	NA	3.4e-02	NA	4.0e-01
7	GTEx	Heart Left Ventricle	0.0812	0.0393	1.2e-03	0.028	NA	0.050	NA	0.044	1.2e-02	NA	1.1e-03	NA	2.2e-03
8	GTEx	Lung	0.0684	0.0334	8.2e-05	0.052	NA	0.011	NA	0.039	7.4e-05	NA	4.3e-02	NA	5.3e-04
9	GTEx	Nerve Tibial	0.1573	0.0495	2.4e-08	0.167	NA	0.129	NA	0.142	6.5e-12	NA	2.1e-09	NA	3.2e-10
10	GTEx	Pituitary	0.1150	0.0580	2.1e-03	0.063	NA	0.068	NA	0.110	1.2e-02	NA	8.7e-03	NA	1.0e-03
11	GTEx	Thyroid	0.1330	0.0450	1.7e-10	0.183	NA	0.196	NA	0.190	5.9e-14	NA	6.2e-15	NA	1.8e-14
12	ROSMAP	Brain Pre-frontal Cortex	0.1911	0.0479	0.0e+00	0.194	0.228	0.254	0.229	0.248	2.3e-24	7.3e-29	2.1e-32	6.1e-29	1.5e-31
13	YFS	Blood	0.0437	0.0144	2.5e-07	0.032	0.024	0.028	0.027	0.030	9.3e-11	1.5e-08	1.7e-09	2.1e-09	2.8e-10
14	TCGA	Colon Adenocarcinoma	0.2000	0.0770	1.9e-05	0.065	0.064	0.060	NA	0.078	1.3e-04	1.4e-04	2.2e-04	NA	2.7e-05
15	TCGA	Head and Neck Squamous Cell Carcinoma	0.1068	0.0507	7.6e-04	0.014	0.044	0.038	NA	0.021	9.4e-03	1.1e-05	4.0e-05	NA	1.6e-03
16	TCGA	Testicular Germ Cell Tumors	0.1130	0.0700	2.8e-03	0.029	0.068	0.039	NA	0.026	3.3e-02	2.1e-03	1.7e-02	NA	4.2e-02
17	TCGA	Thyroid Carcinoma	0.0810	0.0350	1.7e-11	0.138	0.108	0.116	NA	0.126	2.4e-13	1.2e-10	2.1e-11	NA	2.9e-12

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Bipolar Disorder (2018)	0.6	0.9	3.2	0.8	-0.7	1.3	1.0	1.8	-1.0	0.7	-0.8	-0.4	-0.6	-0.9	1.3	0.1	-0.1	0.2	-1.5	-1.3
Bipolar Disorder or Schizophrenia	0.5	1.3	2.5	1.3	-0.7	1.4	1.1	1.0	-0.5	1.6	-1.0	-1.2	-1.4	-1.2	1.3	0.7	0.3	0.7	-1.6	-1.0
Depressed Affect (Nagel 2018)	1.0	2.1	5.0	1.6	-0.9	1.7	-0.1	2.1	-2.1	0.9	-1.5	-1.0	-0.7	-1.9	1.6	-0.3	0.1	-0.6	-2.0	-2.2
Depression (Nagel 2018)	0.6	0.8	2.2	1.1	-0.4	1.3	-1.0	0.4	-1.4	0.7	-1.1	-0.7	-0.8	-1.1	0.1	-0.2	0.0	-0.0	-1.5	-1.3
Intelligence (Savage-Jansen 2018)	0.2	0.6	1.9	-0.1	0.5	-0.3	0.6	-0.4	0.6	-0.2	0.9	1.1	1.3	0.8	-1.2	0.2	-0.3	1.4	0.4	0.5
Neuroticism (Nagel 2018)	0.6	1.3	4.7	0.6	-1.2	1.1	-0.6	1.3	-2.2	0.7	-0.8	-1.3	-0.9	-0.8	0.7	-1.0	-1.0	-1.2	-1.6	-1.3
Schizophrenia (2018)	0.3	0.7	2.2	1.0	-0.3	0.8	0.5	-0.2	0.1	1.5	-0.6	-1.2	-1.3	-0.7	0.7	0.9	0.4	0.8	-0.8	-0.3
Schizophrenia vs Biploar Disorder	0.2	0.3	2.7	-0.2	1.6	0.4	-0.1	-0.5	0.2	0.1	0.5	0.3	0.1	0.5	-0.8	0.5	-0.1	0.9	-0.1	-0.1
Worry (Nagel 2018)	0.2	0.5	2.0	-0.5	-0.7	0.0	-0.6	-0.4	-0.7	0.3	-0.0	-0.8	-0.9	0.8	0.1	-0.9	-1.0	-1.4	-0.3	0.0
Alzheimer’s Disease (in mother)	0.4	0.5	3.1	-0.9	-0.8	-0.3	-1.7	0.4	-0.8	-0.3	1.1	0.4	0.6	0.5	-0.4	-0.8	-0.6	-0.5	0.0	0.1
Alzheimer’s Disease (in father)	1.6	1.8	4.2	-1.1	2.0	-1.3	-0.0	-0.4	1.4	-1.9	1.4	2.0	1.8	1.6	-1.1	-0.0	0.0	0.6	1.7	1.2
Alzheimer’s Disease (including proxy)	0.7	1.0	2.6	-1.5	0.1	-1.0	-1.6	0.0	0.0	-1.1	1.4	1.1	1.1	1.0	-0.7	-1.0	-0.7	-0.7	0.8	0.9
Crohns Disease (2017)	0.7	1.6	3.5	1.5	-0.4	1.8	0.7	1.6	-1.2	1.3	-0.9	-0.5	-0.5	-1.9	1.1	1.1	1.1	1.4	-1.7	-1.7
Irritable Bowel Disease (IBD)	0.1	0.4	0.9	-0.8	0.7	-0.3	0.5	0.2	-0.0	-0.7	0.9	1.0	0.9	0.0	-0.7	-0.5	-0.6	0.5	0.3	0.2
Ulcerative Colitis (UC)	1.1	2.1	4.4	-2.1	1.4	-1.7	-0.0	-1.1	1.0	-1.7	1.8	1.5	1.3	1.6	-1.7	-1.3	-1.4	-0.4	1.5	1.5
Major Depression (MDD)	0.2	0.3	1.0	0.5	-0.4	0.2	0.4	0.5	-0.4	0.3	-0.4	-0.3	0.1	-0.5	0.5	1.0	0.6	0.9	-0.4	-0.5
Reaction Time	2.3	4.4	9.8	1.8	-3.1	1.9	0.8	0.6	-1.2	2.8	-2.8	-3.1	-3.0	-1.9	2.2	1.3	1.8	-0.4	-2.1	-1.8
Verbal and Numeric Reasoning (VNR)	2.0	4.8	9.9	3.1	-0.7	2.9	2.8	2.3	-0.5	2.5	-1.9	-1.1	-0.9	-1.7	1.9	2.7	2.5	2.5	-2.5	-2.3
Breast Cancer	2.3	5.6	10.7	3.1	-1.8	2.9	1.6	2.9	-1.8	2.3	-2.9	-1.5	-1.1	-2.1	3.3	1.9	2.2	1.5	-2.9	-2.8
Ovarian Cancer	0.9	1.2	2.6	0.9	-1.3	0.9	-0.7	0.9	-1.2	1.1	-1.4	-1.4	-1.6	-1.2	1.2	0.1	0.4	-0.8	-1.3	-1.1
Prostate Cancer	5.1	7.2	15.0	-3.8	0.2	-3.9	-1.6	-2.2	0.8	-3.2	2.9	2.1	2.3	2.4	-2.8	-3.1	-3.0	-2.0	3.1	3.2
Age at First Birth	5.8	8.4	17.2	-3.1	1.7	-4.0	-1.0	-3.3	2.7	-3.0	3.3	2.6	2.7	3.5	-3.0	-1.6	-1.9	-0.7	4.0	4.2
Bipolar Disorder (2011)	0.6	0.6	3.4	0.4	-1.9	0.3	0.6	0.3	-0.9	0.9	-0.6	-0.8	-0.7	-1.0	0.4	-0.6	-0.4	0.2	-0.9	-0.1
Body Mass Index (BMI) (2010)	3.1	4.3	10.2	2.9	0.0	2.5	3.2	1.8	-0.0	1.8	-1.8	-0.8	-0.7	-2.0	2.0	3.1	2.9	2.4	-1.5	-2.0
Coronary Artery Disease (CAD)	0.7	0.8	1.7	1.2	-0.6	1.1	0.1	1.2	-1.1	1.1	-1.3	-0.7	-0.6	-0.8	0.9	0.3	0.3	0.6	-1.3	-0.7
Crohns Disease (2012)	0.5	0.9	2.0	1.2	-0.2	1.0	1.4	1.4	-0.6	0.6	-0.6	0.0	0.1	-1.2	1.0	0.9	0.7	1.1	-1.0	-1.0
Mean Putamen Volume	1.8	2.1	3.6	-1.8	1.3	-1.8	-0.4	-1.1	1.0	-1.9	1.2	1.6	1.4	1.9	-1.7	-1.3	-1.5	-0.3	1.6	1.5
Fasting Glucose	3.5	4.2	7.5	-1.6	2.4	-2.5	-0.5	-1.4	2.3	-2.4	2.0	2.5	2.4	2.7	-2.2	-0.7	-0.9	0.5	2.6	2.7
HbA1C	0.7	0.7	2.6	0.3	1.0	0.3	1.3	1.0	0.5	-0.7	0.9	1.6	1.6	0.4	-0.5	0.3	-0.0	1.4	0.2	-0.2
HDL Cholesterol	1.7	2.9	10.8	-1.9	-0.9	-1.3	-3.0	-0.2	-1.7	-1.1	0.5	0.0	0.0	0.1	-0.8	-3.3	-2.9	-3.1	0.0	0.3
LDL Cholesterol	4.0	6.3	11.2	3.1	-0.8	3.3	1.1	1.9	-0.6	3.2	-2.5	-2.5	-2.0	-2.5	3.3	2.9	3.3	1.1	-2.7	-3.0
Lupus	0.4	0.5	2.4	0.2	1.6	-0.1	-0.3	-0.3	1.4	-0.4	0.6	0.7	0.5	0.7	-0.7	0.8	0.8	0.8	0.6	0.3
Neuroticism (2016)	1.2	1.8	5.2	-1.2	0.4	-1.2	-0.0	-0.8	0.6	-1.4	2.1	1.6	1.8	1.4	-2.3	-0.8	-1.4	0.6	1.3	1.5
Primary Biliary Cirrhosis	0.3	0.4	1.6	0.3	-0.8	-0.3	1.2	-1.3	0.6	0.6	0.4	-0.4	-0.4	-0.5	0.3	0.3	0.4	0.1	0.4	0.4
Rheumatoid Arthritis	0.9	1.3	2.6	0.9	-0.6	1.6	-0.1	0.3	-1.2	1.4	-1.0	-1.6	-1.4	-1.4	1.4	0.4	0.5	-0.7	-1.6	-1.2
