Best TWAS P=1.92e-08 · Best GWAS P=4e-08 conditioned to 0.0208
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | TPD52L2 | 0.03 | 0.00 | bslmm | 207 | 0.02 | 1.5e-03 | 5.2 | 5.6 | 2.6e-08 | -0.01 | 0.02 | 0.76 | FALSE |
2 | YFS | Blood | LIME1 | 0.12 | 0.19 | enet | 15 | 0.19 | 5.3e-59 | -5.5 | -5.5 | 3.1e-08 | 0.02 | 0.00 | 1.00 | FALSE |
3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SLC2A4RG | 0.03 | 0.01 | blup | 48 | 0.02 | 2.4e-03 | -4.6 | 5.4 | 8.6e-08 | -0.02 | 0.06 | 0.47 | FALSE |
4 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | C20orf11 | 0.04 | 0.00 | blup | 67 | 0.03 | 4.3e-03 | -1.7 | 5.2 | 2.3e-07 | -0.77 | 0.01 | 0.48 | TRUE |
5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | LIME1 | 0.04 | 0.05 | blup | 47 | 0.05 | 9.0e-06 | -5.5 | -5.5 | 3.2e-08 | 0.04 | 0.01 | 0.99 | FALSE |
6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SLC2A4RG | 0.05 | 0.01 | blup | 48 | 0.02 | 2.0e-03 | -5.1 | 5.2 | 2.4e-07 | -0.02 | 0.02 | 0.91 | FALSE |
7 | The Cancer Genome Atlas | Thyroid Carcinoma | ARFRP1 | 0.04 | 0.00 | blup | 51 | 0.00 | 1.3e-01 | -5.5 | 5.6 | 1.9e-08 | -0.01 | 0.01 | 0.60 | TRUE |