Best TWAS P=5.03e-10 · Best GWAS P=4.6e-08 conditioned to 0.00138
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TMEM54 | 0.05 | 0.00 | blup | 281 | 0.02 | 4.5e-03 | 1.4 | -6.2 | 5.0e-10 | 0.41 | 0.10 | 0.28 | TRUE |
| 2 | GTEx | Cells EBV-transformed lymphocytes | PHC2 | 0.58 | 0.34 | lasso | 7 | 0.28 | 7.3e-10 | -5.1 | 5.2 | 2.3e-07 | -0.06 | 0.03 | 0.97 | FALSE |
| 3 | GTEx | Thyroid | BAI2 | 0.31 | 0.23 | lasso | 6 | 0.22 | 1.4e-16 | 5.2 | 5.2 | 2.2e-07 | 0.00 | 0.02 | 0.98 | TRUE |
| 4 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | S100PBP | 0.06 | 0.03 | blup | 48 | 0.06 | 6.8e-04 | -5.3 | 5.6 | 2.4e-08 | -0.91 | 0.01 | 0.80 | FALSE |
| 5 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | S100PBP | 0.04 | 0.04 | lasso | 4 | 0.04 | 2.3e-05 | -5.4 | 5.4 | 6.2e-08 | -1.00 | 0.01 | 0.99 | FALSE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | S100PBP | 0.06 | 0.06 | blup | 47 | 0.05 | 5.2e-06 | -5.4 | 5.3 | 1.1e-07 | -0.92 | 0.01 | 0.99 | FALSE |