Schizophrenia (2014)	0.2	0.3	1.9	0.8	0.2	0.7	0.7	0.3	0.4	0.9	0.3	-0.2	-0.3	-0.1	0.3	0.7	-0.0	1.4	-0.7	-0.1
Triglycerides	0.7	1.2	2.8	0.2	1.7	-0.1	1.1	-1.0	1.6	-0.4	1.0	1.1	1.4	0.8	-1.0	1.2	0.9	1.5	1.1	0.7
Type 2 Diabetes (T2D) (2012)	1.0	1.2	3.6	-0.6	1.0	-0.8	-0.7	-1.0	1.1	-0.5	1.9	1.1	1.5	1.5	-1.2	0.3	-0.3	1.1	1.0	1.1
Ulcerative Colitis	2.4	3.6	6.8	-2.6	0.7	-2.3	-1.6	-1.0	0.2	-2.3	1.9	1.9	1.9	1.9	-2.1	-2.5	-2.6	-1.0	1.7	1.8
Blood Eosinophil Count	0.8	6.1	11.5	2.6	-3.0	2.1	3.1	1.5	-0.7	3.3	-2.8	-3.0	-2.9	-2.9	3.4	1.8	1.5	0.6	-2.4	-1.9
Blood Platelet Count	1.2	13.8	35.5	2.7	-4.1	3.5	-1.8	3.2	-6.0	2.7	-4.7	-3.6	-3.7	-4.7	3.1	-1.4	-0.8	-2.5	-5.7	-4.4
Blood Red Count	0.4	3.4	10.7	0.8	3.0	0.5	1.3	-2.3	3.2	1.0	-0.2	-0.0	-1.1	1.5	-1.1	3.2	1.8	3.3	0.5	0.7
Blood White Count	0.8	5.8	14.6	2.0	-2.4	2.2	-0.5	3.1	-3.8	2.2	-2.5	-2.1	-1.6	-3.7	2.0	-0.7	-0.6	-0.7	-3.5	-3.0
Heel T-Score	0.5	4.2	9.5	-2.8	1.5	-2.7	-1.1	-2.3	1.7	-2.8	1.4	1.6	1.5	1.9	-2.1	-1.4	-0.9	-2.4	3.1	1.9
BMI	3.4	20.0	42.4	6.5	-1.5	6.0	4.2	4.4	-1.0	4.8	-3.4	-2.6	-2.1	-4.9	4.5	5.6	5.6	4.4	-4.6	-5.3
Height	0.8	14.9	31.1	5.6	-0.3	5.4	3.3	3.6	-1.9	3.9	-3.7	-2.2	-2.1	-3.7	3.9	4.4	4.6	3.7	-4.5	-4.8
Waist Hip Ratio (WHR)	1.2	5.4	12.3	3.2	-0.7	3.3	1.9	3.5	-1.8	2.1	-2.6	-1.3	-1.4	-2.5	2.2	1.8	1.5	1.7	-3.0	-3.0
Systolic Blood Pressure	0.7	3.5	10.3	-1.1	2.9	-1.4	1.4	-3.1	3.2	-0.9	1.7	1.2	0.6	1.4	-1.4	1.4	0.7	1.1	2.7	2.1
Smoking Status	2.9	6.9	21.1	2.8	-3.3	2.8	0.1	1.9	-3.0	2.7	-2.9	-2.7	-2.1	-4.6	2.6	0.5	1.3	-0.3	-3.3	-3.1
Allergy or Eczema	3.5	9.3	19.8	-3.6	2.4	-3.5	-2.3	-1.0	1.2	-4.4	3.2	3.8	3.7	3.6	-2.5	-3.1	-3.5	-1.3	3.2	2.8
Cardiovascular Disease	0.1	0.3	1.0	-0.8	0.3	-0.5	-0.3	-0.8	-0.0	-0.6	1.0	0.5	0.3	-0.2	-1.0	-0.5	-0.7	-0.3	0.6	0.3
Hypothyroidism (self reported)	0.5	1.2	6.6	1.2	0.4	0.7	2.1	0.5	1.0	1.0	0.4	0.4	0.6	-0.0	0.1	1.7	1.2	2.6	-0.3	-0.1
Respiratory disease	1.0	2.2	5.7	1.8	-1.6	1.8	1.1	2.2	-1.6	1.2	-1.2	-1.0	-0.5	-2.4	1.5	0.4	0.8	0.1	-1.7	-2.0
Type 2 Diabetes (T2D) (2018)	1.0	1.8	4.6	-1.2	1.2	-1.1	-1.2	0.8	-0.2	-1.7	1.5	2.1	2.2	1.1	-1.3	-1.3	-1.9	0.6	0.6	0.9
Lung FEV1/FVC ratio	1.0	5.3	17.2	-0.7	3.9	-1.2	1.4	-3.3	4.1	-0.7	1.5	1.3	0.9	3.0	-1.5	2.4	1.4	2.4	2.7	2.3
Lung FVC	3.5	17.6	34.2	-4.8	2.1	-5.5	-2.0	-4.9	3.9	-4.4	4.6	4.0	3.6	5.5	-4.6	-2.2	-3.3	-0.3	5.4	5.8
Neuroticism	0.6	1.5	3.3	0.9	-1.7	1.2	-0.3	1.0	-1.8	1.3	-0.8	-1.6	-1.2	-1.2	1.1	-0.9	-0.9	-1.2	-1.6	-1.4
Chronotype (morning person)	0.1	0.3	1.9	-0.4	0.5	-0.5	-0.2	-0.3	1.1	-0.4	0.4	0.2	0.1	1.4	-0.1	0.2	-0.1	-0.2	0.7	0.7
Hair Pigment	0.2	6.3	25.7	-0.8	-3.0	-0.4	-2.3	-2.7	-1.9	1.1	-2.7	-3.9	-4.9	-0.8	0.8	-2.0	-1.3	-5.1	-0.7	0.5
Tanning	0.2	2.2	11.0	0.8	-1.5	0.6	-1.0	3.3	-2.3	-0.3	0.8	1.4	2.5	-1.5	0.1	-0.7	-0.7	1.6	-1.4	-0.8
Hand grip strength (left)	1.1	2.9	8.6	0.5	1.8	-0.2	1.9	-0.9	2.7	-0.2	2.0	1.7	1.8	1.4	-1.4	2.1	1.8	2.9	1.4	1.0
Number of treatments/medications taken	0.1	0.1	0.4	-0.1	0.6	-0.1	0.4	-0.2	0.4	-0.3	0.3	0.3	0.2	-0.2	-0.4	0.0	-0.4	0.5	0.5	0.6
Average weekly spirits intake	0.6	0.7	2.4	1.0	-0.3	1.0	0.3	1.0	-0.5	0.8	-1.1	-0.6	-0.5	-1.1	1.5	0.8	0.9	0.5	-0.8	-0.9
Sensitivity / hurt feelings	0.2	0.3	1.6	0.4	-0.3	0.5	-0.2	1.2	-0.8	0.0	0.2	0.3	0.4	0.1	-0.1	-0.5	-0.8	0.4	-0.6	-0.5
Frequency of depressed mood in last 2 weeks	0.1	0.2	1.3	0.2	-0.4	0.1	-1.1	-0.7	-0.4	0.3	0.1	-0.3	-0.2	-0.1	-0.8	-0.4	-0.4	0.0	-0.3	0.0
Hearing difficulty/problems: Yes	1.2	1.8	3.9	-1.8	-0.8	-1.6	-2.0	0.0	-0.2	-1.7	1.3	1.2	1.4	0.9	-1.4	-1.9	-1.6	-0.9	1.1	1.3
Relative age of first facial hair	0.5	1.0	3.2	0.9	-0.9	1.1	0.4	-0.4	-0.4	1.2	-1.2	-1.5	-1.8	-1.0	0.8	0.8	1.0	-0.7	-0.8	-0.8
Other serious medical condition/disability diagnosed by doctor	1.5	1.9	4.1	-1.0	1.8	-1.3	1.5	-0.7	2.0	-1.5	1.6	1.8	1.4	1.4	-0.7	0.1	-0.5	0.9	1.8	1.7
Ever used hormone-replacement therapy (HRT)	5.4	6.8	11.6	3.1	-1.6	3.2	1.6	2.4	-2.0	3.0	-3.3	-2.8	-2.8	-3.4	3.4	1.7	1.8	0.4	-3.1	-2.7
Ever had hysterectomy (womb removed)	0.5	0.6	1.5	0.7	-1.2	0.3	-0.1	-0.1	-0.1	0.7	-1.0	-1.2	-1.2	-1.1	1.2	0.5	0.8	-0.4	-0.3	-0.1
Systolic blood pressure, automated reading	1.7	4.9	16.9	2.5	1.9	2.3	3.7	0.5	1.7	1.8	-1.4	-0.7	-1.2	-1.4	2.0	4.1	3.5	2.7	-0.5	-1.2
Eye problems/disorders: Diabetes related eye disease	1.3	1.4	2.8	0.8	-1.1	1.3	1.1	1.6	-1.1	1.2	-1.4	-1.2	-1.2	-1.3	1.5	0.5	0.5	0.0	-1.6	-1.7
Angina	0.8	1.1	2.2	1.2	-0.1	1.5	0.0	1.4	-0.9	0.9	-1.1	-0.5	-0.5	-1.0	1.2	0.9	1.3	0.7	-1.3	-1.5
Medication for hormone replacement therapy	0.5	0.5	2.0	-0.6	-0.7	-0.9	-0.3	-1.4	0.6	-0.1	0.6	-0.2	-0.0	0.2	-0.8	-0.8	-0.9	-0.5	0.7	1.2
Vitamin and mineral supplements	1.6	2.2	4.5	1.5	-1.6	1.5	1.1	1.4	-1.6	2.0	-1.3	-1.7	-1.5	-1.8	1.6	0.4	0.6	0.3	-2.1	-1.7
Supplements: Zinc	0.4	0.4	2.1	-0.0	0.1	-0.8	-0.2	-0.7	1.5	-0.5	0.3	0.7	0.8	0.7	-0.3	0.5	0.6	0.7	1.0	0.7
Medication: Co-codamol	1.2	1.4	3.5	-1.3	1.9	-0.8	0.1	-0.2	-0.2	-1.7	1.4	1.5	1.4	0.9	-1.6	-1.3	-1.4	-0.7	0.9	0.7
Medication: Metformin	0.2	0.3	1.5	0.4	-0.3	0.3	0.6	1.2	-0.8	0.1	-0.5	0.4	0.4	-0.6	0.1	-0.1	-0.5	0.9	-0.8	-0.4
Diabetes (father)	2.3	2.8	6.8	-2.2	0.9	-2.2	-0.1	-2.6	1.7	-1.7	1.9	1.2	0.8	1.2	-2.0	-0.9	-1.1	-0.4	2.5	2.4
Diabetes (mother)	1.9	2.4	9.2	0.5	1.4	0.0	1.4	-0.8	2.7	0.2	0.8	0.6	0.6	0.4	-0.3	3.0	2.9	2.8	1.5	0.5
Severe depression (siblings)	1.2	1.3	2.5	1.5	-1.2	1.5	0.2	0.2	0.0	1.5	-0.7	-1.3	-1.2	-1.6	0.9	1.3	1.4	0.6	-1.1	-1.2
