[Hub]/) : Traits : Waist circumference : ← →

chr1:39,182,130-40,737,589

Best TWAS P=9.01e-13 · Best GWAS P=1.38e-11 conditioned to 0.0397

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	BMP8A	0.05	0.03	lasso	3	0.02	8.8e-04	6.3	6.5	1.1e-10	0.70	0.04	0.93	FALSE
2	GTEx	Adipose Subcutaneous	PABPC4	0.15	0.04	lasso	8	0.04	3.3e-04	3.9	-5.7	1.4e-08	-0.78	0.03	0.97	FALSE
3	GTEx	Adipose Subcutaneous	RP11-69E11.4	0.14	0.08	enet	22	0.10	1.4e-08	6.3	5.2	2.0e-07	0.57	0.19	0.80	FALSE
4	GTEx	Adipose Subcutaneous	BMP8A	0.06	0.05	lasso	1	0.04	3.5e-04	5.4	5.4	5.6e-08	0.44	0.14	0.26	FALSE
5	GTEx	Adrenal Gland	PABPC4	0.20	0.09	lasso	8	0.06	3.0e-03	6.3	-7.1	9.0e-13	-0.76	0.03	0.90	TRUE
6	GTEx	Adrenal Gland	RP11-69E11.4	0.11	0.05	lasso	3	0.00	2.4e-01	5.4	6.1	1.1e-09	0.51	0.05	0.59	FALSE
7	GTEx	Artery Tibial	PABPC4	0.10	0.10	lasso	4	0.10	3.4e-08	6.3	-6.2	5.1e-10	-0.69	0.11	0.89	FALSE
8	GTEx	Brain Frontal Cortex BA9	RP11-69E11.4	0.23	0.10	lasso	6	0.11	7.2e-04	5.4	5.3	1.3e-07	0.46	0.12	0.21	FALSE
9	GTEx	Breast Mammary Tissue	PABPC4	0.13	0.02	enet	14	0.04	3.4e-03	6.3	-6.4	1.9e-10	-0.68	0.06	0.86	FALSE
10	GTEx	Breast Mammary Tissue (Female)	PABPC4	0.10	0.00	enet	9	0.01	1.5e-01	6.6	-6.8	9.1e-12	-0.77	0.04	0.38	FALSE
11	GTEx	Cells Transformed fibroblasts	PABPC4	0.07	0.09	lasso	1	0.06	2.7e-05	6.3	-6.3	2.4e-10	-0.66	0.05	0.93	FALSE
12	GTEx	Colon Transverse	RP11-69E11.4	0.23	0.12	lasso	4	0.15	1.8e-07	6.3	5.3	1.1e-07	0.66	0.11	0.88	FALSE
13	GTEx	Esophagus Mucosa	PABPC4	0.06	0.06	lasso	3	0.08	7.3e-06	6.3	-6.3	2.8e-10	-0.71	0.09	0.89	FALSE
14	GTEx	Esophagus Mucosa	RP11-69E11.4	0.18	0.06	lasso	9	0.07	2.2e-05	4.8	5.5	5.1e-08	0.64	0.61	0.38	FALSE
15	GTEx	Esophagus Muscularis	BMP8A	0.08	0.05	enet	10	0.05	3.5e-04	3.2	5.2	2.4e-07	0.68	0.15	0.80	FALSE
16	GTEx	Lung	PABPC4	0.05	0.03	lasso	3	0.02	1.3e-02	6.3	-5.9	3.6e-09	-0.63	0.14	0.67	FALSE
17	GTEx	Nerve Tibial	PABPC4	0.17	0.08	enet	12	0.05	2.7e-04	6.3	-6.2	6.5e-10	-0.69	0.09	0.90	FALSE
18	GTEx	Nerve Tibial	RP11-69E11.4	0.18	0.08	lasso	5	0.18	1.3e-12	4.9	5.6	2.2e-08	0.65	0.25	0.75	FALSE
19	GTEx	Nerve Tibial	RP11-69E11.8	0.05	0.00	lasso	3	0.01	6.9e-02	6.3	-6.5	7.2e-11	-0.71	0.04	0.84	FALSE
