[Hub]/) : Traits : Waist circumference :

chr5:12,225-1,355,058

Best TWAS P=9.87e-09 · Best GWAS P=4.3e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SDHA 0.12 0.06 bslmm 290 0.11 8.6e-14 5.3 -5.3 1.2e-07 -0.86 0.02 0.98 FALSE
2 GTEx Adipose Subcutaneous SDHA 0.10 0.09 lasso 5 0.07 1.9e-06 5.5 5.2 1.6e-07 0.98 0.01 0.99 FALSE
3 GTEx Artery Aorta PDCD6 0.26 0.17 lasso 4 0.14 2.8e-08 5.5 -5.4 6.0e-08 -0.99 0.01 0.99 FALSE
4 GTEx Brain Frontal Cortex BA9 AHRR 0.32 0.21 lasso 4 0.18 1.6e-05 5.5 5.2 1.8e-07 0.93 0.01 0.90 FALSE
5 GTEx Cells Transformed fibroblasts SDHA 0.23 0.18 lasso 2 0.17 1.6e-12 5.5 5.5 4.8e-08 1.00 0.01 0.99 FALSE
6 GTEx Cells Transformed fibroblasts CTD-2083E4.5 0.09 0.07 lasso 3 0.05 1.2e-04 5.5 -5.3 8.8e-08 -0.99 0.01 0.98 FALSE
7 GTEx Nerve Tibial CCDC127 0.05 0.01 lasso 4 0.02 2.2e-02 4.3 5.2 1.9e-07 0.86 0.03 0.84 FALSE
8 GTEx Pancreas AC026740.1 0.19 0.01 enet 14 0.08 3.6e-04 2.3 5.2 2.5e-07 0.34 0.29 0.31 TRUE
9 GTEx Thyroid CTD-2083E4.5 0.07 0.06 lasso 2 0.04 3.6e-04 5.4 -5.5 4.5e-08 -0.99 0.01 0.96 FALSE
10 GTEx Whole Blood SDHA 0.05 0.01 lasso 5 0.01 3.4e-02 4.7 -5.4 6.6e-08 -0.91 0.02 0.93 FALSE
11 YFS Blood PDCD6 0.03 0.03 bslmm 276 0.03 1.6e-09 5.4 5.7 1.1e-08 0.91 0.01 0.99 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PDCD6 0.03 0.02 blup 49 0.02 2.9e-03 5.3 5.7 9.9e-09 0.96 0.01 0.96 TRUE
13 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma LRRC14B 0.08 0.04 lasso 5 0.03 6.7e-03 5.3 5.3 9.4e-08 0.98 0.01 0.96 FALSE
14 The Cancer Genome Atlas Liver Hepatocellular Carcinoma AHRR 0.11 0.05 lasso 3 0.07 2.5e-04 5.5 5.1 2.9e-07 0.86 0.01 0.93 FALSE
15 The Cancer Genome Atlas Thyroid Carcinoma PDCD6 0.07 0.06 enet 5 0.07 2.0e-07 5.4 -5.5 3.7e-08 -0.91 0.01 0.99 FALSE
16 The Cancer Genome Atlas Thyroid Carcinoma SDHA 0.06 0.09 lasso 13 0.08 1.8e-08 5.4 5.3 9.2e-08 1.00 0.01 0.98 FALSE