Pack years adult smoking proportion	2.8	4.2	9.5	1.6	-2.1	2.2	-1.0	2.7	-2.7	1.4	-2.3	-1.8	-1.7	-3.1	1.8	-0.1	0.5	-1.0	-2.9	-2.9
Impedance of leg (right)	0.4	1.7	5.5	-1.1	-2.0	-1.0	-2.0	-1.5	-0.8	0.6	-0.6	-1.8	-1.6	-0.5	0.0	-1.6	-0.9	-2.3	0.0	0.6
Leg fat-free mass (left)	2.2	11.4	25.0	5.0	0.3	4.5	3.9	3.6	-0.4	2.9	-2.5	-1.0	-0.8	-3.1	3.2	4.6	4.5	4.2	-3.3	-3.9
Trunk fat percentage	8.8	35.2	63.1	7.9	-2.9	7.6	4.8	6.1	-2.8	6.5	-6.5	-4.7	-4.4	-7.1	6.6	6.0	6.3	3.7	-6.8	-6.9
Hand grip strength (right)	0.9	2.4	8.3	1.0	2.2	0.4	1.8	-0.0	2.2	-0.2	1.3	1.6	1.6	1.0	-0.8	2.4	1.9	2.9	0.8	0.3
Townsend deprivation index at recruitment	0.4	0.6	1.4	1.2	0.1	0.8	0.6	1.1	-0.1	0.6	-0.9	-0.1	0.0	-0.4	0.9	1.0	1.1	0.9	-0.7	-0.9
Current tobacco smoking	1.5	2.4	6.0	1.4	-1.5	1.8	-0.3	1.4	-2.4	1.4	-1.4	-1.3	-1.2	-2.4	1.0	-0.4	-0.5	-0.3	-2.4	-2.1
Average weekly fortified wine intake	0.5	0.5	2.6	-0.9	0.3	-0.4	-0.8	-0.6	-0.9	-0.8	-0.0	-0.0	-0.1	-0.2	-0.5	-1.4	-1.0	-1.6	0.0	-0.0
Maternal smoking around birth	2.9	4.2	7.7	2.5	-1.3	2.5	0.6	1.7	-1.2	2.5	-2.2	-2.2	-2.1	-2.8	2.4	1.9	2.2	0.6	-2.4	-2.3
Fed-up feelings	0.1	0.3	0.8	0.7	-0.3	0.3	0.1	0.8	-0.7	-0.2	-0.3	0.4	0.6	-0.6	0.2	-0.5	-0.9	0.4	-0.5	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.2	1.6	4.5	1.0	-1.5	1.4	-1.1	0.6	-2.1	1.4	-0.9	-1.4	-1.2	-1.7	0.6	-0.5	-0.3	-0.6	-1.9	-1.4
Relative age voice broke	0.4	0.5	2.6	-0.2	-1.1	-0.2	-0.3	-1.6	0.0	0.1	-0.5	-1.0	-1.1	-0.2	-0.2	-0.2	0.5	-1.6	0.4	-0.1
Taking other prescription medications	0.3	0.5	4.0	0.5	-0.2	0.3	2.0	0.2	0.3	0.8	0.3	-0.2	0.1	-0.5	0.8	0.8	0.3	1.3	-0.1	0.3
Age when periods started (menarche)	0.4	0.9	3.1	-0.7	-0.8	-0.1	-1.8	-1.2	-0.9	-0.1	-1.3	-1.2	-1.6	-0.5	-0.3	-0.8	-0.1	-1.7	-0.3	-0.2
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	2.6	-0.2	-0.6	0.2	-1.3	0.9	-1.6	-0.4	-0.7	-0.3	-0.4	-0.5	0.1	-1.6	-1.3	-1.3	-0.9	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.6	5.6	-0.9	1.2	-0.9	-0.3	0.5	1.0	-2.3	1.3	2.3	2.4	1.2	-1.0	-0.0	0.1	0.5	1.5	0.6
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	3.3	1.0	-1.1	1.2	-0.2	0.5	-1.2	1.8	-1.0	-1.5	-1.3	-1.1	0.9	0.4	0.4	0.4	-1.6	-1.0
Qualifications: CSEs or equivalent	0.1	0.2	1.7	0.0	1.3	0.3	0.3	-0.3	0.5	-0.0	0.3	0.2	-0.0	0.4	-0.5	0.3	0.1	0.2	-0.2	-0.2
Serious illness, injury or assault to yourself	0.4	0.4	2.6	0.6	-0.5	0.6	0.0	1.6	-0.9	-0.2	-0.5	0.3	0.3	-0.6	0.6	-0.3	-0.4	0.4	-0.9	-0.8
High blood pressure	0.4	1.1	4.3	-0.8	2.1	-0.5	0.4	-0.5	0.8	-1.0	1.6	1.5	1.2	0.8	-1.3	0.2	-0.3	0.9	1.0	0.6
Hayfever, allergic rhinitis or eczema	3.0	6.6	10.4	-2.9	2.0	-3.1	-1.0	-1.3	1.8	-3.2	3.1	3.1	3.2	3.2	-2.1	-2.1	-2.6	-0.4	3.0	2.9
Multivitamins +/- minerals	2.1	2.7	4.9	-1.8	0.7	-1.8	-2.2	-1.8	0.9	-1.9	1.5	1.3	1.3	1.7	-2.1	-1.5	-1.6	-1.0	2.0	1.8
Stomach or abdominal pain in last month	0.2	0.2	1.1	-0.4	0.2	-0.4	0.2	-0.6	0.5	-0.2	0.6	0.2	0.2	0.2	-0.5	-0.6	-1.0	0.2	0.3	0.8
Supplements: Glucosamine	0.1	0.1	0.4	0.4	0.2	0.4	0.2	0.3	0.3	-0.2	-0.5	0.1	-0.1	-0.4	0.6	0.4	0.4	-0.0	0.1	-0.1
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	3.0	1.1	-0.9	0.9	0.3	1.7	-1.3	0.5	-0.6	-0.1	0.2	-0.7	1.2	0.0	0.2	0.1	-1.2	-1.3
Medication: Atenolol	0.4	0.6	1.8	-0.0	1.0	-0.3	0.6	-0.0	0.9	-0.1	1.2	0.9	1.1	0.8	-0.5	0.6	0.3	1.4	0.7	0.5
Medication: Levothyroxine sodium	1.0	1.8	7.0	0.3	0.8	-0.4	2.1	-0.7	2.2	0.3	1.2	0.9	1.2	1.1	-0.7	1.7	1.1	2.7	1.2	1.2
Sitting height	2.1	14.8	30.6	5.0	-0.0	5.5	3.3	3.9	-2.4	3.5	-4.1	-2.4	-2.4	-4.2	3.8	4.0	4.5	2.3	-4.6	-5.4
Chronic bronchitis/emphysema (father)	3.0	3.5	8.9	0.3	-1.3	1.6	-1.6	2.6	-3.0	0.3	-1.7	-1.3	-1.6	-2.5	1.2	-1.6	-1.2	-3.0	-2.2	-2.1
High blood pressure (mother)	1.1	1.6	7.3	-0.8	2.7	-0.4	0.2	0.6	0.7	-1.9	1.2	2.2	1.9	1.2	-1.0	-0.1	-0.6	0.9	0.8	0.3
Body mass index (BMI)	4.3	18.3	39.3	6.3	-1.2	5.6	4.4	4.4	-0.9	4.5	-3.8	-2.5	-2.2	-4.7	4.5	5.2	5.0	4.1	-4.4	-4.7
Impedance of leg (left)	0.5	2.6	9.0	-1.7	-2.3	-1.3	-2.5	-1.4	-1.4	0.3	-0.5	-1.7	-1.6	-0.4	-0.5	-2.4	-1.7	-3.0	0.0	0.7
Leg predicted mass (left)	2.2	11.4	25.0	5.0	0.2	4.5	3.9	3.6	-0.4	2.9	-2.5	-1.0	-0.8	-3.2	3.2	4.6	4.5	4.1	-3.3	-3.9
Trunk fat mass	8.1	34.9	66.0	8.1	-2.2	7.6	5.4	5.9	-2.1	6.4	-6.0	-4.2	-3.9	-6.8	6.4	6.6	6.8	4.6	-6.5	-6.8
Waist circumference	5.7	20.8	41.3	6.4	-1.4	6.1	4.5	5.3	-1.6	4.6	-4.3	-2.5	-2.3	-5.0	4.7	5.2	4.9	4.1	-5.0	-5.3
Number of incorrect matches in round	0.3	0.4	1.7	0.3	0.3	0.8	-0.9	1.3	-0.9	0.0	-0.4	-0.0	-0.3	-0.7	0.6	-0.4	-0.8	-0.2	-0.9	-0.8
Past tobacco smoking	0.4	0.7	3.7	-0.4	1.4	-0.3	0.6	-0.5	0.8	-0.6	1.0	1.0	0.6	1.9	-0.7	0.3	-0.3	0.7	0.7	0.7
Alcohol usually taken with meals	0.7	1.2	5.3	0.0	1.6	-0.6	1.7	-0.5	2.3	-0.7	0.2	0.9	0.6	1.3	-0.5	1.0	0.8	1.0	1.4	0.9
Nervous feelings	0.3	0.6	2.9	-1.0	-0.3	-0.7	0.2	-1.0	0.6	-0.1	1.0	0.1	-0.1	1.7	-0.6	-0.5	-1.0	-0.4	0.7	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	3.8	-0.0	-0.7	0.6	-1.9	0.7	-2.0	0.1	-0.5	-0.6	-0.4	-0.7	-0.0	-1.1	-0.9	-1.1	-1.2	-1.0
Hearing difficulty/problems with background noise	2.0	3.2	8.3	-2.1	-1.4	-2.1	-2.9	-0.4	-0.1	-1.9	2.1	1.5	1.9	1.7	-1.6	-2.2	-1.8	-0.9	1.6	1.9
Hair/balding pattern: Pattern 2	0.7	1.0	3.1	-0.9	-0.4	-0.9	-1.8	-1.0	-0.7	-0.7	0.2	0.1	0.3	0.8	-1.0	-1.7	-1.4	-1.6	0.1	0.4
Had menopause	2.7	3.4	7.5	2.4	-0.0	2.7	1.4	2.4	-0.5	1.7	-2.3	-1.1	-1.5	-1.9	1.9	2.0	1.7	1.6	-2.2	-1.9