20	GTEx	Skin Not Sun Exposed Suprapubic	PABPC4	0.12	0.10	lasso	3	0.05	1.0e-03	6.3	-6.4	2.0e-10	-0.69	0.10	0.80	FALSE
21	GTEx	Skin Sun Exposed Lower leg	PABPC4	0.11	0.09	lasso	7	0.08	2.7e-07	6.3	-6.2	7.4e-10	-0.74	0.07	0.93	FALSE
22	GTEx	Skin Sun Exposed Lower leg	RP11-69E11.4	0.13	0.12	lasso	6	0.15	1.3e-12	5.2	5.6	2.6e-08	0.70	0.94	0.06	FALSE
23	GTEx	Spleen	RP11-69E11.4	0.25	0.12	lasso	4	0.15	9.3e-05	4.8	5.5	2.9e-08	0.67	0.15	0.67	FALSE
24	GTEx	Stomach	RP11-69E11.4	0.31	0.20	lasso	4	0.20	4.0e-10	4.8	5.2	1.5e-07	0.53	0.75	0.24	FALSE
25	GTEx	Thyroid	RP11-69E11.4	0.17	0.04	lasso	9	0.06	4.4e-05	4.8	5.3	8.7e-08	0.56	0.12	0.77	FALSE
26	METSIM	Adipose	PABPC4	0.05	0.02	lasso	6	0.03	6.0e-05	6.3	-5.3	9.5e-08	-0.69	0.09	0.90	FALSE
27	NTR	Blood	KIAA0754	0.03	0.00	bslmm	366	0.01	1.6e-03	-0.8	5.2	1.7e-07	0.56	0.04	0.88	FALSE
28	NTR	Blood	PABPC4	0.01	0.00	blup	383	0.00	2.8e-02	6.3	-6.2	4.9e-10	-0.65	0.02	0.72	FALSE
29	The Cancer Genome Atlas	Breast Invasive Carcinoma	BMP8A	0.05	0.01	lasso	6	0.02	5.5e-05	6.3	5.6	2.2e-08	0.55	0.01	0.98	FALSE
30	The Cancer Genome Atlas	Breast Invasive Carcinoma	PABPC4	0.03	0.03	lasso	2	0.04	1.3e-08	6.3	-6.2	4.2e-10	-0.60	0.00	1.00	FALSE
31	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	BMP8A	0.04	0.03	blup	48	0.04	3.5e-05	4.8	6.4	1.4e-10	0.66	0.02	0.96	FALSE
32	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PABPC4	0.03	0.01	enet	4	0.02	4.3e-03	6.3	-6.1	8.4e-10	-0.61	0.00	0.99	FALSE
33	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PABPC4	0.04	0.05	blup	31	0.04	1.2e-05	5.4	-5.9	3.1e-09	-0.50	0.02	0.97	FALSE
34	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PABPC4	0.05	0.05	enet	4	0.05	5.5e-04	6.3	-5.5	4.5e-08	-0.65	0.00	0.96	FALSE
35	The Cancer Genome Atlas	Brain Lower Grade Glioma	BMP8A	0.05	0.01	blup	48	0.04	6.8e-05	6.3	6.4	1.8e-10	0.66	0.00	0.98	FALSE
36	The Cancer Genome Atlas	Lung Adenocarcinoma	PABPC4	0.04	0.03	enet	8	0.04	4.5e-05	6.3	-6.3	2.3e-10	-0.61	0.00	1.00	FALSE
37	The Cancer Genome Atlas	Thyroid Carcinoma	PABPC4	0.09	0.07	enet	5	0.08	4.1e-08	6.3	-6.5	7.4e-11	-0.51	0.00	1.00	FALSE