Had other major operations	0.4	0.5	2.7	-0.9	1.6	-0.5	0.4	-0.0	0.2	-1.4	0.6	1.0	0.8	0.5	-0.5	-0.2	-0.2	-0.5	0.7	0.2
Forced vital capacity (FVC)	2.7	10.5	21.8	-3.4	2.8	-4.1	-0.5	-3.5	3.8	-3.7	3.5	3.4	3.2	4.0	-3.3	-0.5	-1.0	0.3	4.7	4.2
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.3	6.7	-1.2	1.7	-1.2	-0.5	0.2	1.5	-2.6	1.4	2.6	2.5	1.7	-1.3	-0.1	0.1	0.5	1.8	0.9
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	3.2	-1.1	-1.6	-1.0	-1.7	-0.7	-0.7	-0.4	0.5	-0.3	-0.1	-0.2	-1.0	-1.8	-1.6	-1.5	0.4	0.7
Qualifications: None of the above	0.7	1.6	3.6	1.2	-1.2	1.5	-0.0	1.0	-1.9	1.3	-1.4	-1.4	-1.3	-1.9	1.2	-0.0	0.0	-0.2	-1.8	-1.4
Financial difficulties in last 2 years	0.2	0.3	2.2	0.2	-1.5	-0.4	-0.1	-0.8	0.0	0.5	-0.0	-0.7	-0.4	-0.8	-0.4	-0.5	-0.3	-0.6	0.1	0.2
Mouth/teeth dental problems	0.3	0.5	2.3	-0.5	1.5	-0.4	0.2	-0.9	0.9	-0.8	0.0	0.5	-0.1	1.2	-0.8	0.3	-0.0	0.1	0.8	0.6
Heart attack	0.6	0.7	2.9	0.9	1.3	0.7	1.2	0.0	0.8	0.8	0.1	0.0	-0.2	-0.1	0.5	1.6	1.0	1.7	-0.1	-0.2
Allergy	0.7	1.5	3.8	1.2	-0.5	1.2	1.0	-0.3	0.1	1.7	-1.5	-1.6	-1.8	-1.0	0.9	1.9	2.0	0.6	-0.9	-0.9
Pain all over the body in last month	1.0	1.1	4.0	-0.6	-1.9	-0.2	-0.8	-0.2	-1.0	0.2	-0.4	-1.1	-1.2	-0.6	-0.3	-1.6	-1.8	-2.0	-0.4	0.2
Diabetes (self-reported)	0.6	0.9	3.1	-1.1	0.5	-0.8	-0.8	0.8	-0.7	-1.1	0.8	1.4	1.4	0.5	-1.0	-1.2	-1.8	0.6	0.0	0.6
Hayfever/allergic rhinitis (self-reported)	1.2	1.6	4.1	-0.7	1.8	-1.0	0.8	0.6	1.5	-1.4	1.5	2.0	2.0	1.6	-0.3	0.4	-0.0	1.3	1.4	1.0
Medication: Ramipril	0.7	0.9	3.9	0.4	2.0	0.5	1.1	0.9	0.5	-0.5	0.5	1.4	1.2	0.6	-0.1	1.1	0.5	2.0	0.1	-0.2
Medication: Simvastatin	0.7	1.0	2.3	1.5	-0.3	1.3	0.1	0.5	-0.9	1.0	-1.2	-0.8	-0.6	-1.3	0.8	1.2	1.4	0.9	-1.1	-1.1
Fluid intelligence score	1.3	2.7	6.0	2.5	-0.9	2.1	1.8	2.1	-0.7	2.0	-1.3	-0.9	-0.6	-1.2	1.6	1.8	1.4	1.9	-2.0	-1.6
Illnesses of siblings	0.4	0.5	1.6	-1.2	-0.4	-1.1	0.4	0.3	-0.3	-0.7	0.4	0.2	0.5	0.9	-0.3	-1.2	-1.1	-0.9	0.5	0.5
Neuroticism score	0.5	1.0	3.6	-0.4	-1.3	-0.1	-1.3	0.4	-1.6	0.2	0.2	-0.6	-0.2	-0.1	-0.1	-1.9	-1.9	-1.5	-0.6	-0.3
Weight	4.9	24.1	49.0	7.0	-1.1	6.4	5.0	4.9	-1.3	5.1	-4.6	-2.9	-2.6	-5.4	5.1	6.0	6.0	4.5	-5.2	-5.6
Impedance of arm (right)	0.5	2.2	9.1	-0.8	-2.1	-0.5	-2.2	-1.1	-1.3	0.7	-1.4	-2.3	-2.3	-0.9	0.4	-1.3	-0.2	-3.0	-0.3	-0.2
Arm fat percentage (right)	5.7	22.5	42.6	6.5	-2.2	6.0	4.0	4.5	-1.7	5.3	-4.9	-3.9	-3.5	-5.8	5.3	5.2	5.5	3.0	-5.0	-5.5
Trunk fat-free mass	0.9	5.1	14.1	3.2	1.3	2.7	3.3	1.6	0.7	1.7	-0.9	-0.0	0.2	-1.5	1.6	3.6	3.3	3.8	-1.6	-2.0
Hip circumference	2.8	11.9	24.6	5.0	-0.6	4.4	3.9	3.4	-0.5	3.3	-2.9	-1.6	-1.3	-3.7	3.5	4.6	4.6	3.7	-3.3	-3.9
Time employed in main current job	1.3	1.5	4.7	1.4	-0.5	1.1	0.6	-0.5	0.6	1.6	-1.3	-1.6	-1.6	-0.8	1.5	1.6	2.2	0.5	-0.6	-0.7
Alcohol intake versus 10 years previously	0.1	0.1	0.9	-0.3	1.0	0.2	-0.2	0.4	-0.0	-0.5	0.2	0.7	0.2	0.5	-0.1	0.3	-0.0	0.4	0.1	0.1
Father’s age at death	0.5	0.6	2.0	-0.8	1.1	-0.7	0.2	-0.2	1.0	-0.9	0.3	1.0	0.7	1.4	-0.1	0.5	0.5	0.5	1.0	0.7
Worrier / anxious feelings	0.1	0.2	0.7	-0.3	-0.9	-0.3	-0.3	-0.2	-0.0	0.3	0.0	-0.5	-0.5	0.8	0.1	-0.5	-0.4	-0.6	-0.0	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	1.9	-0.5	0.3	-0.4	-0.9	-0.7	-0.3	-0.7	1.0	0.9	0.8	0.6	-1.3	-1.0	-1.4	0.3	0.1	0.4
Falls in the last year	5.1	6.8	14.1	-3.4	0.9	-3.6	-2.1	-2.9	2.1	-3.2	2.6	2.0	2.0	2.0	-3.0	-2.1	-1.9	-1.8	3.8	3.2
Hair/balding pattern: Pattern 3	0.9	1.3	4.3	1.2	1.4	1.1	1.8	1.1	0.7	0.0	-0.6	0.6	0.2	-0.0	1.1	2.1	1.8	1.7	-0.1	-0.8
Number of live births	3.4	4.8	8.7	2.2	-1.8	2.5	0.2	2.7	-2.5	1.7	-2.7	-2.0	-1.8	-2.8	2.9	0.6	1.3	-0.9	-2.9	-2.9
Forced expiratory volume in 1-second (FEV1)	4.2	14.1	27.3	-3.9	3.8	-4.6	-0.8	-4.2	4.5	-4.0	3.9	3.9	3.6	4.8	-4.0	-0.6	-1.3	0.5	5.2	4.7
Pulse rate	0.3	0.4	3.5	0.3	1.9	0.2	1.0	-0.0	0.2	0.0	0.2	0.6	0.5	0.3	-0.6	0.2	-0.3	1.1	-0.3	-0.1
Happiness	0.3	0.4	2.8	-0.2	-0.6	-0.2	0.2	-1.7	0.6	0.6	0.5	-0.6	-0.7	0.0	-0.9	0.1	-0.2	0.1	0.5	0.9
Noisy workplace	1.7	2.1	4.8	-1.3	2.2	-1.0	-0.2	-0.9	1.5	-1.9	1.6	2.1	1.9	1.5	-1.8	-0.0	-0.2	0.9	1.6	1.1
Qualifications: A levels/AS levels or equivalent	0.5	1.2	3.9	-0.1	0.7	-0.7	1.9	-1.0	2.0	-0.6	0.8	0.9	0.7	1.3	-0.1	1.2	1.4	0.9	1.5	0.7
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	4.2	-0.7	2.0	-0.7	-0.3	-0.1	0.4	-1.9	0.2	1.5	1.4	0.4	-1.0	-0.4	-0.1	-0.1	0.7	0.2
Mouth/teeth dental problems: Dentures	2.6	4.3	9.0	2.3	-0.8	2.7	1.3	2.3	-1.7	2.3	-2.0	-1.7	-1.6	-3.0	2.4	1.6	1.6	0.9	-2.7	-2.7
Asthma	1.4	2.7	7.8	1.9	-1.5	2.0	1.6	2.8	-1.6	1.2	-1.5	-0.7	-0.4	-2.1	1.9	0.8	1.0	0.6	-1.9	-2.2
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.9	-0.5	-0.6	-0.9	-0.3	-1.4	0.6	-0.5	0.9	0.3	0.5	0.3	-0.8	-0.3	-0.1	-0.1	1.1	0.9
Medication: Cholesterol lowering	0.3	0.5	2.9	0.9	1.2	0.8	-0.1	0.2	-0.2	0.1	0.2	0.7	0.6	-0.1	-0.3	0.8	0.6	1.7	-0.4	-0.5
Depression (self-reported)	1.2	1.4	5.7	-0.8	-1.2	-0.2	-1.3	0.5	-2.1	-0.2	-0.6	-0.7	-0.6	-0.8	0.3	-2.1	-1.7	-2.4	-0.7	-0.2
Medication: Lansoprazole	1.7	1.9	4.1	-1.5	0.8	-1.3	-1.6	0.0	-0.3	-1.9	1.3	1.5	1.8	1.1	-1.9	-2.0	-1.6	-1.2	0.9	0.7
Prospective memory result	1.4	1.7	5.1	0.1	2.3	-0.2	0.8	-0.6	1.7	-0.6	1.5	1.6	1.5	1.6	-0.5	1.3	1.1	2.0	1.1	0.7
Lung cancer (father)	1.2	1.4	5.7	-1.0	1.0	-0.9	0.3	0.7	0.1	-1.8	1.4	2.3	2.4	1.2	-0.9	-0.7	-0.7	1.0	0.8	0.5
Illnesses of mother	0.4	0.5	2.6	-0.0	-1.6	-0.5	0.2	-0.3	-0.3	0.6	-0.5	-1.1	-0.8	-0.6	0.7	-0.6	-0.4	-0.9	0.1	0.6
Forced expiratory volume in 1-second (FEV1), Best measure	4.9	15.7	29.8	-4.2	4.1	-4.8	-0.6	-4.4	4.4	-4.5	4.3	4.2	3.8	5.2	-4.3	-0.9	-1.6	0.3	5.5	4.8
Pulse wave Arterial Stiffness index	0.2	0.2	0.6	0.6	0.6	0.5	0.1	-0.0	-0.4	0.1	0.1	0.3	0.6	-0.6	-0.2	-0.1	-0.1	0.8	-0.5	-0.3
Impedance of arm (left)	0.3	1.5	6.4	-1.0	-1.5	-0.7	-2.1	-1.1	-0.9	0.3	-1.1	-1.6	-1.8	-0.5	0.1	-1.2	-0.3	-2.5	-0.0	0.1
Arm fat mass (right)	6.2	25.3	51.2	7.2	-1.7	6.5	5.0	5.0	-1.3	5.4	-4.8	-3.4	-3.0	-5.7	5.4	5.9	6.0	4.2	-5.2	-5.7
Trunk predicted mass	0.9	5.4	14.3	3.3	1.2	2.8	3.4	1.7	0.7	1.8	-1.0	-0.1	0.1	-1.6	1.7	3.7	3.4	3.8	-1.6	-2.1
Standing height	0.5	4.8	10.8	2.8	0.1	2.8	2.1	1.6	-0.8	2.1	-2.3	-1.4	-1.4	-2.0	2.1	2.8	3.3	2.0	-2.3	-2.7
Length of working week for main job	0.5	0.6	2.5	0.7	-0.9	0.8	-0.3	0.3	-0.7	0.7	-0.6	-0.9	-0.8	-1.6	0.5	0.3	0.8	-0.4	-0.6	-1.1
Exposure to tobacco smoke at home	1.1	1.2	4.5	0.6	-1.2	0.9	-0.6	1.2	-2.1	0.6	-0.9	-0.8	-0.5	-1.4	0.6	-1.1	-0.6	-1.0	-1.7	-1.5
Breastfed as a baby	2.5	3.1	6.8	-2.6	-0.9	-2.6	-1.5	-1.6	1.0	-1.9	1.3	0.9	0.9	2.0	-1.6	-2.0	-1.8	-2.0	2.2	2.1
Tense / ‘highly strung’	0.6	1.0	3.6	-1.2	-0.8	-0.7	-1.3	-0.2	-0.8	-0.5	0.5	-0.1	0.0	0.8	-0.7	-1.7	-1.9	-1.7	0.2	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	1.3	2.0	6.4	-1.7	-0.6	-1.5	-2.1	-0.8	-1.1	-1.0	0.9	0.2	0.2	0.5	-1.1	-2.5	-2.5	-2.1	0.5	1.1
Hair/balding pattern: Pattern 4	0.2	0.4	1.3	-0.5	0.4	0.0	-0.7	1.0	-0.7	-0.8	0.2	0.5	0.4	-0.7	-0.4	-1.1	-1.1	-0.8	-0.2	-0.2
Birth weight of first child	1.2	2.1	5.1	1.0	-1.6	1.3	0.9	0.7	-1.1	1.5	-1.9	-2.1	-2.1	-1.4	2.3	0.7	1.4	-0.8	-1.4	-1.4
Peak expiratory flow (PEF)	3.5	8.1	17.5	-1.4	3.7	-2.5	0.0	-1.1	3.7	-2.8	3.1	4.0	4.2	3.8	-2.3	1.1	0.2	3.2	3.3	2.8
Pulse wave reflection index	0.5	0.6	1.7	-0.6	-0.4	-1.1	-0.2	-1.3	0.5	-0.4	0.9	0.2	0.7	0.6	-0.5	-1.0	-0.9	-0.5	0.9	1.1
Ever highly irritable/argumentative for 2 days	0.8	0.9	2.3	1.0	-0.8	1.2	0.9	0.3	-0.9	1.0	-0.9	-1.2	-1.1	-1.5	1.0	0.4	0.5	-0.6	-1.0	-1.2
Loud music exposure frequency	0.6	0.6	2.9	-1.1	-0.1	-0.6	-1.7	-1.1	-0.3	-0.4	0.3	-0.0	-0.2	0.1	-1.3	-1.0	-1.0	-0.4	0.2	0.7
Qualifications: O levels/GCSEs or equivalent	1.3	2.1	7.0	-1.3	1.3	-1.7	0.7	-1.7	2.6	-1.4	1.1	1.0	0.6	2.0	-0.8	0.7	0.6	0.1	2.4	1.9
Mouth/teeth dental problems: Bleeding gums	1.3	1.7	9.0	0.4	-3.0	0.3	-2.1	1.0	-1.6	0.9	-0.9	-1.5	-0.9	-1.5	1.0	-0.9	-0.3	-1.2	-1.0	-0.5
Blood clot in the leg (DVT)	0.1	0.2	0.6	0.7	0.5	0.5	-0.6	0.1	-0.2	0.1	0.0	0.2	0.2	0.1	-0.3	-0.3	-0.3	0.8	-0.7	-0.2
Medication: Paracetamol	0.9	1.5	3.1	-1.5	1.3	-1.2	-0.6	-1.6	0.9	-0.9	1.7	1.0	0.8	1.1	-1.8	-0.5	-1.0	0.8	1.3	1.7
Headache pain in last month	1.8	3.0	5.9	-1.7	1.5	-2.1	-0.4	-1.6	1.5	-1.9	2.4	2.0	2.1	2.1	-1.7	-0.8	-1.2	0.6	2.3	1.9
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	2.9	0.4	-1.6	0.3	0.6	1.2	-0.9	0.4	-1.6	-1.1	-1.1	-0.7	1.7	-0.4	0.0	-1.7	-0.9	-0.9
Glaucoma (self-reported)	2.0	2.4	4.1	-1.7	-0.0	-2.0	-1.8	-0.8	0.8	-1.7	1.9	1.4	1.6	1.8	-1.7	-1.6	-1.8	-0.5	1.7	1.8
Gout (self-reported)	0.3	0.4	1.5	0.4	-1.2	0.2	-0.1	0.1	-0.9	1.1	-0.4	-0.7	-0.3	-0.3	0.8	-0.1	-0.0	0.4	-0.9	-0.2
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	5.1	0.9	-0.1	0.3	1.8	0.1	0.8	0.9	0.5	0.2	0.6	0.1	-0.0	1.4	0.9	2.3	0.0	0.3
Medication: Amlodipine	0.4	0.6	4.2	0.3	-0.9	0.6	-2.0	0.5	-1.5	0.1	0.1	0.0	0.1	-0.3	-0.5	-0.5	-0.7	0.0	-0.8	-0.6
Medication: Ventolin 100micrograms inhaler	1.5	1.9	6.7	1.3	-1.9	1.5	-0.3	2.1	-2.6	0.8	-1.2	-0.6	-0.2	-1.5	0.9	-0.7	-0.6	-0.0	-2.2	-1.9
Birth weight	0.8	1.8	3.9	1.6	0.4	1.4	1.5	-0.6	0.6	2.0	-1.1	-1.4	-1.6	-0.9	1.0	2.0	1.9	1.2	-1.0	-0.9
Chronic bronchitis/emphysema (mother)	0.8	1.0	2.9	0.7	-1.2	1.0	-0.6	1.4	-1.7	0.3	-0.8	-0.4	-0.3	-1.0	0.9	-0.6	-0.1	-0.7	-1.6	-1.5
High blood pressure (siblings)	0.0	0.1	0.3	0.0	0.2	0.2	-0.6	0.1	-0.2	-0.2	-0.0	0.2	0.3	-0.1	0.1	0.3	0.4	0.4	-0.1	-0.1
Forced vital capacity (FVC), Best measure	3.0	11.1	20.5	-3.7	3.2	-4.0	-0.5	-3.5	3.5	-3.9	3.7	3.7	3.3	4.3	-3.6	-0.9	-1.5	0.2	4.5	4.1
Body fat percentage	8.5	33.4	60.5	7.8	-2.8	7.4	4.6	5.8	-2.6	6.3	-6.2	-4.6	-4.2	-7.0	6.5	5.9	6.2	3.5	-6.5	-6.8
Leg fat percentage (right)	8.0	29.0	54.6	7.4	-2.9	6.8	4.3	5.0	-2.1	6.1	-5.5	-4.4	-3.8	-6.6	6.2	5.6	6.0	3.6	-5.9	-6.1
Arm fat-free mass (right)	1.5	7.8	18.4	4.0	1.1	3.7	3.9	3.0	-0.1	2.2	-1.6	-0.2	-0.1	-2.1	2.3	4.0	3.4	4.3	-2.6	-2.9
Exposure to tobacco smoke outside home	1.0	1.3	3.1	0.8	-1.4	0.7	-0.6	-0.0	-1.1	1.1	-1.7	-1.7	-1.6	-1.8	1.2	-0.1	0.3	-0.9	-1.1	-0.8
Comparative body size at age 10	1.6	4.3	10.3	2.2	-1.8	2.2	0.1	1.3	-2.0	2.2	-2.4	-2.4	-2.1	-3.2	2.7	0.6	1.6	-1.0	-2.5	-2.5
Number of full brothers	0.6	0.7	1.9	0.8	-1.0	0.8	-0.3	0.6	-0.7	0.5	-1.4	-0.8	-0.8	-1.3	0.7	0.5	1.1	-0.1	-0.7	-1.1
Worry too long after embarrassment	0.2	0.4	2.9	0.3	-1.7	0.1	0.2	0.3	-0.8	0.7	-0.3	-0.9	-0.4	-0.3	0.6	-0.5	-0.5	-0.8	-0.4	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.0	4.8	-0.9	0.3	-0.6	-1.8	0.4	-0.8	-0.6	0.2	0.3	0.0	0.7	-0.9	-1.8	-2.2	-1.2	-0.2	0.4
Wheeze or whistling in the chest in last year	2.4	4.3	7.8	2.6	-1.7	2.7	2.1	2.4	-1.1	2.4	-1.8	-1.9	-1.5	-2.8	2.1	1.6	1.8	0.7	-2.4	-2.5
Number of children fathered	0.8	0.9	3.1	0.7	1.8	1.1	0.9	1.0	0.1	0.1	0.3	0.7	0.7	-0.2	0.5	1.4	1.3	1.4	-0.3	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	2.7	0.6	1.6	0.5	0.6	1.0	-0.1	-0.5	-0.6	0.8	0.4	0.6	0.4	0.9	0.9	0.5	-0.2	-0.6
Age at first live birth	1.7	3.1	7.7	-1.4	2.4	-1.6	0.6	-1.5	2.4	-1.2	2.2	1.8	1.5	2.8	-1.7	0.7	0.2	1.3	2.1	2.1
Pulse wave peak to peak time	0.1	0.1	0.5	-0.3	-0.6	-0.2	0.1	0.3	0.2	0.0	-0.3	-0.4	-0.7	0.4	0.4	0.3	0.3	-0.7	0.2	0.0
Health satisfaction	0.6	0.7	2.9	-0.6	-0.1	-0.6	-0.1	-0.7	0.2	-0.2	1.7	0.7	1.1	0.3	-1.7	-0.1	-0.4	1.3	0.7	1.1
Shortness of breath walking on level ground	0.5	0.5	1.9	-0.0	-0.7	0.5	0.2	0.1	-1.1	0.2	-0.9	-0.9	-1.0	-1.4	0.3	-0.5	-0.3	-1.3	-0.6	-0.5
Qualifications: College or University degree	1.0	3.3	6.4	-2.3	0.8	-2.5	-0.2	-1.8	1.2	-1.9	1.8	1.5	1.5	2.4	-1.6	-1.6	-2.1	-0.9	2.1	2.5
Eye problems/disorders: None of the above	0.5	0.6	4.1	-0.2	-1.0	-0.8	0.2	-2.0	0.7	0.8	0.3	-0.9	-0.9	-0.0	-0.3	0.3	0.3	-0.1	0.6	1.1
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.3	0.2	-0.3	0.1	0.2	0.0	-0.3	0.2	0.5	0.1	0.6	-0.2	0.3	-0.1	0.2	0.3	-0.3	-0.1
Emphysema/chronic bronchitis	1.3	1.5	6.6	0.5	-0.7	1.2	-0.6	2.4	-2.6	-0.2	-0.8	0.1	0.2	-1.5	0.7	-1.0	-0.8	-0.5	-1.7	-1.6
Medication for pain relief, constipation, heartburn	0.2	0.4	1.8	0.6	0.9	0.5	0.3	1.3	-0.1	-0.1	-0.7	0.3	0.4	0.3	0.7	0.3	0.4	0.1	-0.6	-0.9
Neck or shoulder pain in last month	1.0	1.4	3.5	-1.1	1.9	-1.3	0.2	-1.1	1.3	-1.4	1.3	1.3	1.2	1.3	-1.2	-0.5	-0.6	0.1	1.6	1.4
Medication: Blood pressure	0.9	1.5	4.5	-0.3	2.1	-0.4	-0.3	-1.0	1.4	-0.5	1.8	1.3	1.3	1.2	-1.7	0.8	0.2	2.1	1.1	1.1
Angina (self-reported)	1.1	1.4	2.8	1.4	-0.3	1.7	0.1	1.5	-1.1	1.1	-1.2	-0.6	-0.6	-1.1	1.3	1.0	1.4	0.7	-1.5	-1.7
Migraine (self-reported)	0.3	0.4	0.9	-0.1	0.2	-0.1	0.9	-0.7	0.9	-0.1	1.0	0.3	0.3	0.2	-0.5	0.8	0.4	0.9	0.8	0.6
Medication: Ibuprofen	0.3	0.4	1.0	-0.6	-0.1	-0.8	-0.5	-1.0	0.3	-0.9	0.6	0.5	0.6	0.1	-0.7	-0.6	-0.3	-0.5	1.0	0.6
Medication: Allopurinol	0.4	0.6	2.9	0.8	-0.7	0.6	0.2	1.1	-0.6	0.9	-0.1	0.0	0.4	-0.1	0.8	0.6	0.4	1.7	-1.0	-0.3
Medication: Omeprazole	1.0	1.2	5.3	0.8	-2.3	0.8	0.1	0.7	-0.7	1.3	-0.8	-1.3	-1.2	-1.7	1.6	0.4	0.6	-0.2	-1.1	-0.7
Medication: Seretide 50 evohaler	1.0	1.2	5.1	0.2	-0.9	0.4	0.5	-0.2	-0.6	1.1	-1.4	-2.0	-2.3	-1.3	0.9	0.2	0.4	-1.7	-0.4	-0.2
Mean time to correctly identify matches	2.2	4.2	8.3	2.0	-2.5	2.2	0.5	1.1	-1.2	2.6	-2.8	-2.8	-2.9	-2.0	2.2	1.4	1.8	-0.2	-2.3	-2.0
Heart disease (mother)	0.5	0.6	2.2	0.5	0.2	1.0	0.3	0.1	-0.1	0.7	-1.1	-1.1	-1.5	-1.0	0.7	0.7	0.6	-0.6	-0.8	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	3.3	0.4	0.9	0.2	1.2	-0.1	1.8	0.1	-0.3	0.0	-0.2	0.3	0.8	1.5	1.4	0.6	0.8	0.3
Whole body fat mass	7.7	32.1	61.8	7.9	-2.2	7.3	5.2	5.7	-2.0	6.1	-5.7	-4.0	-3.6	-6.6	6.2	6.3	6.5	4.4	-6.2	-6.5
Leg fat mass (right)	7.0	27.2	54.6	7.4	-1.9	6.7	4.9	5.2	-1.5	5.5	-5.0	-3.5	-3.1	-6.0	5.7	6.1	6.2	4.3	-5.5	-6.0
Arm predicted mass (right)	1.6	8.2	17.1	4.1	0.7	3.8	3.8	3.1	-0.2	2.3	-1.8	-0.4	-0.3	-2.4	2.5	4.0	3.6	4.1	-2.7	-3.1
Pulse rate, automated reading	0.3	1.0	7.5	0.8	2.7	1.3	0.6	-0.1	-0.5	0.3	-0.7	-0.0	-0.7	-1.1	-0.6	0.8	0.1	1.2	-1.0	-1.0
Alcohol intake frequency.	0.3	0.7	3.6	-1.0	-0.3	-0.7	-1.2	0.4	-0.4	-1.0	-0.4	-0.1	-0.5	0.4	0.2	-1.1	-1.1	-1.9	0.3	0.3
Comparative height size at age 10	0.6	3.5	9.9	2.3	0.1	2.1	1.9	0.6	-0.0	2.2	-1.4	-1.2	-1.1	-1.3	1.9	3.0	3.1	2.6	-1.5	-1.5
Number of full sisters	0.9	1.1	6.2	0.0	-1.3	0.4	-0.1	1.3	-2.5	0.2	-0.5	-0.4	-0.1	-0.6	0.1	-1.5	-1.4	-1.2	-1.3	-0.9
Suffer from ‘nerves’	0.6	0.9	3.0	0.7	-1.1	1.0	1.1	-0.1	-0.6	1.7	-0.5	-1.5	-1.3	-0.4	1.1	0.4	0.0	-0.0	-1.2	-0.5
Overall health rating	0.3	0.7	4.3	0.4	1.1	0.1	0.8	0.5	0.5	0.1	1.0	1.0	1.2	0.2	-0.8	0.5	-0.2	2.1	-0.1	0.3
Chest pain or discomfort	2.5	3.6	10.5	2.3	-0.6	2.4	0.5	3.2	-1.4	1.1	-2.1	-1.0	-0.9	-2.2	2.4	1.6	2.2	0.5	-2.0	-2.5
Had major operations	0.7	0.8	2.2	-0.9	0.6	-1.1	0.3	-1.1	0.9	-0.5	1.2	0.8	0.9	1.0	-1.0	-0.4	-0.7	0.8	0.9	1.5
Age at last live birth	0.9	1.3	3.3	-1.0	1.5	-1.1	0.1	-0.4	1.2	-1.4	1.0	1.7	1.6	1.8	-0.8	0.4	0.3	0.9	1.3	1.1
Family relationship satisfaction	0.9	1.1	2.3	1.1	-1.4	0.7	1.4	-0.2	0.1	1.5	-0.9	-1.4	-1.2	-1.1	0.9	1.3	1.4	0.4	-0.5	-0.3
Leg pain on walking	0.3	0.4	2.0	0.3	0.6	0.3	1.4	0.8	0.1	-0.4	-0.1	0.6	0.7	-0.4	0.4	0.7	0.7	0.5	0.1	-0.6
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	2.3	0.3	0.5	0.5	-0.3	1.5	-0.7	-0.7	-0.3	1.0	1.0	-0.1	0.1	0.0	0.1	0.3	-0.5	-1.1
Commuting to job workplace: Car/motor vehicle	1.0	1.2	4.5	1.1	1.5	1.0	2.1	-0.8	1.1	1.1	-0.5	-0.8	-0.9	-0.6	0.8	1.7	1.4	0.9	-0.1	-0.2
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.7	-0.5	0.2	-0.6	0.8	0.2	0.6	0.0	0.5	0.4	0.4	0.7	0.2	0.2	-0.2	0.4	0.5	0.8
Medication: Aspirin	1.2	1.6	3.9	1.1	-1.7	1.1	-0.8	0.3	-1.2	1.3	-1.4	-1.8	-1.9	-2.0	0.6	0.2	0.6	-1.0	-1.3	-1.4
Supplements: Vitamin C	0.6	0.7	2.0	0.6	0.5	0.8	0.5	0.3	0.2	0.5	-1.3	-0.8	-1.1	-0.9	1.4	1.1	1.3	-0.4	-0.3	-0.6
Knee pain experienced in last month	0.4	0.6	2.0	0.8	-0.5	0.9	-0.3	0.6	-0.6	0.5	-0.8	-0.4	-0.3	-1.0	0.9	0.9	1.4	0.3	-0.6	-1.0
Hypertension (Self-reported)	0.3	0.7	2.7	-1.0	1.7	-0.5	0.3	-0.4	0.4	-1.0	1.4	1.2	0.9	0.6	-1.2	-0.2	-0.7	0.2	0.8	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	1.2	-0.3	-0.9	-0.6	-0.4	-1.1	0.3	0.2	0.3	-0.4	-0.2	-0.4	-0.4	-0.4	-0.3	-0.3	0.5	1.0
Illnesses of father: Heart disease	0.5	0.7	2.9	-0.5	1.4	-0.4	0.3	-1.0	1.7	-0.9	0.7	0.6	0.1	0.3	-0.7	0.5	0.3	-0.4	1.4	0.6
Illnesses of siblings: Diabetes	0.3	0.4	2.2	0.7	0.5	0.2	0.5	0.0	1.1	0.1	0.2	0.6	0.6	0.0	-0.2	1.0	0.5	1.5	0.2	0.3
Smoking status: Previous	0.4	0.6	2.6	0.7	-1.1	0.4	0.1	0.4	-0.1	0.7	-1.0	-0.9	-0.6	-1.6	1.2	0.5	1.0	-0.1	-0.4	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.3	1.3	-0.1	-0.0	-0.0	0.8	0.6	-1.1	-0.4	-0.2	0.2	0.5	-0.1	0.3	-0.9	-0.6	-0.9	-0.3	-0.5
Whole body fat-free mass	1.3	7.2	16.2	3.9	1.0	3.4	3.6	2.5	0.3	2.1	-1.5	-0.3	-0.1	-2.1	2.2	4.0	3.8	4.0	-2.2	-2.8
Leg fat-free mass (right)	1.4	7.7	16.9	4.1	0.5	3.7	3.3	3.2	-0.5	2.1	-2.0	-0.5	-0.3	-2.5	2.4	3.8	3.6	3.6	-2.7	-3.3
Arm fat percentage (left)	5.9	23.4	45.4	6.7	-1.8	6.2	4.3	4.8	-1.4	5.3	-4.8	-3.5	-3.2	-5.6	5.4	5.6	5.7	3.6	-5.1	-5.5
Average weekly red wine intake	0.5	0.8	3.5	1.1	0.1	0.1	1.9	-0.3	1.4	0.8	-0.6	-0.7	-0.5	-0.4	0.7	1.2	1.5	0.4	0.1	-0.1
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.7	-0.6	0.5	-0.2	-0.1	-0.4	0.4	-0.5	0.4	0.5	0.2	0.8	-0.5	0.1	0.0	0.3	0.5	0.3
Mood swings	1.2	2.2	8.2	0.9	-1.1	1.5	-0.0	2.9	-2.6	0.9	-1.4	-1.1	-0.8	-1.5	1.7	-0.6	-0.5	-0.8	-2.1	-2.0
Loneliness, isolation	0.8	1.1	2.5	1.2	-1.4	0.9	-0.7	0.4	-0.6	0.9	-1.1	-1.2	-0.9	-1.6	1.0	0.1	0.9	-1.2	-0.9	-1.4
Long-standing illness, disability or infirmity	0.7	1.0	2.3	-1.0	1.0	-1.2	0.5	-0.6	0.7	-1.3	1.2	1.2	1.3	0.4	-0.9	-1.1	-1.5	-0.1	1.0	1.4
Ever had bowel cancer screening	0.8	0.9	2.8	-0.3	0.9	-0.6	0.4	-0.3	1.3	-0.7	1.1	1.2	1.5	1.3	-0.6	0.4	0.2	1.7	1.0	1.0
Diabetes diagnosed by doctor	0.5	0.8	2.9	-1.0	0.5	-0.6	-0.7	1.2	-1.0	-1.0	0.7	1.3	1.3	0.2	-0.7	-1.1	-1.7	0.4	-0.1	0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	1.8	0.1	0.3	-0.2	1.3	-1.0	1.4	0.1	0.1	-0.3	-0.3	0.0	0.2	1.1	1.1	0.5	0.8	0.8
Friendships satisfaction	1.1	1.3	3.4	1.6	-0.6	1.2	1.7	0.3	0.3	1.8	-0.5	-1.1	-0.9	-1.1	0.7	1.6	1.4	1.4	-0.9	-0.7
Qualifications: nursing, teaching	0.2	0.2	1.2	0.1	0.2	0.5	-0.3	1.1	-0.3	-0.8	-0.2	0.5	0.5	-0.5	0.3	0.0	0.5	-0.2	-0.1	-0.7
Commuting to job workplace: Walk	2.2	2.4	4.9	-1.7	0.5	-1.9	-1.2	-1.1	1.1	-1.7	1.9	1.8	1.9	2.2	-2.0	-0.7	-0.7	0.6	1.9	1.8
Eye problems/disorders: Cataract	0.8	0.9	3.4	1.0	0.5	1.0	1.8	1.8	0.5	0.2	-0.8	0.3	0.2	-0.3	1.4	1.1	0.8	1.1	-0.5	-0.7
Mouth/teeth dental problems: Mouth ulcers	1.0	1.6	3.3	-1.4	-1.5	-1.7	-0.3	-1.2	1.1	-1.0	1.8	0.8	1.1	1.3	-0.9	-1.1	-1.2	-0.6	1.8	1.7
Medication for cholesterol	0.8	1.2	3.3	1.5	-0.3	1.1	0.7	1.1	0.3	1.1	-0.9	-0.6	-0.5	-0.6	1.5	1.6	1.8	1.3	-0.7	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.5	4.1	7.7	-2.8	2.0	-2.3	-0.4	-2.2	1.7	-2.0	2.5	1.6	1.5	2.4	-2.4	-1.1	-1.6	-0.4	2.6	2.8
Back pain experienced in last month	0.4	0.5	2.1	0.3	0.8	0.7	1.5	1.1	0.2	0.1	-0.3	-0.0	-0.3	-1.2	0.9	0.9	0.8	0.5	-0.1	-0.4
Mineral and other dietary supplements	1.1	1.5	4.7	1.4	-0.6	1.2	1.2	0.1	0.4	2.2	-0.7	-1.4	-1.3	-0.5	1.0	1.8	1.6	1.6	-1.1	-0.7
Breast cancer (self-reported)	2.5	3.0	6.2	-2.5	1.2	-2.1	0.6	-0.8	0.8	-2.4	1.7	1.8	1.5	1.9	-2.1	-1.8	-1.9	-1.2	1.9	1.9
Asthma (self-reported)	1.4	2.7	8.6	1.8	-1.7	2.0	1.3	2.9	-1.8	1.2	-1.5	-0.8	-0.4	-2.2	1.9	0.6	0.8	0.3	-1.9	-2.3
Osteoporosis (self-reported)	1.7	2.1	4.9	1.6	-0.1	1.8	1.4	1.2	-0.9	1.6	-1.8	-1.5	-1.7	-1.6	2.2	1.0	0.8	0.3	-1.9	-1.6
Osteoarthritis (self-reported)	2.8	3.6	8.8	-2.1	2.0	-1.6	-0.5	0.5	0.2	-2.8	2.4	3.0	2.7	2.1	-1.6	-1.8	-2.4	-0.1	1.4	1.2
Medication: Aspirin	1.2	1.5	3.6	1.1	-1.8	1.1	-0.8	0.6	-1.2	1.2	-1.5	-1.6	-1.8	-1.9	0.7	0.2	0.6	-0.8	-1.2	-1.4
Medication: Gliclazide	0.6	0.6	2.3	-0.7	0.3	-0.8	-0.6	-0.4	-0.1	-0.5	1.1	0.9	1.1	0.4	-1.5	-0.6	-1.1	0.8	0.4	1.0
Illnesses of father: None of the above (group 1)	0.1	0.1	1.1	-0.0	-0.4	-0.6	0.1	-1.1	-0.0	0.3	-0.3	-0.4	-0.0	0.1	-0.2	-0.3	0.0	-0.0	0.1	0.4
Smoking status: Current	1.5	2.3	6.0	1.4	-1.7	1.7	-0.3	1.3	-2.4	1.4	-1.5	-1.4	-1.3	-2.5	0.9	-0.4	-0.4	-0.5	-2.3	-2.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	8.9	18.8	34.3	-4.9	3.7	-5.1	-1.4	-4.2	4.2	-4.8	5.1	4.7	4.3	5.9	-4.9	-1.7	-2.9	0.3	5.5	5.5
Whole body water mass	1.2	7.1	15.8	3.9	1.0	3.4	3.6	2.5	0.2	2.1	-1.5	-0.3	-0.2	-2.1	2.1	4.0	3.7	4.0	-2.2	-2.8
Leg predicted mass (right)	1.4	7.2	15.8	4.0	0.5	3.6	3.2	3.1	-0.5	2.1	-1.9	-0.5	-0.4	-2.5	2.3	3.7	3.5	3.5	-2.6	-3.1
Arm fat mass (left)	6.1	25.3	50.9	7.1	-1.4	6.5	5.1	5.1	-1.2	5.2	-4.8	-3.2	-2.9	-5.7	5.3	6.1	6.0	4.3	-5.2	-5.7
Number of self-reported non-cancer illnesses	0.5	0.9	5.1	1.1	-0.0	0.9	2.3	0.9	0.4	1.0	0.2	-0.3	-0.2	-0.9	0.9	1.2	0.9	1.4	-0.4	-0.4
Average weekly champagne plus white wine intake	0.3	0.5	2.0	-0.4	1.0	-0.6	-0.2	-1.3	1.4	-0.2	0.2	-0.1	-0.4	0.3	-0.4	0.5	0.2	0.1	1.0	0.9
Miserableness	0.7	1.1	3.6	1.0	-1.3	0.9	-1.2	1.5	-1.9	0.7	-0.5	-0.7	-0.2	-1.1	0.7	-1.0	-0.7	-0.4	-1.5	-1.4
Guilty feelings	1.7	2.6	8.4	-0.8	-2.1	-0.3	-2.5	0.3	-2.5	0.1	-0.3	-1.0	-0.8	-1.0	-0.2	-2.9	-2.5	-2.9	-1.0	-0.4
Wears glasses or contact lenses	1.1	1.2	3.1	-1.1	1.8	-0.8	-0.2	-0.4	0.7	-1.2	1.5	1.6	1.5	1.2	-1.2	-0.1	-0.5	1.0	1.1	0.9
Ever taken oral contraceptive pill	0.2	0.2	1.2	0.5	0.7	0.2	1.1	0.4	-0.2	0.1	-0.1	0.4	0.6	-0.3	0.3	0.3	0.2	0.6	-0.1	-0.3
Hearing aid user	0.6	0.7	1.7	-0.5	0.7	-0.6	0.5	0.8	1.1	-1.1	0.4	1.3	1.2	1.2	-0.2	0.4	0.2	1.0	1.1	0.8
Mother’s age at death	0.6	0.7	1.8	1.0	-1.0	1.0	1.3	0.9	-0.2	1.0	-0.9	-0.6	-0.7	-0.1	1.1	0.7	0.6	0.9	-0.8	-0.5
Financial situation satisfaction	0.3	0.3	1.4	-0.2	-0.9	0.2	0.0	0.4	-1.2	0.2	-0.1	-0.4	-0.4	-0.7	-0.3	-0.8	-1.0	-0.4	-0.6	-0.2
Tinnitus: Yes, now most or all of the time	2.5	2.9	9.3	-1.5	2.5	-0.9	-0.8	0.7	0.5	-2.7	1.8	3.0	2.8	2.1	-1.8	-0.7	-1.1	0.8	1.1	0.6
Commuting to job workplace: Public transport	1.0	1.2	5.2	-0.9	0.6	-1.1	-0.4	-0.2	0.7	-0.7	1.6	1.5	1.5	2.3	-1.4	-0.4	-0.8	1.1	0.7	0.9
Eye problems/disorders: Glaucoma	0.8	1.0	2.0	-1.1	-0.1	-1.3	-1.4	-0.9	0.7	-0.9	1.1	0.7	0.9	1.2	-1.1	-1.1	-1.0	-0.6	1.0	1.2
Medication: Blood pressure	1.2	2.2	4.0	-1.9	1.4	-1.5	-0.3	-0.6	0.2	-1.9	1.7	1.9	1.7	1.6	-1.9	-1.6	-2.0	-0.6	1.2	1.1
Pain type(s) experienced in last month: Hip pain	1.0	1.2	4.2	-0.4	1.4	-0.3	-0.9	1.4	-0.4	-1.5	1.2	2.0	2.0	0.5	-0.7	-1.0	-1.2	0.9	0.2	0.2
Supplements: Fish oil (including cod liver oil)	2.3	3.0	6.9	-2.1	0.9	-2.1	-1.9	-1.0	0.6	-2.6	1.3	1.9	1.8	1.3	-1.7	-2.0	-1.8	-1.4	2.0	1.7
High cholesterol (Self-reported)	0.3	0.6	1.7	1.0	-0.3	1.1	-0.1	-0.0	-0.9	1.0	-0.7	-0.8	-1.0	-1.3	0.1	0.5	0.4	0.6	-1.0	-0.8
Medication: Bendroflumethiazide	0.1	0.1	0.3	-0.0	0.3	0.1	-0.1	-0.1	-0.2	-0.3	0.2	0.5	0.6	0.0	-0.5	0.0	0.3	0.3	-0.1	-0.2
Medication: Paracetamol	0.3	0.4	1.9	-0.9	0.6	-0.5	-0.6	-1.4	0.6	-0.2	0.7	0.1	-0.3	0.1	-0.8	0.1	-0.1	0.2	0.8	1.0
Medication: Lisinopril	0.3	0.4	2.2	0.4	0.1	-0.1	1.0	-0.5	1.1	0.9	0.7	0.0	0.3	0.1	0.2	0.8	0.4	1.5	0.2	0.6
Medication: Atorvastatin	0.2	0.2	0.6	0.4	0.6	0.8	0.1	0.6	-0.7	0.2	0.0	0.2	-0.1	-0.3	-0.1	0.2	-0.2	0.6	-0.7	-0.7
Illnesses of father: High blood pressure	0.2	0.3	0.8	-0.3	0.3	-0.1	0.7	0.2	0.6	-0.2	0.9	0.5	0.5	0.5	0.3	0.6	0.5	0.8	0.4	0.3
Alcohol drinker status: Never	0.3	0.3	1.2	0.2	0.5	0.6	-1.1	1.0	-0.8	-0.1	-0.3	0.2	0.1	0.5	0.2	0.1	0.3	0.2	-0.5	-0.8
Ever smoked	0.3	0.5	1.7	-0.4	-0.7	-0.1	-1.1	-0.0	-0.9	-0.0	-0.3	-0.6	-0.4	-1.3	-0.2	-1.1	-0.7	-1.2	-0.5	-0.4
Basal metabolic rate	1.9	10.6	22.6	4.8	0.4	4.2	4.0	3.2	-0.2	2.9	-2.4	-1.0	-0.8	-3.1	3.0	4.5	4.3	4.2	-3.1	-3.6
Leg fat percentage (left)	7.1	25.6	47.8	6.9	-2.9	6.4	4.0	5.1	-2.2	5.7	-5.2	-4.1	-3.6	-6.3	5.7	5.1	5.3	3.2	-5.7	-5.8
Arm fat-free mass (left)	2.0	10.0	20.4	4.5	0.4	4.1	4.4	3.1	-0.2	2.8	-2.4	-1.1	-1.0	-3.0	3.0	4.3	4.1	3.8	-2.9	-3.4
Number of operations (self-reported)	0.2	0.3	1.4	0.1	1.2	0.3	0.8	1.0	0.0	-0.5	-0.3	0.5	0.2	0.2	0.8	0.4	0.4	0.2	-0.1	-0.2
Average weekly beer plus cider intake	0.3	0.4	2.0	0.3	0.4	0.5	-0.5	1.4	-0.6	-0.0	-0.1	0.6	0.9	-0.3	0.2	0.5	0.7	0.9	-0.6	-0.8
Irritability	0.2	0.4	2.0	-0.4	-0.9	-0.2	-0.3	-0.3	-0.5	0.4	0.2	-0.8	-0.7	-0.3	-0.1	-1.2	-1.4	-1.0	-0.2	-0.0
Risk taking	0.5	0.7	2.3	1.2	0.8	0.7	0.8	0.3	0.5	0.3	-0.8	-0.1	-0.3	-0.6	1.2	1.5	1.5	0.6	-0.1	-0.6
Ever had prostate specific antigen (PSA) test	0.4	0.5	2.4	-0.0	-0.5	-0.6	0.4	-1.1	1.5	0.0	0.7	0.0	0.1	0.8	0.5	0.3	0.3	0.1	1.0	1.1
Fractured/broken bones in last 5 years	1.8	2.3	4.5	-1.9	1.1	-2.1	0.2	-0.5	1.1	-1.9	1.7	1.7	1.8	1.2	-1.2	-1.3	-1.7	-0.5	2.0	1.9
Age started oral contraceptive pill	0.2	0.2	0.9	-0.6	0.6	-0.3	0.5	0.5	0.2	-1.0	-0.3	0.7	0.3	0.6	0.3	0.2	-0.0	-0.1	0.5	0.5
Diastolic blood pressure, automated reading	0.4	1.1	4.2	0.8	1.9	0.6	1.6	-0.4	1.6	0.4	-0.3	-0.1	-0.5	-0.5	0.5	2.1	1.8	0.8	0.5	-0.4
Ever depressed for a whole week	0.5	0.7	2.7	-0.4	-1.5	-0.5	-1.1	-0.8	-0.6	0.1	-0.3	-0.9	-0.8	-0.4	-0.1	-1.2	-0.6	-1.6	0.0	0.4
Unable to work because of sickness or disability	1.5	1.9	6.6	-1.2	2.6	-0.9	-0.5	0.1	1.3	-2.2	1.2	2.2	1.8	1.3	-1.4	-0.6	-1.3	0.3	1.3	1.1
Commuting to job workplace: Cycle	1.3	1.5	3.3	-1.8	0.4	-1.4	-1.7	-0.1	-0.2	-1.8	1.3	1.5	1.4	1.2	-1.6	-1.2	-1.1	-0.6	1.0	0.8
Myopia	0.5	0.7	1.6	-0.5	0.7	-1.1	0.6	-0.9	1.0	-0.4	1.3	0.9	0.7	0.9	-0.8	-0.2	-1.0	0.5	0.9	1.2
Vascular/heart problems diagnosed by doctor	0.2	0.4	2.6	0.4	-1.6	0.1	-0.6	0.4	-0.4	0.4	-1.1	-0.8	-0.6	-0.3	0.8	-0.4	-0.0	-0.7	-0.5	-0.2
Cholesterol lowering medication	0.7	1.0	2.5	0.9	-0.9	1.1	0.5	0.2	-1.1	0.7	-1.4	-1.1	-1.3	-1.6	0.8	0.6	0.9	-0.8	-1.0	-1.3
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	3.1	0.4	-1.8	0.3	0.2	0.4	-0.4	0.7	-0.3	-0.8	-0.6	-1.2	1.2	0.1	0.3	-0.3	-0.5	-0.2
Pain experienced in last month	0.1	0.2	0.6	0.5	-0.8	0.3	-0.7	0.1	-0.5	0.6	-0.6	-0.7	-0.5	0.0	0.0	0.1	0.4	-0.2	-0.6	-0.4
Supplements: Calcium	0.3	0.3	1.4	0.1	1.2	0.3	0.9	0.3	1.1	-0.2	-0.2	0.1	-0.4	-0.3	0.5	0.8	0.4	0.3	0.3	0.2
Basal cell carcinoma (self-reported)	0.3	0.4	2.3	-0.3	0.5	-0.2	0.8	-1.5	0.9	-0.1	-0.2	-0.5	-0.8	0.1	-0.1	0.2	0.5	-0.9	0.6	0.3
Heart attack/myocardial infarction (self-reported)	0.6	0.8	3.5	1.0	1.3	0.6	1.2	-0.2	1.0	0.9	0.3	0.0	-0.2	0.1	0.4	1.7	1.1	1.9	-0.1	-0.1
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	1.0	0.9	0.5	0.7	-0.1	0.1	-0.2	0.3	-0.0	0.2	0.2	0.1	-0.1	-0.0	-0.0	1.0	-0.8	-0.4
Heart disease (siblings)	0.2	0.2	1.4	0.7	1.2	0.6	-0.3	0.0	0.1	-0.1	-0.5	0.2	-0.2	-0.4	-0.2	0.4	0.1	0.1	-0.5	-0.6
Alcohol drinker status: Previous	0.5	0.5	1.9	-0.4	-0.3	-0.4	-0.9	1.0	-0.4	-0.7	0.7	0.9	1.0	0.6	-0.5	-1.1	-1.4	0.0	0.0	0.3
Pack years of smoking	3.2	4.7	9.8	2.1	-1.7	2.6	-0.2	3.0	-2.4	1.7	-2.6	-1.7	-1.7	-3.1	2.2	0.6	1.1	-0.2	-3.1	-3.1
Impedance of whole body	0.5	2.6	9.2	-0.8	-2.5	-0.3	-2.1	-0.7	-1.9	0.9	-1.5	-2.3	-2.3	-1.1	0.5	-1.7	-0.8	-3.0	-0.8	-0.3
Leg fat mass (left)	6.4	24.8	50.0	7.1	-1.8	6.5	4.7	5.2	-1.6	5.2	-4.7	-3.2	-2.8	-5.8	5.3	5.7	5.7	4.2	-5.3	-5.7
Arm predicted mass (left)	1.9	9.8	20.7	4.5	0.3	4.2	4.0	3.1	-0.4	2.9	-2.3	-1.1	-0.9	-3.0	2.9	4.2	3.9	3.9	-3.1	-3.5